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  1. Article ; Online: Society of Biological Psychiatry's 2024 Meeting.

    Arrango, Victoria / Sanacora, Gerard

    Biological psychiatry

    2024  

    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Editorial
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2024.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 720: Show issues Location:
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  2. Book: Synaptic stress and pathogenesis of neuropsychiatric disorders

    Popoli, Maurizio / Diamond, David / Sanacora, Gerard

    2014  

    Author's details Maurizio Popoli ; David Diamond ; Gerard Sanacora ed
    Keywords Neurobehavioral disorders/Pathogenesis ; Synapses/Effect of stress on
    Subject code 616.80471
    Language English
    Size XIV, 355 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018404358
    ISBN 978-1-4939-1055-7 ; 9781493910564 ; 1-4939-1055-8 ; 1493910566
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2014 A 3695 available for loan (reading room) Lesesaal EG

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  3. Article ; Online: Is This Where We Stand After Decades of Research to Develop More Personalized Treatments for Depression?

    Sanacora, Gerard

    JAMA psychiatry

    2020  Volume 77, Issue 6, Page(s) E560–E561

    MeSH term(s) Antidepressive Agents/therapeutic use ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/drug therapy ; Humans ; Precision Medicine/methods
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2020-02-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 2701203-7
    ISSN 2168-6238 ; 2168-622X
    ISSN (online) 2168-6238
    ISSN 2168-622X
    DOI 10.1001/jamapsychiatry.2019.4764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Caution Against Overinterpreting Opiate Receptor Stimulation as Mediating Antidepressant Effects of Ketamine.

    Sanacora, Gerard

    The American journal of psychiatry

    2019  Volume 176, Issue 3, Page(s) 249

    MeSH term(s) Antidepressive Agents ; Depression ; Ketamine ; Narcotic Antagonists ; Receptors, Opioid
    Chemical Substances Antidepressive Agents ; Narcotic Antagonists ; Receptors, Opioid ; Ketamine (690G0D6V8H)
    Language English
    Publishing date 2019-02-28
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.2018.18091061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Rapidly Shifting Ketamine Landscape in the US.

    Wilkinson, Samuel T / Palamar, Joseph J / Sanacora, Gerard

    JAMA psychiatry

    2024  Volume 81, Issue 3, Page(s) 221–222

    MeSH term(s) Humans ; Ketamine/pharmacology ; Ketamine/therapeutic use ; Substance-Related Disorders ; Illicit Drugs
    Chemical Substances Ketamine (690G0D6V8H) ; Illicit Drugs
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701203-7
    ISSN 2168-6238 ; 2168-622X
    ISSN (online) 2168-6238
    ISSN 2168-622X
    DOI 10.1001/jamapsychiatry.2023.4945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hopes and Skepticism for Unraveling the Unique Mechanisms of Ketamine's Rapid Onset Antidepressant Actions in Rodent Models.

    Sanacora, Gerard

    Biological psychiatry

    2018  Volume 84, Issue 1, Page(s) 7–8

    MeSH term(s) Animals ; Antidepressive Agents ; Calcium ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 ; Elongation Factor 2 Kinase ; Ketamine ; Rodentia
    Chemical Substances Antidepressive Agents ; Ketamine (690G0D6V8H) ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 (EC 2.7.11.17) ; Elongation Factor 2 Kinase (EC 2.7.11.20) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2018-07-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2018.05.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: At-home ketamine; still a lot to learn.

    Wilkinson, Samuel T / Sanacora, Gerard

    Journal of affective disorders

    2022  Volume 318, Page(s) 150–151

    MeSH term(s) Humans ; Ketamine/adverse effects ; Learning
    Chemical Substances Ketamine (690G0D6V8H)
    Language English
    Publishing date 2022-09-05
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2022.08.090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1485: Show issues Location:
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  8. Article ; Online: Ketamine for the Treatment of Depression-Reply.

    Sanacora, Gerard

    JAMA psychiatry

    2017  Volume 74, Issue 9, Page(s) 971–972

    MeSH term(s) Consensus ; Depression ; Depressive Disorder, Major ; Humans ; Ketamine ; Mood Disorders
    Chemical Substances Ketamine (690G0D6V8H)
    Language English
    Publishing date 2017-07-11
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701203-7
    ISSN 2168-6238 ; 2168-622X
    ISSN (online) 2168-6238
    ISSN 2168-622X
    DOI 10.1001/jamapsychiatry.2017.1776
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  9. Article ; Online: The Intricate Interaction Between Expectations and Therapeutic Outcomes of Psychedelic Agents.

    Colloca, Luana / Nikayin, Sina / Sanacora, Gerard

    JAMA psychiatry

    2023  Volume 80, Issue 9, Page(s) 867–868

    MeSH term(s) Humans ; Hallucinogens/therapeutic use ; Motivation ; Treatment Outcome
    Chemical Substances Hallucinogens
    Language English
    Publishing date 2023-07-05
    Publishing country United States
    Document type Editorial
    ZDB-ID 2701203-7
    ISSN 2168-6238 ; 2168-622X
    ISSN (online) 2168-6238
    ISSN 2168-622X
    DOI 10.1001/jamapsychiatry.2023.1412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Evaluating the Role of Ketamine/Esketamine in the Management of Major Depressive Disorder with Suicide Risk.

    Nikayin, Sina / Sanacora, Gerard

    CNS drugs

    2021  Volume 35, Issue 10, Page(s) 1069–1079

    Abstract: Nearly 5% of individuals in the USA had serious thoughts of suicide in 2019 and over 30% of individuals suffering with major depressive disorder reported suicidal ideation with 2 million of those reporting suicidal ideation with some level of intent. ... ...

    Abstract Nearly 5% of individuals in the USA had serious thoughts of suicide in 2019 and over 30% of individuals suffering with major depressive disorder reported suicidal ideation with 2 million of those reporting suicidal ideation with some level of intent. However, options to treat depressed individuals considered at imminent risk of suicide remain limited. Until the recent approval of esketamine in the treatment of patients with major depressive disorder with serious suicidal thoughts or actions, no medications had been specifically evaluated for use in this population in the acute setting. This review discusses the history and the current understanding of the role of ketamine and esketamine in depression and suicidal ideation and behavior. It covers some of the pivotal studies in this field and provides a summary of their major findings. The trials of esketamine in patients with major depressive disorder with active suicidal ideation or behavior are the first large-scale trials in patients considered at imminent risk of suicide. As such, the design of these studies is by definition novel, a fact that complicates the interpretation of the data and assessment of the true clinical meaningfulness of the findings. Despite this, the findings in toto draw a consistent picture of benefits that appears to outweigh the potential risks of the treatment. The studies also serve to highlight the complexities and limitations associated with clinical trials aiming to test the ability of novel therapeutics to reduce the burden and risks in patients with suicide ideation and behavior.
    MeSH term(s) Antidepressive Agents/therapeutic use ; Clinical Trials, Phase III as Topic/methods ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/drug therapy ; Depressive Disorder, Major/psychology ; Disease Management ; Humans ; Ketamine/therapeutic use ; Risk Assessment/methods ; Suicidal Ideation
    Chemical Substances Antidepressive Agents ; Esketamine (50LFG02TXD) ; Ketamine (690G0D6V8H)
    Language English
    Publishing date 2021-09-07
    Publishing country New Zealand
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1203800-3
    ISSN 1179-1934 ; 1172-7047
    ISSN (online) 1179-1934
    ISSN 1172-7047
    DOI 10.1007/s40263-021-00851-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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