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  1. Article ; Online: Functional differences between Andean oak (Quercus humboldtii Bonpl.) populations: The importance of intraspecific variation.

    Bonilla, Diana / Castañeda-León, Valentina / Corrales, Adriana / Aldana, Ana M / Cárdenas, Julieth V / Sanchez, Adriana

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0299645

    Abstract: Monodominant tree communities can have phenotypic trait variation (intraspecific variation) as extreme as the trait variation across a forest with higher species diversity. An example of such forests is those composed of Quercus, an important genus of ... ...

    Abstract Monodominant tree communities can have phenotypic trait variation (intraspecific variation) as extreme as the trait variation across a forest with higher species diversity. An example of such forests is those composed of Quercus, an important genus of woody angiosperms in the montane neotropical forest. The Andean oak, or Quercus humboldtii Bonpl., is the sole member of this genus in South America and a characteristic component of montane ecosystems. Although there are several studies on the ecology and genetic structure of this species, there are few studies on the functional trait diversity among populations. Understanding functional traits can improve our comprehension of how organisms respond to various environmental conditions. In this study, we aimed to evaluate differences in six functional traits in individuals of the Andean oak, in two ontogenetic stages (juveniles and adults) from three populations with contrasting environmental conditions. Additionally, using T-statistics, we assessed the impact of external filters (e.g., climate, resource availability, large-scale biotic interactions) on population assembly. We found a remarkable level of functional differentiation among Andean oak forests, with all traits differing between populations and five traits differing between ontogenetic stages. External filters had a stronger influence in populations with more extreme environmental conditions. These findings emphasize the dynamic and context-dependent nature of functional traits in this species. However, given the limited exploration of functional diversity in Andean oak populations, further studies are needed to inform conservation efforts.
    MeSH term(s) Humans ; Ecosystem ; Quercus/genetics ; Forests ; Trees ; Ecology
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0299645
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Fidelity and Promiscuity in an Ant-Plant Mutualism: A Case Study of Triplaris and Pseudomyrmex.

    Sanchez, Adriana

    PloS one

    2015  Volume 10, Issue 12, Page(s) e0143535

    Abstract: The association between the myrmecophyte Triplaris and ants of the genus Pseudomyrmex is an often-reported example of mutualism but no molecular studies have examined this association to date. In this study, the interspecific relationships of Triplaris ... ...

    Abstract The association between the myrmecophyte Triplaris and ants of the genus Pseudomyrmex is an often-reported example of mutualism but no molecular studies have examined this association to date. In this study, the interspecific relationships of Triplaris were reconstructed using five molecular markers (two chloroplast and three nuclear), and the relationships of the associated Pseudomyrmex using two molecular regions (one mitochondrial and one nuclear). A data set including all known collections of plant hosts and resident ants was also compiled. The pattern of distribution of both organisms reveals that there are varying degrees of host specificity; most ants show broader host usage (promiscuous) but one species (P. dendroicus) is faithful to a single species of Triplaris. In most ant-plant interactions, host usage is not specific at the species level and preferences may result from geographical or ecological sorting. The specificity of P. dendroicus could be based on chemical recognition of the host they were raised on.
    MeSH term(s) Animals ; Ants/classification ; Ants/physiology ; Phylogeny ; Polygonaceae/parasitology ; Species Specificity ; Symbiosis/physiology
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0143535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Analysis of commercially available snake antivenoms reveals high contents of endotoxins in some products.

    Solano, Gabriela / Ainsworth, Stuart / Sánchez, Adriana / Villalta, Mauren / Sánchez, Paola / Durán, Gina / Gutiérrez, José María / León, Guillermo

    Toxicon: X

    2024  Volume 21, Page(s) 100187

    Abstract: As injectable therapeutics, snake antivenoms must meet specifications for endotoxin content. ... ...

    Abstract As injectable therapeutics, snake antivenoms must meet specifications for endotoxin content. The
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Journal Article
    ISSN 2590-1710
    ISSN (online) 2590-1710
    DOI 10.1016/j.toxcx.2024.100187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The utility of limited Spanish proficiency in interpreted genetic counseling sessions.

    Waggoner, Rebecca M / Harkavy, Nina / Way, Lorraine / Florido, Michelle E / Sánchez, Adriana / Bergner, Amanda L

    Journal of genetic counseling

    2023  Volume 32, Issue 3, Page(s) 663–673

    Abstract: Professional interpreters are an integral component of healthcare for Spanish-speaking individuals with limited English proficiency (LEP). Research has demonstrated that errors in interpretation are common and can contribute to poor outcomes for Spanish- ... ...

    Abstract Professional interpreters are an integral component of healthcare for Spanish-speaking individuals with limited English proficiency (LEP). Research has demonstrated that errors in interpretation are common and can contribute to poor outcomes for Spanish-speaking clients. Providers with some Spanish proficiency may be able to detect clinically significant interpretation errors, potentially limiting negative clinical outcomes and helping to reduce health disparities for clients with LEP. This study aimed to identify the level of Spanish proficiency necessary for genetic counselors to be able to detect a majority of clinically significant errors made by a professional interpreter during a reproductive genetic counseling session. Practicing genetic counselors and genetic counseling graduate students were surveyed regarding their Spanish language background, experience working with interpreters, and self-rated Spanish proficiency. Participants then watched short video clips from three simulated reproductive genetic counseling sessions conducted with a professional interpreter and were tasked with identifying clinically significant interpretation errors. Survey responses were analyzed from 118 participants who met eligibility criteria. Participants who reported "basic" and "fair" Spanish proficiency detected an average of 36.5% and 67% of clinically significant errors, respectively. Those reporting "good" proficiency or higher detected more than 80% of errors. Overall self-rated Spanish proficiency was positively correlated with years of Spanish language education and individual measures of speaking, listening, and reading proficiency, indicating that self-report may be a reasonable measure of proficiency when the goal is error detection in an interpreted session. Genetic counselors with even minimal Spanish proficiency can detect clinically significant interpretation errors, allowing for the correction of these errors during the session. Genetic counselors with "basic" and "fair" may consider genetic counseling-specific Spanish language classes to increase their proficiency to be able to detect a majority of interpretation errors and thereby improve the quality of care and reduce health disparities for Spanish-speaking clients.
    MeSH term(s) Humans ; Genetic Counseling ; Communication Barriers ; Counseling ; Counselors/psychology ; Limited English Proficiency
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1117799-8
    ISSN 1573-3599 ; 1059-7700
    ISSN (online) 1573-3599
    ISSN 1059-7700
    DOI 10.1002/jgc4.1673
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  5. Article: Precision cytopathology: expanding opportunities for biomarker testing in cytopathology.

    Sanchez, Adriana / Bocklage, Thèrése

    Journal of the American Society of Cytopathology

    2018  Volume 8, Issue 2, Page(s) 95–115

    Abstract: Precision cytopathology refers to therapeutically linked biomarker testing in cytopatology, a dynamically growing area of the discipline. This review describes basic steps to expand precision cytopathology services. Focusing exclusively on solid tumors, ... ...

    Abstract Precision cytopathology refers to therapeutically linked biomarker testing in cytopatology, a dynamically growing area of the discipline. This review describes basic steps to expand precision cytopathology services. Focusing exclusively on solid tumors, the review is divided into four sections: Section 1: Overview of precision pathology- opportunities and challenges; Section 2: Basic steps in establishing or expanding a precision cytopathology laboratory; Section 3: Cytopathology specimens suitable for next generation sequencing platforms; and Section 4: Summary. precision cytopathology continues to rapidly evolve in parallel with expanding targeted therapy options. Biomarker assays (companion diagnostics) comprise a multitude of test types including immunohistochemistry, in situ hybridization and molecular genetic tests such as PCR and next generation sequencing all of which are performable on cytology specimens. Best practices for precision cytopathology will incorporate traditional diagnostic approaches allied with careful specimen triage to enable successful biomarker analysis. Beyond triaging, cytopathologists knowledgeable about molecular test options and capabilities have the opportunity to refine diagnoses, prognoses and predictive information thereby assuming a lead role in precision oncology biomarker testing.
    MeSH term(s) Biomarkers, Tumor ; Cytological Techniques/methods ; Humans ; Laboratories/standards ; Laboratory Personnel/education ; Molecular Targeted Therapy/methods ; Neoplasms/diagnosis ; Neoplasms/pathology ; Pathologists/education ; Precision Medicine/methods ; Sequence Analysis/methods
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2018-12-24
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2213-2945
    ISSN 2213-2945
    DOI 10.1016/j.jasc.2018.12.003
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  6. Article ; Online: Importance of natural cloud regimes to ecophysiology in the alpine species, Caltha leptosepala and Arnica parryi, Snowy Range Mountains, southeast Wyoming, USA.

    Sanchez, Adriana / Hughes, Nicole M / Smith, William K

    Functional plant biology : FPB

    2020  Volume 42, Issue 2, Page(s) 186–197

    Abstract: The south-central Rocky Mountains, USA, are characterised by a dry, continental mesoclimate with typical convective cloud formation during the afternoon. Little is known about the specific influence of such predictable cloud patterns on the microclimate ... ...

    Abstract The south-central Rocky Mountains, USA, are characterised by a dry, continental mesoclimate with typical convective cloud formation during the afternoon. Little is known about the specific influence of such predictable cloud patterns on the microclimate and ecophysiology of associated species. During the summer of 2012, days with afternoon clouds were most common (50% of all days) compared with completely clear (24%) or cloudy days (6.5%). In two representative alpine species, Caltha leptosepala DC. and Arnica parryi A. Gray, fully overcast days reduced mean daily photosynthesis (A) by nearly 50% relative to fully clear days. Mean afternoon A was significantly lower on fully cloudy days relative to days with afternoon clouds only or no clouds in both species. Notably, A did not differ during afternoon cloud days relative to clear afternoons. Afternoon clouds significantly reduced transpiration (E) in C. leptosepala relative to clear days, and both species showed mean reductions in plant water stress (i.e. higher Ψ), though this difference was not significant. Water use efficiency (WUE) (A/E) decreased from morning to afternoon, especially on cloudy days, and the presence of clouds had a positive effect on the light reactions of photosynthesis based on fluorescence measurements (Fv'/Fm'), in both species. Cloudy days were characterised by higher Fv/Fm than afternoon clouds and clear days during both the morning and the afternoon (especially for A. parryi) and recovery to near pre-dawn values for cloudy and afternoon cloud day types, but not clear days. Overall, similar ecophysiological advantages of this typical afternoon cloud pattern was apparent in both species, although their spatial microsite differences related to winter snow accumulation may also play an important role.
    Language English
    Publishing date 2020-06-02
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2071582-1
    ISSN 1445-4416 ; 1445-4408
    ISSN (online) 1445-4416
    ISSN 1445-4408
    DOI 10.1071/FP14096
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  7. Article: Nothingness Is All There Is: An Exploration of Objectless Awareness During Sleep.

    Alcaraz-Sánchez, Adriana / Demšar, Ema / Campillo-Ferrer, Teresa / Torres-Platas, Susana Gabriela

    Frontiers in psychology

    2022  Volume 13, Page(s) 901031

    Abstract: Recent years have seen a heightened focus on the study of minimal forms of awareness during sleep to advance the study of consciousness and understand what makes a state conscious. This focus draws on an increased interest in anecdotical descriptions ... ...

    Abstract Recent years have seen a heightened focus on the study of minimal forms of awareness during sleep to advance the study of consciousness and understand what makes a state conscious. This focus draws on an increased interest in anecdotical descriptions made by classic Indian philosophical traditions about unusual forms of awareness during sleep. For instance, in the so-called state of witnessing-sleep or luminosity sleep, one is said to reach a state that goes beyond ordinary dreaming and abide in a state of just awareness, a state in which one is not aware of anything else other than one's own awareness. Moreover, for these traditions, this state is taken to be the essence or background of consciousness. Reports on such a state opens the door to exciting new lines of research in the study of consciousness, such as inquiry into the so-called objectless awareness during sleep-states of awareness that lack an ordinary object of awareness. In this two-staged research project, we attempted to find the phenomenological blueprints of such forms of awareness during sleep in 18 participants by conducting phenomenological interviews, informed by a novel tool in qualitative research, the micro-phenomenological interview (MPI) method. Following a phenomenological analysis, we isolated a similar phase across 12 reported experiences labeled as "nothingness phase" since it described what participants took to be an experience of "nothingness." This common phase was characterized by minimal sense of self-a bodiless self, yet experienced as being "somewhere"-, the presence of non-modal sensations, relatively pleasant emotions, an absence of visual experience, wide and unfocused attention, and an awareness of the state as it unfolded.
    Language English
    Publishing date 2022-06-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.901031
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  8. Article ; Online: Shaping Pathways to Child Health: A Systematic Review of Street-Scale Interventions in City Streets.

    Ortegon-Sanchez, Adriana / Vaughan, Laura / Christie, Nicola / McEachan, Rosemary R C

    International journal of environmental research and public health

    2022  Volume 19, Issue 9

    Abstract: Street-level built environment factors, for example, walking infrastructure, building density, availability of public transport, and proliferation of fast-food outlets can impact on health by influencing our ability to engage in healthy behaviour. ... ...

    Abstract Street-level built environment factors, for example, walking infrastructure, building density, availability of public transport, and proliferation of fast-food outlets can impact on health by influencing our ability to engage in healthy behaviour. Unhealthy environments are often clustered in deprived areas, thus interventions to improve the built environments may improve health and reduce inequalities. The aim of this review was to identify whether street-level built environment interventions can improve children's health in high income countries. A secondary aim was to describe key built environment elements targeted in interventions and research gaps. A systematic review of published literature was conducted by a multi-disciplinary team. Ten intervention papers were included. Physical activity or play was the only health outcome assessed. Most interventions described temporary changes including closure of streets to traffic (N = 6), which were mainly located in deprived neighbourhoods, or the addition of technology to 'gamify' active travel to school (N = 2). Two studies reported permanent changes to street design. There was limited evidence that closing streets to traffic was associated with increases in activity or play and inconclusive evidence with changes to street design and using technology to gamify active travel. Our ability to draw conclusions was hampered by inadequate study designs. Description of interventions was poor. Rigorous evaluation of built environment interventions remains challenging. We recommend a multi-disciplinary approach to evaluation, explicit reporting of built environment indicators targeted in interventions and offer solutions to others working in this area.
    MeSH term(s) Built Environment ; Child ; Child Health ; Environment Design ; Exercise ; Humans ; Residence Characteristics ; Walking
    Language English
    Publishing date 2022-04-25
    Publishing country Switzerland
    Document type Journal Article ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19095227
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  9. Article ; Online: How to fill the biodiversity data gap: Is it better to invest in fieldwork or curation?

    Vargas, Carlos A / Bottin, Marius / Sarkinen, Tiina / Richardson, James E / Celis, Marcela / Villanueva, Boris / Sanchez, Adriana

    Plant diversity

    2023  Volume 46, Issue 1, Page(s) 39–48

    Abstract: Data gaps and biases are two important issues that affect the quality of biodiversity information and downstream results. Understanding how best to fill existing gaps and account for biases is necessary to improve our current information most effectively. ...

    Abstract Data gaps and biases are two important issues that affect the quality of biodiversity information and downstream results. Understanding how best to fill existing gaps and account for biases is necessary to improve our current information most effectively. Two current main approaches for obtaining and improving data include (1) curation of biological collections, and (2) fieldwork. However, the comparative effectiveness of these approaches in improving biodiversity data remains little explored. We used the Flora de Bogotá project to study the magnitude of change in species richness, spatial coverage, and sample coverage of plant records based on curation versus fieldwork. The process of curation resulted in a decrease in species richness (synonym and error removal), but it significantly increased the number of records per species. Fieldwork contributed to a slight increase in species richness, via accumulation of new records. Additionally, curation led to increases in spatial coverage, species observed by locality, the number of plant records by species, and localities by species compared to fieldwork. Overall, curation was more efficient in producing new information compared to fieldwork, mainly because of the large number of records available in herbaria. We recommend intensive curatorial work as the first step in increasing biodiversity data quality and quantity, to identify bias and gaps at the regional scale that can then be targeted with fieldwork. The stepwise strategy would enable fieldwork to be planned more cost-effectively given the limited resources for biodiversity exploration and characterization.
    Language English
    Publishing date 2023-06-15
    Publishing country China
    Document type Journal Article
    ZDB-ID 2873411-7
    ISSN 2468-2659 ; 2095-0845
    ISSN (online) 2468-2659
    ISSN 2095-0845
    DOI 10.1016/j.pld.2023.06.003
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  10. Article ; Online: Variable thermal plasticity of leaf functional traits in Andean tropical montane forests.

    Cox, Andrew J F / González-Caro, Sebastián / Meir, Patrick / Hartley, Iain P / Restrepo, Zorayda / Villegas, Juan C / Sanchez, Adriana / Mercado, Lina M

    Plant, cell & environment

    2023  Volume 47, Issue 3, Page(s) 731–750

    Abstract: Tropical montane forests (TMFs) are biodiversity hotspots and provide vital ecosystem services, but they are disproportionately vulnerable to climate warming. In the Andes, cold-affiliated species from high elevations are being displaced at the hot end ... ...

    Abstract Tropical montane forests (TMFs) are biodiversity hotspots and provide vital ecosystem services, but they are disproportionately vulnerable to climate warming. In the Andes, cold-affiliated species from high elevations are being displaced at the hot end of their thermal distributions by warm-affiliated species migrating upwards from lower elevations, leading to compositional shifts. Leaf functional traits are strong indicators of plant performance and at the community level have been shown to vary along elevation gradients, reflecting plant adaptations to different environmental niches. However, the plastic response of such traits to relatively rapid temperature change in Andean TMF species remains unknown. We used three common garden plantations within a thermosequence in the Colombian Andes to investigate the warming and cooling responses of key leaf functional traits in eight cold- and warm-affiliated species with variable thermal niches. Cold-affiliated species shifted their foliar nutrient concentrations when exposed to warming, while all other traits did not significantly change; contrastingly, warm-affiliated species were able to adjust structural, nutrient and water-use efficiency traits from acquisitive to conservative strategies in response to cooling. Our findings suggest that cold-affiliated species will struggle to acclimate functional traits to warming, conferring warm-affiliated species a competitive advantage under climate change.
    MeSH term(s) Ecosystem ; Trees/physiology ; Tropical Climate ; Forests ; Plant Leaves/physiology
    Language English
    Publishing date 2023-12-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391893-2
    ISSN 1365-3040 ; 0140-7791
    ISSN (online) 1365-3040
    ISSN 0140-7791
    DOI 10.1111/pce.14778
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