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  1. Book: Allergy, immunity and tolerance in early childhood

    Wahn, Hans Ulrich / Sampson, Hugh A.

    the first steps of the atopic march

    2016  

    Author's details Hans Ulrich Wahn ; Hugh A. Sampson
    Keywords Allergy in children
    Subject code 618.9297
    Language English
    Size XIV, 392 S. : Ill., graph. Darst., 23 cm
    Publisher Elsevier Acad. Press
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT018785875
    ISBN 978-0-12-420226-9 ; 0-12-420226-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 3593 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: Advances in the Assessment and Management of Allergic Sensitization.

    Sampson, Hugh A / Hamilton, Robert G

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 10, Page(s) 3008–3009

    MeSH term(s) Humans ; Hypersensitivity/diagnosis ; Hypersensitivity/therapy ; Asthma ; Allergens
    Chemical Substances Allergens
    Language English
    Publishing date 2023-08-22
    Publishing country United States
    Document type Editorial
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.08.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Recent trends in food protein-induced enterocolitis syndrome (FPIES).

    Baker, Mary Grace / Sampson, Hugh A

    The Journal of allergy and clinical immunology

    2023  Volume 151, Issue 1, Page(s) 43–46

    Abstract: Food protein-induced enterocolitis syndrome (FPIES) was first described in detail in the late 20th century as a non-IgE-mediated food allergy characterized by delayed gastrointestinal symptoms after ingestion of a trigger food. Although the initial case ... ...

    Abstract Food protein-induced enterocolitis syndrome (FPIES) was first described in detail in the late 20th century as a non-IgE-mediated food allergy characterized by delayed gastrointestinal symptoms after ingestion of a trigger food. Although the initial case series reported infants reacting to cow's milk- and soy-based formulas, we now recognize that FPIES affects patients across the age spectrum. This brief review highlights our evolving understanding of FPIES with a discussion of triggers, epidemiology, food challenges, and pathophysiology.
    MeSH term(s) Female ; Animals ; Cattle ; Food Hypersensitivity/epidemiology ; Syndrome ; Milk ; Enterocolitis/epidemiology ; Allergens ; Dietary Proteins/adverse effects
    Chemical Substances Allergens ; Dietary Proteins
    Language English
    Publishing date 2023-01-16
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2022.11.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Conference proceedings: Classification of gastrointestinal disease of infants and children due to adverse immunologic reactions to foods

    Sampson, Hugh A.

    proceedings of a workshop ; Washington, D.C., November 16 - 17, 1998

    (Journal of pediatric gastroenterology and nutrition ; 30, Suppl. 1)

    2000  

    Author's details guest ed. Hugh A. Sampson
    Series title Journal of pediatric gastroenterology and nutrition ; 30, Suppl. 1
    Collection
    Language English
    Size S. S1 - S96 : graph. Darst.
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT011205928
    Database Catalogue ZB MED Medicine, Health

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    Zs A 1728 -30,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  5. Article ; Online: A Historical Perspective on the Substantial Progress in Understanding Eosinophilic Gastrointestinal Disease.

    Davis, Carla M / Sampson, Hugh A

    The journal of allergy and clinical immunology. In practice

    2021  Volume 9, Issue 9, Page(s) 3288–3289

    MeSH term(s) Enteritis ; Eosinophilia/diagnosis ; Gastritis/diagnosis ; Humans
    Language English
    Publishing date 2021-09-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2021.07.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  6. Article ; Online: Safety and efficacy of epicutaneous immunotherapy with DBV712 (peanut patch) in peanut allergy.

    Dupont, Christophe / Burks, A Wesley / Fleischer, David M / Bee, Katharine J / Chainani, Sarita / Sampson, Hugh A

    Expert review of clinical immunology

    2024  , Page(s) 1–11

    Abstract: Introduction: DBV712 250 µg (also referred to as Viaskin Peanut or peanut patch; Viaskin is a trademark of DBV Technologies) is an innovative approach to epicutaneous immunotherapy (EPIT). The patch-based technology system facilitates peanut protein ( ... ...

    Abstract Introduction: DBV712 250 µg (also referred to as Viaskin Peanut or peanut patch; Viaskin is a trademark of DBV Technologies) is an innovative approach to epicutaneous immunotherapy (EPIT). The patch-based technology system facilitates peanut protein (allergen) absorption into the intact non-vascularized epidermis to promote desensitization to peanut while limiting systemic allergen exposure.
    Areas covered: Efficacy and safety in children have been evaluated in four completed phase 3 studies. Overall, the results from these studies have demonstrated the peanut patch to be superior in desensitization compared with placebo and safe for daily use over multiple years.
    Expert opinion: These findings, as well as supportive evidence from phase 2 studies, confirm the potential for an effective treatment of peanut allergy in children. The purpose of this review is to summarize the safety and efficacy of the peanut patch in the treatment of peanut allergy.
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2024.2315221
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Who are the potential patients for omalizumab for food allergy?

    Sampson, Hugh A / Bird, J Andrew / Fleischer, David / Shreffler, Wayne G / Spergel, Jonathan M

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2024  

    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2024.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Sorghum- and millet-induced anaphylaxis: A case report.

    Fritz, Robert P / Grishina, Galina / McMorris, Marc S / Sampson, Hugh A

    The journal of allergy and clinical immunology. In practice

    2024  

    Language English
    Publishing date 2024-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2024.03.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Food allergy: Past, present and future.

    Sampson, Hugh A

    Allergology international : official journal of the Japanese Society of Allergology

    2016  Volume 65, Issue 4, Page(s) 363–369

    Abstract: Hippocrates is often credited with first recognizing that food could be responsible for adverse symptoms and even death in some individuals, but it was not until the seminal observations by Prausnitz that the investigation of food allergy was viewed on a ...

    Abstract Hippocrates is often credited with first recognizing that food could be responsible for adverse symptoms and even death in some individuals, but it was not until the seminal observations by Prausnitz that the investigation of food allergy was viewed on a more scientific basis. In the first half of the 20th century, there were periodic reports in the medical literature describing various food allergic reactions. In the mid- to late- 1970's, the studies of Charles May and colleagues began to penetrate the medical world's skepticism about the relevance of food allergy and how to diagnose it, since standard skin testing was known to correlate poorly with clinical symptoms. With May's introduction of the double-blind placebo-controlled oral food challenge, the study of food allergy became evidence-based and exponential strides have been made over the past four decades in the study of basic immunopathogenic mechanisms and natural history, and the diagnosis and management of food allergies. Today IgE- and non-IgE-mediated food allergic disorders are well characterized and efforts to treat these allergies by various immunotherapeutic strategies are well under way.
    MeSH term(s) Food Hypersensitivity/diagnosis ; Food Hypersensitivity/epidemiology ; Food Hypersensitivity/immunology ; Food Hypersensitivity/therapy ; Humans
    Language English
    Publishing date 2016-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1336498-4
    ISSN 1440-1592 ; 1323-8930
    ISSN (online) 1440-1592
    ISSN 1323-8930
    DOI 10.1016/j.alit.2016.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Impact of using less objective symptoms to define tolerated dose during food challenges: A data-driven approach.

    Turner, Paul J / Patel, Nandinee / Blumchen, Katharina / Berkes, Stefanie / Sampson, Hugh A / Beyer, Kirsten

    The Journal of allergy and clinical immunology

    2023  Volume 152, Issue 1, Page(s) 145–154

    Abstract: Background: Food challenges (FCs) form the basis for assessing efficacy outcomes in interventional studies of food allergy; however, different studies have used a variety of similar but not identical criteria to define a challenge reaction, including ... ...

    Abstract Background: Food challenges (FCs) form the basis for assessing efficacy outcomes in interventional studies of food allergy; however, different studies have used a variety of similar but not identical criteria to define a challenge reaction, including subjective (nonobjective) symptoms occurring in a single-organ system as dose limiting.
    Objective: Our aim was to undertake a secondary analysis of 4 interventional studies to assess the impact of using less objective criteria to determine challenge-stop on reaction thresholds and their reproducibility.
    Methods: We analyzed individual participant data, including individual participant data meta-analysis, by using 3 different published challenge-stop criteria: (1) PRACTALL consesus criteria; (2) Consortium for Food Allergy Research version 3 (CoFAR v3) with at least 1 moderate- or severe-grade symptom; or (3) CoFAR v3 with at least 2 mild symptoms occurring in different organ systems. Reproducibility of challenge threshold was also assessed in participants undergoing subsequent repeat FCs.
    Results: Four studies, with detailed challenge data from a total of 592 participants, were included. Applying CoFAR v3 definitions for dose-limiting symptoms resulted in an underestimate of reaction thresholds compared with those in PRACTALL (P < .001) that is equivalent to almost a single dosing increment when using a semi-log dosing regimen. Reproducibility was also reduced when applying CoFAR v3 (P < .001 [n = 223]). Using the least conservative interpretation of CoFAR v3 (≥2 mild symptoms occurring in different systems) resulted in a significant overestimate of 15% when assessing oral immunotherapy efficacy. Applying a data-driven minor modification to CoFAR v3 resulted in a new set of challenge-stop criteria with validity similar to that of PRACTALL but one that is simpler to implement and in which significant gastrointestinal discomfort with observable decreased activity remains a dose-limiting symptom.
    Conclusion: The use of less objective symptoms to define challenge-stop compromises the reproducibility of the FC as a tool to assess efficacy outcomes in interventional studies, and potentially overestimates the efficacy of the intervention tested.
    MeSH term(s) Humans ; Peanut Hypersensitivity/diagnosis ; Reproducibility of Results ; Food Hypersensitivity/diagnosis ; Allergens ; Immunotherapy/methods
    Chemical Substances Allergens
    Language English
    Publishing date 2023-01-02
    Publishing country United States
    Document type Meta-Analysis ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2022.12.818
    Database MEDical Literature Analysis and Retrieval System OnLINE

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