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  1. Article ; Online: Commentary on "Same-Sex Marriage and Common Mental Health Diagnoses: A Sibling Comparison and Adoption Approach".

    Sanders, Stephanie A

    Journal of sex research

    2022  Volume 60, Issue 5, Page(s) 605–607

    Abstract: This is a commentary on "Same-sex Marriage and Common Mental Health Diagnoses: A Sibling Comparison and Adoption Approach" by Xu, Rahman, Hiyoshi, and Montgomery. It considers the advantages and disadvantages of the study design and the contribution the ... ...

    Abstract This is a commentary on "Same-sex Marriage and Common Mental Health Diagnoses: A Sibling Comparison and Adoption Approach" by Xu, Rahman, Hiyoshi, and Montgomery. It considers the advantages and disadvantages of the study design and the contribution the study makes to the scientific literature. Discussed are issues of phenotype accuracy especially with respect to sexual orientation and other potential confounds, and some comments on common misunderstandings of the meaning and implications of findings of genetic correlations to human behavior.
    MeSH term(s) Humans ; Male ; Female ; Siblings ; Mental Health ; Marriage/psychology ; Sexual Behavior
    Language English
    Publishing date 2022-11-18
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 220889-1
    ISSN 1559-8519 ; 0022-4499
    ISSN (online) 1559-8519
    ISSN 0022-4499
    DOI 10.1080/00224499.2022.2134286
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 614: Show issues Location:
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  2. Article ; Online: Expanding the bandwidth of fluorescence-detected two-dimensional electronic spectroscopy using a broadband continuum probe pulse pair.

    Sanders, Stephanie E / Zhang, Muyi / Javed, Ariba / Ogilvie, Jennifer P

    Optics express

    2024  Volume 32, Issue 6, Page(s) 8887–8902

    Abstract: We demonstrate fluorescence-detected two-dimensional electronic spectroscopy (F-2DES) with a broadband, continuum probe pulse pair in the pump-probe geometry. The approach combines a pump pulse pair generated by an acousto-optic pulse-shaper with precise ...

    Abstract We demonstrate fluorescence-detected two-dimensional electronic spectroscopy (F-2DES) with a broadband, continuum probe pulse pair in the pump-probe geometry. The approach combines a pump pulse pair generated by an acousto-optic pulse-shaper with precise control of the relative pump pulse phase and time delay with a broadband, continuum probe pulse pair created using the Translating Wedge-based Identical pulses eNcoding System (TWINS). The continuum probe expands the spectral range of the detection axis and lengthens the waiting times that can be accessed in comparison to implementations of F-2DES using a single pulse-shaper. We employ phase-cycling of the pump pulse pair and take advantage of the separation of signals in the frequency domain to isolate rephasing and non-rephasing signals and optimize the signal-to-noise ratio. As proof of principle, we demonstrate broadband F-2DES on a laser dye and bacteriochlorophyll a.
    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.516963
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  3. Article ; Online: Wedge-Based Design for Phase Stable and Phase Accurate Heterodyne-Detected Sum-Frequency Generation Spectroscopy.

    Sanders, Stephanie E / Stingel, Ashley M / Petersen, Poul B

    The journal of physical chemistry letters

    2022  Volume 13, Issue 9, Page(s) 2072–2077

    Abstract: Phase sensitive and heterodyne-detected (HD) sum-frequency generation (SFG) spectroscopy offers the ability to separate the nonlinear susceptibility into its real and imaginary components. This provides information about the absolute orientation of ... ...

    Abstract Phase sensitive and heterodyne-detected (HD) sum-frequency generation (SFG) spectroscopy offers the ability to separate the nonlinear susceptibility into its real and imaginary components. This provides information about the absolute orientation of molecules at interfaces while also producing an absorptive spectrum that is linear in spectral composition and can easily be decomposed into different spectral components. However, simultaneously obtaining phase accuracy and phase stability remains a challenge in SFG. Here we present a new experimental design for HD-SFG spectroscopy that incorporates a wedge pair to accurately control the timing between the local oscillator and the sample signal. This experimental approach provides high phase accuracy and long-time phase stability in a compact and flexible configuration.
    Language English
    Publishing date 2022-02-25
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.1c04175
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  4. Article ; Online: Challenges to Successful Implementation of the Immune Checkpoint Inhibitors for Treatment of Glioblastoma.

    Sanders, Stephanie / Debinski, Waldemar

    International journal of molecular sciences

    2020  Volume 21, Issue 8

    Abstract: Glioblastoma (GBM) is the most common and aggressive malignant glioma, treatment of which has not improved significantly in many years. This is due to the unique challenges that GBM tumors present when designing and implementing therapies. Recently, ... ...

    Abstract Glioblastoma (GBM) is the most common and aggressive malignant glioma, treatment of which has not improved significantly in many years. This is due to the unique challenges that GBM tumors present when designing and implementing therapies. Recently, immunotherapy in the form of immune checkpoint inhibition (ICI) has revolutionized the treatment of various malignancies. The application of immune checkpoint inhibition in GBM treatment has shown promising preclinical results. Unfortunately, this has met with little to no success in the clinic thus far. In this review, we will discuss the challenges presented by GBM tumors that likely limit the effect of ICI and discuss the approaches being tested to overcome these challenges.
    MeSH term(s) B7-H1 Antigen/immunology ; B7-H1 Antigen/metabolism ; Blood-Brain Barrier/metabolism ; Brain Neoplasms/drug therapy ; CTLA-4 Antigen/immunology ; CTLA-4 Antigen/metabolism ; Clinical Trials as Topic ; Glioblastoma/drug therapy ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Immunotherapy ; Programmed Cell Death 1 Receptor/immunology ; Programmed Cell Death 1 Receptor/metabolism
    Chemical Substances B7-H1 Antigen ; CD274 protein, human ; CTLA-4 Antigen ; Immune Checkpoint Inhibitors ; Programmed Cell Death 1 Receptor
    Language English
    Publishing date 2020-04-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21082759
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  5. Article ; Online: Heterodyne-detected sum frequency generation of water at surfaces with varying hydrophobicity.

    Sanders, Stephanie E / Petersen, Poul B

    The Journal of chemical physics

    2019  Volume 150, Issue 20, Page(s) 204708

    Abstract: Aqueous surfaces mediate many atmospheric, biological, and technological processes. At the interface, the bulk hydrogen-bonding network is terminated and the interfacial water molecules restructure according to the surface chemistry of the interface. ... ...

    Abstract Aqueous surfaces mediate many atmospheric, biological, and technological processes. At the interface, the bulk hydrogen-bonding network is terminated and the interfacial water molecules restructure according to the surface chemistry of the interface. Given the complexity of both natural and technical aqueous interfaces, self-assembled monolayers provide a platform for controllably tuning the chemical composition of the surface and thus the water restructuring. Here, we study a hydrophobic monolayer, a hydrophilic monolayer, and a mixed hydrophobic/hydrophilic monolayer in contact with water. Monolayers composed of both hydrophilic and hydrophobic chains mimic the complex and heterogeneous chemical composition of natural and technological surfaces. By employing heterodyne-detected sum frequency generation, the purely absorptive vibrational line shape of interfacial water is measured experimentally. We examined the structure of the interfacial water in contact with each of the monolayers by analyzing the relative dipole moment orientations and fitting the imaginary component of χ
    Language English
    Publishing date 2019-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/1.5078587
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    In stock of ZB MED Bonn / Germany

    Z 4' 49/16: Show issues

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  6. Book ; Thesis: Psychological correlates of menstrual cycle length and variability

    Sanders, Stephanie A.

    1984  

    Author's details by Stephanie Ann Sanders
    Size XV, 158 S. : graph. Darst.
    Publishing country United States
    Document type Book ; Thesis
    Thesis / German Habilitation thesis New Brunswick, NJ, Rutgers Univ., Diss., 1984
    Note Kopie, erschienen im Verl. Univ. Microfilms Internat., Ann Arbor, Mich., 1988
    HBZ-ID HT003264356
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    89 E 270 order for loan Magazin

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  7. Article ; Online: On the Trail of Molecular Hydrophilicity and Hydrophobicity at Aqueous Interfaces.

    Chen, Wanlin / Sanders, Stephanie E / Özdamar, Burak / Louaas, Dorian / Brigiano, Flavio Siro / Pezzotti, Simone / Petersen, Poul B / Gaigeot, Marie-Pierre

    The journal of physical chemistry letters

    2023  Volume 14, Issue 5, Page(s) 1301–1309

    Abstract: Uncovering microscopic hydrophilicity and hydrophobicity at heterogeneous aqueous interfaces is essential as it dictates physico/chemical properties such as wetting, the electrical double layer, and reactivity. Several molecular and spectroscopic ... ...

    Abstract Uncovering microscopic hydrophilicity and hydrophobicity at heterogeneous aqueous interfaces is essential as it dictates physico/chemical properties such as wetting, the electrical double layer, and reactivity. Several molecular and spectroscopic descriptors were proposed, but a major limitation is the lack of connections between them. Here, we combine density functional theory-based MD simulations (DFT-MD) and SFG spectroscopy to explore how interfacial water responds in contact with self-assembled monolayers (SAM) of tunable hydrophilicity. We introduce a microscopic metric to track the transition from hydrophobic to hydrophilic interfaces. This metric combines the H/V descriptor, a structural descriptor based on the preferential orientation within the water network in the topmost binding interfacial layer (BIL) and spectroscopic fingerprints of H-bonded and dangling OH groups of water carried by BIL-resolved SFG spectra. This metric builds a bridge between molecular descriptors of hydrophilicity/hydrophobicity and spectroscopically measured quantities and provides a recipe to quantitatively or qualitatively interpret experimental SFG signals.
    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.2c03300
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  8. Article ; Online: "Sex" and the Ace Spectrum: Definitions of Sex, Behavioral Histories, and Future Interest for Individuals Who Identify as Asexual, Graysexual, or Demisexual.

    Hille, Jessica J / Simmons, Megan K / Sanders, Stephanie A

    Journal of sex research

    2019  Volume 57, Issue 7, Page(s) 813–823

    Abstract: This paper explores how people ( ...

    Abstract This paper explores how people (
    MeSH term(s) Humans ; Sexual Behavior
    Language English
    Publishing date 2019-12-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 220889-1
    ISSN 1559-8519 ; 0022-4499
    ISSN (online) 1559-8519
    ISSN 0022-4499
    DOI 10.1080/00224499.2019.1689378
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 614: Show issues Location:
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  9. Article ; Online: Comment on "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior".

    Hamer, Dean / Mustanski, Brian / Sell, Randall / Sanders, Stephanie A / Garcia, Justin R

    Science (New York, N.Y.)

    2021  Volume 371, Issue 6536

    Abstract: The phenotypic measures used by ... ...

    Abstract The phenotypic measures used by Ganna
    MeSH term(s) Bisexuality ; Genome-Wide Association Study ; Heterosexuality ; Homosexuality ; Humans ; Sexual Behavior
    Language English
    Publishing date 2021-03-22
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.aba2941
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    In stock of ZB MED Cologne/Königswinter

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  10. Article ; Online: Water at surfaces with tunable surface chemistries.

    Sanders, Stephanie E / Vanselous, Heather / Petersen, Poul B

    Journal of physics. Condensed matter : an Institute of Physics journal

    2018  Volume 30, Issue 11, Page(s) 113001

    Abstract: Aqueous interfaces are ubiquitous in natural environments, spanning atmospheric, geological, oceanographic, and biological systems, as well as in technical applications, such as fuel cells and membrane filtration. Where liquid water terminates at a ... ...

    Abstract Aqueous interfaces are ubiquitous in natural environments, spanning atmospheric, geological, oceanographic, and biological systems, as well as in technical applications, such as fuel cells and membrane filtration. Where liquid water terminates at a surface, an interfacial region is formed, which exhibits distinct properties from the bulk aqueous phase. The unique properties of water are governed by the hydrogen-bonded network. The chemical and physical properties of the surface dictate the boundary conditions of the bulk hydrogen-bonded network and thus the interfacial properties of the water and any molecules in that region. Understanding the properties of interfacial water requires systematically characterizing the structure and dynamics of interfacial water as a function of the surface chemistry. In this review, we focus on the use of experimental surface-specific spectroscopic methods to understand the properties of interfacial water as a function of surface chemistry. Investigations of the air-water interface, as well as efforts in tuning the properties of the air-water interface by adding solutes or surfactants, are briefly discussed. Buried aqueous interfaces can be accessed with careful selection of spectroscopic technique and sample configuration, further expanding the range of chemical environments that can be probed, including solid inorganic materials, polymers, and water immiscible liquids. Solid substrates can be finely tuned by functionalization with self-assembled monolayers, polymers, or biomolecules. These variables provide a platform for systematically tuning the chemical nature of the interface and examining the resulting water structure. Finally, time-resolved methods to probe the dynamics of interfacial water are briefly summarized before discussing the current status and future directions in studying the structure and dynamics of interfacial water.
    Language English
    Publishing date 2018-02-02
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/aaacb5
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