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Article ; Online: The untold story of missing data in disaster research

Rebecca Louise Jones / Aditi Kharb / Sandy Tubeuf

Environmental Research Letters, Vol 18, Iss 10, p

a systematic review of the empirical literature utilising the Emergency Events Database (EM-DAT)

2023 Volume 103006

Abstract: Global disaster databases are prone to missing data. Neglect or inappropriate handling of missing data can bias statistical analyses. Consequently, this risks the reliability of study results and the wider evidence base underlying climate and disaster ... ...

Abstract	Global disaster databases are prone to missing data. Neglect or inappropriate handling of missing data can bias statistical analyses. Consequently, this risks the reliability of study results and the wider evidence base underlying climate and disaster policies. In this paper, a comprehensive systematic literature review was conducted to determine how missing data have been acknowledged and handled in disaster research. We sought empirical, quantitative studies that utilised the Emergency Events Database (EM-DAT) as a primary or secondary data source to capture an extensive sample of the disaster literature. Data on the acknowledgement and handling of missing data were extracted from all eligible studies. Descriptive statistics and univariate correlation analysis were used to identify trends in the consideration of missing data given specific study characteristics. Of the 433 eligible studies, 44.6% acknowledged missing data, albeit briefly, and 33.5% attempted to handle missing data. Studies having a higher page count were significantly (p < 0.01) less prone to acknowledge or handle missing data, whereas the research field of the publication journal distinguished between papers that simply acknowledged missing data, with those that both acknowledged and handled missing data (p < 0.100). A variety of methods to handle missing data (n = 24) were identified. However, these were commonly ad-hoc with little statistical basis. The broad method used to handle missing data: imputation, augmentation or deletion was significantly (p < 0.001) correlated with the geographical scope of the study. This systematic review reveals large failings of the disaster literature to adequately acknowledge and handle missing data. Given these findings, more insight is required to guide a standard practice of handling missing data in disaster research.
Keywords	missing data ; disaster database ; EM-DAT ; systematic review ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350 ; Science ; Q ; Physics ; QC1-999
Subject code	310
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	IOP Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Searching for Sustainability in Health Systems

Florence Degavre / Suzanne Kieffer / David Bol / Rémi Dekimpe / Charlotte Desterbecq / Thibault Pirson / Georgiana Sandu / Sandy Tubeuf

Sustainability, Vol 14, Iss 5286, p

Toward a Multidisciplinary Evaluation of Mobile Health Innovations

2022 Volume 5286

Abstract: Mobile health (mHealth) innovations are considered by governments as game changers toward more sustainable health systems. The existing literature focuses on the clinical aspects of mHealth but lacks an integrated framework on its sustainability. The ... ...

Abstract	Mobile health (mHealth) innovations are considered by governments as game changers toward more sustainable health systems. The existing literature focuses on the clinical aspects of mHealth but lacks an integrated framework on its sustainability. The foundational idea for this paper is to include disciplinary complementarities into a multi-dimensional vision to evaluate the non-clinical aspects of mHealth innovations. We performed a targeted literature review to find how the sustainability of mHealth innovations was appraised in each discipline. We found that each discipline considers a different outcome of interest and adopts different time horizons and perspectives for the evaluation. This article reflects on how the sustainability of mHealth innovation can be assessed at both the level of the device itself as well as the level of the health system. We identify some of the challenges ahead of researchers working on mobile health innovations in contributing to shaping a more sustainable health system.
Keywords	mobile health ; sustainable health system ; health technology assessment ; life-cycle assessment ; eco-design ; transformative innovation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	360
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comparison of ALitretinoin with PUVA as the first-line treatment in patients with severe chronic HAnd eczema (ALPHA)

Catherine Smith / Miriam Wittmann / Fiona Cowdell / Sarah Brown / Catherine Reynolds / Catherine Fernandez / Sandy Tubeuf / Jane Nixon / Rachael Gilberts / Mark Goodfield / Isabelle L Smith / John T Lear / Lesley Sunderland / Cathy Green / Philip Hampton / Amy Barker / Armando Vargas-Palacios

BMJ Open, Vol 12, Iss

study protocol for a randomised controlled trial

2022 Volume 2

Keywords	Medicine ; R
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A cluster RCT and process evaluation of an implementation optimisation intervention to promote parental engagement enrolment and attendance in a childhood obesity prevention programme

Maria Bryant / Wendy Burton / Michelle Collinson / Amanda Farrin / Jane Nixon / June Stevens / Kim Roberts / Robbie Foy / Harry Rutter / Bethan Copsey / Suzanne Hartley / Sandy Tubeuf / Julia Brown

Trials, Vol 22, Iss 1, Pp 1-

results of the Optimising Family Engagement in HENRY (OFTEN) trial

2021 Volume 21

Abstract: Abstract Background Poor and variable implementation of childhood obesity prevention programmes reduces their population impact and sustainability. We drew upon ethnographic work to develop a multi-level, theory-based implementation optimisation ... ...

Abstract	Abstract Background Poor and variable implementation of childhood obesity prevention programmes reduces their population impact and sustainability. We drew upon ethnographic work to develop a multi-level, theory-based implementation optimisation intervention. This intervention aimed to promote parental enrolment and attendance at HENRY (Health Exercise Nutrition for the Really Young), a UK community obesity prevention programme, by changing behaviours of children’s centre and local authority stakeholders. Methods We evaluated the effectiveness of the implementation optimisation intervention on HENRY programme enrolment and attendance over a 12-month implementation period in a cluster randomised controlled trial. We randomised 20 local government authorities (with 126 children’s centres) to HENRY plus the implementation optimisation intervention or to HENRY alone. Primary outcomes were (1) the proportion of centres enrolling at least eight parents per programme and (2) the proportion of centres with a minimum of 75% of parents attending at least five of eight sessions per programme. Trial analyses adjusted for stratification factors (pre-randomisation implementation of HENRY, local authority size, deprivation) and allowed for cluster design. A parallel mixed-methods process evaluation used qualitative interviews and routine monitoring to explain trial results. Results Neither primary outcome differed significantly between groups; 17.8% of intervention centres and 18.0% of control centres achieved the parent enrolment target (adjusted difference − 1.2%; 95% CI − 19.5%, 17.1%); 17.1% of intervention centres and 13.9% of control centres achieved the attendance target (adjusted difference 1.2%; 95% CI − 15.7%, 18.1%). Unexpectedly, the trial coincided with substantial national service restructuring, including centre closures and reduced funds. Some commissioning and management teams stopped or reduced delivery of both HENRY and the implementation optimisation intervention due to competing demands. Thus, at follow-up, ...
Keywords	Community ; Parent ; Engagement ; Enrolment ; Attendance ; Obesity ; Medicine (General) ; R5-920
Subject code	360
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Problem-solving therapy rather than treatment as usual for adults after self-harm

David Owens / Alexandra Wright-Hughes / Liz Graham / Paul Blenkiron / Kayleigh Burton / Michelle Collinson / Amanda Farrin / Simon Hatcher / Katie Martin / John O’Dwyer / Louise Pembroke / David Protheroe / Sandy Tubeuf / Allan House

Pilot and Feasibility Studies, Vol 6, Iss 1, Pp 1-

a pragmatic, feasibility, randomised controlled trial (the MIDSHIPS trial)

2020 Volume 14

Abstract: Abstract Background Non-fatal self-harm is one of the commonest reasons for adults’ emergency hospital attendance. Although strongly associated with fatal and non-fatal repetition, there is weak evidence about effective interventions—and no clear NICE ... ...

Abstract	Abstract Background Non-fatal self-harm is one of the commonest reasons for adults’ emergency hospital attendance. Although strongly associated with fatal and non-fatal repetition, there is weak evidence about effective interventions—and no clear NICE guidance or clinical consensus concerning aftercare. We examined the practicability of a definitive trial to evaluate problem-solving therapy (PST) to reduce repetition of self-harm; MIDSHIPS is a single-centre, parallel-group, individually randomised controlled feasibility trial comparing treatment-as-usual (TAU) alone to TAU plus up to six sessions of brief problem-solving therapy (PST) with adults who had recently attended hospital because of self-harm. Objectives were to adapt the intervention for a UK setting, train therapists, recruit and randomise patients, deliver PST under supervision, and establish comparative outcomes, assessed blindly. Methods We adapted the problem-solving intervention from an earlier trial and trained a mental-health nurse to deliver it. Adult patients attending the general hospital for self-harm were recruited while undergoing psychosocial assessment by the mental health team, and 62 were randomly allocated (32 TAU, 30 PST). The primary outcome assessed repeat hospital attendance due to further self-harm 6 months post-randomisation. Secondary outcomes included participant-reported outcomes and service use at 3 and 6 months post-randomisation. Results The recruitment period had to be extended and 710 patients screened in order to establish a trial sample of the planned size (N = 62). A quarter of participants allocated to PST did not undertake the therapy offered; those who received PST attended a median of three sessions. Secondary outcomes were established for 49 (79%) participants at 6 months; all participants’ hospital records were retrieved. Repetition of self-harm leading to hospital presentation occurred in 19 of the 62 participants (30.6%, 95% CI 19.2%, 42.1%) within 6 months of randomisation. Promising differential rates of self-harm were observed with an event rate of 23.3% (95% CI 8.2%, 38.5%) in the PST arm; and 37.5% (95% CI 20.7%, 54.3%) in TAU. Economic findings were also encouraging, with a small QALY gain (0.0203) in the PST arm together with less reported use of the NHS in the PST arm (average £2120) than with TAU-only (£2878). Conclusions The feasibility trial achieved its objectives despite considerable difficulties with recruitment—adapting the PST, training a therapist, recruiting patients who had recently self-harmed, delivering the therapy, and establishing primary and secondary outcomes. These data provide a robust platform for a definitive multicentre randomised controlled trial of brief problem-solving therapy after hospital attendance due to self-harm. Trial registration Identification number and URL: ISRCTN54036115 http://www.isrctn.com/search?q=midships . Registered: 13 January 2012
Keywords	Self-harm ; Problem-solving therapy ; Self-poisoning ; Self-injury ; Adults ; Feasibility RCT ; Medicine (General) ; R5-920
Subject code	150
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The impact of care farms on quality of life, depression and anxiety among different population groups

Jenni Murray / Nyantara Wickramasekera / Marjolein Elings / Rachel Bragg / Cathy Brennan / Zoe Richardson / Judy Wright / Marina G. Llorente / Janet Cade / Darren Shickle / Sandy Tubeuf / Helen Elsey

Campbell Systematic Reviews, Vol 15, Iss 4, Pp n/a-n/a (2019)

A systematic review

2019

Abstract: Abstract Care farming (also called social farming) is the therapeutic use of agricultural and farming practices. Service users and communities supported through care farming include people with learning disabilities, mental and physical health problems, ... ...

Abstract	Abstract Care farming (also called social farming) is the therapeutic use of agricultural and farming practices. Service users and communities supported through care farming include people with learning disabilities, mental and physical health problems, substance misuse, adult offenders, disaffected youth, socially isolated older people and the long term unemployed. Care farming is growing in popularity, especially around Europe. This review aimed to understand the impact of care farming on quality of life, depression and anxiety, on a range of service user groups. It also aimed to explore and explain the way in which care farming might work for different groups. By reviewing interview studies we found that people valued, among other things, being in contact with each other, and feeling a sense of achievement, fulfilment and belonging. Some groups seemed to appreciate different things indicating that different groups may benefit in different ways but, it is unclear if this is due to a difference in the types of activities or the way in which people take different things from the same activity. We found no evidence that care farms improved people's quality of life and some evidence that they might improve depression and anxiety. Larger studies involving single service user groups and fully validated outcome measures are needed to prove more conclusive evidence about the benefits of care farming.
Keywords	Social Sciences ; H
Subject code	360
Language	English
Publishing date	2019-12-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact and cost-effectiveness of care farms on health and well-being of offenders on probation

Helen Elsey / Rachel Bragg / Marjolein Elings / Cathy Brennan / Tracey Farragher / Sandy Tubeuf / Rochelle Gold / Darren Shickle / Nyantara Wickramasekera / Zoe Richardson / Janet Cade / Jenni Murray

Public Health Research, Vol 6, Iss

a pilot study

2018 Volume 3

Abstract: Background: Care farms (CFs), in which all or part of the farm is used for therapeutic purposes, show potential for improving well-being for disadvantaged groups. We assessed the feasibility of determining the cost-effectiveness of CFs in improving ... ...

Abstract	Background: Care farms (CFs), in which all or part of the farm is used for therapeutic purposes, show potential for improving well-being for disadvantaged groups. We assessed the feasibility of determining the cost-effectiveness of CFs in improving quality of life compared with comparator sites among probationers undertaking community orders (COs). Objectives: (1) To conduct a systematic review of CF impacts and mechanisms in improving health and logic model development; (2) to inform future studies by estimating differences in quality of life and other outcomes, identifying factors driving CO allocation and ways to maximise recruitment and follow-up; and (3) to assess feasibility of cost-effectiveness analysis. Review methods: A mixed-methods synthesis following Campbell Collaboration guidelines. Pilot study: three probation service regions in England, each with a CF and a comparator CO site. Participants were adult offenders (aged ≥ 18 years) serving COs. The primary outcome was quality of life [as measured via the Clinical Outcome in Routine Evaluation–Outcome Measure (CORE-OM)]. Other outcomes were health behaviours, mental well-being, connectedness to nature and reconvictions. Data sources: In November 2014, we searched 22 health, education, environmental, criminal justice and social science electronic databases, databases of grey literature and care farming websites across Europe. There were no language restrictions. A full list of databases searched is given in Appendix 1; some examples include Web of Science, Cumulative Index to Nursing and Allied Health Literature (via EBSCOhost), The Campbell Library, Criminal Justice Abstracts (via EBSCOhost), MEDLINE (via Ovid) and Scopus (Elsevier B.V., Amsterdam, the Netherlands). Results: Our systematic review identified 1659 articles: 14 qualitative, 12 quantitative and one mixed-methods study. Small sample sizes and poor design meant that all were rated as being at a high risk of bias. Components of CFs that potentially improve health are being in a group, the ...
Keywords	care farms ; offenders ; probation ; community orders ; green care ; Public aspects of medicine ; RA1-1270
Subject code	360
Language	English
Publishing date	2018-02-01T00:00:00Z
Publisher	NIHR Journals Library
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A programme theory for liaison mental health services in England

Allan House / Elspeth Guthrie / Andrew Walker / Jenny Hewsion / Peter Trigwell / Cathy Brennan / Mike Crawford / Carolyn Czoski Murray / Matt Fossey / Claire Hulme / Adam Martin / Alan Quirk / Sandy Tubeuf

BMC Health Services Research, Vol 18, Iss 1, Pp 1-

2018 Volume 11

Abstract: Abstract Background Mechanisms by which liaison mental health services (LMHS) may bring about improved patient and organisational outcomes are poorly understood. A small number of logic models have been developed, but they fail to capture the complexity ... ...

Abstract	Abstract Background Mechanisms by which liaison mental health services (LMHS) may bring about improved patient and organisational outcomes are poorly understood. A small number of logic models have been developed, but they fail to capture the complexity of clinical practice. Method We synthesised data from a variety of sources including a large national survey, 73 in-depth interviews with acute and liaison staff working in hospitals with different types of liaison mental health services, and relevant local, national and international literature. We generated logic models for two common performance indicators used to assess organisational outcomes for LMHS: response times in the emergency department and hospital length of stay for people with mental health problems. Results We identified 8 areas of complexity that influence performance, and 6 trade-offs which drove the models in different directions depending upon the balance of the trade-off. The logic models we developed could only be captured by consideration of more than one pass through the system, the complexity in which they operated, and the trade-offs that occurred. Conclusions Our findings are important for commissioners of liaison services. Reliance on simple target setting may result in services that are unbalanced and not patient-centred. Targets need to be reviewed on a regular basis, together with other data that reflect the wider impact of the service, and any external changes in the system that affect the performance of LMHS, which are beyond their control.
Keywords	Consultation-liaison psychiatry ; Liaison mental health services ; Theories of change ; Logic models ; Programme theory ; Public aspects of medicine ; RA1-1270
Subject code	360
Language	English
Publishing date	2018-09-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: TIGA-CUB – manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5–11 years with treatment-resistant conduct disorders and their primary carers

Elizabeth Edginton / Rebecca Walwyn / Kayleigh Burton / Robert Cicero / Liz Graham / Sadie Reed / Sandy Tubeuf / Maureen Twiddy / Alex Wright-Hughes / Lynda Ellis / Dot Evans / Tom Hughes / Nick Midgley / Paul Wallis / David Cottrell

Trials, Vol 18, Iss 1, Pp 1-

study protocol for a randomised controlled feasibility trial

2017 Volume 16

Abstract: Abstract Background The National Institute for Health and Care Excellence (NICE) recommends evidence-based parenting programmes as a first-line intervention for conduct disorders (CD) in children aged 5–11 years. As these are not effective in 25–33% of ... ...

Abstract	Abstract Background The National Institute for Health and Care Excellence (NICE) recommends evidence-based parenting programmes as a first-line intervention for conduct disorders (CD) in children aged 5–11 years. As these are not effective in 25–33% of cases, NICE has requested research into second-line interventions. Child and Adolescent Psychotherapists (CAPTs) address highly complex problems where first-line treatments have failed and there have been small-scale studies of Psychoanalytic Child Psychotherapy (PCP) for CD. A feasibility trial is needed to determine whether a confirmatory trial of manualised PCP (mPCP) versus Treatment as Usual (TaU) for CD is practicable or needs refinement. The aim of this paper is to publish the abridged protocol of this feasibility trial. Methods and design TIGA-CUB (Trial on improving Inter-Generational Attachment for Children Undergoing Behaviour problems) is a two-arm, pragmatic, parallel-group, multicentre, individually randomised (1:1) controlled feasibility trial (target n = 60) with blinded outcome assessment (at 4 and 8 months), which aims to develop an optimum practicable protocol for a confirmatory, pragmatic, randomised controlled trial (RCT) (primary outcome: child’s behaviour; secondary outcomes: parental reflective functioning and mental health, child and parent quality of life), comparing mPCP and TaU as second-line treatments for children aged 5–11 years with treatment-resistant CD and inter-generational attachment difficulties, and for their primary carers. Child-primary carer dyads will be recruited following a referral to, or re-referral within, National Health Service (NHS) Child and Adolescent Mental Health Services (CAMHS) after an unsuccessful first-line parenting intervention. PCP will be delivered by qualified CAPTs working in routine NHS clinical practice, using a trial-specific PCP manual (a brief version of established PCP clinical practice). Outcomes are: (1) feasibility of recruitment methods, (2) uptake and follow-up rates, (3) therapeutic delivery, treatment retention and attendance, intervention adherence rates, (4) follow-up data collection, and (5) statistical, health economics, process evaluation, and qualitative outcomes. Discussion TIGA-CUB will provide important information on the feasibility and potential challenges of undertaking a confirmatory RCT to evaluate the effectiveness and cost-effectiveness of mPCP. Trial registration Current Controlled Trials, ID: ISRCTN86725795 . Registered on 31 May 2016.
Keywords	Randomised controlled trial ; Psychoanalytic child psychotherapy ; Conduct disorders ; Treatment-resistant ; Inter-generational attachment ; Medicine (General) ; R5-920
Subject code	360
Language	English
Publishing date	2017-09-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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