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Article ; Online: Expenses related with a well organized information about risk factors for stroke reduce mortality and burden, with diminished total health expenses.

Sterpetti, Antonio V / Sapienza, Paolo / Borrelli, Valeria

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

2023 Volume 32, Issue 12, Page(s) 107397

MeSH term(s)	Humans ; Stroke/diagnosis ; Stroke/therapy ; Cost of Illness ; Risk Factors ; Health Expenditures
Language	English
Publishing date	2023-09-30
Publishing country	United States
Document type	Letter
ZDB-ID	1131675-5
ISSN	1532-8511 ; 1052-3057
ISSN (online)	1532-8511
ISSN	1052-3057
DOI	10.1016/j.jstrokecerebrovasdis.2023.107397
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Zs.A 3519: Show issues

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Article ; Online: An invited commentary on 'Survival outcomes of neoadjuvant therapy followed by radical resection versus upfront surgery for stage I-III pancreatic ductal adenocarcinoma: a retrospective cohort study'.

Coppola, Alessandro / Iannone, Immacolata / Sapienza, Paolo

International journal of surgery (London, England)

2023 Volume 109, Issue 11, Page(s) 3692–3693

MeSH term(s)	Humans ; Neoadjuvant Therapy ; Retrospective Studies ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/surgery ; Carcinoma, Pancreatic Ductal/drug therapy ; Carcinoma, Pancreatic Ductal/surgery ; Pancreatectomy ; Survival Rate ; Pancreatic Neoplasms
Language	English
Publishing date	2023-11-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2212038-5
ISSN	1743-9159 ; 1743-9191
ISSN (online)	1743-9159
ISSN	1743-9191
DOI	10.1097/JS9.0000000000000607
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Zs.A 6502: Show issues

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Article ; Online: Letter to the Editor on Endovascular Revascularization with Stent Implantation in Patients with Acute Mesenteric Ischemia due to Acute Arterial Thrombosis: Clinical Outcome and Predictive Factors.

Lauro, Augusto / Sapienza, Paolo

Cardiovascular and interventional radiology

2021 Volume 44, Issue 12, Page(s) 2011–2012

MeSH term(s)	Acute Disease ; Endovascular Procedures ; Humans ; Mesenteric Ischemia/diagnostic imaging ; Mesenteric Ischemia/surgery ; Mesenteric Vascular Occlusion/diagnostic imaging ; Mesenteric Vascular Occlusion/surgery ; Retrospective Studies ; Stents ; Thrombosis/diagnostic imaging ; Treatment Outcome ; Vascular Surgical Procedures
Language	English
Publishing date	2021-08-13
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	603082-8
ISSN	1432-086X ; 0342-7196 ; 0174-1551
ISSN (online)	1432-086X
ISSN	0342-7196 ; 0174-1551
DOI	10.1007/s00270-021-02942-x
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Zs.A 1378: Show issues

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Article ; Online: Reduced levels of atmospheric levels of PM 2.5 and simultaneous decrease of hospital admissions for cardiovascular emergencies in Italy.

Gabriele, Raimondo / Iannone, Iammacolata / Sapienza, Paolo / DI Marzo, Luca / Sterpetti, Antonio V

International journal of cardiology. Cardiovascular risk and prevention

2024 Volume 20, Page(s) 200241

Language	English
Publishing date	2024-02-01
Publishing country	Netherlands
Document type	Journal Article
ISSN	2772-4875
ISSN (online)	2772-4875
DOI	10.1016/j.ijcrp.2024.200241
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Article ; Online: Mortality and burden related with aortic aneurysms and dissections. The importance of information and education.

Sterpetti, Antonio V / Gabriele, Raimondo / Sapienza, Paolo / Marzo, Luca Di / Borrelli, Valeria

Current problems in cardiology

2024 Volume 49, Issue 3, Page(s) 102384

Abstract: Background: In this study we correlated changes of risk factors for cardiovascular diseases with trends of age standardized mortality rates and burden for aortic aneurysms and dissections.: Methods: We analyzed data from the Global Burden of Diseases ...

Abstract	Background: In this study we correlated changes of risk factors for cardiovascular diseases with trends of age standardized mortality rates and burden for aortic aneurysms and dissections. Methods: We analyzed data from the Global Burden of Diseases and EUROSTAT. Findings: There was a significant increase of expenditure for health from 1980 and 2019. In the period 1980-2000, despite higher health spending, age standardized mortality rates increased in almost all European countries. During the period 2000-2019, in Western European Countries and in Poland, Estonia, Latvia, Slovenia there was a correlation between higher health expenditure and decrease of ASMR. The most important changes between the period 1980-2000 and the period 2000-2019 was the proportion of health expenditure devoted to preventive care and to the increased use of aspirin and statins. Interpretation: Information about risk factors for cardiovascular diseases have leads to decreased aortic aneurysm related mortality and burden.
MeSH term(s)	Humans ; Aortic Aneurysm ; Estonia ; Aspirin ; Risk Factors ; Dissection
Chemical Substances	Aspirin (R16CO5Y76E)
Language	English
Publishing date	2024-01-04
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	441230-8
ISSN	1535-6280 ; 0146-2806
ISSN (online)	1535-6280
ISSN	0146-2806
DOI	10.1016/j.cpcardiol.2024.102384
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Article ; Online: The role of education and information to prevent trends towards increase of cardiovascular mortality rates in Europe from 2015 TO 2019.

Sterpetti, Antonio V / Gabriele, Raimondo / Iannone, Immacolata / Sapienza, Paolo / Marzo, Luca Di

Current problems in cardiology

2024 Volume 49, Issue 3, Page(s) 102415

Abstract: Background: In Europe Cardio Vascular Disease (CVD) mortality rates decreased significantly in the last 25 years, with less decline in the last 5 years. The aim of our study was to analyze trends of risk factors which may explain plateauing of CVD ... ...

Abstract	Background: In Europe Cardio Vascular Disease (CVD) mortality rates decreased significantly in the last 25 years, with less decline in the last 5 years. The aim of our study was to analyze trends of risk factors which may explain plateauing of CVD mortality rates in the period 2015-2019 in Europe. Methods: We analyzed data from the Global Burden Disease and EUROSTAT concerning trends of CVD mortality rates for 25 European countries and simultaneous changes of exposure to risk factors of the population RESULTS: CVD related mortality decreased significantly in the analyzed countries in the period 2000-2015; in the period 2015-2019 there was a trend towards plateauing of CVD related mortality rates, which was associated with an increased exposure to several established risk factors including cigarette smoking, obesity and arterial hypertension. A decrease in expenditure for information, education and counseling programs was documented in most countries in the same period. Level of exposure to risk factors was correlated with educational attainment . Exposure to risk factors in the interval 2014-2019 increased for people with lower education, whereas decreased in people with higher education (p<0.001). Conclusions: Organized information about risk factors for CVD have the potential to reduce mortality and burden, with diminished total health expenses. Education and information in this setting should consider the cultural and social level of the public.
MeSH term(s)	Humans ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Educational Status ; Europe/epidemiology ; Risk Factors ; Hypertension
Language	English
Publishing date	2024-01-20
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	441230-8
ISSN	1535-6280 ; 0146-2806
ISSN (online)	1535-6280
ISSN	0146-2806
DOI	10.1016/j.cpcardiol.2024.102415
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Article ; Online: Reduced carotid revascularization and screening for asymptomatc patients during the COVID-19 pandemic in Italy.

Sterpetti, Antonio V / Di Marzo, Luca / Sapienza, Paolo / Gabriele, Raimondo / Borrelli, Valeria

Journal of vascular surgery

2024 Volume 79, Issue 4, Page(s) 988–990

MeSH term(s)	Humans ; COVID-19 ; Pandemics/prevention & control ; Carotid Stenosis ; Vascular Surgical Procedures ; Italy/epidemiology
Language	English
Publishing date	2024-02-17
Publishing country	United States
Document type	Letter
ZDB-ID	605700-7
ISSN	1097-6809 ; 0741-5214
ISSN (online)	1097-6809
ISSN	0741-5214
DOI	10.1016/j.jvs.2023.12.007
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Zs.A 1933: Show issues

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Article ; Online: Clinical outcomes for patients with cardiovascular diseases before, during, and after the COVID19 pandemic. A pooled analysis of 600.000 patients.

Sterpetti, Antonio V / Gabriele, Raimondo / Borrelli, Valeria / Campagnol, Monica / Iannone, Immacolata / Costi, Umberto / Sapienza, Paolo / Dimarzo, Luca

Current problems in cardiology

2024 Volume 49, Issue 6, Page(s) 102540

Abstract: Background: The unexpected virulence of the COVID19 pandemic brought to significant changes of generally accepted therapeutic approaches. The consequences of these changes were difficult to define during the pandemic period.: Methods: We analyzed the ...

Abstract	Background: The unexpected virulence of the COVID19 pandemic brought to significant changes of generally accepted therapeutic approaches. The consequences of these changes were difficult to define during the pandemic period. Methods: We analyzed the National Registries including 97% of hospital admissions in Italy, regarding data describing number of operations for aortic valve implantation or repair, carotid and coronary revascularization, AAA repair, and lower limb arterial reconstruction performed in the period 2015 to 2019 and in the pandemic years 2020, 2021, and 2022. Primary outcomes were number and type of surgical procedures, 30-days operative mortality. Results: During the three years of the pandemic there was a statistically significant increase of the number of all-causes deaths in comparison with the mean of the previous five years (2015-2019). In Italy there was a total increase of all causes-deaths of 251.911 (+105900 in 2020; +66929 in 2021; and +79082 in 2022), and 73% of the excess of deaths was related with COVID19 infection and 27% occurred in COVID 19 negative patients. During the first year of the pandemic, worse clinical outcomes for hospitalized patients with CVD were registered. The medical system responded adequately and in the following two pandemic years clinical outcomes for hospitalized patients were similar with those of the pre-pandemic period. Conclusions: The unexpected virulence of COVID19 pandemic determined worse clinical outcomes for patients with CVD during the first year. The adopted preventive measures allowed in the following two pandemic years improved clinical outcomes, similar with those of the pre-pandemic period.
Language	English
Publishing date	2024-03-21
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	441230-8
ISSN	1535-6280 ; 0146-2806
ISSN (online)	1535-6280
ISSN	0146-2806
DOI	10.1016/j.cpcardiol.2024.102540
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Article ; Online: Adenocarcinoma in the transposed colon: High grade active inflammation versus low grade chronic inflammation.

Sterpetti, Antonio V / Sapienza, Paolo

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

2019 Volume 45, Issue 9, Page(s) 1536–1541

Abstract: Despite strong hereditary components, most cases of colorectal cancer are sporadic. The possibility to manipulate in the clinical setting the many presumed risk factors is almost impossible, and long-term epidemiological studies are the only reliable ... ...

Abstract	Despite strong hereditary components, most cases of colorectal cancer are sporadic. The possibility to manipulate in the clinical setting the many presumed risk factors is almost impossible, and long-term epidemiological studies are the only reliable form for comparisons. We performed a systematic review to analyze the reports of de-novo adenocarcinoma arising in the transposed colon, used for conduit after esophagectomy, after total gastrectomy, and for vaginal reconstruction. In all these situations, the colon is transposed in different physiological conditions from its natural environment. We excluded patients in whom the colon was transposed as urinary conduit because the well known carcinogenic effect of the contact with urine. Overall 45 patients were identified with a de-novo adenocarcinoma arising in the transposed colon (36 after esophagectomy; 1 after total gastrectomy; 8 as neovagina). The only common risk factor in these different anatomic position was the possibility of active or chronic inflammation. There was not a close correlation between time after implantation and occurrence of the carcinoma. The occurrence of the de novo carcinoma was related to ageing, supporting the hypothesis of a major role of inflammation in facilitating deregulation of the immune system, associated with ageing.
MeSH term(s)	Adenocarcinoma/pathology ; Colon/transplantation ; Colonic Neoplasms/pathology ; Esophagectomy ; Female ; Gastrectomy ; Humans ; Inflammation/pathology ; Male ; Neoplasm Staging ; Postoperative Complications/pathology ; Vagina/surgery
Language	English
Publishing date	2019-05-15
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	632519-1
ISSN	1532-2157 ; 0748-7983
ISSN (online)	1532-2157
ISSN	0748-7983
DOI	10.1016/j.ejso.2019.05.012
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Zs.A 1149: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Occurrence of Colorectal Cancer After a Negative Colonoscopy in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.

Scotti, Giorgia Burrelli / Iannone, Immacolata / DE Padua, Cristina / Crocetti, Daniele / Fiori, Giulia / Sapienza, Paolo / Fiori, Enrico / Avenia, Stefano / Lamazza, Antonietta

In vivo (Athens, Greece)

2024 Volume 38, Issue 2, Page(s) 523–530

Abstract: Background/aim: Despite the application of colorectal cancer (CRC) surveillance guidelines, the detection of early neoplastic lesions might be difficult in patients with inflammatory bowel disease (IBD). To explore the risk of post-colonoscopy CRC ( ... ...

Abstract	Background/aim: Despite the application of colorectal cancer (CRC) surveillance guidelines, the detection of early neoplastic lesions might be difficult in patients with inflammatory bowel disease (IBD). To explore the risk of post-colonoscopy CRC (PCCRC) in patients with IBD we performed a systematic review and meta-analysis. Patients and methods: A systematic literature search was performed (PROSPERO; no. CRD42023453049). We included studies reporting the 3-year PCCRC (PCCRC-3y) prevalence, according to World Endoscopy Organization (WEO)-endorsed definition, in IBD and non-IBD patients. As primary outcome we evaluated the PCCRC-3y prevalence, according to WEO definitions, in IBD- and non-IBD patients and calculated the odds ratio (OR). The secondary outcome was to assess risk factors for PCCRC development in IBD patients. Results: Three retrospective observational cohort studies were included. The pooled PCCRC-3y rate in patients with IBD was 30.8% [95% confidence interval (CI)=24.4-37.5%] and in non-IBD patients was 6.8% (95%CI=6.2-7.4%). The PCCRC-3y occurrence in IBD patients was significantly higher than that in non-IBD patients (OR=6.04; 95%CI=4.04-9.4; I Conclusion: One-third of CRC in IBD patients were PCCRC, and these numbers were significantly higher when compared with those in non-IBD patients. Furthermore, the prevalence of PCCRC in patients with UC was higher compared to those with CD. However, prospective studies are required to better characterize risk factors for PCCRC development in patients with IBD.
MeSH term(s)	Humans ; Retrospective Studies ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/pathology ; Colonoscopy/adverse effects ; Inflammatory Bowel Diseases/complications ; Inflammatory Bowel Diseases/diagnosis ; Inflammatory Bowel Diseases/epidemiology ; Colitis, Ulcerative/diagnosis ; Colitis, Ulcerative/epidemiology ; Colitis, Ulcerative/complications ; Crohn Disease/complications ; Risk Factors
Language	English
Publishing date	2024-02-27
Publishing country	Greece
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	807031-3
ISSN	1791-7549 ; 0258-851X
ISSN (online)	1791-7549
ISSN	0258-851X
DOI	10.21873/invivo.13470
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