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  1. Article: Periprosthetic joint infections in femoral neck fracture patients treated with hemiarthroplasty - should we use antibiotic-loaded bone cement?

    Crego-Vita, Diana / Aedo-Martín, Daniel / Garcia-Cañas, Rafael / Espigares-Correa, Andrea / Sánchez-Pérez, Coral / Berberich, Christof Ernst

    World journal of orthopedics

    2022  Volume 13, Issue 2, Page(s) 150–159

    Abstract: Background: Hemiarthroplasty is the most common treatment in elderly patients with displaced intra-capsular femoral neck fracture (FNF). Prosthetic joint infection (PJI) is one of the most feared and frequent complications post-surgery because of the ... ...

    Abstract Background: Hemiarthroplasty is the most common treatment in elderly patients with displaced intra-capsular femoral neck fracture (FNF). Prosthetic joint infection (PJI) is one of the most feared and frequent complications post-surgery because of the frail health status of these patients and the need for fast track surgery. Therefore, priorities should lie in effective preventive strategies to mitigate this burden.
    Aim: To determine how much the implementation of the routine use of antibiotic-loaded bone cement (ALBC) as a relatively easy-to-apply amendment to the surgical practice reduces the infection rate in our hemiarthroplasty cohort.
    Methods: We retrospectively assessed all demographic, health status and treatment-related data of our FNF patients undergoing cemented hemiarthroplasty in the period from 2011 to 2017; 241 patients were further analyzed after exclusion of patients with cancer-related sequelae and those who died before the end of the 1-year observation period. The PJI rate as diagnosed on basis of the Musculoskeletal Infection Society (MSIS) criteria 2011 was determined for each included patient and compared in function of the bone cement used for hip stem fixation. Patients were split into a group receiving a plain bone cement in the period from January 2011 to June 2013 (non-ALBC group) and into a group receiving an ALBC in the period July 2013 to December 2017 (ALBC group). Data analysis was performed with statistical software. We further calculated the cost-efficacy of the implementation of routine use of ALBC in the second group balancing the in-hospital infection related treatment costs with the extra costs of use of ALBC.
    Results: In total 241 FNF patients who received cemented hemiarthroplasty in the period from January 2011 to January 2017 were eligible for inclusion in this retrospective study. There were 8 PJI cases identified in the ALBC group among
    Conclusion: Use of ALBC is a potent infection preventive factor in FNF patients receiving cemented hemiarthroplasties. It was further found to be highly cost-effective.
    Language English
    Publishing date 2022-02-18
    Publishing country United States
    Document type Clinical Trial
    ZDB-ID 2649712-8
    ISSN 2218-5836
    ISSN 2218-5836
    DOI 10.5312/wjo.v13.i2.150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Case report of early aseptic loosening of total hip arthroplasty in monostotic paget disease, a diagnostic challenge.

    Crego-Vita, Diana / Aedo-Martín, Daniel / Sánchez-Pérez, Coral

    International journal of surgery case reports

    2016  Volume 24, Page(s) 215–218

    Abstract: Paget's disease of bone is a localised chronic osteopathy which produces bone deformities, bone hypervascularity, structural weakness and altered joint biomechanics. Although radiological diagnosis of Paget's disease of bone is usually straightforward, ... ...

    Abstract Paget's disease of bone is a localised chronic osteopathy which produces bone deformities, bone hypervascularity, structural weakness and altered joint biomechanics. Although radiological diagnosis of Paget's disease of bone is usually straightforward, monostotic cases may potentially raise specific problems which require invasive and expensive procedures such as bone biopsies. The pelvis and upper femur are frequently affected, resulting in disabling hip disease that may require total hip arthroplasty. We report a case of Paget disease of bone in an 84-year-old woman, which was initially identified as avascular necrosis of the hip, reason for which she underwent total hip arthroplasty. During follow up, the patient complained about hip pain and in a few months she was not able to walk because of an early loosening with bone destruction. Radiological and laboratory exams were carried out with normal results except for alkaline phosphatase (AP). After treatment with biphosphonates hip pain relieved but hip reconstruction was not possible. In this paper we present an early aseptic loosening of hip arthroplasty due to monostotic Paget's disease of bone, a rare ethiology of loosening which poses particular diagnostic difficulties prompting an excessive use of excisional biopsies.
    Language English
    Publishing date 2016-05-31
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2016.05.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Overview of fracture liaison services in the UK and Europe: standards, model of care, funding, and challenges.

    Chesser, Timothy J S / Javaid, Muhammad Kassim / Mohsin, Zaineb / Pari, Carlotta / Belluati, Alberto / Contini, Achille / Caiaffa, Vincenzo / Chana-Rodríguez, Francisco / Gómez-Vallejo, Jesus / Sánchez-Pérez, Coral / Dailiana, Zoe H / Stefanou, Nikolaos / Tosounidis, Theodoros / Laurent, Michaël / Putzeys, Guy / Poeze, Martijn / Ponsen, Kees Jan

    OTA international : the open access journal of orthopaedic trauma

    2022  Volume 5, Issue 3 Suppl, Page(s) e198

    Abstract: Fragility fractures represent a growing global problem, including in the United Kingdom and European countries. Reports demonstrate the benefits of national guidance and organized fragility fracture programs through fracture liaison services to deliver ... ...

    Abstract Fragility fractures represent a growing global problem, including in the United Kingdom and European countries. Reports demonstrate the benefits of national guidance and organized fragility fracture programs through fracture liaison services to deliver care to patients who sustain these injuries. The challenge of assembling multidisciplinary teams, providing routine screening of appropriate patients, and monitoring therapies where there is a known compliance problem, remains an obstacle to the success of fragility fracture treatment programs to all. Efforts should continue to introduce and maintain fracture liaison services through coordinated national approaches and advanced systems.
    Language English
    Publishing date 2022-06-09
    Publishing country United States
    Document type Journal Article
    ISSN 2574-2167
    ISSN (online) 2574-2167
    DOI 10.1097/OI9.0000000000000198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ultrasound-guided supra-acetabular pelvic external fixator (US-SA FIX).

    Cuervas-Mons, Manuel / Sánchez-Pérez, Coral / Arnal-Burró, Juan / Vaquero-Martín, Javier / Chana-Rodríguez, Francisco

    Injury

    2019  Volume 50 Suppl 1, Page(s) S24–S29

    Abstract: Background: Between the different options in pelvic external fixation, the supra-acetabular pin placement is considered the best option by many authors. The aim of this study is to describe the surgical technique of the ultrasound-guided supra- ... ...

    Abstract Background: Between the different options in pelvic external fixation, the supra-acetabular pin placement is considered the best option by many authors. The aim of this study is to describe the surgical technique of the ultrasound-guided supra-acetabular pelvic external fixator (US-SA FIX).
    Surgical technique: Description of the steps to perform the US-SA FIX technique.
    Discussion: The supra-acetabular pin placement is considered the best option and it is the most wildly used because it combines three crucial qualities: safety, simplicity, and effectiveness. Notwithstanding, when a severely multiple injured patient arrives at the emergency room we need to perform an emergency external fixation, however trained x-ray technicians or pelvic surgeons are not always present, making it difficult to perform the surgery with the proper intra-operative imaging, increasing the surgical time with potentially serious repercussions, a case scenario where the ultrasound can be a very helpful tool. Ultrasound-guided supra-acetabular pelvic external fixator pin placement is feasible without compromising the reliability of its placement, and the application of this new technique in clinical practice in our centre brings encouraging results.
    MeSH term(s) Acetabulum/diagnostic imaging ; Acetabulum/injuries ; Acetabulum/surgery ; Biomechanical Phenomena ; Bone Nails ; External Fixators ; Fracture Fixation/methods ; Fractures, Bone/diagnostic imaging ; Fractures, Bone/pathology ; Fractures, Bone/surgery ; Humans ; Retrospective Studies ; Ultrasonography, Interventional
    Language English
    Publishing date 2019-04-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2019.03.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Conceptual evolution of 3D printing in orthopedic surgery and traumatology: from "do it yourself" to "point of care manufacturing".

    Calvo-Haro, Jose Antonio / Pascau, Javier / Mediavilla-Santos, Lydia / Sanz-Ruiz, Pablo / Sánchez-Pérez, Coral / Vaquero-Martín, Javier / Perez-Mañanes, Rubén

    BMC musculoskeletal disorders

    2021  Volume 22, Issue 1, Page(s) 360

    Abstract: Background: 3D printing technology in hospitals facilitates production models such as point-of-care manufacturing. Orthopedic Surgery and Traumatology is the specialty that can most benefit from the advantages of these tools. The purpose of this study ... ...

    Abstract Background: 3D printing technology in hospitals facilitates production models such as point-of-care manufacturing. Orthopedic Surgery and Traumatology is the specialty that can most benefit from the advantages of these tools. The purpose of this study is to present the results of the integration of 3D printing technology in a Department of Orthopedic Surgery and Traumatology and to identify the productive model of the point-of-care manufacturing as a paradigm of personalized medicine.
    Methods: Observational, descriptive, retrospective and monocentric study of a total of 623 additive manufacturing processes carried out in a Department of Orthopedic Surgery and Traumatology from November 2015 to March 2020. Variables such as product type, utility, time or materials for manufacture were analyzed.
    Results: The areas of expertise that have performed more processes are Traumatology, Reconstructive and Orthopedic Oncology. Pre-operative planning is their primary use. Working and 3D printing hours, as well as the amount of 3D printing material used, vary according to the type of product or material delivered to perform the process. The most commonly used 3D printing material for manufacturing is polylactic acid, although biocompatible resin has been used to produce surgical guides. In addition, the hospital has worked on the co-design of customized implants with manufacturing companies.
    Conclusions: The integration of 3D printing in a Department of Orthopedic Surgery and Traumatology allows identifying the conceptual evolution from "Do-It-Yourself" to "POC manufacturing".
    MeSH term(s) Humans ; Models, Anatomic ; Orthopedic Procedures ; Point-of-Care Systems ; Printing, Three-Dimensional ; Retrospective Studies ; Traumatology
    Language English
    Publishing date 2021-04-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041355-5
    ISSN 1471-2474 ; 1471-2474
    ISSN (online) 1471-2474
    ISSN 1471-2474
    DOI 10.1186/s12891-021-04224-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Intracapsular hip fractures in the elderly. Do we know what is important?

    Crego-Vita, Diana / Sanchez-Perez, Coral / Gomez-Rico, Jose Adolfo Orellana / de Arriba, Celia Clemente

    Injury

    2017  Volume 48, Issue 3, Page(s) 695–700

    Abstract: Background: Hip fractures in the elderly are a common reason for admission to the department of orthopaedic surgery, this condition asks an important part of health resources and is associated with high levels of co-morbidity and mortality. Many ... ...

    Abstract Background: Hip fractures in the elderly are a common reason for admission to the department of orthopaedic surgery, this condition asks an important part of health resources and is associated with high levels of co-morbidity and mortality. Many improvements have been introduced in the treatment of these patients, preoperative regional analgesia, intensive physical therapy, interdisciplinary care program; but still remain unresolved gaps. The aim of this study is to document the natural history of early versus delayed surgical intervention in elderly patients with hip fractures and to establish the prognostic factors of mortality and walking ability after discharge.
    Methods: A sample of 499 patients admitted in our Institution was prospectively reviewed between February 2008 and February 2013. Preoperatively characteristics and functional data were assessed in relation with time to surgery (focused on mortality and ability to walk at first year).
    Results: The ability to walk and activities of daily living (functional results) were not associated with surgical delays (surgery before 24h from admission, surgery among 24h and 72h from admission and surgery later than 72h). However, ASA class, Parkinson disease and age were significantly associated with poor functional results. In the same way, mortality at 1year was not associated with time to surgery, but ASA class was associated with significant risk factor of 1 year-mortality.
    Conclusions: ASA class, Parkinson disease and age are independent predictor of poor functional outcomes after intracapsular hip fracture. In addition, ASA class is an independent predictor of mortality. Patients with poor functional status before fracture and older than 75 years would benefit from geriatric and rehabilitation intervention immediately after surgery.
    Language English
    Publishing date 2017-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2017.01.022
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  7. Article ; Online: Clinical and radiological outcomes of trabecular metal systems and antiprotrusion cages in acetabular revision surgery with severe defects: a comparative study.

    López-Torres, Irene Isabel / Sanz-Ruíz, Pablo / Sánchez-Pérez, Coral / Andrade-Albarracín, Ricardo / Vaquero, Javier

    International orthopaedics

    2018  Volume 42, Issue 8, Page(s) 1811–1818

    Abstract: Introduction: Acetabular revision surgery poses a challenge due to the increased frequency of severe defects and poor quality of the remaining bone. We compare the clinical and radiological outcomes, complications, and survival of two systems commonly ... ...

    Abstract Introduction: Acetabular revision surgery poses a challenge due to the increased frequency of severe defects and poor quality of the remaining bone. We compare the clinical and radiological outcomes, complications, and survival of two systems commonly used in complex acetabular revisions (AAOS types II, III, and IV): trabecular metal system (TM) and Burch-Schneider antiprotrusion cages (BS).
    Methods: Eighty-four patients underwent acetabular revision surgery with TM or BS in our centre between 2008 and 2014. Comparison was made of demographic and clinical characteristics, satisfaction, radiographic parameters, complications, and survival of the implants. A BS was implanted in 30.9% of the patients, while 69.1% received a TM implant. The mean follow-up was 4.77 years.
    Results: The BS group required a significantly greater number of constrained implants (p = 0.001) and more walking aids (p = 0.04). The mean satisfaction (p = 0.02) and HHS scores at the end of the follow-up were higher in the TM group (p = 0.003). No differences were observed in the incidence of complications, though the only two cases of implant rupture corresponded to the BS group. The overall survival rate was 88.1% after 7.5 years.
    Conclusion: TM implants afforded better clinical outcomes and greater patient satisfaction than antiprotrusion cages in the treatment of severe acetabular defects.
    MeSH term(s) Acetabulum/surgery ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip/adverse effects ; Arthroplasty, Replacement, Hip/instrumentation ; Female ; Hip Prosthesis/adverse effects ; Humans ; Male ; Metals/adverse effects ; Middle Aged ; Patient Satisfaction/statistics & numerical data ; Postoperative Complications/epidemiology ; Prosthesis Design/adverse effects ; Reoperation/adverse effects ; Reoperation/instrumentation ; Reoperation/methods ; Retrospective Studies ; Survival Rate ; Treatment Outcome
    Chemical Substances Metals
    Language English
    Publishing date 2018-02-26
    Publishing country Germany
    Document type Comparative Study ; Journal Article
    ZDB-ID 80384-4
    ISSN 1432-5195 ; 0341-2695
    ISSN (online) 1432-5195
    ISSN 0341-2695
    DOI 10.1007/s00264-018-3801-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: 3D surgical printing for preoperative planning of trabecular augments in acetabular fracture sequel.

    Sánchez-Pérez, Coral / Rodríguez-Lozano, Guillermo / Rojo-Manaute, José / Vaquero-Martín, Javier / Chana-Rodríguez, Francisco

    Injury

    2018  Volume 49 Suppl 2, Page(s) S36–S43

    Abstract: We describe the methodical and possibilities of 3D surgical printing in preoperative planning for a total hip arthroplasty in acetabular deformity after acetabular fractures, showing a case of a 43-year-old with posttraumatic arthritis after both column ... ...

    Abstract We describe the methodical and possibilities of 3D surgical printing in preoperative planning for a total hip arthroplasty in acetabular deformity after acetabular fractures, showing a case of a 43-year-old with posttraumatic arthritis after both column fracture of the left acetabulum that was treated non operatively, supporting the do it yourself mode.
    MeSH term(s) Acetabulum/anatomy & histology ; Acetabulum/diagnostic imaging ; Acetabulum/injuries ; Adult ; Arthroplasty, Replacement, Hip ; Cancellous Bone/pathology ; Conservative Treatment/adverse effects ; Fractures, Bone/diagnostic imaging ; Fractures, Bone/surgery ; Hip Dislocation/diagnostic imaging ; Hip Dislocation/surgery ; Humans ; Male ; Osteoarthritis, Hip/diagnostic imaging ; Osteoarthritis, Hip/etiology ; Osteoarthritis, Hip/surgery ; Printing, Three-Dimensional ; Treatment Outcome
    Language English
    Publishing date 2018-09-15
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2018.07.014
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  9. Article ; Online: International trauma care: initial European approaches during the COVID 19 pandemic.

    Chesser, Tim J S / Handley, Robert / Kloos, Johannes / De Wachter, Gerrit / Putzeys, Guy / Gómez-Vallejo, Jesús / Sánchez-Pérez, Coral / Chana-Rodríguez, Francisco / Raggini, Filippo / Pari, Carlotta / Paderni, Stefania / Contini, Achille / Belluati Md, Alberto / Daskalakis, Ioannis / Sperelakis, Ioannis / Kostakos, Athanasios / Tosounidis, Theodoros H / Halvachizadeh Md, Sascha / Pape Md, Hans-Christoph /
    Bouillon, Bertil / de Bruin, Berend-Jan / Ponsen, Keesjan J

    OTA international : the open access journal of orthopaedic trauma

    2021  Volume 4, Issue 1 Suppl, Page(s) e112

    Abstract: The world was not prepared for the global of pandemic in early 2020 with the arrival of COVID 19. Europe has some of the most developed health care systems in the world and this article explains the initial response to the pandemic from an orthopaedic ... ...

    Abstract The world was not prepared for the global of pandemic in early 2020 with the arrival of COVID 19. Europe has some of the most developed health care systems in the world and this article explains the initial response to the pandemic from an orthopaedic and trauma viewpoint from 8 nations. Italy reported the first cluster in February, which then rapidly spread around the continent, requiring a rapid reorganization of services. The reports highlight how elective surgery was universally stopped, surgical services were reconfigured, and new practices, such as the widespread use of telemedicine, may well become permanent. It also emphasizes how the pandemic has re-educated us on the importance of a consistent and central approach to deal with a global health crisis, and how medical services need to remain flexible and responsive to new ways of working.
    Language English
    Publishing date 2021-03-15
    Publishing country United States
    Document type Journal Article
    ISSN 2574-2167
    ISSN (online) 2574-2167
    DOI 10.1097/OI9.0000000000000112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Intraoperative radiotherapy for extremity soft-tissue sarcomas: can long-term local control be achieved?

    Carbó-Laso, Esther / Sanz-Ruiz, Pablo / Calvo-Haro, José Antonio / Cuervo-Dehesa, Miguel / Pérez-Mañanes, Rubén / Mediavilla-Santos, Lydia / Sánchez-Pérez, Coral / Álvarez-González, Ana / Vaquero-Martín, Javier

    International journal of clinical oncology

    2017  Volume 22, Issue 6, Page(s) 1094–1102

    Abstract: Background: Intraoperative electron-beam radiation therapy (IOERT) during limb-sparing surgery has the advantage of delivering a single high boost dose to sarcoma residues and surgical bed area near to radiosensitive structures with limited toxicity. ... ...

    Abstract Background: Intraoperative electron-beam radiation therapy (IOERT) during limb-sparing surgery has the advantage of delivering a single high boost dose to sarcoma residues and surgical bed area near to radiosensitive structures with limited toxicity. Retrospective studies have suggested that IOERT may improve local control compared to standard radiotherapy and we aimed to demonstrate this theory. Therefore, we performed an observational prospective study to determine (1) if it is possible to achieve high local control by adding IOERT to external-beam radiation therapy (EBRT) in extremity soft-tissue sarcomas (STS), (2) if it is possible to improve long-term survival rates, and (3) if toxicity could be reduced with IOERT MATERIALS AND METHODS: From 1995-2003, 39 patients with extremity STS were treated with IOERT and postoperative radiotherapy. The median follow-up time was 13.2 years (0.7-19). Complications, locoregional control and survival rates were collected.
    Results: Actuarial local control was attained in 32 of 39 patients (82%). Control was achieved in 88% of patients with primary disease and in 50% of those with recurrent tumors (p = 0.01). Local control was shown in 93% of patients with negative margins and in 50% of those with positive margins (p = 0.002). Limb-sparing was achieved in 32 patients (82%). The overall survival rate was 64%. 13% of patients had grade ≥3 acute toxicity, and 12% developed grade ≥3 chronic toxicity.
    Conclusion: IOERT used as a boost to EBRT provides high local control and limb-sparing rates in patients with STS of the extremities, with less toxicity than EBRT alone.
    Language English
    Publishing date 2017-12
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1400227-9
    ISSN 1437-7772 ; 1341-9625
    ISSN (online) 1437-7772
    ISSN 1341-9625
    DOI 10.1007/s10147-017-1162-6
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