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  1. Book: Allergologie-Handbuch

    Angerer, Peter / Saloga, Joachim

    Grundlagen und klinische Praxis ; mit 189 Tabellen ; mit Handouts für Patienten und Ärzte zum Download

    2012  

    Author's details hrsg. von Joachim Saloga ... [Unter Mitarb. von Peter Angerer ...]
    Keywords Allergologie
    Language German
    Size XVIII, 636 S. : Ill., graph. Darst.
    Edition 2. Aufl.
    Publisher Schattauer
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    Note Handouts für Patienten und Ärzte zum Download
    HBZ-ID HT016752097
    ISBN 978-3-7945-2729-8 ; 3-7945-2729-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 8138 order for loan Magazin
    2011 A 3840 order for loan Magazin

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  2. Article: Allergieakademie Autorenreferate: 35. Mainzer Allergie-Workshop - Frühjahrstagung der DGAKI 24./25. März 2023 Tagungsleitung: Joachim Saloga, Mainz

    Saloga, Joachim

    Allergologie

    2023  Volume 46, Issue 2, Page(s) 128

    Language German
    Document type Article
    ZDB-ID 547065-1
    ISSN 0344-5062
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1398: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Book: Allergologie-Handbuch

    Angerer, Peter / Saloga, Joachim

    Grundlagen und klinische Praxis ; mit 181 Tabellen

    2006  

    Author's details hrsg. von Joachim Saloga ... Unter Mitarb. von Peter Angerer
    Keywords Allergologie
    Language German
    Size XXIII, 549 S.: Ill., graph. Darst.
    Publisher Schattauer
    Publishing place Stuttgart u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT014213156
    ISBN 3-7945-1972-8 ; 978-3-7945-1972-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2005 A 4620 order for loan Magazin
    2011 A 4216 order for loan Magazin

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  4. Article ; Online: Current Strategies to Modulate Regulatory T Cell Activity in Allergic Inflammation.

    Bellinghausen, Iris / Khatri, Rahul / Saloga, Joachim

    Frontiers in immunology

    2022  Volume 13, Page(s) 912529

    Abstract: Over the past decades, atopic diseases, including allergic rhinitis, asthma, atopic dermatitis, and food allergy, increased strongly worldwide, reaching up to 50% in industrialized countries. These diseases are characterized by a dominating type 2 immune ...

    Abstract Over the past decades, atopic diseases, including allergic rhinitis, asthma, atopic dermatitis, and food allergy, increased strongly worldwide, reaching up to 50% in industrialized countries. These diseases are characterized by a dominating type 2 immune response and reduced numbers of allergen-specific regulatory T (Treg) cells. Conventional allergen-specific immunotherapy is able to tip the balance towards immunoregulation. However, in mouse models of allergy adaptive transfer of Treg cells did not always lead to convincing beneficial results, partially because of limited stability of their regulatory phenotype activity. Besides genetic predisposition, it has become evident that environmental factors like a westernized lifestyle linked to modern sanitized living, the early use of antibiotics, and the consumption of unhealthy foods leads to epithelial barrier defects and dysbiotic microbiota, thereby preventing immune tolerance and favoring the development of allergic diseases. Epigenetic modification of Treg cells has been described as one important mechanism in this context. In this review, we summarize how environmental factors affect the number and function of Treg cells in allergic inflammation and how this knowledge can be exploited in future allergy prevention strategies as well as novel therapeutic approaches.
    MeSH term(s) Allergens ; Animals ; Desensitization, Immunologic/methods ; Inflammation/metabolism ; Mice ; Rhinitis, Allergic ; T-Lymphocytes, Regulatory
    Chemical Substances Allergens
    Language English
    Publishing date 2022-05-26
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.912529
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Editorial Anaphylaxie Nur den akuten Notfall behandeln ist nicht ausreichend

    Saloga, Joachim

    Arzneimitteltherapie

    2016  Volume 34, Issue 4, Page(s) 111

    Language German
    Document type Article
    ZDB-ID 380334-x
    ISSN 0723-6913
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1854: Show issues Location:
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  6. Book ; Thesis: Eine ultrastrukturelle, zytochemische und immunzytochemische Untersuchung an den Langerhanszellen der Haut beim experimentellen Kontaktekzem des Meerschweinchens

    Saloga, Joachim

    1989  

    Author's details vorgelegt von Joachim Saloga
    Size 1 Mikrofiche
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Münster (Westfalen), Univ., Diss., 1989
    Note Manuskript: 86 Bl. : Ill., graph. Darst.
    HBZ-ID HT003754389
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1991 MB 3060 order for loan Magazin

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  7. Book: Allergologie-Handbuch

    Saloga, Joachim

    Grundlagen und klinische Praxis

    2012  

    Author's details herausgegeben von Joachim Saloga ... [et al.]
    MeSH term(s) Hypersensitivity
    Language German
    Size xviii, 636 p. :, ill.
    Edition 2. Aufl.
    Publisher Schattauer
    Publishing place Stuttgart
    Document type Book
    ISBN 9783794527298 ; 3794527291
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Article ; Online: Analysis of allergic immune responses in humanized mice.

    Bellinghausen, Iris / Saloga, Joachim

    Cellular immunology

    2016  Volume 308, Page(s) 7–12

    Abstract: Nowadays, more than 25% of the population in industrial countries are affected by IgE-mediated (atopic) allergic diseases such as allergic rhinitis, asthma and atopic eczema. Due to intensive research on basis of in vitro studies with human immune cells ... ...

    Abstract Nowadays, more than 25% of the population in industrial countries are affected by IgE-mediated (atopic) allergic diseases such as allergic rhinitis, asthma and atopic eczema. Due to intensive research on basis of in vitro studies with human immune cells and different murine in vivo models of allergy fundamental mechanisms of allergic immune responses have been elucidated during the last years. However, human studies are restricted and the immune system of mice differs from the human immune system in several aspects so that the transferability of experimental results from mice to men is limited. Humanized mice represent a new tool to analyze the interaction of human immune cells under physiological conditions as far as possible, particularly to test novel therapeutic strategies. This review summarizes the impact of humanized mouse models for the investigation and treatment of allergic diseases.
    MeSH term(s) Animals ; Asthma/immunology ; Biomedical Research ; Desensitization, Immunologic/methods ; Desensitization, Immunologic/trends ; Disease Models, Animal ; Female ; Humans ; Hypersensitivity/immunology ; Immunoglobulin E/metabolism ; Male ; Mice ; Mice, SCID ; T-Lymphocytes, Regulatory/immunology ; Transplantation Chimera
    Chemical Substances Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2016
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 80094-6
    ISSN 1090-2163 ; 0008-8749
    ISSN (online) 1090-2163
    ISSN 0008-8749
    DOI 10.1016/j.cellimm.2016.07.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 417: Show issues Location:
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  10. Article ; Online: Depletion of CD56

    Ose, Robert / Weigmann, Benno / Schuppan, Detlef / Waisman, Ari / Saloga, Joachim / Bellinghausen, Iris

    The Journal of allergy and clinical immunology

    2021  Volume 148, Issue 4, Page(s) 1081–1087.e2

    Abstract: Background: CD56-expressing natural killer (NK) cells as well as invariant NK T (iNKT) cells have been shown to either promote or inhibit allergic immune responses.: Objective: The aim of the present study was to investigate the impact of these cells ...

    Abstract Background: CD56-expressing natural killer (NK) cells as well as invariant NK T (iNKT) cells have been shown to either promote or inhibit allergic immune responses.
    Objective: The aim of the present study was to investigate the impact of these cells in a recently developed humanized mouse model of allergen-induced IgE-dependent gut and lung inflammation.
    Methods: Nonobese diabetic-severe combined immunodeficiency γ-chain knockout mice were injected intraperitoneally with human PBMCs or CD56-depleted (CD56
    Results: Allergen-specific human IgE in mouse sera, detectable only after coinjection of the respective allergen, was reduced in mice being injected with CD56
    Conclusion: These results demonstrate that allergen-specific gut and lung inflammation in PBMC-engrafted humanized mice is promoted by CD56
    MeSH term(s) Allergens/immunology ; Animals ; Betula/immunology ; CD3 Complex/immunology ; CD56 Antigen/immunology ; Colitis/immunology ; Colitis/pathology ; Colitis/physiopathology ; Colon/immunology ; Colon/pathology ; Female ; Humans ; Immunoglobulin E/blood ; Lung/immunology ; Lung/pathology ; Lung/physiopathology ; Male ; Mice, Transgenic ; Natural Killer T-Cells/immunology ; Poaceae/immunology ; Pollen/immunology ; Respiratory Hypersensitivity/immunology ; Respiratory Hypersensitivity/pathology ; Respiratory Hypersensitivity/physiopathology ; Rhinitis, Allergic, Seasonal/immunology ; Rhinitis, Allergic, Seasonal/pathology ; Rhinitis, Allergic, Seasonal/physiopathology
    Chemical Substances Allergens ; CD3 Complex ; CD56 Antigen ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2021-05-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2021.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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