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  1. Article ; Online: Neurofibromatosis type 1 and pulmonary arterial hypertension: A case report.

    Santos, Marina Raquel / Pereira, Andreia Micaela

    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

    2022  Volume 41, Issue 6, Page(s) 511.e1–511.e5

    Abstract: Neurofibromatosis type 1 (NF1) is a common autosomal dominant genetic disorder that affects multiple organ systems and has a wide range of clinical manifestations. Pulmonary hypertension (PH) associated with NF1 (PH-NF1) is rarely seen, but confers a ... ...

    Abstract Neurofibromatosis type 1 (NF1) is a common autosomal dominant genetic disorder that affects multiple organ systems and has a wide range of clinical manifestations. Pulmonary hypertension (PH) associated with NF1 (PH-NF1) is rarely seen, but confers a dismal prognosis. In the literature this association has been described in only 31 cases. The authors report the case of a 77-year-old female patient with NF1 complicated by severe precapillary PH despite triple disease-specific oral combination therapy. Because no data are available on the efficacy of specific PH therapy in PH-NF1, these patients should be assessed in expert PH centers and referred for lung transplantation at an early stage.
    Language Portuguese
    Publishing date 2022-05-20
    Publishing country Portugal
    Document type Case Reports
    ZDB-ID 632718-7
    ISSN 2174-2030 ; 0870-2551 ; 0304-4750
    ISSN (online) 2174-2030
    ISSN 0870-2551 ; 0304-4750
    DOI 10.1016/j.repc.2019.05.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: COVID-19-Associated Cognitive Biases on Pneumonia Differential Diagnosis.

    Cruz, Pedro / Meireles, Ana M / Santos, Marina / Rodrigues, Maria R

    Cureus

    2024  Volume 16, Issue 2, Page(s) e55144

    Abstract: The coronavirus disease 2019 (COVID-19) pandemic favors cognitive biases such as anchoring and availability biases. The first refers to overvaluing some of the initial information and establishing a diagnosis too early, with resistance to future ... ...

    Abstract The coronavirus disease 2019 (COVID-19) pandemic favors cognitive biases such as anchoring and availability biases. The first refers to overvaluing some of the initial information and establishing a diagnosis too early, with resistance to future adjustments. The latter happens when diagnoses more frequently considered are regarded as more common in reality. This case, in which the correct diagnosis was delayed due to these biases, highlights the need to remain aware of them as a means toward timely diagnosis and therapeutic success of pneumonia cases. An 84-year-old woman presented with a mild non-productive cough for two months and fever. She had a history of breast carcinoma treated with radiotherapy in the previous year. Computerized tomography (CT) showed extensive bilateral consolidation foci with ground-glass-opacification areas and bilateral pleural effusion, CO-RADS 3. COVID-19 with bacterial superinfection was suspected and levofloxacin was initiated. Nasopharyngeal swab polymerase chain reaction (PCR) was carried out three times, always negative for SARS-CoV-2. As the patient remained with fever and cough, the antibiotic was escalated to piperacillin/tazobactam and then to meropenem/vancomycin. She underwent bronchofibroscopy and alveolar lavage, with negative SARS-CoV-2 PCR. The re-evaluation CT scan maintained bilateral consolidations, with an aerial bronchogram. The biopsy of pulmonary consolidation allowed the diagnosis of radiation-induced organizing pneumonia. Prednisolone was initiated and achieved clinical remission and radiological improvement. This case highlights the need to remain aware of cognitive biases both when COVID-19 is suspected or ruled out and to consider other diagnoses when there is a lack of therapeutic response.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Tricky Diagnosis: An Aberrant Mitral Valve Chord.

    Santos, Marina / Paiva, Mariana / Ferreira, Joana / Guerreiro, Sara

    Arquivos brasileiros de cardiologia

    2023  Volume 120, Issue 3, Page(s) e20220573

    Title translation Diagnóstico Complicado: Uma Corda Aberrante da Valva Mitral.
    MeSH term(s) Humans ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/surgery ; Heart Valve Prosthesis Implantation
    Language Portuguese
    Publishing date 2023-03-10
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20220573
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Haff's disease in Brazil - the need for scientific follow-up and case notification.

    da Silva Júnior, Flavio Manoel Rodrigues / Dos Santos, Marina

    Lancet regional health. Americas

    2021  Volume 5, Page(s) 100100

    Language English
    Publishing date 2021-11-18
    Publishing country England
    Document type Journal Article
    ISSN 2667-193X
    ISSN (online) 2667-193X
    DOI 10.1016/j.lana.2021.100100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sexual dimorphism and allometry in malacophagus snakes (Dipsadidae: Dipsadinae).

    Dos Santos, Marina Meireles / Klaczko, Julia / da Costa Prudente, Ana Lúcia

    Zoology (Jena, Germany)

    2022  Volume 153, Page(s) 126026

    Abstract: Sexual dimorphism in snakes is generally described in association with body or tail size and scale counts, with relatively few studies addressing intrasexual divergence in the skull. Here, we analyzed sexual dimorphism in the size and shape of skull and ... ...

    Abstract Sexual dimorphism in snakes is generally described in association with body or tail size and scale counts, with relatively few studies addressing intrasexual divergence in the skull. Here, we analyzed sexual dimorphism in the size and shape of skull and body in three malacophagous dipsadine snakes, Dipsas mikanii, Dipsas neuwiedi and Dipsas turgida, as well as allometric effect on these components. We used linear and geometric analysis to assess: (1) if there is sexual dimorphism in cranial components; (2) if there are differences between the sexes regarding body and tail size, number of ventral and subcaudal scales; (3) whether there is covariation between cranial components and body size; (4) if there are changes in cranial shape associated with increased size; and (5) whether there is an allometric relationship between body and tail size. Our results showed that all three species are dimorphic in cranial shape and size (except D. turgida for cranial size), with females having longer and thinner skulls than males. In the three species, the female skull was negatively allometric, whereas the male skull was isometric. Allometry related to cranial shape was significant only in males of D. turgida, which showed greater snout robustness and eye size associated with enlargement of the skull. Females of D. mikanii and D. neuwiedi were significantly larger than males. Only males of D. neuwiedi showed positive allometry for the tail, while dimorphism related to scale counts followed the pattern found in most snakes, with females having a greater number of ventrals and males subcaudals (except D. neuwiedi in the latter case). Based on our results, we hypothesize that patterns of sexual dimorphism and skull allometry in malacophagous snakes may be explained both by aspects related to diet and reproduction. Meanwhile, patterns associated with body size reflect advantages related to fecundity favoring greater reproductive success of females.
    MeSH term(s) Animals ; Body Size ; Female ; Head ; Male ; Sex Characteristics ; Skull/anatomy & histology ; Snakes
    Language English
    Publishing date 2022-06-22
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1191401-4
    ISSN 1873-2720 ; 0944-2006
    ISSN (online) 1873-2720
    ISSN 0944-2006
    DOI 10.1016/j.zool.2022.126026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: What happens when Schwann cells are exposed to

    Brügger, Lara Machado de Oliveira / Dos Santos, Marina Monnerat Lemos / Lara, Flavio Alves / Mietto, Bruno Siqueira

    IBRO neuroscience reports

    2023  Volume 15, Page(s) 11–16

    Abstract: Mycobacterium ... ...

    Abstract Mycobacterium leprae
    Language English
    Publishing date 2023-05-27
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2667-2421
    ISSN (online) 2667-2421
    DOI 10.1016/j.ibneur.2023.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Impact of pretransplantation malnutrition risk on the clinical outcome and graft survival of kidney transplant patients.

    Santos, Marina Ribeiro de Oliveira / Lasmar, Marcus Faria / Nascimento, Evaldo / Fabreti-Oliveira, Raquel Aparecida

    Jornal brasileiro de nefrologia

    2023  Volume 45, Issue 4, Page(s) 470–479

    Abstract: Background: The prevalence of malnourished patients before transplantation and the influence of malnutrition on graft and patient outcomes remain underestimated, despite being associated with higher postoperative morbidity and mortality. This study ... ...

    Abstract Background: The prevalence of malnourished patients before transplantation and the influence of malnutrition on graft and patient outcomes remain underestimated, despite being associated with higher postoperative morbidity and mortality. This study aimed to develop an easy nutritional screening tool and evaluate the impact of nutritional status on clinical outcome, graft survival (GS) and mortality risk in kidney transplant patients (KTP).
    Methods: In this retrospective cohort study including 451 KTP, we developed a score by using anthropometric, clinical, and laboratory measures performed in the pretransplant evaluation. The patients were stratified into 3 groups according to the final score: G1 (0 or 1 point)=low risk, G2 (2 to 4 points)=moderate risk, and G3 (>5 points)=high risk of malnutrition. The patients were monitored after transplantation at least 1 to 10 years.
    Results: Stratifying the 451 patients based on the pretransplant risk score, G1, G2, and G3 were composed of 90, 292, and 69 patients, respectively. Patients from G1 maintained the lowest serum creatinine levels at hospital discharge when compared with others (p = 0.012). The incidence of infection in the patients from G3 was higher than patients from G1 and G2 (p = 0.030). G3 recipients showed worse GS than G1 patients (p = 0.044). G3 patients showed almost threefold higher risk for graft loss (HR 2.94, 95% CI 1.084-7.996).
    Conclusions: KTP with higher malnutrition risk score were associated with worse outcomes and GS. The nutritional screening tool is easy to be used in clinical practice to evaluate the patient in preparation for kidney transplant.
    MeSH term(s) Humans ; Kidney Transplantation/adverse effects ; Retrospective Studies ; Nutritional Status ; Graft Survival ; Nutrition Assessment ; Malnutrition/complications ; Malnutrition/epidemiology ; Risk Factors
    Language Portuguese
    Publishing date 2023-07-12
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2057873-8
    ISSN 2175-8239 ; 2175-8239
    ISSN (online) 2175-8239
    ISSN 2175-8239
    DOI 10.1590/2175-8239-JBN-2022-0150en
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Toxicological effects of active and inert ingredients of imazethapyr formulation Verosil® against Scenedesmus vacuolatus (Chlorophyta).

    Fassiano, Anabella Victoria / March, Hugo / Santos, Marina / Juárez, Ángela Beatriz / Ríos de Molina, María Del Carmen

    Environmental science and pollution research international

    2022  Volume 29, Issue 21, Page(s) 31384–31399

    Abstract: Imazethapyr, a selective systemic herbicide, is widely used in agriculture and it is frequently detected in water bodies close to application areas. Like other agrochemicals, imazethapyr is commercialized in formulations containing a mixture of additives ...

    Abstract Imazethapyr, a selective systemic herbicide, is widely used in agriculture and it is frequently detected in water bodies close to application areas. Like other agrochemicals, imazethapyr is commercialized in formulations containing a mixture of additives that increase the effectiveness of the active ingredient. These complex mixtures may cause adverse effects on non-target primary producers, such as microalgae, when they reach freshwater bodies. The aim of this study was to assess the effects, separately, of the formulation Verosil
    MeSH term(s) Fresh Water ; Herbicides/toxicity ; Microalgae ; Nicotinic Acids/pharmacology ; Scenedesmus ; Water Pollutants, Chemical/pharmacology
    Chemical Substances Herbicides ; Nicotinic Acids ; Water Pollutants, Chemical ; imazethapyr (72T2IN94I4)
    Language English
    Publishing date 2022-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-17962-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Severe mitral regurgitation in a patient with left-ventricular endomyocardial fibrosis: a challenging case.

    Santos, Marina / Mota, Teresa / Guerreiro, Sara / Bento, Dina / Uva, Miguel Sousa

    European heart journal. Case reports

    2022  Volume 6, Issue 10, Page(s) ytac391

    Language English
    Publishing date 2022-09-22
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytac391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effects of kidney perfusion on renal stiffness and tissue fluidity measured with tomoelastography in an MRI-compatible

    Castelein, Johannes / Pamplona, Carolina / Armstrong Junior, Roberto / Vidal Dos Santos, Marina / Sack, Ingolf / Dierckx, Rudi / Moers, Cyril / Borra, Ronald

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1236949

    Abstract: Stiffness plays a vital role in diagnosing renal fibrosis. However, perfusion influences renal stiffness in various chronic kidney diseases. Therefore, we aimed to characterize the effect of tissue perfusion on renal stiffness and tissue fluidity ... ...

    Abstract Stiffness plays a vital role in diagnosing renal fibrosis. However, perfusion influences renal stiffness in various chronic kidney diseases. Therefore, we aimed to characterize the effect of tissue perfusion on renal stiffness and tissue fluidity measured by tomoelastography based on multifrequency magnetic resonance elastography in an
    Language English
    Publishing date 2023-11-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1236949
    Database MEDical Literature Analysis and Retrieval System OnLINE

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