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  1. Article ; Online: Expenses related with a well organized information about risk factors for stroke reduce mortality and burden, with diminished total health expenses.

    Sterpetti, Antonio V / Sapienza, Paolo / Borrelli, Valeria

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2023  Volume 32, Issue 12, Page(s) 107397

    MeSH term(s) Humans ; Stroke/diagnosis ; Stroke/therapy ; Cost of Illness ; Risk Factors ; Health Expenditures
    Language English
    Publishing date 2023-09-30
    Publishing country United States
    Document type Letter
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2023.107397
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    Zs.A 3519: Show issues Location:
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  2. Article ; Online: An invited commentary on 'Survival outcomes of neoadjuvant therapy followed by radical resection versus upfront surgery for stage I-III pancreatic ductal adenocarcinoma: a retrospective cohort study'.

    Coppola, Alessandro / Iannone, Immacolata / Sapienza, Paolo

    International journal of surgery (London, England)

    2023  Volume 109, Issue 11, Page(s) 3692–3693

    MeSH term(s) Humans ; Neoadjuvant Therapy ; Retrospective Studies ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/surgery ; Carcinoma, Pancreatic Ductal/drug therapy ; Carcinoma, Pancreatic Ductal/surgery ; Pancreatectomy ; Survival Rate ; Pancreatic Neoplasms
    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000000607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6502: Show issues Location:
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  3. Article: Treatment of lower limb arterial disease by Dardik graft: It takes one to know one.

    Borghese, O / Pisani, A / Sapienza, P

    Journal de medecine vasculaire

    2020  Volume 45, Issue 4, Page(s) 214–220

    Abstract: Objective: To perform a comprehensive literature review on outcomes achieved with the historical Dardik graft, illustrated with a case report of a patient with 13-years primary patency and limb salvage.: Methods: A comprehensive literature review was ...

    Abstract Objective: To perform a comprehensive literature review on outcomes achieved with the historical Dardik graft, illustrated with a case report of a patient with 13-years primary patency and limb salvage.
    Methods: A comprehensive literature review was performed through MedLine (PubMed.gov, U.S. National Library of Medicine, National Institute of Health) from 1976 to 2018 using search terms (Umbilical Vein Graft), (Dardik graft), (Glutaraldehyde stabilized human umbilical vein [HUV]) and (HUV) to collected data on clinical use of HUV. Only papers in English and reporting adequate information about indication for surgery, short- and long-term patency and complication rate were included.
    Results: Data about a total of 899 patients (977 limbs) were available. Overall, 45% of patients (438 limbs) underwent HUV implantation for critical limb ischemia (rest pain or tissue loss) or for disabling claudication in 12.2% of cases (120 limbs). Others indication for surgery were acute onset limb ischemia, popliteal aneurysms or aneurysmal degeneration of a previously implanted synthetic graft. At a mean follow-up of 4.3 years (range 3-6 years), primary patency and secondary patency were 61.3% and 61%, respectively. Aneurisms formation was detected in 3% of cases (21 limbs), graft's infection in 24.4% of cases (31 limbs) and graft's thrombosis in 25.5% of cases (193 limbs).
    Conclusion: This article provide a historical review of the use, outcomes and complications of HUV. Even though it is no longer commercially available, the knowledge of this type of substitute still remains inspirational for the development of innovative vascular conduits and fundamental for the new generations of physician both in diagnostics and in the management of complications.
    MeSH term(s) Bioprosthesis ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation/instrumentation ; Graft Occlusion, Vascular/diagnostic imaging ; Graft Occlusion, Vascular/etiology ; Graft Occlusion, Vascular/physiopathology ; Humans ; Limb Salvage ; Male ; Middle Aged ; Peripheral Arterial Disease/diagnostic imaging ; Peripheral Arterial Disease/physiopathology ; Peripheral Arterial Disease/surgery ; Prosthesis Design ; Risk Factors ; Time Factors ; Treatment Outcome ; Umbilical Veins/transplantation ; Vascular Patency
    Language English
    Publishing date 2020-05-05
    Publishing country France
    Document type Case Reports ; Journal Article ; Review
    ISSN 2542-4513
    ISSN 2542-4513
    DOI 10.1016/j.jdmv.2020.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Letter to the Editor on Endovascular Revascularization with Stent Implantation in Patients with Acute Mesenteric Ischemia due to Acute Arterial Thrombosis: Clinical Outcome and Predictive Factors.

    Lauro, Augusto / Sapienza, Paolo

    Cardiovascular and interventional radiology

    2021  Volume 44, Issue 12, Page(s) 2011–2012

    MeSH term(s) Acute Disease ; Endovascular Procedures ; Humans ; Mesenteric Ischemia/diagnostic imaging ; Mesenteric Ischemia/surgery ; Mesenteric Vascular Occlusion/diagnostic imaging ; Mesenteric Vascular Occlusion/surgery ; Retrospective Studies ; Stents ; Thrombosis/diagnostic imaging ; Treatment Outcome ; Vascular Surgical Procedures
    Language English
    Publishing date 2021-08-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-021-02942-x
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    Zs.A 1378: Show issues Location:
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  5. Article ; Online: Reduced levels of atmospheric levels of PM 2.5 and simultaneous decrease of hospital admissions for cardiovascular emergencies in Italy.

    Gabriele, Raimondo / Iannone, Iammacolata / Sapienza, Paolo / DI Marzo, Luca / Sterpetti, Antonio V

    International journal of cardiology. Cardiovascular risk and prevention

    2024  Volume 20, Page(s) 200241

    Language English
    Publishing date 2024-02-01
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2772-4875
    ISSN (online) 2772-4875
    DOI 10.1016/j.ijcrp.2024.200241
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  6. Article ; Online: Mortality and burden related with aortic aneurysms and dissections. The importance of information and education.

    Sterpetti, Antonio V / Gabriele, Raimondo / Sapienza, Paolo / Marzo, Luca Di / Borrelli, Valeria

    Current problems in cardiology

    2024  Volume 49, Issue 3, Page(s) 102384

    Abstract: Background: In this study we correlated changes of risk factors for cardiovascular diseases with trends of age standardized mortality rates and burden for aortic aneurysms and dissections.: Methods: We analyzed data from the Global Burden of Diseases ...

    Abstract Background: In this study we correlated changes of risk factors for cardiovascular diseases with trends of age standardized mortality rates and burden for aortic aneurysms and dissections.
    Methods: We analyzed data from the Global Burden of Diseases and EUROSTAT.
    Findings: There was a significant increase of expenditure for health from 1980 and 2019. In the period 1980-2000, despite higher health spending, age standardized mortality rates increased in almost all European countries. During the period 2000-2019, in Western European Countries and in Poland, Estonia, Latvia, Slovenia there was a correlation between higher health expenditure and decrease of ASMR. The most important changes between the period 1980-2000 and the period 2000-2019 was the proportion of health expenditure devoted to preventive care and to the increased use of aspirin and statins.
    Interpretation: Information about risk factors for cardiovascular diseases have leads to decreased aortic aneurysm related mortality and burden.
    MeSH term(s) Humans ; Aortic Aneurysm ; Estonia ; Aspirin ; Risk Factors ; Dissection
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2024-01-04
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2024.102384
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  7. Article ; Online: The role of education and information to prevent trends towards increase of cardiovascular mortality rates in Europe from 2015 TO 2019.

    Sterpetti, Antonio V / Gabriele, Raimondo / Iannone, Immacolata / Sapienza, Paolo / Marzo, Luca Di

    Current problems in cardiology

    2024  Volume 49, Issue 3, Page(s) 102415

    Abstract: Background: In Europe Cardio Vascular Disease (CVD) mortality rates decreased significantly in the last 25 years, with less decline in the last 5 years. The aim of our study was to analyze trends of risk factors which may explain plateauing of CVD ... ...

    Abstract Background: In Europe Cardio Vascular Disease (CVD) mortality rates decreased significantly in the last 25 years, with less decline in the last 5 years. The aim of our study was to analyze trends of risk factors which may explain plateauing of CVD mortality rates in the period 2015-2019 in Europe.
    Methods: We analyzed data from the Global Burden Disease and EUROSTAT concerning trends of CVD mortality rates for 25 European countries and simultaneous changes of exposure to risk factors of the population RESULTS: CVD related mortality decreased significantly in the analyzed countries in the period 2000-2015; in the period 2015-2019 there was a trend towards plateauing of CVD related mortality rates, which was associated with an increased exposure to several established risk factors including cigarette smoking, obesity and arterial hypertension. A decrease in expenditure for information, education and counseling programs was documented in most countries in the same period. Level of exposure to risk factors was correlated with educational attainment . Exposure to risk factors in the interval 2014-2019 increased for people with lower education, whereas decreased in people with higher education (p<0.001).
    Conclusions: Organized information about risk factors for CVD have the potential to reduce mortality and burden, with diminished total health expenses. Education and information in this setting should consider the cultural and social level of the public.
    MeSH term(s) Humans ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Educational Status ; Europe/epidemiology ; Risk Factors ; Hypertension
    Language English
    Publishing date 2024-01-20
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2024.102415
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  8. Article ; Online: Reduced carotid revascularization and screening for asymptomatc patients during the COVID-19 pandemic in Italy.

    Sterpetti, Antonio V / Di Marzo, Luca / Sapienza, Paolo / Gabriele, Raimondo / Borrelli, Valeria

    Journal of vascular surgery

    2024  Volume 79, Issue 4, Page(s) 988–990

    MeSH term(s) Humans ; COVID-19 ; Pandemics/prevention & control ; Carotid Stenosis ; Vascular Surgical Procedures ; Italy/epidemiology
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Letter
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2023.12.007
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    Zs.A 1933: Show issues Location:
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  9. Article ; Online: Clinical outcomes for patients with cardiovascular diseases before, during, and after the COVID19 pandemic. A pooled analysis of 600.000 patients.

    Sterpetti, Antonio V / Gabriele, Raimondo / Borrelli, Valeria / Campagnol, Monica / Iannone, Immacolata / Costi, Umberto / Sapienza, Paolo / Dimarzo, Luca

    Current problems in cardiology

    2024  Volume 49, Issue 6, Page(s) 102540

    Abstract: Background: The unexpected virulence of the COVID19 pandemic brought to significant changes of generally accepted therapeutic approaches. The consequences of these changes were difficult to define during the pandemic period.: Methods: We analyzed the ...

    Abstract Background: The unexpected virulence of the COVID19 pandemic brought to significant changes of generally accepted therapeutic approaches. The consequences of these changes were difficult to define during the pandemic period.
    Methods: We analyzed the National Registries including 97% of hospital admissions in Italy, regarding data describing number of operations for aortic valve implantation or repair, carotid and coronary revascularization, AAA repair, and lower limb arterial reconstruction performed in the period 2015 to 2019 and in the pandemic years 2020, 2021, and 2022. Primary outcomes were number and type of surgical procedures, 30-days operative mortality.
    Results: During the three years of the pandemic there was a statistically significant increase of the number of all-causes deaths in comparison with the mean of the previous five years (2015-2019). In Italy there was a total increase of all causes-deaths of 251.911 (+105900 in 2020; +66929 in 2021; and +79082 in 2022), and 73% of the excess of deaths was related with COVID19 infection and 27% occurred in COVID 19 negative patients. During the first year of the pandemic, worse clinical outcomes for hospitalized patients with CVD were registered. The medical system responded adequately and in the following two pandemic years clinical outcomes for hospitalized patients were similar with those of the pre-pandemic period.
    Conclusions: The unexpected virulence of COVID19 pandemic determined worse clinical outcomes for patients with CVD during the first year. The adopted preventive measures allowed in the following two pandemic years improved clinical outcomes, similar with those of the pre-pandemic period.
    Language English
    Publishing date 2024-03-21
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2024.102540
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  10. Article ; Online: Adenocarcinoma in the transposed colon: High grade active inflammation versus low grade chronic inflammation.

    Sterpetti, Antonio V / Sapienza, Paolo

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2019  Volume 45, Issue 9, Page(s) 1536–1541

    Abstract: Despite strong hereditary components, most cases of colorectal cancer are sporadic. The possibility to manipulate in the clinical setting the many presumed risk factors is almost impossible, and long-term epidemiological studies are the only reliable ... ...

    Abstract Despite strong hereditary components, most cases of colorectal cancer are sporadic. The possibility to manipulate in the clinical setting the many presumed risk factors is almost impossible, and long-term epidemiological studies are the only reliable form for comparisons. We performed a systematic review to analyze the reports of de-novo adenocarcinoma arising in the transposed colon, used for conduit after esophagectomy, after total gastrectomy, and for vaginal reconstruction. In all these situations, the colon is transposed in different physiological conditions from its natural environment. We excluded patients in whom the colon was transposed as urinary conduit because the well known carcinogenic effect of the contact with urine. Overall 45 patients were identified with a de-novo adenocarcinoma arising in the transposed colon (36 after esophagectomy; 1 after total gastrectomy; 8 as neovagina). The only common risk factor in these different anatomic position was the possibility of active or chronic inflammation. There was not a close correlation between time after implantation and occurrence of the carcinoma. The occurrence of the de novo carcinoma was related to ageing, supporting the hypothesis of a major role of inflammation in facilitating deregulation of the immune system, associated with ageing.
    MeSH term(s) Adenocarcinoma/pathology ; Colon/transplantation ; Colonic Neoplasms/pathology ; Esophagectomy ; Female ; Gastrectomy ; Humans ; Inflammation/pathology ; Male ; Neoplasm Staging ; Postoperative Complications/pathology ; Vagina/surgery
    Language English
    Publishing date 2019-05-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2019.05.012
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    Zs.MO 549: Show issues

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