LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 435

Search options

  1. Article ; Online: Deep Reinforcement Learning for Robotic Control in High-Dexterity Assembly Tasks

    Leyendecker, Lars / Schmitz, M. / Zhou, H.A. / Samsonov, V. / Rittstieg, M. / Lütticke, D.

    2022  

    Abstract: 381 ... 402 ... For years, the fully-automated robotic assembly has been a highly sought-after technology in large-scale manufacturing. Yet it still struggles to find widespread implementation in industrial environments. Traditional programming has so far ... ...

    Abstract 381

    402

    For years, the fully-automated robotic assembly has been a highly sought-after technology in large-scale manufacturing. Yet it still struggles to find widespread implementation in industrial environments. Traditional programming has so far proven to be insufficient in providing the required flexibility and dexterity to solve complex assembly tasks. Research in robotic control using deep reinforcement learning (DRL) advances quickly, however, the transfer to real-world applications in industrial settings is lagging behind. In this study, we apply DRL for robotic motion control to a multi-body contact automotive assembly task. Our focus lies on optimizing the final performance on the real-world setup. We propose a reward-curriculum learning approach in combination with domain randomization to obtain both force-sensitivity and generalizability of the controller's performance. We train the agent exclusively in simulation and successfully perform the Sim-to-Real transfer. Finally, we evaluate the controller's performance and robustness on an industrial setup and reflect its adherence to the high standards of automotive production.

    16

    3
    Keywords assembly ; automotive assembly ; curriculum learning ; robotic control
    Subject code 629
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: A novel one-step method for targeted multiplication of DNA fragments from the Escherichia coli chromosome mediated by coordinated functioning of λ and φ80 bacteriophage recombination systems.

    Igonina, O / Samsonov, V / Ublinskaya, A / Hook, Ch / Malykh, E / Kozaeva, E / Sycheva, E / Stoynova, N

    Journal of microbiological methods

    2020  Volume 170, Page(s) 105842

    Abstract: A novel technique for targeted stable multiplication of a specific long E. coli chromosome fragment was developed. The method is based on the coordinated functioning of λ and φ80 bacteriophage site-specific recombination and integration systems. In vivo ... ...

    Abstract A novel technique for targeted stable multiplication of a specific long E. coli chromosome fragment was developed. The method is based on the coordinated functioning of λ and φ80 bacteriophage site-specific recombination and integration systems. In vivo cloning and targeted insertion of a chosen chromosomal region is accomplished by a simple one-step experiment. The method does not require PCR amplification of an inserted fragment, which makes it especially convenient for manipulation of long-length DNA. For this purpose, we constructed a pKDAH vector that can perform both λRed recombineering and φ80-integrase-mediated integration. Using this technique, the chromosome region is cloned via λRed recombination and immediately inserted into another chromosome locus by φ80-integrase. The method was effectively used for targeted chromosomal integration of additional copies of an individual gene (alaE), a short-length operon (kbl-tdh) and long-length DNA fragments harboring the E. coli atpIBEFHAGDC or nuoABCEFGHIJKLMN operons (7.5 and 15 kb, respectively), thus confirming the utility of the technique. Moreover, duplication of the target genes with simultaneous modification of the regulatory region was performed.
    MeSH term(s) Amino Acid Transport Systems, Neutral/genetics ; Bacteriophages/genetics ; Base Sequence ; Chromosomes, Bacterial/genetics ; Cloning, Molecular/methods ; DNA, Bacterial/genetics ; DNA, Viral/genetics ; Escherichia coli/genetics ; Escherichia coli Proteins/genetics ; Mutagenesis, Insertional/methods ; Recombination, Genetic
    Chemical Substances AlaE protein, E coli ; Amino Acid Transport Systems, Neutral ; DNA, Bacterial ; DNA, Viral ; Escherichia coli Proteins
    Language English
    Publishing date 2020-01-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 604916-3
    ISSN 1872-8359 ; 0167-7012
    ISSN (online) 1872-8359
    ISSN 0167-7012
    DOI 10.1016/j.mimet.2020.105842
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1849: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: When mechanisms of coalescence and sintering at the nanoscale fundamentally differ: Molecular dynamics study.

    Samsonov, V M / Talyzin, I V / Puytov, V V / Vasilyev, S A / Romanov, A A / Alymov, M I

    The Journal of chemical physics

    2022  Volume 156, Issue 21, Page(s) 214302

    Abstract: Employing classical isothermal molecular dynamics, we simulated coalescence of mesoscopic Au nanodroplets, containing from several thousands to several hundred thousands of atoms, and sintering of mesoscopic solid Au nanoparticles. For our atomistic ... ...

    Abstract Employing classical isothermal molecular dynamics, we simulated coalescence of mesoscopic Au nanodroplets, containing from several thousands to several hundred thousands of atoms, and sintering of mesoscopic solid Au nanoparticles. For our atomistic simulations, we used the embedded atom method. The employed open access program large-scale atomic/molecular massively parallel simulator makes it possible to realize parallel graphical processing unit calculations. We have made a conclusion that the regularities and mechanisms of the nanodroplet coalescence (temperature is higher than the nanoparticle melting temperature) and of the solid nanoparticle sintering differ from each other. We have also concluded that the nanodroplet coalescence may be interpreted as a hydrodynamic phenomenon at the nanoscale whereas sintering of solid nanoparticles is a much more complex phenomenon related to different mechanisms, including collective rearrangements of atoms, the surface diffusion, and other types of diffusion. At the same time, collective rearrangements of atoms relate not only to the solid nanoparticle sintering but also to the nanodroplet coalescence. In general, our molecular dynamics results on sintering of Au nanoparticles consisting of 10 000-30 000 atoms agree with the Ferrando-Minnai kinetic trapping concept that was earlier confirmed in molecular dynamics experiments on Au nanoclusters consisting of about 100 atoms.
    Language English
    Publishing date 2022-06-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0075748
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4' 49/16: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Videolaparoskopiya v ekstrennoi khirurgii redko vstrechayushchikhsya, atipichnykh zabolevanii.

    Samsonov, V T / Ermolov, A S / Gulyaev, A A / Yartsev, P A / Rogal, M M

    Khirurgiia

    2020  , Issue 11, Page(s) 25–31

    Abstract: Objective: To analyze the capabilities of laparoscopy in the diagnosis and treatment of atypical diseases.: Material and methods: Laparoscopy was performed in 5188 patients with established, suspected and unclear diagnosis of acute surgical diseases ... ...

    Title translation Laparoscopy in emergency surgery of rare atypical diseases.
    Abstract Objective: To analyze the capabilities of laparoscopy in the diagnosis and treatment of atypical diseases.
    Material and methods: Laparoscopy was performed in 5188 patients with established, suspected and unclear diagnosis of acute surgical diseases for the period from 2008 to 2018. Rare atypical diseases were diagnosed in 114 (2.2%) patients. These diseases simulated established and suspected clinical diagnoses in 100 (87.7%) cases, and the diagnosis was unclear in 5 (4.4%) cases. In 9 (7.9%) patients, atypical diseases were concomitant. In 7 cases, atypical diseases competed with the underlying disease and required emergency surgery. Conservative treatment was required in 2 cases. Seventy (61.4%) patients with atypical diseases needed emergency surgery, and 44 (38.6%) patients required conservative treatment. Laparoscopic operations were performed in 61 (87.1%) patients including simultaneous procedures in 8 cases and video-assisted interventions in 2 (2.9%) patients. Laparotomy was applied in 7 (10.0%) patients.
    Results: Histological examination confirmed laparoscopic diagnosis in 66 out of 68 specimens. Cells of mucus-forming adenocarcinoma were detected in one resected epiploic appendix, carcinomatosis - in one segment of resected omentum.
    Conclusion: Video-assisted laparoscopy was valuable to establish a diagnosis and determine surgical strategy, detect competing and concomitant diseases, perform operations including simultaneous procedures.
    MeSH term(s) Abdominal Neoplasms/surgery ; Appendix/surgery ; Conservative Treatment ; Emergencies ; Humans ; Laparoscopy ; Laparotomy ; Omentum/surgery ; Rare Diseases/diagnosis ; Rare Diseases/surgery ; Video-Assisted Surgery
    Language Russian
    Publishing date 2020-11-18
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 419230-8
    ISSN 2309-5628 ; 0023-1207
    ISSN (online) 2309-5628
    ISSN 0023-1207
    DOI 10.17116/hirurgia202011125
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 740: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: A novel one-step method for targeted multiplication of DNA fragments from the Escherichia coli chromosome mediated by coordinated functioning of λ and φ80 bacteriophage recombination systems

    Igonina, O / Samsonov, V / Ublinskaya, A / Hook, Ch / Malykh, E / Kozaeva, E / Sycheva, E / Stoynova, N

    Journal of microbiological methods. 2020 Mar., v. 170

    2020  

    Abstract: A novel technique for targeted stable multiplication of a specific long E. coli chromosome fragment was developed. The method is based on the coordinated functioning of λ and φ80 bacteriophage site-specific recombination and integration systems. In vivo ... ...

    Abstract A novel technique for targeted stable multiplication of a specific long E. coli chromosome fragment was developed. The method is based on the coordinated functioning of λ and φ80 bacteriophage site-specific recombination and integration systems. In vivo cloning and targeted insertion of a chosen chromosomal region is accomplished by a simple one-step experiment. The method does not require PCR amplification of an inserted fragment, which makes it especially convenient for manipulation of long-length DNA. For this purpose, we constructed a pKDAH vector that can perform both λRed recombineering and φ80-integrase-mediated integration. Using this technique, the chromosome region is cloned via λRed recombination and immediately inserted into another chromosome locus by φ80-integrase. The method was effectively used for targeted chromosomal integration of additional copies of an individual gene (alaE), a short-length operon (kbl-tdh) and long-length DNA fragments harboring the E. coli atpIBEFHAGDC or nuoABCEFGHIJKLMN operons (7.5 and 15 kb, respectively), thus confirming the utility of the technique. Moreover, duplication of the target genes with simultaneous modification of the regulatory region was performed.
    Keywords DNA ; DNA fragmentation ; Escherichia coli ; bacteriophages ; enzymes ; genetic engineering ; loci ; operon ; polymerase chain reaction ; site-specific recombination
    Language English
    Dates of publication 2020-03
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 604916-3
    ISSN 1872-8359 ; 0167-7012
    ISSN (online) 1872-8359
    ISSN 0167-7012
    DOI 10.1016/j.mimet.2020.105842
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1849: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Fermentative Production of Cysteine by Pantoea ananatis.

    Takumi, Kazuhiro / Ziyatdinov, Mikhail Kharisovich / Samsonov, Viktor / Nonaka, Gen

    Applied and environmental microbiology

    2017  Volume 83, Issue 5

    Abstract: Cysteine is a commercially important amino acid; however, it lacks an efficient fermentative production method. Due to its cytotoxicity, intracellular cysteine levels are stringently controlled via several regulatory modes. Managing its toxic effects as ... ...

    Abstract Cysteine is a commercially important amino acid; however, it lacks an efficient fermentative production method. Due to its cytotoxicity, intracellular cysteine levels are stringently controlled via several regulatory modes. Managing its toxic effects as well as understanding and deregulating the complexities of regulation are crucial for establishing the fermentative production of cysteine. The regulatory modes include feedback inhibition of key metabolic enzymes, degradation, efflux pumps, and the transcriptional regulation of biosynthetic genes by a master cysteine regulator, CysB. These processes have been extensively studied using
    MeSH term(s) Amino Acids/biosynthesis ; Amino Acids/genetics ; Bacterial Proteins/genetics ; Biotechnology/methods ; Cystathionine gamma-Lyase/metabolism ; Cysteine/biosynthesis ; Cysteine/genetics ; Cysteine/pharmacology ; Down-Regulation ; Drug Resistance, Bacterial ; Escherichia coli/genetics ; Fermentation ; Gene Expression Regulation, Bacterial ; Genetic Engineering/methods ; Metabolic Networks and Pathways/genetics ; Pantoea/enzymology ; Pantoea/genetics ; Pantoea/metabolism ; Sequence Deletion
    Chemical Substances Amino Acids ; Bacterial Proteins ; CcdA protein, Bacteria ; CysB protein, Bacteria ; Cystathionine gamma-Lyase (EC 4.4.1.1) ; Cysteine (K848JZ4886)
    Language English
    Publishing date 2017-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 223011-2
    ISSN 1098-5336 ; 0099-2240
    ISSN (online) 1098-5336
    ISSN 0099-2240
    DOI 10.1128/AEM.02502-16
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 201: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book ; Conference proceedings: Nauka i innovacii XXI veka

    Samsonov, V. P

    materialy VII okružnoj konferencii molodych učenych, Surgut, 23 - 24 nojabrja 2006 goda

    2007  

    Institution Surgutskij Gosudarstvennyj Universitet
    Event/congress Okružnaja Konferencija Molodych Učenych Nauka i Innovacii XXI Veka (7, 2006.11.23-24, Surgut)
    Author's details Surgutskij Gosudarstvennyj Universitet Chanty-Mansijskogo Avtonomnogo Okruga - Jugry ... [V. P. Samsonov (otv. red.)]
    Language Russian
    Publisher Izdat. SurGU
    Publishing place Surgut
    Document type Book ; Conference proceedings
    Note In kyrill. Schr.
    ISBN 5895452299 ; 9785895452295
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book ; Conference proceedings: Nauka i innovacii XXI veka

    Samsonov, V. P

    : materialy VII okružnoj konferencii molodych učenych, Surgut, 23 - 24 nojabrja 2006 goda

    2007  

    Institution Surgutskij Gosudarstvennyj Universitet
    Event/congress Okružnaja Konferencija Molodych Učenych Nauka i Innovacii XXI Veka (7, 2006.11.23-24, Surgut)
    Author's details Surgutskij Gosudarstvennyj Universitet Chanty-Mansijskogo Avtonomnogo Okruga - Jugry .̤ [V. P. Samsonov (otv. red.)]
    Language Russian
    Size 259 S., graph. Darst.
    Publisher Izdat. SurGU
    Publishing place Surgut
    Document type Book ; Conference proceedings
    ISBN 5895452310 ; 9785895452318
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article: Production of asphaltite-containing road bitumens

    Samsonov, V. V

    Chemistry and technology of fuels and oils. 2008 Nov., v. 44, no. 6

    2008  

    Language English
    Dates of publication 2008-11
    Size p. 393-397.
    Publisher Springer US
    Publishing place Boston
    Document type Article
    ZDB-ID 2037125-1
    ISSN 1573-8310 ; 0009-3092
    ISSN (online) 1573-8310
    ISSN 0009-3092
    DOI 10.1007/s10553-009-0082-1
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Videolaparoskopiya v ekstrennoi khirurgii organov bryushnoi polosti.

    Samsonov, V T / Ermolov, A S / Gulyaev, A A / Yartsev, P A / Levitsky, V D / Rogal, M M

    Khirurgiia

    2019  , Issue 9, Page(s) 32–37

    Abstract: Objective: To evaluate the possibilities of laparoscopy in the diagnosis and treatment of acute abdominal surgical diseases.: Material and methods: A retrospective analysis of laparoscopic procedures in 4655 patients with confirmed or suspected acute ...

    Title translation Laparoscopy in emergency abdominal surgery.
    Abstract Objective: To evaluate the possibilities of laparoscopy in the diagnosis and treatment of acute abdominal surgical diseases.
    Material and methods: A retrospective analysis of laparoscopic procedures in 4655 patients with confirmed or suspected acute abdominal surgical diseases for the period 2008-2017 was performed. Laparoscopy was applied to confirm or to determine unclear diagnosis.
    Results: Diagnosis was established and confirmed in 4526 (97.2%) patients. Advisability of laparoscopic surgery was confirmed in 3091 (68.3%) patients, laparotomy - in 491 (10.8%) patients. Surgical treatment was not required in 944 (20.9%) patients. Laparoscopic procedures were performed in 3050 (98.7%) patients, 41 (1.3%) patients required conversion to laparotomy. Laparoscopic approach failed to define diagnosis in 129 (2.8%) patients that required conversion to diagnostic laparotomy.
    Conclusion: Laparoscopic was valuable to establish the diagnosis and determine surgical strategy, diagnose concomitant diseases, perform operations including simultaneous ones.
    MeSH term(s) Abdomen/surgery ; Abdomen, Acute/diagnosis ; Abdomen, Acute/surgery ; Acute Disease ; Conversion to Open Surgery ; Emergencies ; Humans ; Laparoscopy ; Laparotomy ; Retrospective Studies
    Language Russian
    Publishing date 2019-09-17
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 419230-8
    ISSN 2309-5628 ; 0023-1207
    ISSN (online) 2309-5628
    ISSN 0023-1207
    DOI 10.17116/hirurgia201909132
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 740: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top