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  1. Article ; Online: Connecting Communities through a Translational Focus

    Sara Hamilton

    Cell Reports Medicine, Vol 1, Iss 1, Pp 100008- (2020)

    2020  

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A look back at our first year

    Sara Hamilton / Isabel Goldman / Kristan van der Vos / Sha Yu / Yixin Yao

    Cell Reports Medicine, Vol 2, Iss 4, Pp 100259- (2021)

    2021  

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Experts by Experience: Qualitative Evaluation of Adolescent Participation in the Development of a Technological Intervention to Prevent Youth Suicide in Chile.

    Schilling, Sara Hamilton / Carreño, Alejandra / Tapia, Eric / Mascayano, Franco / Pitronello, Romina / Santander, Felipe / Jorquera, María José / Burrone, María Soledad / Alvarado, Ruben Vladimir

    Frontiers in psychiatry

    2021  Volume 11, Page(s) 522057

    Abstract: Adolescent suicide is a pressing problem in Chile that has not yet been sufficiently addressed, as suicide rates have stagnated in recent years. One possible explanation could be linked to the adult-centered paradigm that continues to prevail in relation ...

    Abstract Adolescent suicide is a pressing problem in Chile that has not yet been sufficiently addressed, as suicide rates have stagnated in recent years. One possible explanation could be linked to the adult-centered paradigm that continues to prevail in relation to adolescent health initiatives. In light of this, programs that seek to promote youth mental health should consider incorporating adolescents in the design process using participatory methodologies, to ensure that these initiatives are well-suited for the population. In line with this recommendation, a group of seven adolescents, 13 to 20 years of age, were incorporated into a research team to actively guide the design, development, and validation of a technology-based intervention, known as Project Clan, which was piloted to reduce adolescent suicide in schools in Chile. This group was known as the "Group of Experts," in acknowledgment of their role as experts by experience on adolescence. A qualitative case study was conducted to explore their lived experiences, through semistructured individual in-depth interviews with six members of the group. Results showed that the adolescents had a high level of interest in mental health and had experienced problems of their own or accompanied friends who were struggling, which motivated their participation in the study. They had a critical view of the previous interventions they had received through educational institutions and valued their role in the promotion of their peers' mental health through the Group of Experts. They also highlighted the importance of creating tools that complement their daily lives and provide an alternative to existing social networks, by respecting their anonymity, providing a secure place for divulgation and self-expression, and facilitating access to professional support. We conclude that programs that address issues that affect adolescents should incorporate adolescents in the decision-making and design processes to ensure the acceptability and effectivity of their interventions.
    Language English
    Publishing date 2021-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2020.522057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A Review of the Opportunities and Challenges for Using Remote Sensing for Management of Surface-Canopy Forming Kelps

    Kyle C. Cavanaugh / Tom Bell / Maycira Costa / Norah E. Eddy / Lianna Gendall / Mary G. Gleason / Margot Hessing-Lewis / Rebecca Martone / Meredith McPherson / Ondine Pontier / Luba Reshitnyk / Rodrigo Beas-Luna / Mark Carr / Jennifer E. Caselle / Katherine C. Cavanaugh / Rebecca Flores Miller / Sara Hamilton / Walter N. Heady / Heidi K. Hirsh /
    Rietta Hohman / Lynn Chi Lee / Julio Lorda / James Ray / Daniel C. Reed / Vienna R. Saccomanno / Sarah B. Schroeder

    Frontiers in Marine Science, Vol

    2021  Volume 8

    Abstract: Surface-canopy forming kelps provide the foundation for ecosystems that are ecologically, culturally, and economically important. However, these kelp forests are naturally dynamic systems that are also threatened by a range of global and local pressures. ...

    Abstract Surface-canopy forming kelps provide the foundation for ecosystems that are ecologically, culturally, and economically important. However, these kelp forests are naturally dynamic systems that are also threatened by a range of global and local pressures. As a result, there is a need for tools that enable managers to reliably track changes in their distribution, abundance, and health in a timely manner. Remote sensing data availability has increased dramatically in recent years and this data represents a valuable tool for monitoring surface-canopy forming kelps. However, the choice of remote sensing data and analytic approach must be properly matched to management objectives and tailored to the physical and biological characteristics of the region of interest. This review identifies remote sensing datasets and analyses best suited to address different management needs and environmental settings using case studies from the west coast of North America. We highlight the importance of integrating different datasets and approaches to facilitate comparisons across regions and promote coordination of management strategies.
    Keywords kelp forest ; remote sensing ; North America ; coastal management ; kelp management ; bull kelp ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Subject code 333
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression

    Zhenyue Hao / Yi Sheng / Gordon S. Duncan / Wanda Y. Li / Carmen Dominguez / Jennifer Sylvester / Yu-Wen Su / Gloria H.Y. Lin / Bryan E. Snow / Dirk Brenner / Annick You-Ten / Jillian Haight / Satoshi Inoue / Andrew Wakeham / Alisha Elford / Sara Hamilton / Yi Liang / Juan C. Zúñiga-Pflücker / Housheng Hansen He /
    Pamela S. Ohashi / Tak W. Mak

    Nature Communications, Vol 8, Iss 1, Pp 1-

    2017  Volume 14

    Abstract: The E3 ligase Mule has been previously reported to be essential for B cell development and function by modulating p53 ubiquitination and degradation. Here Haoet al. identify KLF4 as a novel ubiquitination target of Mule and show it controls T cell ... ...

    Abstract The E3 ligase Mule has been previously reported to be essential for B cell development and function by modulating p53 ubiquitination and degradation. Here Haoet al. identify KLF4 as a novel ubiquitination target of Mule and show it controls T cell proliferation and autoimmunity.
    Keywords Science ; Q
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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