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  1. AU="Santos, Maria Leonor"
  2. AU=Saluja Bharat
  3. AU="Nezhadi, Akram"
  4. AU=Dhar Debojyoti
  5. AU="Chandrappa S"
  6. AU="Cole, Kevin"
  7. AU=De Ceukelaire Wim
  8. AU=Tomatis L
  9. AU=Chandra Sharad
  10. AU="Mishra, Malvika"
  11. AU="Bruggemann, Kira"
  12. AU="Miura, Tanya A."
  13. AU="Kobeasy, Mohamed I."
  14. AU="Sonthonnax, Florian" AU="Sonthonnax, Florian"
  15. AU="Wang, Rongzu"

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  1. Artikel: Virulence factors in carbapenem-resistant hypervirulent

    Mendes, Gabriel / Santos, Maria Leonor / Ramalho, João F / Duarte, Aida / Caneiras, Cátia

    Frontiers in microbiology

    2023  Band 14, Seite(n) 1325077

    Abstract: Hypervirulence and carbapenem-resistant have emerged as two distinct evolutionary pathotypes ... ...

    Abstract Hypervirulence and carbapenem-resistant have emerged as two distinct evolutionary pathotypes of
    Sprache Englisch
    Erscheinungsdatum 2023-11-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1325077
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Cost-effectiveness of mandatory folic acid fortification of flours in prevention of neural tube defects: A systematic review.

    Rodrigues, Viviane Belini / Silva, Everton Nunes da / Santos, Maria Leonor Pacheco

    PloS one

    2021  Band 16, Heft 10, Seite(n) e0258488

    Abstract: Background: Neural tube defects (NTDs) constitute the most frequent group among congenital malformations and are the main cause of neonatal morbimortality. Folic acid (FA) can reduce the risk of pregnancies affected by NTDs.: Objective: We aimed to ... ...

    Abstract Background: Neural tube defects (NTDs) constitute the most frequent group among congenital malformations and are the main cause of neonatal morbimortality. Folic acid (FA) can reduce the risk of pregnancies affected by NTDs.
    Objective: We aimed to investigate whether mandatory folic acid (FA) fortification of flours is cost-effective as compared to non-mandatory fortification, and to verify whether FA dosage, cost composition, and the quality of economic studies influence the cost-effectiveness of outcomes.
    Methods: We conducted a systematic review. The protocol was registered on PROSPERO (CRD 42018115682). A search was conducted using the electronic databases MEDLINE/PubMed, Web of Science, Embase, Scopus, and EBSCO/CINAHL between January 2019 and October 2020 and updated in February 2021. Eligible studies comprised original economic analyses of mandatory FA fortification of wheat and corn flours (maize flours) compared to strategies of non-mandatory fortification in flours and/or use of FA supplements for NTD prevention. The Drummond verification list was used for quality analysis.
    Results: A total of 7,859 studies were identified, of which 13 were selected. Most (77%; n = 10) studies originated from high-income countries, while three (23%) were from upper-middle-income countries. Results of a cost-effectiveness analysis showed that fortification is cost-effective for NTD prevention, except for in one study in New Zealand. The cost-benefit analysis yielded a median ratio of 17.5:1 (0.98:1 to 417.1:1), meaning that for each monetary unit spent in the program, there would be a return of 17.5 monetary units. Even in the most unfavorable case of mandatory fortification, the investment in the program would virtually payoff at a ratio of 1:0.98. All FA dosages were cost-effective and offered positive health gains, except in one study. The outcomes of two studies showed that FA dosages above 300 μg/100 g have a higher CBA ratio. The studies with the inclusion of "loss of consumer choice" in the analysis may alter the fortification cost-efficacy ratio.
    Conclusion: We expect the findings to be useful for public agencies in different countries in decision-making on the implementation and/or continuity of FA fortification as a public policy in NTD prevention.
    Mesh-Begriff(e) Humans ; Neural Tube Defects
    Sprache Englisch
    Erscheinungsdatum 2021-10-21
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Systematic Review
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0258488
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: A Transcriptomic Approach to the Metabolism of Tetrapyrrolic Photosensitizers in a Marine Annelid.

    Santos, Maria Leonor / D'Ambrosio, Mariaelena / Rodrigo, Ana P / Parola, A Jorge / Costa, Pedro M

    Molecules (Basel, Switzerland)

    2021  Band 26, Heft 13

    Abstract: The past decade has seen growing interest in marine natural pigments for biotechnological applications. One of the most abundant classes of biological pigments is the tetrapyrroles, which are prized targets due their photodynamic properties; porphyrins ... ...

    Abstract The past decade has seen growing interest in marine natural pigments for biotechnological applications. One of the most abundant classes of biological pigments is the tetrapyrroles, which are prized targets due their photodynamic properties; porphyrins are the best known examples of this group. Many animal porphyrinoids and other tetrapyrroles are produced through heme metabolic pathways, the best known of which are the bile pigments biliverdin and bilirubin.
    Mesh-Begriff(e) Animals ; Chromatography, High Pressure Liquid ; Epidermis/metabolism ; Gene Expression Profiling/methods ; Gene Regulatory Networks ; Metabolic Networks and Pathways ; Metabolomics/methods ; Organ Specificity ; Photosensitizing Agents/metabolism ; Polychaeta/genetics ; Polychaeta/metabolism ; Sequence Analysis, RNA ; Species Specificity ; Tetrapyrroles/genetics ; Tetrapyrroles/metabolism
    Chemische Substanzen Photosensitizing Agents ; Tetrapyrroles
    Sprache Englisch
    Erscheinungsdatum 2021-06-27
    Erscheinungsland Switzerland
    Dokumenttyp Comparative Study ; Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26133924
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.MO 81: Hefte anzeigen

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  4. Artikel ; Online: Microbial Source Tracking as a Method of Determination of Beach Sand Contamination.

    Valério, Elisabete / Santos, Maria Leonor / Teixeira, Pedro / Matias, Ricardo / Mendonça, João / Ahmed, Warish / Brandão, João

    International journal of environmental research and public health

    2022  Band 19, Heft 13

    Abstract: Beach sand may act as a reservoir for numerous microorganisms, including enteric pathogens. Several of these pathogens originate in human or animal feces, which may pose a public health risk. In August 2019, high levels of fecal indicator bacteria (FIB) ... ...

    Abstract Beach sand may act as a reservoir for numerous microorganisms, including enteric pathogens. Several of these pathogens originate in human or animal feces, which may pose a public health risk. In August 2019, high levels of fecal indicator bacteria (FIB) were detected in the sand of the Azorean beach Prainha, Terceira Island, Portugal. Remediation measures were promptly implemented, including sand removal and the spraying of chlorine to restore the sand quality. To determine the source of the fecal contamination, during the first campaign, supratidal sand samples were collected from several sites along the beach, followed by microbial source tracking (MST) analyses of
    Mesh-Begriff(e) Animals ; Bacteria/classification ; Bacteria/genetics ; Bacteria/isolation & purification ; Bacteroides/genetics ; Bacteroides/isolation & purification ; Bathing Beaches/standards ; Charadriiformes ; Dogs ; Environmental Monitoring/methods ; Feces/microbiology ; Portugal ; Ruminants ; Sand/microbiology ; Water Microbiology ; Water Pollution/analysis
    Chemische Substanzen Sand
    Sprache Englisch
    Erscheinungsdatum 2022-06-28
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19137934
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Genomic characterisation of a novel KPC-98-producing clinical Klebsiella pneumoniae strain conferring resistance to ceftazidime/avibactam.

    Mendes, Gabriel / Santos, Maria Leonor / Ramalho, João F / Bruschy-Fonseca, Ana / Lito, Luís / Mendes-Pedro, Diogo / Duarte, Aida / Melo-Cristino, José / Caneiras, Cátia

    International journal of antimicrobial agents

    2023  Band 62, Heft 6, Seite(n) 107013

    Mesh-Begriff(e) Humans ; Ceftazidime/pharmacology ; Klebsiella pneumoniae/genetics ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Azabicyclo Compounds/pharmacology ; Drug Combinations ; Genomics ; Klebsiella Infections/drug therapy ; beta-Lactamases/genetics ; Microbial Sensitivity Tests ; Bacterial Proteins/genetics
    Chemische Substanzen Ceftazidime (9M416Z9QNR) ; avibactam (7352665165) ; Anti-Bacterial Agents ; Azabicyclo Compounds ; Drug Combinations ; beta-Lactamases (EC 3.5.2.6) ; Bacterial Proteins
    Sprache Englisch
    Erscheinungsdatum 2023-10-22
    Erscheinungsland Netherlands
    Dokumenttyp Letter
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2023.107013
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 3368: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 500: Hefte anzeigen

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  6. Buch: O Domínio de Santa Maria do Lorvão no século XIV

    Santos, Maria Leonor Ferraz de Oliveira Silva

    gestão feminina de um património fundiário

    (Temas portugueses)

    2002  

    Verfasserangabe Maria Leonor Ferraz de Oliveira Silva Santos
    Serientitel Temas portugueses
    Sprache Portugiesisch
    Umfang 195 S, graph., Darst., Kt
    Verlag Imprensa Nacional-Casa da Moeda
    Erscheinungsort Lisboa
    Dokumenttyp Buch
    ISBN 9722711032 ; 9789722711036
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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