Article ; Online: Screening and Treatment Outcomes in Adults and Children With Type 1 Diabetes and Asymptomatic Celiac Disease: The CD-DIET Study.
2020 Volume 43, Issue 7, Page(s) 1553–1556
Abstract: Objective: To describe celiac disease (CD) screening rates and glycemic outcomes of a gluten-free diet (GFD) in patients with type 1 diabetes who are asymptomatic for CD.: Research design and methods: Asymptomatic patients (8-45 years) were screened ... ...
| Abstract | Objective: To describe celiac disease (CD) screening rates and glycemic outcomes of a gluten-free diet (GFD) in patients with type 1 diabetes who are asymptomatic for CD. Research design and methods: Asymptomatic patients (8-45 years) were screened for CD. Biopsy-confirmed CD participants were randomized to GFD or gluten-containing diet (GCD) to assess changes in HbA Results: Adults had higher CD-seropositivity rates than children (6.8% [95% CI 4.9-8.2%, Conclusions: CD is frequently observed in asymptomatic patients with type 1 diabetes, and clinical vigilance is warranted with initiation of a GFD. |
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| MeSH term(s) | Adolescent ; Adult ; Asymptomatic Diseases ; Autoantibodies/analysis ; Autoantibodies/blood ; Biopsy ; Blood Glucose/analysis ; Blood Glucose/metabolism ; Blood Glucose Self-Monitoring ; Canada ; Celiac Disease/blood ; Celiac Disease/complications ; Celiac Disease/diagnosis ; Celiac Disease/diet therapy ; Child ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/diagnosis ; Diabetes Mellitus, Type 1/diet therapy ; Diet, Gluten-Free ; Female ; Humans ; Male ; Mass Screening ; Middle Aged ; Postprandial Period ; Serologic Tests ; Treatment Outcome ; Young Adult | ||||||||||
| Chemical Substances | Autoantibodies ; Blood Glucose | ||||||||||
| Language | English | ||||||||||
| Publishing date | 2020-04-28 | ||||||||||
| Publishing country | United States | ||||||||||
| Document type | Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't | ||||||||||
| ZDB-ID | 441231-x | ||||||||||
| ISSN | 1935-5548 ; 0149-5992 | ||||||||||
| ISSN (online) | 1935-5548 | ||||||||||
| ISSN | 0149-5992 | ||||||||||
| DOI | 10.2337/dc19-1944 | ||||||||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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