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Article ; Online: Our Role in Radiation Disaster Preparedness.

Salner, Andrew L

International journal of radiation oncology, biology, physics

2017 Volume 100, Issue 4, Page(s) 849–850

MeSH term(s)	Disaster Planning/methods ; Disaster Planning/organization & administration ; Humans ; Natural Disasters ; Radiation Oncology/organization & administration ; Terrorism/trends ; United States
Language	English
Publishing date	2017-12-21
Publishing country	United States
Document type	Editorial
ZDB-ID	197614-x
ISSN	1879-355X ; 0360-3016
ISSN (online)	1879-355X
ISSN	0360-3016
DOI	10.1016/j.ijrobp.2017.12.007
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Zs.A 1218: Show issues

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Article ; Online: Feasibility of Investigational Procedures and Efficacy of a Personalized Omega-3 Dietary Intervention in Alleviating Pain and Psychoneurological Symptoms in Breast Cancer Survivors.

Xu, Wanli / Finitsis, David / Salner, Andrew / Judge, Michelle

Pain management nursing : official journal of the American Society of Pain Management Nurses

2022 Volume 24, Issue 1, Page(s) 78–88

Abstract: Background: Breast cancer survivors (BCS) are at risk for psychoneurological symptoms (PNS) and inflammation for years following cancer treatment. Fish, particularly salmon, provides a rich source of omega-3 long chain fatty acids (omega-3LC), which has ...

Abstract	Background: Breast cancer survivors (BCS) are at risk for psychoneurological symptoms (PNS) and inflammation for years following cancer treatment. Fish, particularly salmon, provides a rich source of omega-3 long chain fatty acids (omega-3LC), which has an anti-inflammatory effect. However, the benefit of omega-3LC on PNS is not well-known. Aims: This study evaluated the feasibility and the initial efficacy of a personalized meal plan with dietary omega-3LC in reducing PNS. Methods: A prospective, randomized controlled trial design (n = 46) was used to evaluate the feasibility of a personalized meal plan using two omega-3LC dose levels (high and low omega-3LC) in reducing PNS including pain, depression, fatigue, sleep, and stress. Results: The recruitment rate was 4.9% with overall retention rate of 74% and 67.1% adherence to personalized meal plan and dietary procedures. Of participants who completed the investigation, 94% completed fish adherence logs and consumed ≥70% of the assigned quantity of fish. Saliva collection was 97.8% at baseline and 100% at follow-up. BCS in the high omega-3LC group had a significant decrease in pain (p < .01), perceived stress (p < .05), sleep (p < .001), depression (p < .001), and fatigue (p < .01) over the course of intervention. There were trends of PNS improvement in the low omega-3LC group but the differences did not reach statistical significance. Conclusion: Our results support the feasibility of our investigational design, procedures, and intervention. The outcomes provide preliminary support for an expanded research effort using fish as a source of omega-3LC and personalized dietary planning as a vehicle for symptom self-management in BCS.
MeSH term(s)	Animals ; Humans ; Female ; Cancer Survivors ; Prospective Studies ; Feasibility Studies ; Fatty Acids, Omega-3/pharmacology ; Fatty Acids, Omega-3/therapeutic use ; Breast Neoplasms/complications ; Breast Neoplasms/drug therapy ; Pain/drug therapy ; Fatigue/therapy
Chemical Substances	Fatty Acids, Omega-3
Language	English
Publishing date	2022-04-18
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2213260-0
ISSN	1532-8635 ; 1524-9042
ISSN (online)	1532-8635
ISSN	1524-9042
DOI	10.1016/j.pmn.2022.03.007
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Zs.A 6269: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 514: Show issues

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Article ; Online: Pain management for post-treatment survivors of complex cancers: a qualitative study of opioids and cannabis.

Salz, Talya / Chimonas, Susan / Jinna, Sankeerth / Brens, Jessica / Kriplani, Anuja / Salner, Andrew / Rabinowits, Guilherme / Currier, Beatriz / Daly, Bobby / Korenstein, Deborah

Pain management

2024 Volume 14, Issue 2, Page(s) 87–99

Abstract: Aim: ...

Abstract	Aim:
MeSH term(s)	Humans ; Analgesics, Opioid/adverse effects ; Cannabis ; Pain Management/methods ; Chronic Pain/drug therapy ; Neoplasms/complications ; Neoplasms/drug therapy ; Survivors
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2024-02-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2617136-3
ISSN	1758-1877 ; 1758-1869
ISSN (online)	1758-1877
ISSN	1758-1869
DOI	10.2217/pmt-2023-0067
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Article ; Online: Symptom Patterning Across the Cancer Care Trajectory for Patients Receiving Chemoradiation for Head and Neck Cancer: A Retrospective Longitudinal Study Using Latent Transition Analysis.

Dunnack Yackel, Hayley / Xu, Wanli / Lee, Jung Wun / Cong, Xiaomei / Salner, Andrew / Duffy, Valerie B / Judge, Michelle P

Cancer nursing

2023

Abstract: Background: Patients with head and neck cancer (HNC) experience a multitude of symptoms because of the tumor and its treatment.: Objective: To identify the symptom patterns present in cancer treatment and survivorship periods for patients with HNC ... ...

Abstract	Background: Patients with head and neck cancer (HNC) experience a multitude of symptoms because of the tumor and its treatment. Objective: To identify the symptom patterns present in cancer treatment and survivorship periods for patients with HNC using latent class analysis. Methods: A retrospective longitudinal chart review was conducted to examine symptoms reported by patients who received concurrent chemoradiation for HNC in a regional Northeastern United States cancer institute. Latent class analysis was performed to identify the latent classes present across multiple timepoints during treatment and survivorship for the most commonly reported symptoms. Results: In 275 patients with HNC, the latent transition analysis revealed 3 latent classes for both treatment and survivorship periods: (1) mild, (2) moderate, and (3) severe symptoms. Patients were more likely to report a greater number of symptoms in a more severe latent class. During treatment, moderate and severe classes had representation of all most common symptoms: pain, mucositis, taste alterations, xerostomia, dysphagia, and fatigue. Different symptom patterns emerged for survivorship, with prominence of taste alterations and xerostomia across all classes, and all symptoms present in the severe class. The probability of symptom expression varied more in the survivorship period compared with the treatment period. Conclusions: Patients reported numerous symptoms during active treatment persisting into survivorship. Patients tended to transition to more severe symptomatology as treatment progressed and to more moderate symptomatology as survivorship evolved. Implications for practice: Examining the trend of persistent moderate symptomatology into survivorship is useful to optimize symptom management.
Language	English
Publishing date	2023-03-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	391995-x
ISSN	1538-9804 ; 0162-220X
ISSN (online)	1538-9804
ISSN	0162-220X
DOI	10.1097/NCC.0000000000001227
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Zs.A 1538: Show issues

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Article ; Online: Virtual Tumor Board to Foster Interinstitutional Head and Neck Cancer Subspecialty Care.

Hung, Tony K W / Gelblum, Daphna Y / Kuwada, Clinton A / Patel, Akshay V / Salner, Andrew / Pfister, David G / Cracchiolo, Jennifer R

JAMA otolaryngology-- head & neck surgery

2023 Volume 149, Issue 12, Page(s) 1153–1154

MeSH term(s)	Humans ; Head and Neck Neoplasms/therapy ; Specialization
Language	English
Publishing date	2023-10-25
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2701825-8
ISSN	2168-619X ; 2168-6181
ISSN (online)	2168-619X
ISSN	2168-6181
DOI	10.1001/jamaoto.2023.1941
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Ul II Zs.87: Show issues

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Article ; Online: Work-health balance of cancer survivors returning to work: A meta-ethnography.

Wu, Weizi / Yackel, Hayley Dunnack / Salner, Andrew / Chen, Ming-Hui / Judge, Michelle P / Cong, Xiaomei / Xu, Wanli

European journal of oncology nursing : the official journal of European Oncology Nursing Society

2023 Volume 68, Page(s) 102482

Abstract: Purpose: This meta-ethnography investigates the multifaceted health-related experiences of cancer survivors returning to work (RTW), recognizing the pivotal role of employment in overall well-being, particularly in the context of increasing cancer cases ...

Abstract	Purpose: This meta-ethnography investigates the multifaceted health-related experiences of cancer survivors returning to work (RTW), recognizing the pivotal role of employment in overall well-being, particularly in the context of increasing cancer cases among working-age adults. Method: Following the methodology of Noblit and Hare, a comprehensive literature search was conducted from 2013 to 2023 in databases including PubMed, Scopus, CINAHL, PsycINFO, and Embase. Qualitative studies assessing cancer survivors' experiences, motivation, concern, resilience, and need in the process of RTW were identified. Eligible studies were assessed for quality using the Critical Appraisal Skills Program Checklist, and their findings were subsequently synthesized. Results: Seventeen studies were included for analysis. The finding revealed five key themes: motivations (voluntary and involuntary), cancer-related concerns, resilience, needs for cancer healthcare support, and workplace accommodation. Voluntarily RTW was primarily linked to desires of normalcy, while involuntary RTW was often financially driven. Cancer survivors often face physical, psychological, and social challenges in the RTW process. Resilience played a crucial role in their readaptation to the workplace. Participants expressed the need for additional guidance from healthcare providers and tailored support from the workplace to facilitate a smoother RTW experience. Conclusion: Cancer survivors aspire to be actively engaged, have their specific needs addressed, and achieve success in their return-to-work endeavors. Occupational guidance and accommodation from healthcare providers and employers play a pivotal role in empowering survivors to balance cancer and work, facilitating the return-to-work process, and enhancing the quality of survivorship.
MeSH term(s)	Adult ; Humans ; Return to Work/psychology ; Cancer Survivors/psychology ; Employment/psychology ; Workplace/psychology ; Qualitative Research ; Neoplasms/psychology ; Anthropology, Cultural
Language	English
Publishing date	2023-12-02
Publishing country	Scotland
Document type	Journal Article ; Review
ZDB-ID	2017117-1
ISSN	1532-2122 ; 1462-3889
ISSN (online)	1532-2122
ISSN	1462-3889
DOI	10.1016/j.ejon.2023.102482
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Zs.A 6219: Show issues

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Article ; Online: Physician knowledge, practice patterns, and barriers encountered regarding guideline-concordant use of bone modifying agents for prostate cancer.

Mitchell, Aaron P / Persaud, Sonia / Palyca, Paul / Salner, Andrew / Farooki, Azeez / Ostroff, Jamie S / Morris, Michael J / Chimonas, Susan

The Prostate

2023 Volume 84, Issue 2, Page(s) 177–184

Abstract: Background: Guidelines recommend bone-modifying agents (BMAs) for patients with castrate-resistant prostate cancer (CRPC) and bone metastasis, but not for castrate-sensitive prostate cancer (CSPC). Physicians beliefs and practices regarding BMA therapy ... ...

Abstract	Background: Guidelines recommend bone-modifying agents (BMAs) for patients with castrate-resistant prostate cancer (CRPC) and bone metastasis, but not for castrate-sensitive prostate cancer (CSPC). Physicians beliefs and practices regarding BMA therapy are poorly understood. Methods: This was a qualitative interview study with embedded Likert-scale elements. Study participants were physicians who treat prostate cancer, located within an academic cancer center or an affiliated community-based network. Participants were asked about their experiences and practice patterns regarding BMA therapy. Participants used Likert-scale items to identify the most common barriers to guideline-concordant BMA use and the most effective potential interventions. Participants were subsequently asked to rank the three most common barriers and the three most effective interventions to reduce underuse (for CRPC) and overuse (for CSPC). Results: Nineteen physicians were invited and 15 participated; one physician did not answer some questions as outside of their practice scope. All were aware of the recommendation for BMAs in CRPC. 14% (2/14) were unaware of the recommendation against BMA use for CSPC; an additional 29% (4/14) believed that BMA use could be appropriate for CSPC depending on the metastatic disease burden. 36% (5/14) were unaware of recommendations for screening and treatment of low bone mineral density. The most common barriers (occurring "often" or "sometimes") were obtaining dental clearance (11/15) and insufficient clinic time (6/15). The interventions identified as most effective to reduce underuse were dental navigation (11/15) and electronic medical record (EMR)-based guidance (9/15). The interventions identified as most effective to reduce overuse were peer-to-peer education (14/15) and EMR-based guidance (13/15). Conclusions: Awareness of guideline recommendations for screening and treatment of low bone mineral density and against BMA use for CSPC was good, but not complete. Dental navigation, peer-to-peer education, and EMR-based guidance were preferred intervention strategies to improve guideline-concordant use.
MeSH term(s)	Male ; Humans ; Prostatic Neoplasms, Castration-Resistant ; Physicians ; Qualitative Research ; Bone Neoplasms/drug therapy ; Bone Diseases, Metabolic
Language	English
Publishing date	2023-10-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	604707-5
ISSN	1097-0045 ; 0270-4137
ISSN (online)	1097-0045
ISSN	0270-4137
DOI	10.1002/pros.24636
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Zs.A 1608: Show issues

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Article: Connecticut Cancer Partnership: the development of a statewide comprehensive control program.

Salner, Andrew L

Connecticut medicine

2012 Volume 76, Issue 6, Page(s) 327–330

MeSH term(s)	Centers for Disease Control and Prevention (U.S.) ; Connecticut ; Health Promotion/economics ; Health Promotion/organization & administration ; Humans ; Interinstitutional Relations ; Neoplasms/prevention & control ; Program Development ; Public Health ; United States
Language	English
Publishing date	2012-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	412600-2
ISSN	0010-6178
ISSN	0010-6178
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Zs.B 288: Show issues

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Article ; Online: An Integrative Review of the Role of the Oral and Gut Microbiome in Oral Health Symptomatology During Cancer Therapy.

Dunnack, Hayley J / Judge, Michelle P / Cong, Xiaomei / Salner, Andrew / Duffy, Valerie B / Xu, Wanli

Oncology nursing forum

2021 Volume 48, Issue 3, Page(s) 317–331

Abstract: Problem identification: Both chemotherapy and radiation therapy cause considerable symptom burden on patients' oral health, influencing nutritional status and quality of life. The role of the oral and gut microbiome in oral health alterations during ... ...

Abstract	Problem identification: Both chemotherapy and radiation therapy cause considerable symptom burden on patients' oral health, influencing nutritional status and quality of life. The role of the oral and gut microbiome in oral health alterations during cancer therapy is an emerging area of science in symptom management. Literature search: PubMed®, CINAHL®, and Scopus® were searched for articles published from January 2000 through July 2020. Data evaluation: Articles published in English that were focused on chemotherapy and/or radiation therapy were included in the review. Synthesis: Of the 22 identified studies, 12 described oral health symptoms during chemotherapy and radiation therapy for head and neck cancer. Ten studies assessed symptoms during treatment for a variety of solid tumors and blood cancers, with four of these describing microbial interventions for the management of oral mucositis. Interventions varied, but the results supported the benefits of probiotics and synbiotics in reducing mucositis severity. Overall, less diverse oral and gut microbiome environments were associated with increased severity of oral health symptomatology. Implications for practice: Additional research is needed to determine how the oral and gut microbiome and microbial interventions may be used to improve oral health management during cancer treatment.
MeSH term(s)	Gastrointestinal Microbiome ; Humans ; Mucositis ; Neoplasms/therapy ; Oral Health ; Quality of Life ; Stomatitis
Language	English
Publishing date	2021-08-31
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	604886-9
ISSN	1538-0688 ; 0190-535X ; 1538-0688
ISSN (online)	1538-0688 ; 0190-535X
ISSN	1538-0688
DOI	10.1188/21.ONF.317-331
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Zs.A 1818: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 414: Show issues

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Article: Lutetium Lu-177 Dotatate Flare Reaction.

Salner, Andrew L / Blankenship, Bette / Dunnack, Hayley / Niemann, Christopher / Bertsch, Helaine

Advances in radiation oncology

2020 Volume 6, Issue 1, Page(s) 100623

Abstract: Purpose: Lutetium Lu-177 dotatate is the first peptide receptor radionuclide therapy approved by the US Food and Drug Administration. Well-designed studies in Europe have shown dramatic effectiveness in improving progression-free survival in patients ... ...

Abstract	Purpose: Lutetium Lu-177 dotatate is the first peptide receptor radionuclide therapy approved by the US Food and Drug Administration. Well-designed studies in Europe have shown dramatic effectiveness in improving progression-free survival in patients with gastroenteropancreatic neuroendocrine tumors, which are progressive and generally metastatic. This therapy is a molecular targeted therapy linking a beta-emitting radioisotope to dotatate, which binds tightly to somatostatin receptors on neuroendocrine tumors cells. Various adverse effects of this therapy have been reported in the literature, including potential toxicity to renal, hepatic, and hematologic tissues and risk of second malignancy. Our study sought to explore acute adverse effects in this patient population. Methods and materials: We tracked adverse effects and patient experience in our first year of therapy experience with this new agent. Results: In our first 12 patients who received Lutetium Lu-177 dotatate, tumor flare reactions occurred in 5 patients due to worsening symptoms of bone or soft tissue metastasis. This flare reaction can be mitigated with short course of corticosteroid therapy or other strategies. Conclusions: Flare reaction is common in patients with progressive metastatic gastroenteropancreatic neuroendocrine tumors and can be managed successfully with several strategies.
Language	English
Publishing date	2020-11-26
Publishing country	United States
Document type	Journal Article
ISSN	2452-1094
ISSN	2452-1094
DOI	10.1016/j.adro.2020.11.008
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