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  1. Article: Climate justice and digitalization. A plea to consider broader socio-economic implications of digitalization and climate change. Worldwide, the impacts of global warming and the benefits of climate protection are unfairly distributed. To advance the fair sharing of benefits from digital climate technologies, technological development must be decentralized and rules for competition must be established

    Santarius, Tilman

    Gaia

    2022  Volume 31, Issue 3, Page(s) 146

    Language German ; English
    Document type Article
    ZDB-ID 1114994-2
    ISSN 0940-5550
    Database Current Contents Nutrition, Environment, Agriculture

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    Z 7434: Show issues

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  2. Article ; Online: Does deep cerebral venous engorgement contribute to non-hydrocephalic pineal cysts becoming symptomatic? Some missing links.

    Santarius, Thomas / Pickard, John D

    Brain communications

    2023  Volume 5, Issue 2, Page(s) fcad096

    Abstract: This scientific commentary refers to 'Physiological alterations of pineal recess crowding in symptomatic non-hydrocephalic pineal cysts' by ... ...

    Abstract This scientific commentary refers to 'Physiological alterations of pineal recess crowding in symptomatic non-hydrocephalic pineal cysts' by Eide
    Language English
    Publishing date 2023-03-29
    Publishing country England
    Document type Journal Article
    ISSN 2632-1297
    ISSN (online) 2632-1297
    DOI 10.1093/braincomms/fcad096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Digitalization and sustainability: A systematic literature analysis of ICT for Sustainability research

    Santarius, Tilman / Wagner, Josephin

    Gaia

    2023  Volume 32, Issue S1, Page(s) 21

    Language German ; English
    Document type Article
    ZDB-ID 1114994-2
    ISSN 0940-5550
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

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  4. Article ; Online: An audit of endoscopic third ventriculostomy (ETV) in a regional paediatric neurosurgical centre assessing the accuracy and feasibility of the ETV success score.

    Yordanov, Stefan / Garnett, M R / Santarius, T / Holland, K / Jalloh, I / Jawad Naushahi, M

    Acta neurochirurgica

    2022  Volume 164, Issue 6, Page(s) 1453–1458

    Abstract: Background: Endoscopic third ventriculostomy success score (ETVss) is widely utilised to predict outcomes for ETV. Accurate prediction of success for a procedure is of vital importance both for selecting the optimal management plan and for obtaining ... ...

    Abstract Background: Endoscopic third ventriculostomy success score (ETVss) is widely utilised to predict outcomes for ETV. Accurate prediction of success for a procedure is of vital importance both for selecting the optimal management plan and for obtaining informed consent. Existing literature demonstrates a variety of opinions on the accuracy of the currently utilised ETVss and recommends a range of techniques to reduce the number of subsequent ventriculo-peritoneal (VP)-shunt insertions, prompting the present study.
    Methods: We retrospectively analysed data for ETV cases since 2007 to review success rate in our regional paediatric neurosurgical centre and if the currently utilised ETVss successfully predicted outcomes. Failed ETV cases were defined as any patient who received a VP-shunt at any time following ETV. Data was analysed with MS Excel
    Results: 44 ETVs were performed over 13 years with approximately equal distribution between male and female patients; median age 7 years (IQR 4-13 years). Overall, mean ETVss for these 44 procedures was 78%; actual success rate was 70% with no statistically significant difference between them (p = 0.286; Welch two sample t-test). Accuracy of ETVss varied with pathology: tectal gliomas (mean ETVss 75% and actual success 78%); cerebellar tumours (mean ETVss 85% and actual success 81%); other tumours (mean ETVss 75% and actual success 81%); aqueduct stenosis (mean ETVss 71% and actual success 69%); and other pathologies (mean ETVss 70% and actual success 60%). < 1 month and 1-6 months and 1-10 years and > 10 years contributed equally to the accuracy of ETVss.
    Conclusion: Non-telencephalon tumours and obstruction at the level of the mid-brain are most strongly associated with successful ETV outcome. These findings can be used to modify the currently utilised ETVss to further improve accuracy of outcome prediction. We recommend a modified-ETVss (m-ETVss) and a future larger adequately powered prospective study to validate this.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Feasibility Studies ; Female ; Humans ; Hydrocephalus/pathology ; Hydrocephalus/surgery ; Infant ; Male ; Neuroendoscopy/methods ; Prospective Studies ; Retrospective Studies ; Third Ventricle/pathology ; Third Ventricle/surgery ; Treatment Outcome ; Ventriculostomy/methods
    Language English
    Publishing date 2022-02-25
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-022-05151-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.180: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Customised pre-operative cranioplasty to achieve maximal surgical resection of tumours with osseous involvement-a case series.

    Jain, Swati / Helmy, Adel / Santarius, Thomas / Owen, Nicola / Grieve, Kirsty / Hutchinson, Peter / Timofeev, Ivan

    Acta neurochirurgica

    2024  Volume 166, Issue 1, Page(s) 152

    Abstract: Purpose: Surgical resection with bony margins would be the treatment of choice for tumours with osseous involvement such as meningiomas and metastasis. By developing and designing pre-operative customised 3D modelled implants, the patient can undergo ... ...

    Abstract Purpose: Surgical resection with bony margins would be the treatment of choice for tumours with osseous involvement such as meningiomas and metastasis. By developing and designing pre-operative customised 3D modelled implants, the patient can undergo resection of meningioma and repair of bone defect in the same operation. We present a generalisable method for designing pre-operative cranioplasty in patients to repair the bone defect after the resection of tumours.
    Materials and methods: We included six patients who presented with a tumour that was associated with overlying bone involvement. They underwent placement of customised cranioplasty in the same setting. A customised implant using a pre-operative imaging was designed with a 2-cm margin to allow for any intra-operative requirements for extending the craniectomy.
    Results: Six patients were evaluated in this case series. Four patients had meningiomas, 1 patient had metastatic breast cancer on final histology, and 1 patient was found to have an intra-osseous arteriovenous malformation. Craniectomy based on margins provided by a cutting guide was fashioned. After tumour removal and haemostasis, the cranioplasty was then placed. All patients recovered well post-operatively with satisfactory cosmetic results. No wound infection was reported in our series.
    Conclusion: Our series demonstrate the feasibility of utilising pre-designed cranioplasty for meningiomas and other tumours with osseous involvement. Following strict infection protocols, minimal intra-operative handling/modification of the implant, and close follow-up has resulted in good cosmetic outcomes with no implant-related infections.
    MeSH term(s) Humans ; Plastic Surgery Procedures ; Meningioma/surgery ; Decompressive Craniectomy/methods ; Skull/surgery ; Postoperative Complications/surgery ; Meningeal Neoplasms/surgery ; Retrospective Studies
    Language English
    Publishing date 2024-03-27
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-024-06055-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Intracranial gossypiboma 9 years after intracranial pressure bolt insertion: illustrative case.

    Loh, Ryan T S / Matys, Tomasz / Allinson, Kieren S J / Santarius, Thomas

    Journal of neurosurgery. Case lessons

    2022  Volume 3, Issue 8

    Abstract: Background: Resorbable hemostatic agents left behind postoperatively occasionally result in granulomatous space-occupying lesions known as "gossypibomas." The authors report a case of an intracranial gossypiboma, which is exceedingly rare and frequently ...

    Abstract Background: Resorbable hemostatic agents left behind postoperatively occasionally result in granulomatous space-occupying lesions known as "gossypibomas." The authors report a case of an intracranial gossypiboma, which is exceedingly rare and frequently radiologically indistinguishable from other lesions.
    Observations: A 35-year-old woman presented with a generalized tonic-clonic seizure and subsequent left-sided hemiparesis. Magnetic resonance imaging showed an enhancing lobulated lesion subjacent to a right frontal burr hole, surrounded by vasogenic edema with mass effect and midline shift. Nine years earlier, she had had a triple bolt inserted to monitor intracranial pressure after sustaining a traumatic brain injury. Surgicel was used to control bleeding during insertion. Colocation of the lesion with the position of triple bolt 9 years earlier raised suspicion for gossypiboma. However, the minor nature of the surgery and the length of time since surgery to presentation placed this case well outside the range of cases reported in the literature. The lesion was resected en bloc with no recurrence 18 months later. Histological examination revealed the presence of foreign material. However, given its minute size, confirming its nature was not possible.
    Lessons: The authors show that gossypibomas can occur following a relatively minor procedure and remain clinically and radiologically silent for much longer than previously reported.
    Language English
    Publishing date 2022-02-21
    Publishing country United States
    Document type Journal Article
    ISSN 2694-1902
    ISSN (online) 2694-1902
    DOI 10.3171/CASE21479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Assessing the accuracy of the International Classification of Disease (ICD) framework in the identification of patients with chronic subdural haematoma from hospital records.

    Yordanov, Stefan / Khan, Shuaib / Stubbs, Danial / Davies, Benjamin / Santarius, Thomas / Hutchinson, Peter / Joannides, Alexis

    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland

    2023  Volume 21, Issue 5, Page(s) e271–e278

    Abstract: Background: Chronic subdural hematoma (CSDH) is one of the commonest neurosurgical pathologies with an increasing incidence. Observational studies of routine care have demonstrated high perioperative morbidity and approximately 10% mortality at one year. ...

    Abstract Background: Chronic subdural hematoma (CSDH) is one of the commonest neurosurgical pathologies with an increasing incidence. Observational studies of routine care have demonstrated high perioperative morbidity and approximately 10% mortality at one year. The development, implementation, and evaluation of a potential care framework relies on an accurate and reproducible method of case identification and case ascertainment. With this manuscript, we report on the accuracy of diagnostic ICD codes for identifying patients with CSDH from retrospective electronic data and explore whether basic demographic data could improve the identification of CSDH.
    Methods: Data were collected retrospectively from the hospital administrative system between 2014 and 2018 of all patients coded with either S065 or I620. Analysis of the ICD codes in identifying patients with CSDH diagnosis was calculated using the caret
    Results: A total of 1861 patients were identified. Of these, 189 (10.2%) had a diagnosis of non-traumatic SDH (I620) and 1672 (89.8%) traumatic subdural haematomas (S065). Variables that identified CSDH as a diagnosis on univariate logistic regression included male sex (Odds Ratios (OR) - 1.606 (1.197-2.161), elderly age (OR) - 1.023 (1.015-1.032) per year for age (p < 0.001) and shorter length of hospital stay. Using stepwise regression against AIC the best model to predict CSDH included male sex, older age, and shorter LOS. The calculated sensitivity for identifying CSDH with the model is 88.4% with a specificity of 84.5% and PPV of 87.9%.
    Conclusion: CSDH is a common neurosurgical pathology with increasing incidence and ongoing unmet clinical need. We demonstrate that case ascertainment for research purposes can be improved with the incorporation of additional demographic data but at the expense of significant case exclusion.
    MeSH term(s) Aged ; Humans ; Male ; Hematoma, Subdural, Chronic/diagnosis ; Hematoma, Subdural, Chronic/pathology ; Hematoma, Subdural, Chronic/surgery ; Hospital Records ; International Classification of Diseases ; Length of Stay ; Retrospective Studies ; Female
    Language English
    Publishing date 2023-03-24
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2102927-1
    ISSN 1479-666X
    ISSN 1479-666X
    DOI 10.1016/j.surge.2023.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5756: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Chancen und Grenzen einer ‚3-D-Ökonomie‘ ; Opportunities and limitations of a ‘3-D economy’:

    Santarius, Tilman / Lange, Steffen

    2021  

    Abstract: Digitale Technologien können eine regionale bzw. lokale Produktion durch uneingeschränkten Zugang zu Informationen und Märkten attraktiver und auch kostengünstiger machen. Zugleich ermöglichen digitale Technologien neue Kommunikationsweisen, die mehr ... ...

    Abstract Digitale Technologien können eine regionale bzw. lokale Produktion durch uneingeschränkten Zugang zu Informationen und Märkten attraktiver und auch kostengünstiger machen. Zugleich ermöglichen digitale Technologien neue Kommunikationsweisen, die mehr Mitsprache, offenere Märkte und eine Begegnung von Marktteilnehmenden ‚auf Augenhöhe‘ ermöglichen. In diesem Beitrag leuchten wir die Chancen und Grenzen der Digitalisierung für eine Dezentralisierung und Demokratisierung der Ökonomie aus, veranschaulichen bestehende Potenziale anhand von zahlreichen Fallbeispielen und zeigen deren Beitrag zur ökologischen Nachhaltigkeit auf. Doch wir analysieren auch, dass diesen Potenzialen in der Realität eine historisch beispiellose Konzentration von Marktmacht in der Hand einiger weniger IT-Konzerne gegenübersteht. Nebst den Chancen zeigen wir in diesem Beitrag daher ebenfalls, aufgrund welcher Mechanismen die Digitalisierung der Ökonomie einer Dezentralisierung und Demokratisierung zuwiderlaufen kann. Abschließend stellen wir Perspektiven und Instrumente vor, wie eine ‚3-D-Ökonomie‘ – digital, demokratisch, dezentral – politisch unterstützt werden kann.
    Keywords ddc:650 ; Digitaler Kapitalismus ; Re-Regionalisierung ; Dezentrale Ökonomie ; Wirtschaftsdemokratie ; Postwachstums-Ökonomie ; Degrowth
    Subject code 338
    Language German
    Publisher Berlin, Heidelberg: Springer
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Investigating meso-economic rebound effects: production-side effects and feedback loops between the micro and macro level

    Santarius, Tilman

    Journal of cleaner production. 2016 Oct. 15, v. 134

    2016  

    Abstract: Research on the rebound effect has so far mainly considered ‘micro-economic rebound effects’ at the level of consumers and households, as well as ‘macro-economic rebound effects’ in the sense of energy efficiency-induced economic growth effects. This ... ...

    Abstract Research on the rebound effect has so far mainly considered ‘micro-economic rebound effects’ at the level of consumers and households, as well as ‘macro-economic rebound effects’ in the sense of energy efficiency-induced economic growth effects. This article focuses on an area of rebound research that has not yet received sufficient attention, namely on ‘meso-economic rebound effects’ as production-side and sector-level rebounds. The article summarizes and systematizes reasons why companies generate rebounds, distinguishes market- and sector-level rebounds from macro-economic growth effects, identifies a number of ‘feedback loops’ by which production-side and sector-level rebounds multiply or nullify consumer-side rebound effects, and finally discusses some conclusions on the potential quantitative dimension of production-side rebound effects.
    Keywords business enterprises ; economic development ; energy ; households
    Language English
    Dates of publication 2016-1015
    Size p. 406-413.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2015.09.055
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Die Grenzen der Ressourceneffizienz. Wie technische Produktivitätssteigerungen das Wachstum ankurbeln

    Santarius, Tilman

    Jahrbuch nachhaltige Ökonomie Vol. 5 (2016/17), p. 123-146

    2016  Volume 5, Page(s) 123–146

    Author's details Tilman Santarius
    Language German
    Size Illustrationen
    Publisher Metropolis-Verl
    Publishing place Marburg
    Document type Article
    Note Literaturangaben
    ZDB-ID 2637488-2
    Database ECONomics Information System

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