Article ; Online: The presence of extra chromosomes leads to genomic instability
Nature Communications, Vol 7, Iss 1, Pp 1-
2016 Volume 12
Abstract: One of the hallmarks of cancer cells is aneuploidy, however the molecular effects are poorly understood. Here the authors show that trisomic and tetrasomic cells display increased genomic instability and reduced levels of the helicase MCM2-7. ...
| Abstract | One of the hallmarks of cancer cells is aneuploidy, however the molecular effects are poorly understood. Here the authors show that trisomic and tetrasomic cells display increased genomic instability and reduced levels of the helicase MCM2-7. |
|---|---|
| Keywords | Science ; Q |
| Language | English |
| Publishing date | 2016-02-01T00:00:00Z |
| Publisher | Nature Portfolio |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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