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Book ; Online ; E-Book: Urine Tests

Sharp, Victoria J.A. / Antes, Lisa M. / Sanders, M. Lee / Lockwood, Gina M.

A Case-Based Guide to Clinical Evaluation and Application

2020

Abstract: Urine tests are used by a variety of primary care providers and specialists in order to diagnose, monitor and treat patients with various medical conditions. This first-of-its-kind text is a comprehensive clinical guide to the evaluation and application ... ...

Author's details	edited by Victoria J.A. Sharp, Lisa M. Antes, M. Lee Sanders, Gina M. Lockwood
Abstract	Urine tests are used by a variety of primary care providers and specialists in order to diagnose, monitor and treat patients with various medical conditions. This first-of-its-kind text is a comprehensive clinical guide to the evaluation and application of urine tests. Clinical cases are used to highlight important aspects of urine testing. Further evaluation and management are then discussed based on the results of the urine tests. Topics covered include financial considerations, regulations, proper collection, testing methods, dipstick analysis, microscopy as well as cancer and drug screening tests, among others. Each chapter contains specific objectives for focus of study. Pertinent images, algorithms and board style review questions for important topics are also included. Written by nephrologists, urologists, other specialists and primary care physicians, Urine Tests uses a comprehensive approach to the clinical use of both common and uncommon urine testing. Primarily appealing to practicing primary care physicians, this book is also a useful resource for specialists, nurse practitioners, physician assistants, physician fellows, residents and medical students alike. .
Keywords	General practice (Medicine) ; Primary care (Medicine) ; Urology ; General Practice / Family Medicine ; Primary Care Medicine ; Urologia ; Atenció primària
Subject code	616.07566
Language	English
Size	1 online resource (XXI, 389 p. 77 illus., 71 illus. in color.)
Edition	1st ed. 2020.
Publisher	Springer International Publishing ; Imprint: Springer
Publishing place	Cham
Document type	Book ; Online ; E-Book
Note	Includes index.
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	3-030-29138-3 ; 3-030-29137-5 ; 978-3-030-29138-9 ; 978-3-030-29137-2
DOI	10.1007/978-3-030-29138-9
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Hypertensive Emergency.

Suneja, Manish / Sanders, M Lee

The Medical clinics of North America

2017 Volume 101, Issue 3, Page(s) 465–478

Abstract: A rapid and severe increase in blood pressure resulting in new or progressive end-organ damage is defined as hypertensive emergency. Clinicians should effectively use the patient interview, physical examination, and additional testing to differentiate ... ...

Abstract	A rapid and severe increase in blood pressure resulting in new or progressive end-organ damage is defined as hypertensive emergency. Clinicians should effectively use the patient interview, physical examination, and additional testing to differentiate hypertensive emergency from nonemergent hypertension. Patients with evidence or high suspicion for end-organ damage should be expediently referred from the outpatient setting to a higher level of care. Knowledge of appropriate hypertensive emergency management and the ability to initiate this care in the clinic could help reduce patient morbidity in certain situations. Patients presenting with nonemergent hypertension can continue to be safely managed in the clinic.
MeSH term(s)	Blood Pressure ; Blood Pressure Determination ; Blood Volume ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/physiopathology ; Emergencies ; Endocrine System Diseases/complications ; Hemodynamics ; Homeostasis/physiology ; Humans ; Hypertension/complications ; Hypertension/diagnosis ; Hypertension/physiopathology ; Kidney Diseases/etiology ; Kidney Diseases/physiopathology ; Nervous System Diseases/etiology ; Nervous System Diseases/physiopathology ; Organ Dysfunction Scores
Language	English
Publishing date	2017-05
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	215710-x
ISSN	1557-9859 ; 0025-7125
ISSN (online)	1557-9859
ISSN	0025-7125
DOI	10.1016/j.mcna.2016.12.007
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Article: Dual diagnosis of histiocytoid Sweet syndrome and anti-neutrophil cytoplasmic antibody-associated vasculitis.

Jónsdóttir, Hildur / Sanders, M Lee / Goettsche, Lainee / Honkanen, Iiro / Schwartz, Andrei / Holanda, Danniele / Stone, Mary S / Jabbari, Ali

JAAD case reports

2022 Volume 23, Page(s) 117–119

Language	English
Publishing date	2022-04-01
Publishing country	United States
Document type	Case Reports
ZDB-ID	2834220-3
ISSN	2352-5126
ISSN	2352-5126
DOI	10.1016/j.jdcr.2022.03.007
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Article ; Online: Expanding the access to kidney transplantation: Strategies for kidney transplant programs.

Nishio Lucar, Angie G / Patel, Ankita / Mehta, Shikha / Yadav, Anju / Doshi, Mona / Urbanski, Megan A / Concepcion, Beatrice P / Singh, Neeraj / Sanders, M Lee / Basu, Arpita / Harding, Jessica L / Rossi, Ana / Adebiyi, Oluwafisayo O / Samaniego-Picota, Milagros / Woodside, Kenneth J / Parsons, Ronald F

Clinical transplantation

2024 Volume 38, Issue 5, Page(s) e15315

Abstract: Kidney transplantation is the most successful kidney replacement therapy available, resulting in improved recipient survival and societal cost savings. Yet, nearly 70 years after the first successful kidney transplant, there are still numerous barriers ... ...

Abstract	Kidney transplantation is the most successful kidney replacement therapy available, resulting in improved recipient survival and societal cost savings. Yet, nearly 70 years after the first successful kidney transplant, there are still numerous barriers and untapped opportunities that constrain the access to transplant. The literature describing these barriers is extensive, but the practices and processes to solve them are less clear. Solutions must be multidisciplinary and be the product of strong partnerships among patients, their networks, health care providers, and transplant programs. Transparency in the referral, evaluation, and listing process as well as organ selection are paramount to build such partnerships. Providing early culturally congruent and patient-centered education as well as maximizing the use of local resources to facilitate the transplant work up should be prioritized. Every opportunity to facilitate pre-emptive kidney transplantation and living donation must be taken. Promoting the use of telemedicine and kidney paired donation as standards of care can positively impact the work up completion and maximize the chances of a living donor kidney transplant.
MeSH term(s)	Kidney Transplantation ; Humans ; Health Services Accessibility ; Tissue and Organ Procurement/methods ; Kidney Failure, Chronic/surgery ; Living Donors/supply & distribution ; Waiting Lists
Language	English
Publishing date	2024-04-30
Publishing country	Denmark
Document type	Journal Article ; Review
ZDB-ID	639001-8
ISSN	1399-0012 ; 0902-0063
ISSN (online)	1399-0012
ISSN	0902-0063
DOI	10.1111/ctr.15315
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Article: Walking Ability and Brain Natriuretic Peptide Are Highly Predictive of Kidney Transplant Waiting List Removal.

Katz, Daniel A / Ten Eyck, Patrick / Binns, Grace / Manay, Priyadarshini / Sanders, M Lee / Hornickel, Jodell L / Vu, An / Swee, Melissa / Kalil, Roberto

Transplantation direct

2023 Volume 9, Issue 6, Page(s) e1483

Abstract: Kidney transplant waitlist management is complex because waiting time is long, and the patients have significant comorbidities. Identification of patients at highest risk for waiting list removal for death and medical complications could allow better ... ...

Abstract	Kidney transplant waitlist management is complex because waiting time is long, and the patients have significant comorbidities. Identification of patients at highest risk for waiting list removal for death and medical complications could allow better outcomes and allocation of resources. Methods: Demographics, functional and frailty assessment' and biochemical data were retrospectively analyzed on 313 consecutive patients listed for kidney transplant. Troponin, brain natriuretic peptide, components of the Fried frailty metrics, pedometer activity, and treadmill ability were measured at the time of transplant evaluation and at subsequent re-evaluations. Cox proportional hazards models were used to identify factors associated with death or waiting list removal for medical reasons. Multivariate models were created to identify significant predictor sets. Results: Among 249 patients removed while waitlisted, 19 (6.1%) died and 51 (16.3%) were removed for medical reasons. Mean follow-up duration was 2.3 y (±1.5 y). 417 sets of measurements were collected. Significant ( Conclusions: Changes in functional and biochemical markers are predictive of kidney waitlist removal for death and medical reasons. BNP and measures of walking ability were of particular importance.
Language	English
Publishing date	2023-05-12
Publishing country	United States
Document type	Journal Article
ISSN	2373-8731
ISSN	2373-8731
DOI	10.1097/TXD.0000000000001483
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Article ; Online: Bridging the Gap in Competency Assessment During Transition from Undergraduate Medical Education to Graduate Medical Education: A Perspective Piece.

Anees, Amna / McAlister, Elizabeth G / Garber, Adam M / Calderon, Alvin S / Butler, James / Mallin, Emily / Levine, Diane / Sanders, M Lee / Kwan, Brian / Clewing, J Marietta / Barczi, Steven / Mateja, Candice / Ismail, Nadia

The American journal of medicine

2023 Volume 136, Issue 9, Page(s) 941–945.e1

MeSH term(s)	Humans ; Education, Medical, Undergraduate ; Education, Medical, Graduate ; Competency-Based Education ; Clinical Competence ; Curriculum
Language	English
Publishing date	2023-06-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	80015-6
ISSN	1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
ISSN (online)	1555-7162 ; 1873-2178
ISSN	0002-9343 ; 1548-2766
DOI	10.1016/j.amjmed.2023.06.001
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Article ; Online: BK virus histopathologic disease severity does not predict allograft outcome in renal transplant recipients.

Sanders, M Lee / Swee, Melissa / Fraer, Mony / Kuppachi, Sarat / Ten Eyck, Patrick / Rastogi, Prerna

Annals of diagnostic pathology

2019 Volume 42, Page(s) 1–6

Abstract: Aims: BK polyomavirus nephropathy (BKPyVN) is an important cause of allograft failure after renal transplantation. Despite early screening for the virus, allograft loss from BKPyVN is still experienced in up to 14% of all renal transplant recipients. ... ...

Abstract	Aims: BK polyomavirus nephropathy (BKPyVN) is an important cause of allograft failure after renal transplantation. Despite early screening for the virus, allograft loss from BKPyVN is still experienced in up to 14% of all renal transplant recipients. The aim of this study was to investigate the association between BKPyVN histopathologic disease severity and allograft outcome at our center. Methods: Kidney transplant recipients who had undergone transplantation between 2002 and 2014 with biopsy proven BKPyVN were eligible for this retrospective study. Each biopsy was re-evaluated by a single pathologist blinded to the clinical data and scored according to the Banff criteria for rejection and BKPyVN. Serum creatinine and BK viral load at the time of biopsy diagnosis as well as allograft outcomes to include allograft survival and serum BK viremia resolution were collected for each recipient to determine if BK virus histopathologic disease severity could predict allograft outcome. Results: Twenty cases of BKPyVN were identified from 1031 total renal transplants performed. There was no statistical association between allograft loss and BKPyVN histopathology (p = 0.49). There was also no statistical association between BKPyVN histopathology and BK viral load at the time of biopsy diagnosis (p = 0.38) or serum BK viremia resolution (p = 0.16). Conclusions: BKPyVN histopathology does not appear to be useful in predicting renal allograft outcome in those recipients diagnosed with BKPyVN which is in contrast to some previously published data.
MeSH term(s)	Adolescent ; Adult ; Aged ; Allografts ; Child ; Female ; Graft Survival ; Humans ; Kidney Diseases/virology ; Kidney Transplantation ; Male ; Middle Aged ; Polyomavirus Infections/complications ; Retrospective Studies ; Transplant Recipients ; Tumor Virus Infections/complications
Language	English
Publishing date	2019-06-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	1440011-x
ISSN	1532-8198 ; 1092-9134
ISSN (online)	1532-8198
ISSN	1092-9134
DOI	10.1016/j.anndiagpath.2019.06.012
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Article ; Online: Frailty measures can be used to predict the outcome of kidney transplant evaluation.

Manay, Priyadarshini / Ten Eyck, Patrick / Kalil, Roberto / Swee, Melissa / Sanders, M Lee / Binns, Grace / Hornickel, Jodell L / Katz, Daniel A

Surgery

2020 Volume 169, Issue 3, Page(s) 686–693

Abstract: Background: Experience incorporating frailty and functional metrics in the transplant evaluation process is limited. We hypothesized that simple tests correlate with kidney transplant listing outcomes.: Methods: Frailty metrics, treadmill ability, ... ...

Abstract	Background: Experience incorporating frailty and functional metrics in the transplant evaluation process is limited. We hypothesized that simple tests correlate with kidney transplant listing outcomes. Methods: Frailty metrics, treadmill ability, pedometer data, troponin T, and brain natriuretic peptide were collected on 375 consecutive kidney transplant evaluations between July 2015 and December 2018. Patients initially denied were compared with those listed or deferred. Frailty metrics included handgrip, chair sit-stand, up-and-go, chair sit-reach, and questions related to exhaustion. Results: A total of 95 (25%) patients were initially denied. Those denied were older, diabetic, or had higher body mass indexes. Frailty metrics including chair sit-stand, up-and-go, chair sit-reach, grip strength, and exhaustion; biochemical markers troponin and brain natriuretic peptide; and pedometer and treadmill ability were all significantly associated with denial (P < .001). The best order three model combining parsimony and predictiveness included treadmill ability, exhaustion, and troponin. The most predictive pedometer model also included exhaustion and up-and-go. The best order three model excluding biochemical markers, pedometer, and treadmill results included up-and-go, exhaustion, and chair sit-reach. Conclusion: Outcomes after on-site kidney transplant evaluation strongly correlated with the results of common clinical and functional frailty metrics.
MeSH term(s)	Aged ; Biomarkers ; Exercise Test ; Female ; Frailty/diagnosis ; Humans ; Kidney Transplantation/adverse effects ; Kidney Transplantation/statistics & numerical data ; Male ; Middle Aged ; Multivariate Analysis ; Patient Outcome Assessment ; Prognosis
Chemical Substances	Biomarkers
Language	English
Publishing date	2020-08-26
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	202467-6
ISSN	1532-7361 ; 0039-6060
ISSN (online)	1532-7361
ISSN	0039-6060
DOI	10.1016/j.surg.2020.07.016
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Article ; Online: Psychosocial characteristics of patients evaluated for kidney transplant and associations with functional and frailty metrics at a veterans affairs hospital.

Manay, Priyadarshini / Ten Eyck, Patrick / Siniff, Erin / Binns, Grace / Sanders, M Lee / Swee, Melissa / Hornickel, Jodell L / Kalil, Roberto / Katz, Daniel A

Clinical transplantation

2021 Volume 36, Issue 2, Page(s) e14530

Abstract: Background: The effect of psychosocial problems on listing outcomes and potential interactions with functional metrics is not well-characterized among Veteran transplant candidates.: Methods: The results from psychosocial evaluations, frailty metrics, ...

Abstract	Background: The effect of psychosocial problems on listing outcomes and potential interactions with functional metrics is not well-characterized among Veteran transplant candidates. Methods: The results from psychosocial evaluations, frailty metrics, and biochemical markers were collected on 375 consecutive Veteran kidney transplant candidates. Psychosocial diagnoses were compared between patients listed or denied for transplant. Functional abilities were compared among patients with or without psychosocial diagnoses and then evaluated based on reason for denial. Results: Eighty-four percent of patients had a psychosocial diagnosis. Common issues included substance or alcohol abuse (62%), psychiatric diagnoses (50%), and poor adherence (25%). Patients with psychiatric diagnoses, cognitive impairments, and poor adherence were more likely to be denied for transplant (P < .05). Patients with depression, PTSD, and anxiety did not have worse functional ability, but experienced more exhaustion than patients without these problems. Patients denied for medical but not purely psychosocial reasons had worse troponin and functional metrics compared with listed patients. Conclusion: Over 80% of patients with a psychosocial diagnosis were listed; however, poor adherence was a particularly important reason for denial for purely psychosocial reasons. Patients with psychosocial diagnoses generally were not more functionally limited than their counterparts without psychosocial diagnoses or those listed for transplant.
MeSH term(s)	Benchmarking ; Frailty ; Hospitals ; Humans ; Kidney Transplantation ; Veterans
Language	English
Publishing date	2021-11-29
Publishing country	Denmark
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	639001-8
ISSN	1399-0012 ; 0902-0063
ISSN (online)	1399-0012
ISSN	0902-0063
DOI	10.1111/ctr.14530
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Article ; Online: Development and implementation of a Telenephrology dashboard for active surveillance of kidney disease: a quality improvement project.

Swee, Melissa L / Sanders, M Lee / Phisitkul, Kantima / Bailey, George / Thumann, Angie / Neuzil, Nikki / Kumar, Bharat / O'Shea, Amy M J / Dixon, Bradley S

BMC nephrology

2020 Volume 21, Issue 1, Page(s) 424

Abstract: Background: Kidney disease accounts for more than 49 billion dollars in healthcare expenditures annually. Early detection and intervention may reduce the burden of disease. We describe a quality improvement project to develop a telenephrology dashboard ... ...

Abstract	Background: Kidney disease accounts for more than 49 billion dollars in healthcare expenditures annually. Early detection and intervention may reduce the burden of disease. We describe a quality improvement project to develop a telenephrology dashboard that proactively monitors kidney disease. Methods: One hundred eighty-four thousands Veterans within the Iowa City Veterans Affairs Health Care System were eligible for telenephrology consultation. The dashboard accessed the charts of 53,085 Veterans at risk for kidney disease. We utilized Lean-Six Sigma tools and principles and the Define-Measure-Analyze-Improve-Control Framework to develop and deploy a telenephrology dashboard in 4 community-based outpatient clinics (CBOCs). The primary measure was the number of days to complete consultation. Secondary measures included number of electronic consultations per month, distance and cost of Veteran travel saved, and number of steps for completion of consult. Results: The data of 1384 Veterans at the 4 CBOCs were analyzed by the telenephrology dashboard, of which 459 generated telenephrology consults. The number of days to complete any type of consultation was unchanged (48.9 days in 2019, compared to 41.6 days in 2017). The average Veteran saved between $21.60 to $63.90 per trip to Iowa City. Between March 2019 and August 2019, there were 27.3 telenephrology consults per month. The number of steps needed to complete the consult request was decreased from 13 to 9. Conclusions: Utilization of the telenephrology dashboard system contributed to an increase in consultations completed through electronic means without decreasing face-to-face consults. Electronic consults now outnumber traditional face-to-face consultations at our institution. Telenephrology consultation improved early detection and identification of kidney disease and saved time and costs for Veterans in travel, but did not decrease the average number of days to complete consultation requests.
MeSH term(s)	Attitude to Computers ; Data Display ; Delivery of Health Care ; Humans ; Kidney Diseases ; Nephrology ; Quality Improvement ; Rural Health Services ; Telemedicine ; Total Quality Management ; United States ; United States Department of Veterans Affairs ; User-Computer Interface ; Veterans
Language	English
Publishing date	2020-10-06
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2041348-8
ISSN	1471-2369 ; 1471-2369
ISSN (online)	1471-2369
ISSN	1471-2369
DOI	10.1186/s12882-020-02077-0
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