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Article ; Online: Why are measles and rubella returning in Brazil?

Borges, Lysandro P / Barreto, Marina Dos S / Santos, Ronaldy S / Souza, Jessiane B DE / Silva, Beatriz S DA / Jesus, Pamela C DE / Silva, Deise M R R / Moura, Pedro H M / Santos, Leticia M M Dos / Silva, Eloia E D / Santana, Lucas A DA M

Anais da Academia Brasileira de Ciencias

2023 Volume 95, Issue suppl 2, Page(s) e20230832

MeSH term(s)	Humans ; Infant ; Brazil/epidemiology ; Rubella/epidemiology ; Rubella/prevention & control ; Measles/epidemiology
Language	English
Publishing date	2023-12-01
Publishing country	Brazil
Document type	Letter
ZDB-ID	2046885-4
ISSN	1678-2690 ; 0001-3765
ISSN (online)	1678-2690
ISSN	0001-3765
DOI	10.1590/0001-3765202320230832
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Article ; Online: Celiac trunk stenosis by median arcuate ligament in orthotopic liver transplantation: a potential hidden foe to the biliary tree.

Lazzarotto-da-Silva, Gabriel / Santos, Leticia M / Lucena, Iara R S / Rabolini, Bruno B / Hallal, Celina P / Feier, Flavia H / Grezzana-Filho, Tomaz J M / Chedid, Marcio F / Leipnitz, Ian / Chedid, Aljamir D / de Araujo, Alexandre / Alvares-da-Silva, Mario R / Kruel, Cleber R P

HPB : the official journal of the International Hepato Pancreato Biliary Association

2023 Volume 26, Issue 1, Page(s) 137–144

Abstract: Background: Celiac trunk compression by the median arcuate ligament (MAL) increases the risk of ischemic complications following gastrointestinal surgical procedures. Previous studies suggest increased risk of hepatic artery thrombosis (HAT) in ... ...

Abstract	Background: Celiac trunk compression by the median arcuate ligament (MAL) increases the risk of ischemic complications following gastrointestinal surgical procedures. Previous studies suggest increased risk of hepatic artery thrombosis (HAT) in orthotopic liver transplant (OLT) recipients. The aim of this study is to investigate the impact of untreated MAL compression (MAL-C) on biliary complications in OLT. Methods: Contrast-enhanced imaging was used to classify celiac trunk stenosis by MAL-C. Medical records were reviewed to extract pre-transplant, transplant and post-transplant data. Patients were divided into two groups: no MAL compression (nMAL-C) and MAL-C. The primary endpoint was biliary complications. Secondary endpoints were HAT and graft survival. Results: 305 OLT were performed from 2010 to 2021, of which 219 were included for analysis: 185 (84.5%) patients without and 34 (15.5%) with MAL-C. The incidence of HAT was 5.9% in both groups. Biliary complications were more common in the MAL-C group (35.3% vs. 17.8%, p = 0.035). Graft survival was decreased in patients with MAL-C (p = 0.035). Conclusions: MAL-C of the celiac trunk was associated with increased risk of biliary complications and inferior graft survival in OLT patients. These findings highlight the importance of preoperative screening and treatment of MAL in this population.
MeSH term(s)	Humans ; Liver Transplantation/adverse effects ; Liver Transplantation/methods ; Hepatic Artery/diagnostic imaging ; Hepatic Artery/surgery ; Constriction, Pathologic/complications ; Constriction, Pathologic/surgery ; Celiac Artery/diagnostic imaging ; Celiac Artery/surgery ; Thrombosis ; Biliary Tract ; Ligaments/diagnostic imaging ; Ligaments/surgery
Language	English
Publishing date	2023-09-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2131251-5
ISSN	1477-2574 ; 1365-182X
ISSN (online)	1477-2574
ISSN	1365-182X
DOI	10.1016/j.hpb.2023.09.007
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Article ; Online: Effect of a short-term whole-body high-intensity interval training on fitness, morphological, and functional parameters in untrained individuals.

Evangelista, Alexandre L / Brigatto, Felipe A / DE Camargo, Júlio B / Braz, Tiago V / Bocalini, Danilo S / Teixeira, Cauê V / Paunksnis, Marcos R / Barros, Bruna M / Santos, Letícia M / Carnevali Junior, Luiz C

The Journal of sports medicine and physical fitness

2021 Volume 62, Issue 9, Page(s) 1153–1161

Abstract: Background: High-intensity interval training protocols using the body weight (WB-HIIT) as resistance could be an interesting and inexpensive alternative due to the absence of equipment required (low cost) and the possibility to be performed in a wide ... ...

Abstract	Background: High-intensity interval training protocols using the body weight (WB-HIIT) as resistance could be an interesting and inexpensive alternative due to the absence of equipment required (low cost) and the possibility to be performed in a wide range of locations. Therefore, the purpose of the present study was to analyze the effects of a short-term WB-HIIT protocol on muscle thickness (MT), muscular endurance (ME), one maximum repetition test (1RM), and maximum oxygen uptake (VO<inf>2max</inf>) of untrained individuals. Methods: Fifty healthy men (28.2±6.7 years, 77.5±26.2 kg, 171±10 cm, 23.2±8.2% Fat) were randomized into WB-HIIT (N.=25) or control (CON, N.=25) group. The WB-HIIT performed 9 exercises (40-second stimulus in all out intensity/ 20-second of passive recovery) divided into 3 blocks with 2 sets each for 6 weeks (three times a week). Results: Only WB-HIIT resulted in a significant increase in MT, ME, 1RM, and VO<inf>2max</inf> (all P<0.05) outcomes and were significantly greater compared to CON (all P<0.05). Conclusions: Our results demonstrate that a WB-HIIT program can be a time-efficient strategy to promote changes on fitness, morphological and functional parameters in previously untrained sedentary individuals.
MeSH term(s)	Adult ; Exercise/physiology ; Exercise Test ; High-Intensity Interval Training/methods ; Humans ; Male ; Oxygen ; Oxygen Consumption ; Young Adult
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2021-06-22
Publishing country	Italy
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	410823-1
ISSN	1827-1928 ; 0022-4707
ISSN (online)	1827-1928
ISSN	0022-4707
DOI	10.23736/S0022-4707.21.12342-4
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Article ; Online: Prevalence of behavior problems and associated factors in preschool children from the city of Salvador, state of Bahia, Brazil.

Santos, Letícia M Dos / Queirós, Fernanda C / Barreto, Maurício L / Santos, Darci N Dos

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

2015 Volume 38, Issue 1, Page(s) 46–52

Abstract: Objective: To identify the prevalence of internalizing and externalizing behavior problems among preschoolers from the city of Salvador, state of Bahia, Brazil, and their associations with maternal mental health and family characteristics.: Methods: ... ...

Abstract	Objective: To identify the prevalence of internalizing and externalizing behavior problems among preschoolers from the city of Salvador, state of Bahia, Brazil, and their associations with maternal mental health and family characteristics. Methods: This was a cross-sectional study of 349 children aged 49 to 72 months, randomly selected from 20,000 households representing the range of socioeconomic and environmental conditions in Salvador. In 1999, we assessed sociodemographic variables and family environment characteristics. In 2001, we used the Child Behavior Checklist to measure and describe the frequencies of behavior problems. We conducted bivariate and multivariate analysis to estimate associations between family and maternal factors and prevalence of behavior problems. Results: The overall prevalence of behavior problems was 23.5%. The prevalence of internalizing problems was 9.7%, and that of externalizing problems, 25.2%. Behavior problems were associated with several maternal mental health variables, namely: presence of at least one psychiatric diagnosis (odds radio [OR] 3.01, 95%CI 1.75-5.18), anxiety disorder (OR 2.06, 95%CI 1.20-3.46), affective disorder (OR 2.10, 95%CI 1.21-3.65), and mental health disorders due to use of psychoactive substances (OR 2.31, 95%CI 1.18-4.55). Conclusion: The observed prevalence of child behavior problems fell within the range reported in previous studies. Maternal mental health is an important risk factor for behavior problems in preschool-aged children.
MeSH term(s)	Brazil/epidemiology ; Child ; Child Behavior Disorders/epidemiology ; Child Behavior Disorders/psychology ; Child, Preschool ; Cross-Sectional Studies ; Family Characteristics ; Female ; Humans ; Male ; Mental Disorders/epidemiology ; Mental Disorders/psychology ; Mental Health/statistics & numerical data ; Mother-Child Relations ; Mothers/psychology ; Mothers/statistics & numerical data ; Prevalence ; Risk Factors ; Social Environment
Language	English
Publishing date	2015-09-15
Publishing country	Brazil
Document type	Journal Article
ISSN	1809-452X
ISSN (online)	1809-452X
DOI	10.1590/1516-4446-2014-1596
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Article ; Online: Impact of etonogestrel-releasing implant and copper intrauterine device on carbohydrate metabolism: a comparative study.

Oderich, Carolina L / Wender, Maria Celeste O / Lubianca, Jaqueline N / Santos, Letícia M / de Mello, Grasiele C

Contraception

2012 Volume 85, Issue 2, Page(s) 173–176

Abstract: Background: We investigated the influence of an etonogestrel-releasing (ETG) implant and copper intrauterine device (IUD) on carbohydrate metabolism.: Study design: In this nonrandomized, open-label, prospective controlled trial, 40 healthy women ... ...

Abstract	Background: We investigated the influence of an etonogestrel-releasing (ETG) implant and copper intrauterine device (IUD) on carbohydrate metabolism. Study design: In this nonrandomized, open-label, prospective controlled trial, 40 healthy women received an implant or IUD (20 per group). Outcome measures were fasting glucose, fasting insulin, oral glucose tolerance test (OGTT) and glycosylated hemoglobin A(1)C (HbA(1)C) levels at baseline and after 6 and 12 months. Results: The groups were similar in age, body mass index and laboratory parameters at baseline. Carbohydrate metabolism was not modified by the ETG implant at baseline and at 6 and 12 months (mean ± SD) (fasting glucose: 85.9 ± 5.13, 87.05 ± 5.36, 88.19 ± 5.05; insulin: 7.77 ± 2.42, 10.64 ± 9.4, 8.82 ± 3.73; OGTT: 94.8 ± 25.28, 96.5 ± 19.67, 99.47 ± 24.6; HbA(1)C: 5.27 ± .34, 5.55 ± .39, 5.7 ± 0.37). The same was true for the IUD (fasting glucose: 88.87 ± 7.2, 89.65 ± 5.86, 88.75 ± 4.79; insulin: 7.94 ± 3.6, 8.3 ± 4.1, 7.34 ± 3.02; OGTT: 96.85 ± 15.16, 97.48 ± 13.42, 91.3 ± 22.16; HbA(1)C: 5.41 ± .49, 5.75 ± .41, 5.9 ± 0.73). Conclusions: The ETG-releasing implant did not affect carbohydrate metabolism in normal women after 12 months.
MeSH term(s)	Adult ; Carbohydrate Metabolism/drug effects ; Contraceptive Agents, Female/adverse effects ; Desogestrel/adverse effects ; Female ; Humans ; Intrauterine Devices, Copper ; Prospective Studies ; Young Adult
Chemical Substances	Contraceptive Agents, Female ; etonogestrel (304GTH6RNH) ; Desogestrel (81K9V7M3A3)
Language	English
Publishing date	2012-02
Publishing country	United States
Document type	Clinical Trial ; Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80106-9
ISSN	1879-0518 ; 0010-7824
ISSN (online)	1879-0518
ISSN	0010-7824
DOI	10.1016/j.contraception.2011.05.018
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Article ; Online: Screening for common mental disorders using the SRQ-20 in Brazil: what are the alternative strategies for analysis?

Barreto do Carmo, Maria B / Santos, Leticia M Dos / Feitosa, Caroline A / Fiaccone, Rosemeire L / Silva, Nívea B da / Santos, Darci N Dos / Barreto, Maurício L / Amorim, Leila D

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

2017 Volume 40, Issue 2, Page(s) 115–122

Abstract: Objective: To analyze the prevalence of common mental disorders (CMD) assessed with the Self Reporting Questionnaire (SRQ-20), using the established cutoff point, and comparing it with the results of a joint correspondence factor analysis (CFA) and ... ...

Abstract	Objective: To analyze the prevalence of common mental disorders (CMD) assessed with the Self Reporting Questionnaire (SRQ-20), using the established cutoff point, and comparing it with the results of a joint correspondence factor analysis (CFA) and cluster analysis and of a latent class analysis (LCA). Methods: A cross-sectional study was carried out in an urban sample of 1,095 women aged 19 to 55 years. Joint CFA-cluster analysis and LCA were used. Results: We found a high prevalence of CMD, regardless of classification method (37.6% when using the cutoff point; 44.4% and 52% for LCA and joint CFA-cluster, respectively). The alternative analysis strategies describe the cases more efficiently when compared to the traditional cutoff method, especially regarding more severe symptoms. Both alternative strategies also provide a description of the SRQ-20 dimensions in their particularities, which may be useful for the planning and implementation of specific actions in a given population. Conclusion: The SRQ-20 cutoff point seems to underestimate the magnitude of CMD among women. The alternative methods of analysis presented herein highlight the different possibilities of using this important instrument of screening for mental health.
MeSH term(s)	Adult ; Aged ; Brazil/epidemiology ; Cross-Sectional Studies ; Factor Analysis, Statistical ; Female ; Humans ; Mental Disorders/diagnosis ; Mental Disorders/epidemiology ; Middle Aged ; Prevalence ; Psychiatric Status Rating Scales ; Self Report ; Socioeconomic Factors ; Surveys and Questionnaires ; Urban Population
Language	English
Publishing date	2017-08-30
Publishing country	Brazil
Document type	Journal Article
ISSN	1809-452X
ISSN (online)	1809-452X
DOI	10.1590/1516-4446-2016-2139
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Article ; Online: African biogeographical ancestry, atopic and non-atopic asthma and atopy: A study in Latin American children.

da Silva, Thiago M / Fiaccone, Rosemeire L / Kehdy, Fernanda S G / Tarazona-Santos, Eduardo / Rodrigues, Laura C / Costa, Gustavo N O / Figueiredo, Camila A / Dos Santos, Darci N / Feitosa, Caroline A / Fattore, Gisel L / Santos, Leticia M / Alcantara-Neves, Neuza M / Cruz, Álvaro A / Barreto, Maurício L

Pediatric pulmonology

2018 Volume 54, Issue 2, Page(s) 125–132

Abstract: Background: Genetic variants underlying African ancestry have been suggested be implicated in the ethnic-racial inequalities reported for asthma and allergies.: Objectives: To investigate the association between individual African ancestry and asthma ...

Abstract	Background: Genetic variants underlying African ancestry have been suggested be implicated in the ethnic-racial inequalities reported for asthma and allergies. Objectives: To investigate the association between individual African ancestry and asthma symptoms, atopic and non-atopic asthma, and atopy in children. Methods: A cross-sectional study encompassing 1190 individuals was conducted. African biogeographic ancestry was estimated using 370 539 genome-wide SNPs. Serum levels of specific IgE were measured, and skin prick test (SPT) performed for the most common local aeroallergens. Information on asthma symptoms was obtained by applying the International Study of Allergy and Asthma in Childhood questionnaire. The associations between the proportion of individual African ancestry and the outcomes investigated were analyzed through multivariate models adjusted for socio-environmental variables, infections markers, and psychosocial factors. Results: Each 20% increase in the proportion of African ancestry was negatively associated with SPT reactivity (OR: 0.79, 95%CI: 0.66-0.96) and positively associated with asthma symptoms in non-atopic individuals (OR: 1.40, 95%CI: 1.03-1.89). We estimated that socioeconomic status and number of infections mediated 28.4% of the effect of African ancestry on SPT reactivity, while 20.2% of the effect on non-atopic asthma was explained by socioeconomic status and behavioral problems in children. Conclusions: The negative association observed between African ancestry and atopy is most probably explained by unobserved environmental or social factors that covariate with ancestry. For non-atopic asthma, in turn, putative genetic variants of risk underlying African ancestry may play some role.
MeSH term(s)	African Continental Ancestry Group/genetics ; Allergens/immunology ; Asthma/blood ; Asthma/genetics ; Asthma/immunology ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Hypersensitivity, Immediate/blood ; Hypersensitivity, Immediate/genetics ; Hypersensitivity, Immediate/immunology ; Immunoglobulin E/blood ; Infant ; Infant, Newborn ; Latin America ; Male ; Polymorphism, Single Nucleotide ; Skin Tests
Chemical Substances	Allergens ; Immunoglobulin E (37341-29-0)
Language	English
Publishing date	2018-12-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632784-9
ISSN	1099-0496 ; 8755-6863
ISSN (online)	1099-0496
ISSN	8755-6863
DOI	10.1002/ppul.24213
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Article ; Online: Influence of domestic violence on the association between malnutrition and low cognitive development.

Silva, Rita de C R / Assis, Ana M O / Hasselmann, Maria H / dos Santos, Letícia M / Pinto, Elizabete de J / Rodrigues, Laura C

Jornal de pediatria

2012 Volume 88, Issue 2, Page(s) 149–154

Abstract: Objectives: To investigate the size and direction of the association between malnutrition and low cognitive performance and to evaluate the effect of domestic violence on this association.: Methods: This cross-sectional study enrolled students of ... ...

Abstract	Objectives: To investigate the size and direction of the association between malnutrition and low cognitive performance and to evaluate the effect of domestic violence on this association. Methods: This cross-sectional study enrolled students of both sexes, aged 7 to 14 years old, attending public elementary schools. The Raven's Progressive Matrices Test was used to measure cognitive development, the Revised Conflict Tactics Scales (CTS2), to measure domestic violence, and the body mass index (BMI) for age and sex, to define anthropometric indices. Socioeconomic data and information about food intake were also collected. Malnutrition was defined as BMI < 3rd percentile. Cognitive deficit was defined when the results of Raven's test were ≤ 25th percentile. Family violence was defined as a positive answer in at least one item about severe physical violence in the last 12 months. The size of the associations of interest was expressed as prevalence ratio (PR) and 95% confidence interval (95%CI). Results: Below-average intellectual development was found for 63.3% of the participants. Malnutrition was identified in 9.5%. Malnutrition had a negative effect on cognitive performance (adjusted prevalence ratio [aPR] = 1.60, 95% CI = 1.01 - 2.52; p = 0.042) when adjusted for the association between exposure to domestic violence and age. Conclusion: The association between malnutrition and below-average intellectual development found in this study was affected by domestic violence, which must be taken into account when addressing the problem.
MeSH term(s)	Adolescent ; Body Mass Index ; Child ; Cognition Disorders/complications ; Cognition Disorders/epidemiology ; Domestic Violence/statistics & numerical data ; Epidemiologic Methods ; Female ; Humans ; Intelligence Tests ; Male ; Malnutrition/complications ; Malnutrition/epidemiology ; Malnutrition/pathology ; Reference Values
Language	English
Publishing date	2012-04-11
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	731324-x
ISSN	1678-4782 ; 0021-7557
ISSN (online)	1678-4782
ISSN	0021-7557
DOI	10.2223/JPED.2176
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Article ; Online: Behavior problems and prevalence of asthma symptoms among Brazilian children.

Feitosa, Caroline A / Santos, Darci N / Barreto do Carmo, Maria B / Santos, Letícia M / Teles, Carlos A S / Rodrigues, Laura C / Barreto, Mauricio L

Journal of psychosomatic research

2011 Volume 71, Issue 3, Page(s) 160–165

Abstract: Objective: Asthma is the most common chronic disease in childhood and has been designated a public health problem due to the increase in its prevalence in recent decades, the amount of health service expenditure it absorbs and an absence of consensus ... ...

Abstract	Objective: Asthma is the most common chronic disease in childhood and has been designated a public health problem due to the increase in its prevalence in recent decades, the amount of health service expenditure it absorbs and an absence of consensus about its etiology. The relationships among psychosocial factors and the occurrence, symptomatology, and severity of asthma have recently been considered. There is still controversy about the association between asthma and a child's mental health, since the pathways through which this relationship is established are complex and not well researched. This study aims to investigate whether behavior problems are associated with the prevalence of asthma symptoms in a large urban center in Latin America. Methods: It is a cross-section study of 869 children between 6 and 12 years old, residents of Salvador, Brazil. The International Study of Allergy and Asthma in Childhood (ISAAC) instrument was used to evaluate prevalence of asthma symptoms. The Child Behavior Checklist (CBCL) was employed to evaluate behavioral problems. Results: 19.26% (n=212) of the children presented symptoms of asthma. 35% were classified as having clinical behavioral problems. Poisson's robust regression model demonstrated a statistically significant association between the presence of behavioral problems and asthma symptoms occurrence (PR: 1.43; 95% CI: 1.10-1.85). Conclusion: These results suggest an association between behavioral problems and pediatric asthma, and support the inclusion of mental health care in the provision of services for asthma morbidity.
MeSH term(s)	Asthma/psychology ; Brazil/epidemiology ; Child ; Child Behavior Disorders/epidemiology ; Child Behavior Disorders/psychology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Mental Health ; Prevalence
Language	English
Publishing date	2011-03-21
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80166-5
ISSN	1879-1360 ; 0022-3999
ISSN (online)	1879-1360
ISSN	0022-3999
DOI	10.1016/j.jpsychores.2011.02.004
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Article ; Online: Determinants of cognitive function in childhood

Almeida-Filho Naomar M / Prado Matildes S / Strina Agostino / Santos Carlos / Santos Letícia M / Bastos Ana / Assis Ana / Santos Darci N / Rodrigues Laura C / Barreto Mauricio L

BMC Public Health, Vol 8, Iss 1, p

A cohort study in a middle income context

2008 Volume 202

Abstract: Abstract Background There is evidence that poverty, health and nutrition affect children's cognitive development. This study aimed to examine the relative contributions of both proximal and distal risk factors on child cognitive development, by breaking ... ...

Abstract	Abstract Background There is evidence that poverty, health and nutrition affect children's cognitive development. This study aimed to examine the relative contributions of both proximal and distal risk factors on child cognitive development, by breaking down the possible causal pathways through which poverty affects cognition. Methods This cohort study collected data on family socioeconomic status, household and neighbourhood environmental conditions, child health and nutritional status, psychosocial stimulation and nursery school attendance. The effect of these on Wechsler Pre-School and Primary Scale of Intelligence scores at five years of age was investigated using a multivariable hierarchical analysis, guided by the proposed conceptual framework. Results Unfavourable socioeconomic conditions, poorly educated mother, absent father, poor sanitary conditions at home and in the neighbourhood and low birth weight were negatively associated with cognitive performance at five years of age, while strong positive associations were found with high levels of domestic stimulation and nursery school attendance. Conclusion Children's cognitive development in urban contexts in developing countries could be substantially increased by interventions promoting early psychosocial stimulation and preschool experience, together with efforts to prevent low birth weight and promote adequate nutritional status.
Keywords	Public aspects of medicine ; RA1-1270
Subject code	360
Language	English
Publishing date	2008-06-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
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