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  1. Article ; Online: Leiomyosarcoma of the right gonadal vein.

    Puerta Vicente, Ana / Sanjuanbenito, Alfonso / Lobo, Eduardo

    Cirugia espanola

    2021  Volume 99, Issue 10, Page(s) 764–766

    MeSH term(s) Humans ; Leiomyosarcoma ; Vascular Neoplasms ; Veins
    Language English
    Publishing date 2021-11-08
    Publishing country Spain
    Document type Case Reports
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2021.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Leiomyosarcoma of the right gonadal vein.

    Puerta Vicente, Ana / Sanjuanbenito, Alfonso / Lobo, Eduardo

    Cirugia espanola

    2020  

    Title translation Leiomiosarcoma de vena gonadal derecha.
    Language Spanish
    Publishing date 2020-10-31
    Publishing country Spain
    Document type Case Reports
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.ciresp.2020.09.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Assesment, impact and management of moderate and severe duodenopancreatectomy complications.

    Pastor-Peinado, Paula / Ocaña, Juan / Lobo, Eduardo / Fernández-Cebrían, José María / Sanjuanbenito, Alfonso

    Cirugia espanola

    2022  Volume 100, Issue 5, Page(s) 314–316

    MeSH term(s) Humans ; Pancreatectomy ; Pancreatic Neoplasms/surgery ; Pancreaticoduodenectomy/adverse effects
    Language English
    Publishing date 2022-04-25
    Publishing country Spain
    Document type Case Reports
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2021.04.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Anterograde intraoperative pancreatic stent placement and round ligament patch to prevent pancreatic fistula after distal pancreatectomy.

    Ocaña, Juan / Sanjuanbenito, Alfonso / Lobo, Eduardo / Fernández-Cebrián, José María

    Cirugia espanola

    2020  Volume 99, Issue 5, Page(s) 374–378

    Abstract: Postoperative pancreatic fistula in distal pancreatectomy is one of the most important complications in this surgery and it is associated with high morbidity and mortality. Pancreatic fistula after distal pancreatectomy remains an unsolved problem and ... ...

    Title translation Colocación intraoperatoria anterógrada de stent pancreático y plastia de ligamento redondo para prevenir la fístula pancreática tras la pancreatectomía distal.
    Abstract Postoperative pancreatic fistula in distal pancreatectomy is one of the most important complications in this surgery and it is associated with high morbidity and mortality. Pancreatic fistula after distal pancreatectomy remains an unsolved problem and none preventive procedure has been shown effectively. We present a new technique that combine pancreatic stent placement with round ligament autologous patch over pancreatic edge. A guide is introduced through Wirsung duct prior to stent placement. After stent assessment, Wirsung duct is closed. Finally, falciform ligament autologous patch is placed over pancreatic edge. After 6-8 weeks, the stent is removed by oral endoscopy. This technique introduces a new issue on the pancreatic fistula prevention.
    Language Spanish
    Publishing date 2020-12-30
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.ciresp.2020.11.016
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  5. Article ; Online: Surgery of pancreatic metastasis from renal cell carcinoma.

    Vilar Tabanera, Alberto / Muñoz Muñoz, Paula / Molina Villar, José Manuel / Gajate, Pablo / Sanjuanbenito, Alfonso

    Cirugia espanola

    2021  Volume 100, Issue 1, Page(s) 50–52

    MeSH term(s) Carcinoma, Renal Cell/surgery ; Humans ; Kidney Neoplasms/surgery ; Pancreatic Neoplasms/surgery
    Language English
    Publishing date 2021-12-01
    Publishing country Spain
    Document type Case Reports
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2021.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Assesment, impact and management of moderate and severe duodenopancreatectomy complications.

    Pastor-Peinado, Paula / Ocaña, Juan / Lobo, Eduardo / Fernández-Cebrían, José María / Sanjuanbenito, Alfonso

    Cirugia espanola

    2021  

    Title translation Análisis, impacto y manejo de las complicaciones moderadas y graves asociadas a la duodenopancreatectomía cefálica.
    Language Spanish
    Publishing date 2021-05-31
    Publishing country Spain
    Document type Case Reports
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.ciresp.2021.04.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Impact of Standard Versus Low Pneumoperitoneum Pressure on Peritoneal Environment in Laparoscopic Cholecystectomy. Randomized Clinical Trial.

    Serrano, Ana Belén / Díaz-Cambronero, Óscar / Montiel, María / Molina, José / Núñez, Mónica / Mendía, Elena / Mané, María Nuria / Lisa, Eduardo / Martínez-Botas, Javier / Gómez-Coronado, Diego / Gaetano, Andrea / Casarejos, María José / Gómez, Ana / Sanjuanbenito, Alfonso

    Surgical laparoscopy, endoscopy & percutaneous techniques

    2024  Volume 34, Issue 1, Page(s) 1–8

    Abstract: Background: High CO 2 pneumoperitoneum pressure during laparoscopy adversely affects the peritoneal environment. This study hypothesized that low pneumoperitoneum pressure may be linked to less peritoneal damage and possibly to better clinical outcomes.! ...

    Abstract Background: High CO 2 pneumoperitoneum pressure during laparoscopy adversely affects the peritoneal environment. This study hypothesized that low pneumoperitoneum pressure may be linked to less peritoneal damage and possibly to better clinical outcomes.
    Materials and methods: One hundred patients undergoing scheduled laparoscopic cholecystectomy were randomized 1:1 to low or to standard pneumoperitoneum pressure. Peritoneal biopsies were performed at baseline time and 1 hour after peritoneum insufflation in all patients. The primary outcome was peritoneal remodeling biomarkers and apoptotic index. Secondary outcomes included biomarker differences at the studied times and some clinical variables such as length of hospital stay, and quality and safety issues related to the procedure.
    Results: Peritoneal IL6 after 1 hour of surgery was significantly higher in the standard than in the low-pressure group (4.26±1.34 vs. 3.24±1.21; P =0.001). On the contrary, levels of connective tissue growth factor and plasminogen activator inhibitor-I were higher in the low-pressure group (0.89±0.61 vs. 0.61±0.84; P =0.025, and 0.74±0.89 vs. 0.24±1.15; P =0.028, respectively). Regarding apoptotic index, similar levels were found in both groups and were 44.0±10.9 and 42.5±17.8 in low and standard pressure groups, respectively. None of the secondary outcomes showed differences between the 2 groups.
    Conclusions: Peritoneal inflammation after laparoscopic cholecystectomy is higher when surgery is performed under standard pressure. Adhesion formation seems to be less in this group. The majority of patients undergoing surgery under low pressure were operated under optimal workspace conditions, regardless of the surgeon's expertise.
    MeSH term(s) Humans ; Peritoneum/surgery ; Cholecystectomy, Laparoscopic/adverse effects ; Cholecystectomy, Laparoscopic/methods ; Pneumoperitoneum/etiology ; Insufflation/adverse effects ; Insufflation/methods ; Laparoscopy/methods ; Pneumoperitoneum, Artificial/adverse effects ; Pneumoperitoneum, Artificial/methods
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1475108-2
    ISSN 1534-4908 ; 1530-4515 ; 1051-7200
    ISSN (online) 1534-4908
    ISSN 1530-4515 ; 1051-7200
    DOI 10.1097/SLE.0000000000001244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Surgery of pancreatic metastasis from renal cell carcinoma.

    Vilar Tabanera, Alberto / Muñoz Muñoz, Paula / Molina Villar, José Manuel / Gajate, Pablo / Sanjuanbenito, Alfonso

    Cirugia espanola

    2020  

    Title translation Cirugía en las metástasis pancreáticas por carcinoma renal.
    Language Spanish
    Publishing date 2020-12-12
    Publishing country Spain
    Document type Case Reports
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.ciresp.2020.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The Spanish Familial Pancreatic Cancer Registry (PANGENFAM): a decade follow-up of individuals at high-risk for pancreatic cancer.

    Earl, Julie / Fuentes, Raquel / Sanchez, María E Castillo / de Paredes, Ana García García / Muñoz, María / Sanjuanbenito, Alfonso / Lobo, Eduardo / Caminoa, Alejandra / Rodríguez, Mercedes / Barreto, Emma / López, Jorge Villalón / Ruz-Caracuel, Ignacio / Durán, Sergio López / Olcina, José Ramón Foruny / Sánchez, Bárbara Luna / Páez, Sonia Camaño / Torres, Ana / Blázquez, Javier / Sequeros, Enrique Vázquez /
    Carrato, Alfredo

    Familial cancer

    2024  

    Abstract: The Spanish Familial Pancreatic Cancer Registry (PANGENFAM) was established in 2009 and aims to characterize the genotype and phenotype of familial pancreatic cancer (FPC). Furthermore, an early detection screening program for pancreatic ductal ... ...

    Abstract The Spanish Familial Pancreatic Cancer Registry (PANGENFAM) was established in 2009 and aims to characterize the genotype and phenotype of familial pancreatic cancer (FPC). Furthermore, an early detection screening program for pancreatic ductal adenocarcinoma (PDAC) is provided to healthy high-risk individuals from FPC and hereditary pancreatic cancer families (first-degree relatives). This article describes our experience over the last 10 years in high-risk screening. Hereditary and familial pancreatic cancer families were identified through the oncology and gastroenterology units. High-risk individuals underwent annual screening with endoscopic ultrasound (EUS) and magnetic resonance (MRI) from age 40 or 10 years younger than the youngest affected family member. Results: PANGENFAM has enrolled 290 individuals from 143 families, including 52 PDAC cases and 238 high-risk individuals. All high-risk individuals eligible for screening were offered to enter the surveillance program, with 143 currently participating. Pancreatic abnormalities were detected in 94 individuals (median age 53 years (29-83), with common findings including cystic lesions and inhomogeneous parenchyma. Imaging test concordance was 66%. Surgical intervention was performed in 4 high-risk individuals following highly suspicious lesions detected by imaging. PANGENFAM is a valuable resource for science innovation, such as biobanking, with clinical and imaging data available for analysis. For high-risk families, it may offer a potential for early diagnosis. Collaboration with other national and international registries is needed to increase our understanding of the disease biology and to standardize criteria for inclusion and follow-up, optimizing cost-effectiveness and efficacy.
    Language English
    Publishing date 2024-05-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1502496-9
    ISSN 1573-7292 ; 1389-9600
    ISSN (online) 1573-7292
    ISSN 1389-9600
    DOI 10.1007/s10689-024-00388-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: C-reactive protein postoperative values to predict clinically relevant postoperative pancreatic fistula after distal pancreatectomy.

    Juez, Luz Divina / Payno, Elena / de Vicente, Irene / Lisa, Eduardo / Molina, José Manuel / Lobo Martínez, Eduardo / Fernández Cebrián, José María / Sanjuanbenito, Alfonso

    Revista espanola de enfermedades digestivas

    2022  Volume 115, Issue 7, Page(s) 362–367

    Abstract: Introduction: despite significant medical and technological advances, the incidence of postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) is reported to be between 3-45 %. The main objective of this study was to analyze the early ... ...

    Abstract Introduction: despite significant medical and technological advances, the incidence of postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) is reported to be between 3-45 %. The main objective of this study was to analyze the early post-surgical risk factors for developing POPF after DP.
    Material and methods: a retrospective observational study was performed on a prospective basis of patients undergoing DP in a tertiary hospital from January 2011 to December 2021. Sociodemographic, preoperative analytical, tumor-related and postoperative complications variables were analyzed.
    Results: of the 52 patients analyzed, 71.8 % of the sample had postoperative drains amylase elevation. However, 25.7 % of the total had grade-B and/or grade-C POPF. Univariate logistic regression with the variables studied showed the following as risk factors for B-C or clinically relevant POPF: amylase values in drainage at the 5th postoperative day (POD) (p = 0.097; 1.01 [1-1.01]), preoperative BMI (p = 0.015; 1.27 [1.04-1.55]) and C-reactive protein (CRP) value at the 3rd POD (p = 0.034; 1.01 [1.01-1.02]). The ROC curve of CRP value at the 3rd POD showed an area under the curve of 0.764 (95 % CI: 0.6-0.93) and the best cut-off point was 190 mg/l (sensitivity 89 % and specificity 67 %).
    Conclusions: CRP value at the 3rd POD is a predictive factor for POPF after DP. Early detection of patients at risk of POPF based on these characteristics could have an impact on their postoperative management.
    MeSH term(s) Humans ; Pancreatectomy/adverse effects ; Pancreatic Fistula/diagnosis ; Pancreatic Fistula/epidemiology ; Pancreatic Fistula/etiology ; C-Reactive Protein ; Prospective Studies ; Pancreaticoduodenectomy/adverse effects ; Risk Factors ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Postoperative Complications/epidemiology ; Drainage/adverse effects ; Amylases/metabolism ; Retrospective Studies
    Chemical Substances C-Reactive Protein (9007-41-4) ; Amylases (EC 3.2.1.-)
    Language English
    Publishing date 2022-06-23
    Publishing country Spain
    Document type Observational Study ; Journal Article
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    DOI 10.17235/reed.2022.8795/2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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