LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU="Sankar, Jishnu"
  2. AU="Yahagi, Naohisa"
  3. AU=Pinho Juliana
  4. AU="Brennan, Anna"
  5. AU="Lee, Theresa M"
  6. AU="Chunqing Ou"
  7. AU="Gwynn, Simon"
  8. AU="Holper, Sarah"
  9. AU="Haider, Farag Ibrahim"
  10. AU="Rice, Jordin L"
  11. AU="Gong, Xingguo"
  12. AU=Rother Magdalena B.
  13. AU="Petrov, Ksenia"
  14. AU="Rijneveld, R"
  15. AU=Lopez-Martinez Briceida
  16. AU=Astone Pia
  17. AU="Amaral, V"

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: Pore-forming proteins and their role in cancer and inflammation: Mechanistic insights and plausible druggable targets.

    Sankar, Jishnu / Arora, Sahil / Joshi, Gaurav / Kumar, Raj

    Chemico-biological interactions

    2022  Volume 366, Page(s) 110127

    Abstract: Perforin is a granular effector pore-forming protein formed in NK cells and Cytotoxic T lymphocytes. These cytotoxic proteins are part of the first-line immune defense in the human body. They ensure apoptosis of pathogen-infected cells or tumor cells in ... ...

    Abstract Perforin is a granular effector pore-forming protein formed in NK cells and Cytotoxic T lymphocytes. These cytotoxic proteins are part of the first-line immune defense in the human body. They ensure apoptosis of pathogen-infected cells or tumor cells in the human body. Activation of receptors on NK cell or T cell triggers secondary proteins in these cells. Further, it leads to Ca
    MeSH term(s) Granzymes/metabolism ; Humans ; Inflammation ; Insulins ; Neoplasms/drug therapy ; Perforin ; Phosphatidylinositol 3-Kinases ; Pore Forming Cytotoxic Proteins/metabolism
    Chemical Substances Insulins ; Pore Forming Cytotoxic Proteins ; Perforin (126465-35-8) ; Granzymes (EC 3.4.21.-)
    Language English
    Publishing date 2022-08-30
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 218799-1
    ISSN 1872-7786 ; 0009-2797
    ISSN (online) 1872-7786
    ISSN 0009-2797
    DOI 10.1016/j.cbi.2022.110127
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 686: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Identification and optimization of pyridine carboxamide-based scaffold as a drug lead for

    Singh, Padam / Kumar, Arun / Sharma, Pankaj / Chugh, Saurabh / Kumar, Ashish / Sharma, Nidhi / Gupta, Sonu / Singh, Manisha / Kidwai, Saqib / Sankar, Jishnu / Taneja, Neha / Kumar, Yashwant / Dhiman, Rohan / Mahajan, Dinesh / Singh, Ramandeep

    Antimicrobial agents and chemotherapy

    2024  Volume 68, Issue 2, Page(s) e0076623

    Abstract: New drugs with novel mechanisms of action are urgently needed to tackle the issue of drug-resistant tuberculosis. Here, we have performed phenotypic screening using the Pathogen Box library obtained from the Medicines for Malaria Venture ... ...

    Abstract New drugs with novel mechanisms of action are urgently needed to tackle the issue of drug-resistant tuberculosis. Here, we have performed phenotypic screening using the Pathogen Box library obtained from the Medicines for Malaria Venture against
    MeSH term(s) Mice ; Animals ; Mycobacterium tuberculosis ; Antitubercular Agents/pharmacology ; Mycobacterium bovis ; Isoniazid ; Tuberculosis/prevention & control
    Chemical Substances Antitubercular Agents ; Isoniazid (V83O1VOZ8L)
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.00766-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 809: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Einzelsignatur: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top