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Article ; Online: The ABCs of personalized incremental dialysis start, Le Mans style.

Torreggiani, Massimo / Fois, Antioco / Samoreau, Clement / Santagati, Giulia / Piccoli, Giorgina Barbara

2022 Volume 35, Issue 9, Page(s) 2417–2423

Abstract: Thrice weekly hemodialysis (HD) is considered the standard of care for patients with end-stage chronic kidney disease (CKD) on extracorporeal renal replacement therapy. However, recent evidence has shown that up to one third of patients start dialysis ... ...

Abstract	Thrice weekly hemodialysis (HD) is considered the standard of care for patients with end-stage chronic kidney disease (CKD) on extracorporeal renal replacement therapy. However, recent evidence has shown that up to one third of patients start dialysis with a residual kidney function that could allow a reduced frequency/dialysis dose. Interest towards HD schedules other than thrice weekly and the lessons learned from peritoneal dialysis, in addition to growing attention to patients' quality of life, have promoted renewed attention towards incremental HD (iHD). iHD comprises once and twice weekly schedules, makes it possible to soften the "dialysis shock" at the inception of therapy and is patient-friendly. Moreover, it might contribute to preserving residual kidney function longer. Nevertheless, iHD is performed differently in different settings and no guidelines exist on this subject. Taking advantage of the experience accrued with regard to the treatment of advanced CKD both in the outpatient clinic and in the dialysis unit in Le Mans, where two thirds of incident HD patients start in an incremental way, we aimed to present the practical aspects of iHD and discuss its advantages and drawbacks.
MeSH term(s)	Male ; Humans ; Renal Dialysis ; Quality of Life ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/therapy ; Peritoneal Dialysis ; Ethnicity ; Disease Progression
Language	English
Publishing date	2022-11-18
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1093991-x
ISSN	1724-6059 ; 1120-3625 ; 1121-8428
ISSN (online)	1724-6059
ISSN	1120-3625 ; 1121-8428
DOI	10.1007/s40620-022-01507-6
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Article ; Online: Knowledge, attitudes, and behaviors of parents towards varicella and its vaccination.

Vezzosi, Luigi / Santagati, Gabriella / Angelillo, Italo F

BMC infectious diseases

2017 Volume 17, Issue 1, Page(s) 172

Abstract: Background: The aims of this cross-sectional survey were to examine the knowledge, the attitudes, and the behavior regarding the varicella infection and its vaccination and to get insight into their determinants among parents of children in Italy.: ... ...

Abstract	Background: The aims of this cross-sectional survey were to examine the knowledge, the attitudes, and the behavior regarding the varicella infection and its vaccination and to get insight into their determinants among parents of children in Italy. Methods: From May to June 2015 in the geographic area of Naples (Italy) a random sample of 675 parents of children aged 4-7 years received a self-administered anonymous questionnaire about socio-demographic characteristics, knowledge, attitudes, and behaviors towards varicella and its vaccination. Results: A total of 414 parents responded to the questionnaire, for a response rate of 61.3%. A history of varicella was reported in 163 children (39.6%). Only 26.6% parents knew that the vaccine was available and the number of doses and this knowledge was significantly higher in those who had a university degree, in those who had received information on the vaccination from a health care provider, and in those who had vaccinated their child. The perceived utility towards vaccination had a mean value of 5.7. The positive attitude towards the utility of the vaccination was higher in parents with a level of education not higher than middle school, in those who had vaccinated their child, in those who considered the varicella a dangerous disease, and in those who had received information from a health care provider. More than one-third had vaccinated their child. Immunization was more frequent in parents who had knowledge about the vaccination, who beliefs that the immunization was useful, who believed that the disease was not dangerous, and who had not a history of varicella among their children. Conclusions: Educational programs are needed among parents as support to improve knowledge about vaccination and immunization coverage.
MeSH term(s)	Adolescent ; Adult ; Chickenpox/prevention & control ; Chickenpox/psychology ; Chickenpox Vaccine ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Italy ; Male ; Middle Aged ; Parents/psychology ; Surveys and Questionnaires ; Vaccination/psychology ; Young Adult
Chemical Substances	Chickenpox Vaccine
Language	English
Publishing date	2017-02-27
Publishing country	England
Document type	Journal Article
ISSN	1471-2334
ISSN (online)	1471-2334
DOI	10.1186/s12879-017-2247-6
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Article ; Online: Violence Experience among Immigrants and Refugees: A Cross-Sectional Study in Italy.

Napolitano, Francesco / Gualdieri, Luciano / Santagati, Gabriella / Angelillo, Italo Francesco

BioMed research international

2018 Volume 2018, Page(s) 7949483

Abstract: The objectives of this cross-sectional investigation among a random sample of immigrants and refugees in Italy were to gain an insight into the extent and type of the episodes of violence and to assess their association with different characteristics. ... ...

Abstract	The objectives of this cross-sectional investigation among a random sample of immigrants and refugees in Italy were to gain an insight into the extent and type of the episodes of violence and to assess their association with different characteristics. Data was collected from September 2016 to July 2017 using a face-to-face structured interview. A total of 503 subjects participated. Overall, 46.5% and 40% of the sample reported having experienced some form of violence in Italy at least once since they arrived and during the last 12 months. Psychological violence was the most common form experienced by 53.2% of the participants, 40.3% experiencing physical violence, 18.9% economic violence, and only 6.5% intimate partner violence. The risk of experiencing at least one form of violence in the last 12 months in Italy was more likely to occur among immigrants who have been in Italy much longer and less likely in those who lived in a camp. The number of episodes of violence experienced since they arrived in Italy was significantly higher in female, in those who have been in Italy much longer and in those who had experienced at least one racially discriminatory episode of violence, whereas those with middle and high school or above educational level and those who did not experience psychological consequences of the violence had experienced a lower number of episodes. These results must be used to strengthen interventions and policies aimed at preventing violence among this population.
MeSH term(s)	Adolescent ; Adult ; Aged ; Cross-Sectional Studies ; Emigrants and Immigrants/psychology ; Female ; Humans ; Italy ; Male ; Middle Aged ; Physical Abuse/psychology ; Refugees/psychology
Language	English
Publishing date	2018-09-23
Publishing country	United States
Document type	Journal Article ; Observational Study ; Randomized Controlled Trial
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2018/7949483
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Article ; Online: Knowledge, attitudes, and practice regarding medication use in pregnant women in Southern Italy.

Navaro, Monica / Vezzosi, Luigi / Santagati, Gabriella / Angelillo, Italo Francesco

PloS one

2018 Volume 13, Issue 6, Page(s) e0198618

Abstract: The study assessed knowledge, attitudes, and medication use of a random sample of pregnant women attending outpatient Gynecology and Obstetrics clinics at randomly selected public General and Teaching hospitals in Naples, Italy. A total of 503 women ... ...

Abstract	The study assessed knowledge, attitudes, and medication use of a random sample of pregnant women attending outpatient Gynecology and Obstetrics clinics at randomly selected public General and Teaching hospitals in Naples, Italy. A total of 503 women participated. Those more likely to know that a pregnant woman with chronic condition must discuss whether or not to take a medication with the physician were Italian, aged 31-40 years, employed, with no history of abortion, having had a medical problem within the previous year, with a better self-perceived health status, who knew how to use medications during pregnancy, and who needed information on medications. The knowledge of the potential risk of using non-prescribed medications during pregnancy was significantly higher in employed women, who received information from physicians, who knew how to use medications during pregnancy, and who knew the possible damages related to medications use. More than half had used at least one medication. Those aged 26-35 years, Italian, non-graduated, in the third trimester, having had a medical problem within the previous year, with a risky pregnancy, and with a knowledge that women with chronic condition must discuss whether or not to take a medication with the physician were more likely to use medication. Less than half had used medication without a physician's advice. Those who were more likely to self-medicate were older, Italian, multiparous, with no history of abortion, who knew that women with chronic condition must discuss whether or not to take a medication with the physician, who did not know the potential risk of using non-prescribed medication during pregnancy, who had used prescribed medication during pregnancy, and who needed information about medications. Educational programs for women about medication use are important to increase their knowledge of the potential risks to the pregnant women and the unborn child in order to reduce self-medication.
MeSH term(s)	Abnormalities, Drug-Induced/prevention & control ; Adolescent ; Adult ; Cross-Sectional Studies ; Drug Therapy/psychology ; Drug Utilization/statistics & numerical data ; Female ; Health Behavior ; Health Knowledge, Attitudes, Practice ; Health Services Needs and Demand ; Humans ; Italy ; Parity ; Patient Education as Topic ; Physician-Patient Relations ; Pregnancy/psychology ; Risk ; Self Medication/psychology ; Self Medication/statistics & numerical data ; Surveys and Questionnaires ; Young Adult
Language	English
Publishing date	2018-06-19
Publishing country	United States
Document type	Journal Article ; Multicenter Study
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0198618
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Article ; Online: Knowledge and attitudes toward HPV infection and vaccination among immigrants and refugees in Italy.

Napolitano, Francesco / Gualdieri, Luciano / Santagati, Gabriella / Angelillo, Italo Francesco

Vaccine

2018 Volume 36, Issue 49, Page(s) 7536–7541

Abstract: Background: The objectives of the present cross-sectional study were to investigate the level of knowledge and attitudes regarding Human papillomavirus (HPV) infection and its vaccination and to understand the impact of different determinants among ... ...

Abstract	Background: The objectives of the present cross-sectional study were to investigate the level of knowledge and attitudes regarding Human papillomavirus (HPV) infection and its vaccination and to understand the impact of different determinants among immigrants and refugees in Italy. Methods: Between September 2016 and March 2018, a total of 519 potential participants were randomly recruited. The information was collected through a questionnaire administered by two researchers. Results: Only 15.9% reported that they had heard of HPV infection before completing the survey and 83.8% of them were aware that the infection could be transmitted through sexual intercourses, 32.3% that it can lead to cervical cancer, 22% to warts, 16.2% to penile cancer, 13.2% to oral cancer, 39.7% that cervical cancer is a very severe disease, 47.1% that receiving the vaccine could protect against the infection, and 44.1% that a vaccine against HPV is available in Italy. Females, those who originated from Eastern Europe, Asia and South America, those who lived in a house compared to those who lived in a street, and those who had 1-10 years and 11 or more years of education compared to those illiterate were more likely to have heard about the HPV infection before completing the survey. Only 3 participants (0.7%) received the HPV vaccination. Out of the unvaccinated who had heard of HPV, 50.7% and 59% of those between the ages of 12 and 26 and of those who had at least one child aged 12-26 years, were willing to receive vaccination for themselves as well as their children. Conclusion: The results underscored the necessity to develop health education and promotion aimed at improving the knowledge and vaccination practice in immigrants and refugees.
MeSH term(s)	Adolescent ; Adult ; Aged ; Cross-Sectional Studies ; Emigrants and Immigrants/psychology ; Female ; Health Education ; Health Knowledge, Attitudes, Practice ; Humans ; Italy ; Logistic Models ; Male ; Middle Aged ; Papillomavirus Infections/prevention & control ; Papillomavirus Vaccines/therapeutic use ; Patient Acceptance of Health Care ; Refugees/psychology ; Surveys and Questionnaires ; Uterine Cervical Neoplasms/prevention & control ; Vaccination/psychology ; Young Adult
Chemical Substances	Papillomavirus Vaccines
Language	English
Publishing date	2018-10-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2018.10.050
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Article ; Online: Unintentional Injuries in Children Up to Six Years of Age and Related Parental Knowledge, Attitudes, and Behaviors in Italy.

Santagati, Gabriella / Vezzosi, Luigi / Angelillo, Italo F

The Journal of pediatrics

2016 Volume 177, Page(s) 267–272.e2

Abstract: Objectives: To describe risk factors associated with unintentional injuries among children aged <6 years and to examine parents' level of knowledge, attitudes, and behaviors about pediatric injuries and related preventive measures.: Study design: A ... ...

Abstract	Objectives: To describe risk factors associated with unintentional injuries among children aged <6 years and to examine parents' level of knowledge, attitudes, and behaviors about pediatric injuries and related preventive measures. Study design: A cross-sectional survey was conducted between May and July 2015 on a random sample of 794 parents of 3- to 6-year-old children through a self-administered anonymous questionnaire. Results: A total of 409 parents participated. Two-thirds of the children had experienced at least 1 unintentional injury in the previous 12 months. More than one-half of these children were boys. The leading cause was falls; the injuries occurred mainly at home, and only 9.2% were brought for attention to an emergency department. Parents who did not believe that it is possible to prevent unintentional injuries were more likely to have had a child injured. Approximately 70% of respondents were aware of security measures to prevent pediatric injuries, and this knowledge was more prevalent in older parents and in those with at least a college level of education compared with those with a middle school education. The perceived utility of education about preventive measures of pediatric injuries had a mean value of 8.9 on a Likert scale of 1-10 (1, not useful, to 10, very useful) and was significantly higher in mothers. Conclusions: This study highlights a clear need for public health educational programs for parents regarding prevention of unintentional injuries in children as a valuable tool to increase safety and injury prevention and to reduce risks, because the majority of such injuries occur at home.
MeSH term(s)	Adolescent ; Adult ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Italy/epidemiology ; Male ; Middle Aged ; Parents ; Risk Factors ; Self Report ; Wounds and Injuries/epidemiology ; Young Adult
Language	English
Publishing date	2016-08-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	3102-1
ISSN	1097-6833 ; 0022-3476
ISSN (online)	1097-6833
ISSN	0022-3476
DOI	10.1016/j.jpeds.2016.06.083
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Article ; Online: Full normalization of severe hypertension after parathryoidectomy - a case report and systematic review.

Sofronie, Andreea Corina / Kooij, Isabelle / Bursot, Claude / Santagati, Giulia / Coindre, Jean-Philippe / Piccoli, Giorgina Barbara

BMC nephrology

2018 Volume 19, Issue 1, Page(s) 112

Abstract: Background: Although the relationship between hyperparathyroidism and hypertension has been described for decades, the role of hyperparathyroidism in hypertension in dialysis is still unclear. Following the case of a severely hypertensive dialysis ... ...

Abstract	Background: Although the relationship between hyperparathyroidism and hypertension has been described for decades, the role of hyperparathyroidism in hypertension in dialysis is still unclear. Following the case of a severely hypertensive dialysis patient, in which parathyroidectomy (PTX) corrected the metabolic imbalance and normalized blood pressure (BP), we tried to contextualize our observation with a systematic review of the recent literature on the effect of PTX on BP. Case presentation: A dialysis patient, aged 19 years at the time of this report, with chronic kidney disease (CKD) from childhood; he was an early-preterm baby with very low birth weight (910 g), and is affected by a so-far unidentified familial nephropathy. He started dialysis in emergency at the age of 17. Except for low-dose Bisoprolol, he refused all chronic medication; hypertension (165-200/90-130 mmHg) did not respond to attainment of dry weight (Kt/V > 1.7; BNP 70-200 pg/ml pre-dialysis). He underwent subtotal PTX 1 year after dialysis start; after PTX, his blood pressure stabilized in the 100-140/50-80 range, and is normal without treatment 5 months later. Conclusion: Our patient has some peculiar features: he is young, has a non-immunologic disease, poor compliance to drug therapy, excellent dialysis efficiency. His lack of compliance allows observing the effect of PTX on BP without pharmacologic interference. The prompt, complete and long-lasting BP normalization led us to systematic review the current literature (Pubmed, Embase, Cochrane Collaboration 2000-2016) retrieving 8 case series (194 cases), and one case report (3 patients). The meta-analysis showed a significant, albeit moderate, improvement in BP after PTX (difference: systolic BP -8.49 (CI 2.21-14.58) mmHg; diastolic BP -4.14 (CI 1.45-6.84) mmHg); analysis is not fully conclusive due to lack of information on anti-hypertensive agents. The 3 cases reported displayed a sharp reduction in BP after PTX. In summary, PTX may have a positive influence on BP control, and may result in complete correction or even hypotension in some patients. The potential clinical relevance of this relationship warrants prospective large-scale studies.
MeSH term(s)	Humans ; Hypertension/complications ; Hypertension/diagnostic imaging ; Hypertension/surgery ; Hyperthyroidism/complications ; Hyperthyroidism/diagnostic imaging ; Hyperthyroidism/surgery ; Male ; Parathyroidectomy/trends ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diagnostic imaging ; Renal Insufficiency, Chronic/surgery ; Severity of Illness Index ; Young Adult
Language	English
Publishing date	2018-05-11
Publishing country	England
Document type	Case Reports ; Journal Article ; Systematic Review
ZDB-ID	2041348-8
ISSN	1471-2369 ; 1471-2369
ISSN (online)	1471-2369
ISSN	1471-2369
DOI	10.1186/s12882-018-0900-y
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Article ; Online: Primary care pediatricians' attitudes and practice towards HPV vaccination: A nationwide survey in Italy.

Napolitano, Francesco / Navaro, Monica / Vezzosi, Luigi / Santagati, Gabriella / Angelillo, Italo Francesco

PloS one

2018 Volume 13, Issue 3, Page(s) e0194920

Abstract: This national online cross-sectional survey in Italy assessed primary care pediatricians' (PCPs) attitudes and practices regarding Human papillomavirus (HPV) vaccination and the contribution of several characteristics. The questionnaire was distributed ... ...

Abstract	This national online cross-sectional survey in Italy assessed primary care pediatricians' (PCPs) attitudes and practices regarding Human papillomavirus (HPV) vaccination and the contribution of several characteristics. The questionnaire was distributed from September 2016 to June 2017 to a random sample of 640 PCPs by email via an internet-link leading to a web-based survey platform (Lime Survey). Only 18.4% of PCPs always recommend the HPV vaccine to 11-12 year old boys. PCPs with longer practice activity, working in solo practice, always recommended the HPV vaccine to 11-12 year old girls, and believed that the vaccine was effective for boys were more likely to always recommend the HPV vaccine. PCPs working in a Region where the vaccination was actively recommended and provided free of charge to 11-12 year old boys had higher odds of recommending vaccination. More than two thirds of PCPs (77.4%) always recommend the HPV vaccine to 11-12 year old girls. PCPs who believed that the vaccine was effective for girls and safe in both boys and girls, who always talk with patients of 11-18 years or their parents about HPV infection and vaccination, and who obtain vaccine information from scientific journals were more likely to always recommend the vaccine. PCPs should employ evidence-based educational strategies in order to achieve a better coverage and to reduce the morbidities and mortality of diseases associated with HPV.
MeSH term(s)	Adult ; Aged ; Attitude to Health ; Child ; Female ; Humans ; Italy ; Male ; Middle Aged ; Papillomavirus Infections/prevention & control ; Papillomavirus Vaccines ; Pediatricians/psychology ; Primary Health Care ; Surveys and Questionnaires ; Vaccination/psychology
Chemical Substances	Papillomavirus Vaccines
Language	English
Publishing date	2018
Publishing country	United States
Document type	Journal Article
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0194920
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Article ; Online: Spontaneously Low Protein Intake in Elderly CKD Patients: Myth or Reality? Analysis of Baseline Protein Intake in a Large Cohort of Patients with Advanced CKD.

Torreggiani, Massimo / Fois, Antioco / Moio, Maria Rita / Chatrenet, Antoine / Mazé, Béatrice / Lippi, Françoise / Vigreux, Jerome / Beaumont, Coralie / Santagati, Giulia / Paulin, Noemi / Piccoli, Giorgina Barbara

Nutrients

2021 Volume 13, Issue 12

Abstract: The recent guidelines on nutritional management of chronic kidney disease (CKD) advise a reduction in protein intake as early as CKD stage 3, regardless of age, to slow kidney function impairment. However, since elderly patients are usually considered as ...

Abstract	The recent guidelines on nutritional management of chronic kidney disease (CKD) advise a reduction in protein intake as early as CKD stage 3, regardless of age, to slow kidney function impairment. However, since elderly patients are usually considered as having a spontaneously reduced protein intake, nutritional interventions to reduce protein intake are often considered futile. This study aimed to assess the baseline protein intake of elderly CKD patients referred for nephrology care, and explore the need for dietary evaluations, focusing on the current recommendations for protein restriction in CKD. This is an observational study of CKD patients followed in the unit dedicated to advanced CKD patients in Le Mans, France. Patients with stages 3 to 5 not on dialysis were included. All patients were evaluated by an expert dietician to assess their baseline protein intake, whenever possible on the basis of a 7-days diet journal; when this was not available, dietary recall or analysis of delivered meals was employed. Demographic characteristics, underlying kidney disease, Charlson Comorbidity Index (CCI), Malnutrition-Inflammation Score (MIS), Subjective Global Assessment (SGA) and clinical and laboratory data were recorded. Between 15 November 2017 and 31 December 2020, 436 patients were evaluated in the unit. Their age distribution was as follows: "young": <60 (
MeSH term(s)	Age Factors ; Aged ; Aged, 80 and over ; Cohort Studies ; Comorbidity ; Diet, Protein-Restricted/methods ; Dietary Proteins/administration & dosage ; Female ; Follow-Up Studies ; France/epidemiology ; Humans ; Male ; Malnutrition/etiology ; Malnutrition/prevention & control ; Middle Aged ; Nutrition Therapy/methods ; Patient Acuity ; Renal Insufficiency, Chronic/diet therapy ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/mortality ; Survival Rate
Chemical Substances	Dietary Proteins
Language	English
Publishing date	2021-12-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13124371
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Article ; Online: New Intravenous Calcimimetic Agents: New Options, New Problems. An Example on How Clinical, Economical and Ethical Considerations Affect Choice of Treatment.

Piccoli, Giorgina Barbara / Trabace, Tiziana / Chatrenet, Antoine / Carranza de La Torre, Carlos Alberto / Gendrot, Lurlinys / Nielsen, Louise / Fois, Antioco / Santagati, Giulia / Saulnier, Patrick / Panocchia, Nicola

International journal of environmental research and public health

2020 Volume 17, Issue 4

Abstract: Background: Dialysis treatment is improving, but several long-term problems remain unsolved, including metabolic bone disease linked to chronic kidney disease (CKD-MBD). The availability of new, efficacious but expensive drugs (intravenous calcimimetic ... ...

Abstract	Background: Dialysis treatment is improving, but several long-term problems remain unsolved, including metabolic bone disease linked to chronic kidney disease (CKD-MBD). The availability of new, efficacious but expensive drugs (intravenous calcimimetic agents) poses ethical problems, especially in the setting of budget limitations. Methods: Reasons of choice, side effects, biochemical trends were discussed in a cohort of 15 patients (13% of the dialysis population) who stared treatment with intravenous calcimimetics in a single center. All patients had previously been treated with oral calcimimetic agents; dialysis efficacy was at target in 14/15; hemodiafiltration was employed in 10/15. Median Charlson Comorbidity Index was 8. The indications were discussed according to the principlist ethics (beneficience, non maleficience, justice and autonomy). Biochemical results were analyzed to support the clinical-ethical choices. Results: In the context of a strict clinical and biochemical surveillance, the lack of side effects ensured "non-maleficence"; efficacy was at least similar to oral calcimimetic agents, but tolerance was better. Autonomy was respected through a shared decision-making model; all patients appreciated the reduction of the drug burden, and most acknowledged better control of their biochemical data. The ethical conflict resides in the balance between the clinical "beneficience, non-maleficience" advantage and "justice" (economic impact of treatment, potentially in attrition with other resources, since the drug is expensive and included in the dialysis bundle). The dilemma is more relevant when a patient's life expectancy is short (economic impact without clear clinical advantages), or when non-compliance is an issue (unclear advantage if the whole treatment is not correctly taken). Conclusions: In a context of person-centered medicine, autonomy, beneficence and non-maleficence should weight more than economic justice. While ethical discussions are not aimed at finding "the right answer" but asking "the right questions", this example can raise awareness of the importance of including an ethical analysis in the choice of "economically relevant" drugs.
MeSH term(s)	Aged ; Beneficence ; Calcimimetic Agents/administration & dosage ; Female ; Humans ; Male ; Personal Autonomy ; Renal Dialysis ; Social Justice
Chemical Substances	Calcimimetic Agents
Language	English
Publishing date	2020-02-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph17041238
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