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  1. AU="Sarkis, Rani A"
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  1. Article: Anti-Seizure Medications on Trial Again: Accused of Parkinson's Disease!

    Sarkis, Rani A

    Epilepsy currents

    2023  Volume 23, Issue 5, Page(s) 277–279

    Language English
    Publishing date 2023-06-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.1177/15357597231180068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Update in Progress: Cognitive Phenotypes in Temporal Lobe Epilepsy.

    Sarkis, Rani A

    Epilepsy currents

    2023  Volume 23, Issue 6, Page(s) 363–365

    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.1177/15357597231211446
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Anti-Epileptogenesis: Some Roads Lead to Losartan.

    Sarkis, Rani A

    Epilepsy currents

    2023  Volume 23, Issue 3, Page(s) 159–161

    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.1177/15357597231160607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Levetiracetam in Alzheimer's Disease: Do Epileptologists Already Have the Cure?

    Sarkis, Rani A

    Epilepsy currents

    2022  Volume 22, Issue 4, Page(s) 225–227

    Language English
    Publishing date 2022-07-16
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.1177/15357597221096020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: fMRI to Predict Naming Decline: Can We Improve the Grade From a C to an A?

    Sarkis, Rani A

    Epilepsy currents

    2022  Volume 22, Issue 6, Page(s) 345–347

    Language English
    Publishing date 2022-09-22
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.1177/15357597221126277
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Interictal epileptiform discharges in Alzheimer's disease: prevalence, relevance, and controversies.

    Lemus, Hernan Nicolas / Sarkis, Rani A

    Frontiers in neurology

    2023  Volume 14, Page(s) 1261136

    Abstract: Alzheimer's disease (AD) is the most common type of dementia and remains an incurable, progressive disease with limited disease-modifying interventions available. In patients with AD, interictal epileptiform discharges (IEDs) have been identified in up ... ...

    Abstract Alzheimer's disease (AD) is the most common type of dementia and remains an incurable, progressive disease with limited disease-modifying interventions available. In patients with AD, interictal epileptiform discharges (IEDs) have been identified in up to 54% of combined cohorts of mild cognitive impairment (MCI) or mild dementia and are a marker of a more aggressive disease course. Studies assessing the role of IEDs in AD are limited by the lack of standardization in the definition of IEDs or the different neurophysiologic techniques used to capture them. IEDs are an appealing treatment target given the availability of EEG and anti-seizure medications. There remains uncertainty regarding when to treat IEDs, the optimal drug and dose for treatment, and the impact of treatment on disease course. This review covers the state of knowledge of the field of IEDs in AD, and the steps needed to move the field forward.
    Language English
    Publishing date 2023-09-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2023.1261136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Moving towards core sleep outcomes in neurodegenerative disease-the time is now.

    Sarkis, Rani A / Lucey, Brendan P

    Sleep

    2022  Volume 45, Issue 7

    MeSH term(s) Humans ; Neurodegenerative Diseases/complications ; Sleep ; Sleep Wake Disorders/complications
    Language English
    Publishing date 2022-05-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 424441-2
    ISSN 1550-9109 ; 0161-8105
    ISSN (online) 1550-9109
    ISSN 0161-8105
    DOI 10.1093/sleep/zsac112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Epilepsy care in nursing facilities: Knowledge gaps and opportunities.

    Lemus, Hernan Nicolas / Sarkis, Rani A

    Epilepsy & behavior : E&B

    2022  Volume 138, Page(s) 108997

    Abstract: Epilepsy in the elderly is a complex disease, often underdiagnosed, and inadequately treated. It requires a multi-disciplinary approach and care coordination especially if the patient resides in a nursing facility. Episodes of loss of consciousness falls, ...

    Abstract Epilepsy in the elderly is a complex disease, often underdiagnosed, and inadequately treated. It requires a multi-disciplinary approach and care coordination especially if the patient resides in a nursing facility. Episodes of loss of consciousness falls, or amnestic events in those living in a nursing facility require a detailed description and an urgent assessment to rule out an epileptic seizure. Prompt recognition of seizures and the implementation of treatment protocols in those with recurrent seizures are needed to prevent unnecessary emergency visits. Although there is a myriad of antiseizure medications (ASM) to treat seizures, clinicians should be aware of common interactions, side effects, and changes in pharmacodynamics with age. There is a limited number of ASMs that have been properly studied in clinical trials to assess tolerability and efficacy in the elderly, and an over-reliance on enzyme-inducing ASMs. Strategies to improve the knowledge of health care providers include electronic resources, treatment protocols, and improving awareness of the efficacy, drug-drug interaction, and short-term and long-term monitoring of ASM side effects.
    MeSH term(s) Aged ; Humans ; Epilepsy/diagnosis ; Epilepsy/drug therapy ; Seizures ; Epilepsy, Generalized ; Drug-Related Side Effects and Adverse Reactions ; Consciousness ; Anticonvulsants/therapeutic use
    Chemical Substances Anticonvulsants
    Language English
    Publishing date 2022-11-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2022.108997
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Risk of Neuroleptic Malignant Syndrome in Encephalitides: Response to Caroff.

    Sarkis, Rani A

    The Journal of neuropsychiatry and clinical neurosciences

    2019  Volume 31, Issue 4, Page(s) 400

    MeSH term(s) Anti-N-Methyl-D-Aspartate Receptor Encephalitis ; Antipsychotic Agents ; Catatonia ; Humans ; Neuroleptic Malignant Syndrome ; Phenotype ; United States
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2019-10-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1036340-3
    ISSN 1545-7222 ; 0895-0172
    ISSN (online) 1545-7222
    ISSN 0895-0172
    DOI 10.1176/appi.neuropsych.18120392r
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: On epilepsy and education: Challenges faced when compiling global research.

    Chemali, Zeina / Gifford, Abbott / Sarkis, Rani A

    Epilepsy & behavior : E&B

    2023  Volume 144, Page(s) 109263

    MeSH term(s) Humans ; Epilepsy ; Educational Status
    Language English
    Publishing date 2023-05-31
    Publishing country United States
    Document type Editorial
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2023.109263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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