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  1. Article: Remembering the past - studies on evolution done by the genetics group at Universidade Federal do Rio Grande do Sul (UFRGS).

    Salzano, Francisco M

    Genetics and molecular biology

    2018  Volume 41, Issue 1 suppl 1, Page(s) 181–188

    Abstract: After a brief introduction about the factors that are involved in science development, and world and Brazilian evolutionary genetics, the studies developed in Porto Alegre in this area were reviewed. Four periods in the development of this group were ... ...

    Abstract After a brief introduction about the factors that are involved in science development, and world and Brazilian evolutionary genetics, the studies developed in Porto Alegre in this area were reviewed. Four periods in the development of this group were distinguished: (a) Origins and first expansion (1949-1961); (b) Second expansion (1962-1988); (c) Third expansion (1989-2001); and (d) The last 15 years (2002-present). The international Porto Alegre Biological Evolution Workshops (PABEWs), with five biannual events from 2007 o 2015, were also mentioned. The final message stressed the importance of the maintenance of this and other Brazilian groups of research through adequate finance and recognition.
    Language English
    Publishing date 2018-03-19
    Publishing country Brazil
    Document type Editorial
    ZDB-ID 1445712-x
    ISSN 1678-4685 ; 1415-4757
    ISSN (online) 1678-4685
    ISSN 1415-4757
    DOI 10.1590/1678-4685-GMB-2017-0049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Evolution of Science in a Latin-American Country: Genetics and Genomics in Brazil.

    Salzano, Francisco M

    Genetics

    2017  Volume 208, Issue 3, Page(s) 823–832

    Abstract: This article begins with a brief overview of the history of Brazil and that of Brazilian science, from the European discovery of the country in 1500 up to the early 21st century. The history of the fields of genetics and genomics, from the 1930s, is then ...

    Abstract This article begins with a brief overview of the history of Brazil and that of Brazilian science, from the European discovery of the country in 1500 up to the early 21st century. The history of the fields of genetics and genomics, from the 1930s, is then first examined from the focal point of the lives and publications of the three persons who are generally considered to be the founders of genetics in Brazil (C. A. Krug, F. G. Brieger, and A. Dreyfus), and then by 12 other researchers up to 1999. The area of molecular genetics and genomics from 2000 to present is then described. Despite the problems of underdevelopment and the periodical political and economic crises that have affected life in Brazil, the fields of genetics and genomics in Brazil can be regarded as having developed at an appropriate pace, and have contributed in several major ways to world science.
    MeSH term(s) Brazil ; Genetics/history ; Genomics/history ; History, 20th Century ; History, 21st Century ; Humans ; Science/history
    Language English
    Publishing date 2017-10-10
    Publishing country United States
    Document type Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2167-2
    ISSN 1943-2631 ; 0016-6731
    ISSN (online) 1943-2631
    ISSN 0016-6731
    DOI 10.1534/genetics.118.300690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The role of natural selection in human evolution - insights from Latin America.

    Salzano, Francisco M

    Genetics and molecular biology

    2016  Volume 39, Issue 3, Page(s) 302–311

    Abstract: A brief introduction considering Darwin's work, the evolutionary synthesis, and the scientific biological field around the 1970s and subsequently, with the molecular revolution, was followed by selected examples of recent investigations dealing with the ... ...

    Abstract A brief introduction considering Darwin's work, the evolutionary synthesis, and the scientific biological field around the 1970s and subsequently, with the molecular revolution, was followed by selected examples of recent investigations dealing with the selection-drift controversy. The studies surveyed included the comparison between essential genes in humans and mice, selection in Africa and Europe, and the possible reasons why females in humans remain healthy and productive after menopause, in contrast with what happens in the great apes. At the end, selected examples of investigations performed in Latin America, related to the action of selection for muscle performance, acetylation of xenobiotics, high altitude and tropical forest adaptations were considered. Despite dissenting views, the influence of positive selection in a considerable portion of the human genome cannot presently be dismissed.
    Language English
    Publishing date 2016-08-04
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1445712-x
    ISSN 1678-4685 ; 1415-4757
    ISSN (online) 1678-4685
    ISSN 1415-4757
    DOI 10.1590/1678-4685-GMB-2016-0020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: The evolution and genetics of Latin American populations

    Salzano, Francisco M. / Bortolini, Maria Cátira

    (Cambridge studies in biological and evolutionary anthropology ; 28)

    2002  

    Author's details Francisco M. Salzano and Maria Cátira Bortolini
    Series title Cambridge studies in biological and evolutionary anthropology ; 28
    Collection
    Keywords Lateinamerika ; Populationsgenetik
    Subject Bevölkerungsgenetik ; Evolutionsgenetik
    Language English
    Size XV, 512 S. : Ill., graph. Darst.
    Publisher Cambridge Univ. Press
    Publishing place Cambridge
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013191936
    ISBN 0-521-65275-8 ; 978-0-521-65275-9
    Database Catalogue ZB MED Medicine, Health

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  5. Article: Bioethics, population studies, and geneticophobia.

    Salzano, Francisco M

    Journal of community genetics

    2015  Volume 6, Issue 3, Page(s) 197–200

    Abstract: In any research of human populations, the classical principles of bioethics (respect for autonomy, non-maleficence, beneficence, proportionality between risks and benefits, and justice) should be strictly followed. The question of individual and/or ... ...

    Abstract In any research of human populations, the classical principles of bioethics (respect for autonomy, non-maleficence, beneficence, proportionality between risks and benefits, and justice) should be strictly followed. The question of individual and/or community rights should also be considered, as well as some neglected rights, such as the right to benefit from progress in science and technology and the right to know the nature of the group's biological and cultural history; however, in their urge to assure rights, social researchers, bioethics commissions, non-governmental organizations, and community leaders are, in many cases, crossing the limits of good sense. DNA is sometimes interpreted as synonymous to demoniac, and there is a frequent behaviour that I could only describe using a neologism: geneticophobia. There is an irrational attitude against genetic studies aiming to unravel the biological history of a given people and to classify any genome population study as "racist". This behaviour should be opposed; science and the scientific study of humankind are the only way we have to reach the socially adequate objective of the maximum of happiness to the largest number of persons.
    Language English
    Publishing date 2015-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2543127-4
    ISSN 1868-6001 ; 1868-310X
    ISSN (online) 1868-6001
    ISSN 1868-310X
    DOI 10.1007/s12687-014-0211-3
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  6. Article: Is the human species still evolving? To where?

    Salzano, Francisco M

    Genetics and molecular biology

    2012  Volume 35, Issue 4 (suppl), Page(s) 899–903

    Abstract: The questions of the title have been considered in several ways. First, indications of the traits which make us humans were considered. Then the behavior and culture concepts were examined, and the biology and culture interactions discussed, with an ... ...

    Abstract The questions of the title have been considered in several ways. First, indications of the traits which make us humans were considered. Then the behavior and culture concepts were examined, and the biology and culture interactions discussed, with an emphasis on the similarities and differences between the genetic and cultural transmissions. Next diverse types of selective pressures were reviewed, and finally pessimistic and optimistic views of our future contrasted. Vigorous action against acts which lead to exclusion and discriminatory policies against human subjects is needed.
    Language English
    Publishing date 2012-12-18
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1445712-x
    ISSN 1678-4685 ; 1415-4757
    ISSN (online) 1678-4685
    ISSN 1415-4757
    DOI 10.1590/s1415-47572012000600002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: The role of natural selection in human evolution

    Salzano, Francisco M.

    1975  

    Author's details ed. by Francisco M. Salzano
    Keywords Hominisation ; Natürliche Auslese
    Subject Natürliche Selektion ; Anthropogenese ; Mensch ; Menschwerdung ; Anthropogenie ; Humanevolution
    Language English
    Size XIII, 439 S. : graph. Darst.
    Publisher North-Holland Publ. Co ; American Elsevier
    Publishing place Amsterdam ; New York
    Publishing country Netherlands
    Document type Book
    Note Papers prepared for a conference held in Burg Wartenstein, Austria, Aug. 10 - 18, 1974
    HBZ-ID HT005242378
    ISBN 0-7204-4512-4 ; 0-444-10847-5 ; 978-0-7204-4512-1 ; 978-0-444-10847-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    1975 B 858 order for loan Magazin

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  8. Book: South American Indians

    Salzano, Francisco M. / Callegari-Jacques, Sidia M.

    a case study in evolution

    (Research monographs on human population biology ; 6)

    1988  

    Author's details Francisco M. Salzano and Sidia M. Callegari-Jacques
    Series title Research monographs on human population biology ; 6
    Collection
    Keywords Indians, South American ; Genetics, Population ; Evolution ; Südamerika ; Humanbiologie ; Indianer
    Subject Indios ; Amerikanische Indianer ; Präkolumbische Zeit ; Indio ; Amerikaner ; Amerikanische Ureinwohner ; Native Americans ; First Nations ; Premières Nations ; Erste Nationen ; First Nations People(s) ; First Americans ; Pueblos Originarios ; Anthropobiologie ; Mensch ; Biologische Anthropologie ; Physische Anthropologie
    Size XII, 259 S. : Ill., graph. Darst., Kt.
    Publisher Clarendon
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT003290241
    ISBN 0-19-857635-8 ; 978-0-19-857635-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1989 A 3924 order for loan Magazin

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  9. Article ; Online: Esterase D in Brazilian Saguinus midas niger-results and comparison with previous studies in Anthropoidea.

    Barroso, Carmem M L / Schneider, Maria P C / Sampaio, Maria I C / Salzano, Francisco M

    American journal of primatology

    2020  Volume 22, Issue 3, Page(s) 215–219

    Abstract: Four esterase D (ESD) phenotypes, presumably resulting from the segregation of three alleles with moderate polymorphic frequencies, were observed in a sample of the black handed tamarin, Saguinus midas niger, from the northern Amazonian region (Brazil). ... ...

    Abstract Four esterase D (ESD) phenotypes, presumably resulting from the segregation of three alleles with moderate polymorphic frequencies, were observed in a sample of the black handed tamarin, Saguinus midas niger, from the northern Amazonian region (Brazil). Previous surveys in the non-human Anthropoidea indicate that the ESD locus is polymorphic in at least 4 of the 19 taxonomic entities listed.
    Language English
    Publishing date 2020-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1495834-X
    ISSN 1098-2345 ; 0275-2565
    ISSN (online) 1098-2345
    ISSN 0275-2565
    DOI 10.1002/ajp.1350220307
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  10. Article: Molecular evolution and functional divergence of alcohol dehydrogenases in animals, fungi and plants.

    Thompson, Claudia E / Freitas, Loreta B / Salzano, Francisco M

    Genetics and molecular biology

    2017  Volume 41, Issue 1 suppl 1, Page(s) 341–354

    Abstract: Alcohol dehydrogenases belong to the large superfamily of medium-chain dehydrogenases/reductases, which occur throughout the biological world and are involved with many important metabolic routes. We considered the phylogeny of 190 ADH sequences of ... ...

    Abstract Alcohol dehydrogenases belong to the large superfamily of medium-chain dehydrogenases/reductases, which occur throughout the biological world and are involved with many important metabolic routes. We considered the phylogeny of 190 ADH sequences of animals, fungi, and plants. Non-class III Caenorhabditis elegans ADHs were seen closely related to tetrameric fungal ADHs. ADH3 forms a sister group to amphibian, reptilian, avian and mammalian non-class III ADHs. In fishes, two main forms are identified: ADH1 and ADH3, whereas in amphibians there is a new ADH form (ADH8). ADH2 is found in Mammalia and Aves, and they formed a monophyletic group. Additionally, mammalian ADH4 seems to result from an ADH1 duplication, while in Fungi, ADH formed clusters based on types and genera. The plant ADH isoforms constitute a basal clade in relation to ADHs from animals. We identified amino acid residues responsible for functional divergence between ADH types in fungi, mammals, and fishes. In mammals, these differences occur mainly between ADH1/ADH4 and ADH3/ADH5, whereas functional divergence occurred in fungi between ADH1/ADH5, ADH5/ADH4, and ADH5/ADH3. In fishes, the forms also seem to be functionally divergent. The ADH family expansion exemplifies a neofunctionalization process where reiterative duplication events are related to new activities.
    Language English
    Publishing date 2017-10-09
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1445712-x
    ISSN 1678-4685 ; 1415-4757
    ISSN (online) 1678-4685
    ISSN 1415-4757
    DOI 10.1590/1678-4685-GMB-2017-0047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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