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  1. Article: Impact of ergot-contaminated feed on yellow mealworm larvae performance and diet preference

    Ochoa-Sanabria, C. / Duhra, D. / Newkirk, R. / Buchanan, F. / Beaulieu, D.

    Journal of insects as food and feed. 2022 June 5, v. 8, no. 6

    2022  

    Abstract: This study aimed to determine if ergot alkaloids (EA) would accumulate in yellow mealworm larvae (YML, Tenebrio molitor) when present in their diets and investigate effects on production and survival. Larvae were reared on one of four diets: a control, ... ...

    Abstract This study aimed to determine if ergot alkaloids (EA) would accumulate in yellow mealworm larvae (YML, Tenebrio molitor) when present in their diets and investigate effects on production and survival. Larvae were reared on one of four diets: a control, low, medium, and high containing 63, 3,863, 8,471 and 15,316 μg/kg total EA, respectively. Each diet had five replicates with 150 YML per replicate totalling 3,000 for the 21-day trial. Initial and final weights of the feed and larvae were collected. Ergot alkaloid concentrations in YML at d 21 were 32.6, 94.0 and 155.5 μg/kg in the low, medium, and high treatments respectively, with none detected in those fed the control diet. The frass from YML fed the control, low, medium and high diets contained 18, 364, 1,094, and 1,424 μg/kg total EA, respectively. Feed intake was reduced in larvae fed the low, medium and high treatments relative to the control at 23.3-24.9 g/21 d compared to 30.1 g in the control (P=0.02). Feed-to-gain ratios, average daily gain, and final body weights did not differ among treatments (P>0.05). The larvae did not display any preference for diets when allowed to choose between the four diets (P>0.05). Larvae accumulated only low levels of EA from their diets and although feed intake was depressed, growth was maintained. Further research is required to determine the safety of yellow mealworm reared on EA-contaminated diets.
    Keywords Tenebrio molitor ; average daily gain ; diet ; ergot ; ergot alkaloids ; feed intake ; food choices ; frass
    Language English
    Dates of publication 2022-0605
    Size p. 673-679.
    Publishing place Wageningen Academic Publishers
    Document type Article
    ISSN 2352-4588
    DOI 10.3920/JIFF2021.0107
    Database NAL-Catalogue (AGRICOLA)

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  2. Book: Puerto Rican labor history, 1898-1934

    Sanabria, Carlos

    revolutionary ideals and reformist politics

    2018  

    Abstract: He dire conditions of the working class -- Visions of a better future -- Dramatizing revolutionary ideals -- Reformist politics -- The influence of the American Federation of Labor -- ... ...

    Author's details Carlos Sanabria
    Abstract He dire conditions of the working class -- Visions of a better future -- Dramatizing revolutionary ideals -- Reformist politics -- The influence of the American Federation of Labor -- Conclusion
    Keywords Labor movement/History ; Labor unions/History ; Working class/History ; Arbeiterbewegung ; Gewerkschaftsbewegung ; Wirtschaftsgeschichte ; Puerto Rico
    Language English
    Size xiii, 147 pages
    Publisher Lexington Books
    Publishing place Lanham, Maryland
    Document type Book
    Note Includes bibliographical references and index
    ISBN 9781498537834 ; 9781498537841 ; 1498537839 ; 1498537847
    Database ECONomics Information System

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  3. Article ; Online: Early life corticosteroid overexposure: Epigenetic and fetal origins of adult diseases.

    Briceño-Pérez, Carlos / Briceño-Sanabria, Liliana / Briceño-Sanabria, Carlos / Reyna-Villasmil, Eduardo

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2023  Volume 164, Issue 1, Page(s) 40–46

    Abstract: The relationship between events occurring during intrauterine development and later-life predisposition to long-term disease, has been described. The fetus responds to excess intrauterine exposure to high levels of corticosteroids, modifying their ... ...

    Abstract The relationship between events occurring during intrauterine development and later-life predisposition to long-term disease, has been described. The fetus responds to excess intrauterine exposure to high levels of corticosteroids, modifying their physiological development and stopping their growth. Fetal exposure to elevated levels of either endogenous (alterations in fetal hypothalamic-pituitary-adrenal axis) or synthetic corticosteroids, is one model of early-life adversity; to developing adult disease. At the molecular level, there are transcriptional changes in metabolic and growth pathways. Epigenetic mechanisms participate in transgenerational inheritance, not genomic. Exposures that change 11β-hydroxysteroid dehydrogenase type 2 enzyme methylation status in the placenta can result in transcriptional repression of the gene, causing the fetus to be exposed to higher levels of cortisol. More precise diagnosis and management of antenatal corticosteroids for preterm birth, would potentially decrease the risk of long-term adverse outcomes. More studies are needed to understand the potential roles of factors to alter fetal corticosteroid exposure. Long-term infant follow-up is required to determine whether methylation changes in placenta may represent useful biomarkers of later disease risk. This review, summarize recent advances in the programming of fetal effects of corticosteroid exposure, the role of corticosteroids in epigenetic gene regulation of placental 11β-hydroxysteroid dehydrogenase type 2 enzyme expression and transgenerational effects.
    MeSH term(s) Adult ; Pregnancy ; Female ; Infant, Newborn ; Humans ; Placenta/metabolism ; 11-beta-Hydroxysteroid Dehydrogenase Type 2/genetics ; 11-beta-Hydroxysteroid Dehydrogenase Type 2/metabolism ; 11-beta-Hydroxysteroid Dehydrogenase Type 2/pharmacology ; Hypothalamo-Hypophyseal System/physiology ; Pituitary-Adrenal System/physiology ; Premature Birth/chemically induced ; Fetus ; Glucocorticoids/adverse effects ; Epigenesis, Genetic ; Fetal Development/physiology
    Chemical Substances 11-beta-Hydroxysteroid Dehydrogenase Type 2 (EC 1.1.1.146) ; Glucocorticoids
    Language English
    Publishing date 2023-06-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.14914
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 355: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 183: Show issues

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  4. Article: Do morphological traits of ground-dwelling ants respond to land use changes in a neotropical landscape?

    Sanabria, Catalina / Barot, Sébastien / Fonte, Steven J. / Dubs, Florence

    Elsevier B.V. Geoderma. 2022 July 15, v. 418

    2022  

    Abstract: Analyzing the impacts of agricultural activities on biodiversity requires a full knowledge of the ecology of the studied species. Using a trait-based approach may improve our ability to understand land use impacts on less well-studied species in order to ...

    Abstract Analyzing the impacts of agricultural activities on biodiversity requires a full knowledge of the ecology of the studied species. Using a trait-based approach may improve our ability to understand land use impacts on less well-studied species in order to establish general trends that will facilitate the prediction of these impacts. In this study, we applied a trait-based approach to understand the impact of land use change on ant communities in the Colombian Llanos region. Five common land uses were considered (annual crops, rubber plantations, oil palm plantations, improved pastures and semi-natural savannas) to test whether some morphological traits respond to soil properties and land uses. An RLQ analysis shows a significant common structure between species distribution, environmental factors, and morphological ant traits. This indicates that morphological traits could be used to predict the response of ant communities in different land uses since they respond to environmental characteristics as vegetation complexity, composition and management. Based on the selected morphological ant traits, three groups of land uses were differentiated: grazing-based systems, agroforestry plantations and annual crops. Agroforestry plantations, especially rubber plantations tend to host larger and specialized ant species, while grazing-based systems (i.e. improved pastures) mainly host small and generalist ants, and annual crops host more pigmented ants. These findings suggest that certain morphological traits can reflect the ability of ant species to settle down and survive in a given land use system. Our study shows that improving knowledge about trait-environment associations could be a useful way to better understand how ecological filtering shape neotropical ant communities and how they respond to landscape transformation and land use changes.
    Keywords Elaeis guineensis ; Neotropics ; agroforestry ; biodiversity ; common lands ; geographical distribution ; land use change ; landscapes ; prediction ; rubber
    Language English
    Dates of publication 2022-0715
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 281080-3
    ISSN 1872-6259 ; 0016-7061
    ISSN (online) 1872-6259
    ISSN 0016-7061
    DOI 10.1016/j.geoderma.2022.115841
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    In stock of ZB MED Bonn / Germany

    Z 2363: Show issues

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  5. Article ; Online: Improving the effectiveness of electroconvulsive therapy through the determination of anaesthetic depth. Preliminary results.

    Alcoverro-Fortuny, Òscar / Viñas Usan, Ferran / Elena Sanabria, Carmen / Rojo Rodes, José Emilio

    Revista de psiquiatria y salud mental

    2022  Volume 15, Issue 2, Page(s) 151–153

    MeSH term(s) Anesthetics ; Electroconvulsive Therapy/methods ; Humans
    Chemical Substances Anesthetics
    Language English
    Publishing date 2022-07-02
    Publishing country Spain
    Document type Letter
    ISSN 2173-5050
    ISSN (online) 2173-5050
    DOI 10.1016/j.rpsmen.2021.07.004
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  6. Article ; Online: Detecting unexpected growths in health technologies expenditures: the case of MIPRES in Colombia.

    Espinosa, Oscar / Bejarano, Valeria / Sanabria, Cristian / Rodríguez, Jhonathan / Basto, Sergio / Rodríguez-Lesmes, Paul / Robayo, Adriana

    BMC health services research

    2023  Volume 23, Issue 1, Page(s) 1153

    Abstract: We developed an algorithm to explore unexpected growth in the usage and costs of health technologies. We exploit data from the expenditures on technologies funded by the Colombian government under the compulsory insurance system, where all prescriptions ... ...

    Abstract We developed an algorithm to explore unexpected growth in the usage and costs of health technologies. We exploit data from the expenditures on technologies funded by the Colombian government under the compulsory insurance system, where all prescriptions for technologies not included in an explicit list must be registered in a centralized information system, covering the period from 2017 to 2022. The algorithm consists of two steps: an outlier detection method based on the density of the expenditures for selecting a first set of technologies to consider (39 technologies out of 106,957), and two anomaly detection models for time series to determine which insurance companies, health providers, and regions have the most notorious increases. We have found that most medicines associated with atypical behavior and significant monetary growth could be linked to the use of recently introduced drugs in the market. These drugs have valid patents and very specific clinical indications, often involving high-cost pharmacological treatments. The most relevant case is the Burosumab, approved in 2018 to treat a rare genetic disorder affecting skeletal growth. Secondly, there is clear evidence of anomalous increasing trend evolutions in the identified enteral nutritional support supplements or Food for Special Medical Purposes. The health system did not purchase these products before July 2021, but in 2022 they represented more than 500,000 USD per month.
    MeSH term(s) Humans ; Health Expenditures ; Colombia ; Rare Diseases
    Language English
    Publishing date 2023-10-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-023-10155-w
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  7. Article ; Online: Preliminary clinical pharmacokinetic evaluation of bemotrizinol - A new sunscreen active ingredient being considered for inclusion under FDA's over-the-counter (OTC) sunscreen monograph.

    D'Ruiz, Carl D / Plautz, James R / Schuetz, Rolf / Sanabria, Carlos / Hammonds, Jody / Erato, Cassandra / Klock, Jochen / Vollhardt, Juergen / Mesaros, Szilvia

    Regulatory toxicology and pharmacology : RTP

    2023  Volume 139, Page(s) 105344

    Abstract: Protection against sunburn, skin damage and the carcinogenic effects of ultraviolet light are the primary health benefits associated with UV filters used in topical sunscreen drug products. Countries such as Europe have 30+ UV filters approved for ... ...

    Abstract Protection against sunburn, skin damage and the carcinogenic effects of ultraviolet light are the primary health benefits associated with UV filters used in topical sunscreen drug products. Countries such as Europe have 30+ UV filters approved for sunscreen products while the US has about 10, greatly reducing the options to provide diverse, effective sun protection products. Bemotrizinol (BEMT) is the first new sunscreen active ingredient to be evaluated for inclusion in the Over-The-Counter (OTC) sunscreen monograph using FDA's new Generally Recognized as Safe and Effective (GRASE) testing guidelines. An in vitro skin permeation test (IVPT) and clinical pilot pharmacokinetic Maximum Usage Trial (MUsT) were completed to support the GRASE determination for 6% BEMT. IVPT results indicated an oil +10% ethanol as the model sunscreen intervention for the pilot MUsT. The open-label trial revealed: BEMT concentrations rarely exceeded FDA's defined threshold (0.5 ng/mL) in plasma; no evidence for BEMT accumulation or steady-state concentrations above threshold; only one moderate and few mild treatment emergent adverse events (TEAEs). Therefore, maximal topical applications of 6% BEMT in a model sunscreen formulation did not contribute to meaningful systemic exposure. These results support the safety of BEMT 6% for human sunscreen use.
    MeSH term(s) Humans ; Sunscreening Agents ; Sunburn/prevention & control ; Phenols ; Triazines ; Ultraviolet Rays/adverse effects
    Chemical Substances Sunscreening Agents ; bis-ethylhexyloxyphenol methoxyphenyl triazine (PWZ1720CBH) ; Phenols ; Triazines
    Language English
    Publishing date 2023-02-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 604672-1
    ISSN 1096-0295 ; 0273-2300
    ISSN (online) 1096-0295
    ISSN 0273-2300
    DOI 10.1016/j.yrtph.2023.105344
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1711: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Predictive models for health outcomes due to SARS-CoV-2, including the effect of vaccination: a systematic review.

    Espinosa, Oscar / Mora, Laura / Sanabria, Cristian / Ramos, Antonio / Rincón, Duván / Bejarano, Valeria / Rodríguez, Jhonathan / Barrera, Nicolás / Álvarez-Moreno, Carlos / Cortés, Jorge / Saavedra, Carlos / Robayo, Adriana / Franco, Oscar H

    Systematic reviews

    2024  Volume 13, Issue 1, Page(s) 30

    Abstract: Background: The interaction between modelers and policymakers is becoming more common due to the increase in computing speed seen in recent decades. The recent pandemic caused by the SARS-CoV-2 virus was no exception. Thus, this study aims to identify ... ...

    Abstract Background: The interaction between modelers and policymakers is becoming more common due to the increase in computing speed seen in recent decades. The recent pandemic caused by the SARS-CoV-2 virus was no exception. Thus, this study aims to identify and assess epidemiological mathematical models of SARS-CoV-2 applied to real-world data, including immunization for coronavirus 2019 (COVID-19).
    Methodology: PubMed, JSTOR, medRxiv, LILACS, EconLit, and other databases were searched for studies employing epidemiological mathematical models of SARS-CoV-2 applied to real-world data. We summarized the information qualitatively, and each article included was assessed for bias risk using the Joanna Briggs Institute (JBI) and PROBAST checklist tool. The PROSPERO registration number is CRD42022344542.
    Findings: In total, 5646 articles were retrieved, of which 411 were included. Most of the information was published in 2021. The countries with the highest number of studies were the United States, Canada, China, and the United Kingdom; no studies were found in low-income countries. The SEIR model (susceptible, exposed, infectious, and recovered) was the most frequently used approach, followed by agent-based modeling. Moreover, the most commonly used software were R, Matlab, and Python, with the most recurring health outcomes being death and recovery. According to the JBI assessment, 61.4% of articles were considered to have a low risk of bias.
    Interpretation: The utilization of mathematical models increased following the onset of the SARS-CoV-2 pandemic. Stakeholders have begun to incorporate these analytical tools more extensively into public policy, enabling the construction of various scenarios for public health. This contribution adds value to informed decision-making. Therefore, understanding their advancements, strengths, and limitations is essential.
    MeSH term(s) Humans ; United States ; SARS-CoV-2 ; COVID-19/epidemiology ; COVID-19/prevention & control ; Pandemics/prevention & control ; Vaccination ; Outcome Assessment, Health Care
    Language English
    Publishing date 2024-01-16
    Publishing country England
    Document type Systematic Review ; Journal Article
    ZDB-ID 2662257-9
    ISSN 2046-4053 ; 2046-4053
    ISSN (online) 2046-4053
    ISSN 2046-4053
    DOI 10.1186/s13643-023-02411-1
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  9. Article ; Online: Improving the effectiveness of electroconvulsive therapy through the determination of anesthetic depth. Preliminary results.

    Alcoverro-Fortuny, Òscar / Viñas Usan, Ferran / Elena Sanabria, Carmen / Rojo Rodes, José Emilio

    Revista de psiquiatria y salud mental

    2021  

    Title translation Mejora de la efectividad de la terapia electroconvulsiva mediante la determinación de la profundidad anestésica. Resultados preliminares.
    Language Spanish
    Publishing date 2021-08-27
    Publishing country Spain
    Document type Letter
    ISSN 2173-5050
    ISSN (online) 2173-5050
    DOI 10.1016/j.rpsm.2021.07.006
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  10. Article ; Online: Temperature and strain sensitivities of a groove bonded fiber Bragg grating at room and cryogenic temperatures.

    Huang, Xiyong / Davies, Mike / Moseley, Dominic A / Salazar, Erica E / Sanabria, Charlie / Duke, Owen / Ludbrook, Bart M / Badcock, Rodney A

    Applied optics

    2022  Volume 61, Issue 28, Page(s) 8427–8434

    Abstract: Optical fiber Bragg gratings (FBGs) are well suited for applications as temperature or/and strain sensors in harsh environments, e.g., detecting thermal hot spots in high-temperature superconductor (HTS) fusion energy magnets at cryogenic temperatures ... ...

    Abstract Optical fiber Bragg gratings (FBGs) are well suited for applications as temperature or/and strain sensors in harsh environments, e.g., detecting thermal hot spots in high-temperature superconductor (HTS) fusion energy magnets at cryogenic temperatures and high radiation environments. To maximize the signal-to-noise ratio (SNR) of the FBGs to a hot spot, we propose to have them mounted in V-shaped grooves of HTS' copper former. To investigate the differences between different adhesives on transferring strain and heat in this configuration, five arrays of FBGs are mounted in the V-shaped grooves of a copper dog-bone using Scotch-Weld epoxy, Stycast 2850 FT, Apiezon N, and Loctite 5145 silicone. The copper is cycled through tensile forces in a modified universal tensile tester, subjected to a thermal cycle between 293 K and 77 K, and exposed to heat pulse propagations at 293 K and 80 K. The FBGs that are bonded using Stycast show the highest temperature and strain sensitivities at room and cryogenic temperatures. No major differences in the temperature and strain sensitivities have been found between Ormocer and polyimide coated FBGs. Apiezon N is found to transfer strain consistently well below 245 K, which is comparable with other bonding materials in the temperature range between 77 K and 110 K. The FBGs bonded with the four adhesives in the V-groove configurations are shown to have comparable SNRs to a temperature rise of 20 K at 80 K. This paper emphasizes the importance of maximizing the thermal strain transferred from the host material through the bonding agents to achieve high temperature sensitivity of FBGs.
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.460218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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