LIVIVO - Search results -

Search results

Result 1 - 10 of total 14

Search options

Article ; Online: Attenuation of quorum sensing mediated virulence factors production and biofilm formation in Pseudomonas aeruginosa PAO1 by Colletotrichum gloeosporioides HM3.

Meena, Himani / Mishra, Rashmi / Ranganathan, Sampathkumar / Sarma, V Venkateswara / Ampasala, Dinakara Rao / Siddhardha, Busi

Microbial pathogenesis

2021 Volume 151, Page(s) 104723

Abstract: Signal dependent microbial communication in Pseudomonas aeruginosa PAO1 is a typical phenomenon mediated by acyl homo-serine lactone molecules that helps in developing biofilm and enhance antibiotic resistance. Microbial sources provide insight to the ... ...

Abstract	Signal dependent microbial communication in Pseudomonas aeruginosa PAO1 is a typical phenomenon mediated by acyl homo-serine lactone molecules that helps in developing biofilm and enhance antibiotic resistance. Microbial sources provide insight to the hidden treasure of secondary metabolites, and these structurally diversified chemical motifs can be used as antimicrobial and anti-infective agents. In the present study, endophytic fungus, Colletotrichum gloeosporioides HM3 isolated from Carica papaya leaves was explored for anti-infective potential against P. aeruginosa PAO1. The crude extract of C. gloeosporioides HM3 displayed bacteriostatic effect on P. aeruginosa PAO1 growth at 750 μg/ml concentration. A significant decline was observed in the production of quorum sensing regulated virulence factors, i.e. 56.32%, 62.54%, and 66.67% of pyocyanin, chitinase, and elastase enzyme, respectively. A drastic reduction in pathogenic determinant behaviour after treatment with crude extract of C. gloeosporioides HM3 i.e. EPS, rhamnolipid, and HCN production was noted. Light microscopy and CLSM analysis revealed that fungal extract treatment has reduced bacterial ability to form dense biofilm architecture. In silico analysis demonstrated the binding efficiency of bioactive compound, 4-(2,3-dimethoxybenzylidene)-3-methyl-1-(4-nitrophenyl)-2-pyrazolin-5-one, which is equipotent to the natural ligand and displayed a docking score of -5.436 kcal/mol with QS transcriptional regulator (LasR). Whereas the compound Acetamide, n-[tetrahydro-3-(phenylmethyl) thieno [3,4-d]thiazol-2 (3 h)-ylidene]-, s,s-dioxide exhibits a docking score of -4.088 kcal/mol (LasR) and -1.868 kcal/mol (RhlR) with cognate receptor proteins. Henceforth, the research report suggests C. gloeosporioides HM3 derived metabolites could be considered as a potential inhibitors of QS regulated virulence factors and biofilm production in P. aeruginosa PAO1.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/genetics ; Bacterial Proteins/pharmacology ; Biofilms ; Colletotrichum ; Pseudomonas aeruginosa ; Quorum Sensing ; Virulence ; Virulence Factors/genetics
Chemical Substances	Anti-Bacterial Agents ; Bacterial Proteins ; Virulence Factors
Language	English
Publishing date	2021-01-16
Publishing country	England
Document type	Journal Article
ZDB-ID	632772-2
ISSN	1096-1208 ; 0882-4010
ISSN (online)	1096-1208
ISSN	0882-4010
DOI	10.1016/j.micpath.2020.104723
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2136: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Inhibition of quorum sensing-associated virulence factors and biofilm formation in Pseudomonas aeruginosa PAO1 by Mycoleptodiscus indicus PUTY1.

Ahmed, Tanveer / Pattnaik, Subhaswaraj / Khan, Mohd Babu / Ampasala, Dinakara Rao / Busi, Siddhardha / Sarma, V Venkateswara

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology

2020 Volume 51, Issue 2, Page(s) 467–487

Abstract: Pseudomonas aeruginosa is the second most emerging multidrug-resistant, opportunistic pathogen after Acinetobacter baumannii that poses a threat in nursing homes, hospitals, and patients who need devices such as ventilators and blood catheters. Its ... ...

Abstract	Pseudomonas aeruginosa is the second most emerging multidrug-resistant, opportunistic pathogen after Acinetobacter baumannii that poses a threat in nursing homes, hospitals, and patients who need devices such as ventilators and blood catheters. Its ability to form quorum sensing-regulated virulence factors and biofilm makes it more resistant to top most therapeutic agents such as carbapenems and next-generation antibiotics. In the current study, we studied the quorum quenching potential of secondary metabolites of Mycoleptodiscus indicus PUTY1 strain. In vitro observation showed a mitigation in virulence factors such as rhamnolipids, protease, elastase pyocyanin, exopolysaccharides, and hydrogen cyanide gas. Furthermore, a significant reduction in the motility such as swimming, swarming, twitching, and inhibition in biofilm formation by Pseudomonas aeruginosa PAO1 was observed. Results of in vitro studies were further confirmed by in silico studies through docking and molecular dynamic simulation of GC-MS-detected compounds of Mycoleptodiscus indicus employing LasR and RhlR proteins. Both in vitro and in silico observations indicate a new alternative approach for combating virulence of Pseudomonas aeruginosa by targeting its protein receptors LasR and RhlR. Graphical abstract.
MeSH term(s)	Ascomycota/chemistry ; Biofilms/drug effects ; Microbial Sensitivity Tests ; Molecular Dynamics Simulation ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/physiology ; Quorum Sensing/drug effects ; Secondary Metabolism ; Virulence Factors/antagonists & inhibitors
Chemical Substances	Virulence Factors
Language	English
Publishing date	2020-02-21
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2017175-4
ISSN	1678-4405 ; 1517-8382
ISSN (online)	1678-4405
ISSN	1517-8382
DOI	10.1007/s42770-020-00235-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Vittaliana mangrovei Devadatha, Nikita, A.Baghela & V.V.Sarma, gen. nov, sp. nov. (Phaeosphaeriaceae), from Mangroves Near Pondicherry (India), Based on Morphology and Multigene Phylogeny

Devadatha, Bandarupalli / Mehta, Nikita / Wanasinghe, Dhanushka N / Baghela, Abhishek / Sarma, V. Venkateswara

Cryptogamie. 2019 Nov. 8, v. 40, no. 7

2019

Abstract: Collection and examination of decaying wood samples of Avicennia marina (Forssk.) Vierh. from Pondicherry mangroves, India, resulted in the discovery of a novel monotypic genus Vittaliana, based on the type species V. mangrovei, which shares close ... ...

Abstract	Collection and examination of decaying wood samples of Avicennia marina (Forssk.) Vierh. from Pondicherry mangroves, India, resulted in the discovery of a novel monotypic genus Vittaliana, based on the type species V. mangrovei, which shares close morphological affinities with Italica Wanas., Camporesi & K.D.Hyde and Phaeosphaeriopsis M.P.S. Câmara, M.E. Palm & A.W. Ramaley. The concatenated LSU, SSU, TEF1α and ITS multigene phylogenetic analyses revealed that the new genus clustered together with Italica as a sister clade but forms a separate branch. In addition, morphological variations in Vittaliana mangrovei Devadatha, Nikita, A.Baghela & V.V.Sarma, gen. nov., sp. nov., such as semi-immersed, globose to subglobose ascomata, 5-6 distoseptate, phragmosporous, yellow to golden-yellow ascospores lacking a mucilaginous sheath and any type of ornamentation, and which are strongly constricted at the 4th septum, clearly delineate the new genus from the other genera in Phaeosphaeriaceae. Furthermore, Vittaliana Devadatha, Nikita, A.Baghela & V.V.Sarma, gen. nov., is saprobic and occurs in marine environment. Morphological characteristics and phylogenetic relation of our new species are discussed by comparing with closely related genera in Phaeosphaeriaceae.
Keywords	Avicennia marina ; Phaeosphaeriaceae ; ascomata ; ascospores ; decayed wood ; internal transcribed spacers ; marine environment ; new genus ; new species ; phylogeny ; ribosomal DNA ; saprophytes ; India
Language	English
Dates of publication	2019-1108
Size	p. 117-132.
Publishing place	Association des Amis des Cryptogames
Document type	Article
ISSN	1776-100X
DOI	10.5252/cryptogamiemycologie2019v40a7
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Anti-quorum sensing and antibiofilm activities of Blastobotrys parvus PPR3 against Pseudomonas aeruginosa PAO1

Parasuraman, Paramanantham / Ampasala, Dinakara Rao / Devadatha, B / Ranganathan, Sampathkumar / Sarma, V. Venkateswara / Siddhardha, Busi

Microbial pathogenesis. 2019 Oct. 18,

2019

Abstract: The bacterial cell communication also termed as Quorum sensing (QS) system was involved in the expression of several virulence traits during Pseudomonas infection. The attenuating of this bacterial cell communication system is an attractive approach for ... ...

Abstract	The bacterial cell communication also termed as Quorum sensing (QS) system was involved in the expression of several virulence traits during Pseudomonas infection. The attenuating of this bacterial cell communication system is an attractive approach for the management of bacterial infections without the complication of resistance development. In this respect, the marine environment has gained significant attention due to its biodiversity and as a source of novel bioactive compounds. The present study aimed to screening effective QS inhibitors from marine associated fungal species for QS inhibitors. Twelve morphologically distinct fungal isolates were isolated from the wood of Avicennia marina from marine ecosystem. The anti-QS potential of fungal crude extract from was investigated in biosensor strain and test bacterium, Chromobacterium violaceum and Pseudomonas aeruginosa PAO1, respectively. Promising anti-QS activity was observed in the crude extract of one of the fungal isolate and identified by molecular characterization using internal transcribed spacer (ITS) region as Blastobotrys parvus PPR3. The anti-virulence and antibiofilm effects of ethyl acetate fractions from PPR3 against P. aeruginosa PAO1 were evaluated. The fungal metabolites responsible for the anti-QS activity of fungal crude extract was identified using gas chromatography-mass spectrometry (GC-MS). Furthermore, molecular docking studies were performed to understand the interaction of bioactive compounds with as receptors of P. aeruginosa PAO1. The crude extract of PPR3 showed reduction in different virulence traits of P. aeruginosa PAO1 such as production of pyocyanin, elastase, protease, chitinase, swimming and swarming motility, biofilm formation, exopolysaccharide production and alginate production at different sub-MIC concentrations. Interaction of bioactive metabolites with LasR and RhlR receptors of P. aeruginosa PAO1 was reported. The findings of the present study suggested that metabolites of B. parvus PPR3 interfere with QS system of P. aeruginosa PAO1 and alters the production of virulence factors.
Keywords	alginates ; antimicrobial properties ; Avicennia marina ; bacteria ; bacterial infections ; bacterial motility ; bioactive compounds ; biodiversity ; biofilm ; biosensors ; Blastobotrys ; cell communication ; chitinase ; Chromobacterium violaceum ; communications technology ; computer simulation ; elastase ; ethyl acetate ; exopolysaccharides ; fungi ; gas chromatography-mass spectrometry ; internal transcribed spacers ; marine ecosystems ; marine environment ; metabolites ; Pseudomonas aeruginosa ; pyocyanin ; quorum sensing ; receptors ; screening ; swimming ; virulence ; wood
Language	English
Dates of publication	2019-1018
Publishing place	Elsevier Ltd
Document type	Article
Note	Pre-press version
ZDB-ID	632772-2
ISSN	1096-1208 ; 0882-4010
ISSN (online)	1096-1208
ISSN	0882-4010
DOI	10.1016/j.micpath.2019.103811
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 2136: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Ecology and Evolution of Marine Fungi With Their Adaptation to Climate Change.

Kumar, Vinit / Sarma, V Venkateswara / Thambugala, Kasun M / Huang, Jun-Jie / Li, Xiang-Yang / Hao, Ge-Fei

Frontiers in microbiology

2021 Volume 12, Page(s) 719000

Abstract: Climate change agitates interactions between organisms and the environment and forces them to adapt, migrate, get replaced by others, or extinct. Marine environments are extremely sensitive to climate change that influences their ecological functions and ...

Abstract	Climate change agitates interactions between organisms and the environment and forces them to adapt, migrate, get replaced by others, or extinct. Marine environments are extremely sensitive to climate change that influences their ecological functions and microbial community including fungi. Fungi from marine habitats are engaged and adapted to perform diverse ecological functions in marine environments. Several studies focus on how complex interactions with the surrounding environment affect fungal evolution and their adaptation. However, a review addressing the adaptation of marine fungi to climate change is still lacking. Here we have discussed the adaptations of fungi in the marine environment with an example of
Language	English
Publishing date	2021-08-27
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2021.719000
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Anti-quorum sensing and antibiofilm activities of Blastobotrys parvus PPR3 against Pseudomonas aeruginosa PAO1.

Parasuraman, Paramanantham / Devadatha, B / Sarma, V Venkateswara / Ranganathan, Sampathkumar / Ampasala, Dinakara Rao / Siddhardha, Busi

Microbial pathogenesis

2019 Volume 138, Page(s) 103811

Abstract	The bacterial cell communication also termed as Quorum sensing (QS) system was involved in the expression of several virulence traits during Pseudomonas infection. The attenuating of this bacterial cell communication system is an attractive approach for the management of bacterial infections without the complication of resistance development. In this respect, the marine environment has gained significant attention due to its biodiversity and as a source of novel bioactive compounds. The present study aimed to screening effective QS inhibitors from marine associated fungal species for QS inhibitors. Twelve morphologically distinct fungal isolates were isolated from the wood of Avicennia marina from marine ecosystem. The anti-QS potential of fungal crude extract from was investigated in biosensor strain and test bacterium, Chromobacterium violaceum and Pseudomonas aeruginosa PAO1, respectively. Promising anti-QS activity was observed in the crude extract of one of the fungal isolate and identified by molecular characterization using internal transcribed spacer (ITS) region as Blastobotrys parvus PPR3. The anti-virulence and antibiofilm effects of ethyl acetate fractions from PPR3 against P. aeruginosa PAO1 were evaluated. The fungal metabolites responsible for the anti-QS activity of fungal crude extract was identified using gas chromatography-mass spectrometry (GC-MS). Furthermore, molecular docking studies were performed to understand the interaction of bioactive compounds with as receptors of P. aeruginosa PAO1. The crude extract of PPR3 showed reduction in different virulence traits of P. aeruginosa PAO1 such as production of pyocyanin, elastase, protease, chitinase, swimming and swarming motility, biofilm formation, exopolysaccharide production and alginate production at different sub-MIC concentrations. Interaction of bioactive metabolites with LasR and RhlR receptors of P. aeruginosa PAO1 was reported. The findings of the present study suggested that metabolites of B. parvus PPR3 interfere with QS system of P. aeruginosa PAO1 and alters the production of virulence factors.
MeSH term(s)	Anti-Bacterial Agents/biosynthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Antibiosis ; Aquatic Organisms ; Biofilms/drug effects ; Biofilms/growth & development ; Gas Chromatography-Mass Spectrometry ; Microbial Sensitivity Tests ; Models, Molecular ; Phylogeny ; Pseudomonas aeruginosa/physiology ; Quorum Sensing/drug effects ; Saccharomycetales/classification ; Saccharomycetales/isolation & purification ; Saccharomycetales/physiology ; Structure-Activity Relationship ; Virulence/drug effects
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2019-10-20
Publishing country	England
Document type	Journal Article
ZDB-ID	632772-2
ISSN	1096-1208 ; 0882-4010
ISSN (online)	1096-1208
ISSN	0882-4010
DOI	10.1016/j.micpath.2019.103811
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2136: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Aspergillus ochraceopetaliformis SSP13 modulates quorum sensing regulated virulence and biofilm formation in Pseudomonas aeruginosa PAO1.

Pattnaik, Subhaswaraj / Ahmed, Tanveer / Ranganathan, Sampath Kumar / Ampasala, Dinakara Rao / Sarma, V Venkateswara / Busi, Siddharha

Biofouling

2018 Volume 34, Issue 4, Page(s) 410–425

Abstract: Pseudomonas aeruginosa is an opportunistic nosocomial pathogen causing the majority of acute and persistent infections in human beings. The ability to form biofilm adds a new dimension to its resistance to conventional therapeutic agents. In the present ... ...

Abstract	Pseudomonas aeruginosa is an opportunistic nosocomial pathogen causing the majority of acute and persistent infections in human beings. The ability to form biofilm adds a new dimension to its resistance to conventional therapeutic agents. In the present study, down-regulation of quorum sensing regulated virulence and biofilm development resulting from exposure to Aspergillus ochraceopetaliformis SSP13 extract was investigated. The in vitro results inferred impairment in the production of LasA protease, LasB elastase, chitinase, pyocyanin, exopolysaccharides and rhamnolipids. In addition, motility and biofilm formation by P. aeruginosa PAO1 was significantly altered. The in vitro results were further supported by molecular docking studies of the metabolites obtained from GC-MS analysis depicting the quorum sensing attenuation by targeting the receptor proteins LasR and RhlR. The in vitro and in silico studies suggested new avenues for the development of bioactive metabolites from A. ochraceopetaliformis SSP13 extract as potential anti-infective agents.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Aspergillus/chemistry ; Bacterial Proteins/genetics ; Biofilms/growth & development ; Chitinases/genetics ; Gene Expression Regulation, Bacterial ; Glycolipids ; Molecular Docking Simulation ; Peptide Hydrolases/genetics ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/metabolism ; Pseudomonas aeruginosa/physiology ; Pyocyanine/genetics ; Quorum Sensing/drug effects ; Virulence
Chemical Substances	Anti-Bacterial Agents ; Bacterial Proteins ; Glycolipids ; rhamnolipid ; Pyocyanine (9OQM399341) ; Chitinases (EC 3.2.1.14) ; Peptide Hydrolases (EC 3.4.-)
Language	English
Publishing date	2018-05-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1029-2454
ISSN (online)	1029-2454
DOI	10.1080/08927014.2018.1460748
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Phomopsis tersa as Inhibitor of Quorum Sensing System and Biofilm Forming Ability of Pseudomonas aeruginosa

Meena, Himani / Mishra, Rashmi / Ranganathan, Sampathkumar / Sarma, V. Venkateswara / Ampasala, Dinakara Rao / Kalia, Vipin Chandra / Lee, Jung-Kul / Siddhardha, Busi

Indian journal of microbiology. 2020 Mar., v. 60, no. 1

2020

Abstract: Endophytic fungi provide rich reservoir for novel antimicrobial compounds. An endophytic fungus, from Carica papaya plant identified as Phomopsis tersa, was investigated for attenuating the quorum sensing mediated pathogenicity of Pseudomonas aeruginosa ... ...

Abstract	Endophytic fungi provide rich reservoir for novel antimicrobial compounds. An endophytic fungus, from Carica papaya plant identified as Phomopsis tersa, was investigated for attenuating the quorum sensing mediated pathogenicity of Pseudomonas aeruginosa PAO1. Crude extract of P. tersa was found to reduce the production of redox-active pigments—pyocyanin and pyoverdine in P. aeruginosa PAO1 by 92.46% and 71.55%, respectively at sub-MIC concentration of 900 μg/mL. In addition, the crude extract was also able to inhibit the expression of virulence factors involved in biofilm formation: exopolysaccharide (72.21%) and alginate (72.50%). Secretion of cell-lytic enzymes was also found to be reduced: chitinase by 79.73% and elastase by 74.30%. 3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione identified from GC-MS analysis, displayed favorable molecular interactions with P. aeruginosa transcriptional regulators, LasR and RhlR with good docking scores of − 6.873 kJ/mol and − 6.257 kJ/mol, respectively. The study thus reveals the potential use of P. tersa for discovering drugs against infectious pathogens.
Keywords	Carica papaya ; Diaporthe ; Pseudomonas aeruginosa ; alginates ; anti-infective agents ; biofilm ; chitinase ; drugs ; elastase ; endophytes ; exopolysaccharides ; fungi ; gas chromatography-mass spectrometry ; pathogens ; pyoverdines ; quorum sensing ; secretion ; transcription factors ; virulence
Language	English
Dates of publication	2020-03
Size	p. 70-77.
Publishing place	Springer India
Document type	Article
ZDB-ID	413422-9
ISSN	0973-7715 ; 0046-8991
ISSN (online)	0973-7715
ISSN	0046-8991
DOI	10.1007/s12088-019-00840-y
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 2617: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Phomopsis tersa

Meena, Himani / Mishra, Rashmi / Ranganathan, Sampathkumar / Sarma, V Venkateswara / Ampasala, Dinakara Rao / Kalia, Vipin Chandra / Lee, Jung-Kul / Siddhardha, Busi

Indian journal of microbiology

2019 Volume 60, Issue 1, Page(s) 70–77

Abstract: Endophytic fungi provide rich reservoir for novel antimicrobial compounds. An endophytic fungus, ... ...

Abstract	Endophytic fungi provide rich reservoir for novel antimicrobial compounds. An endophytic fungus, from
Language	English
Publishing date	2019-11-16
Publishing country	India
Document type	Journal Article
ZDB-ID	413422-9
ISSN	0973-7715 ; 0046-8991
ISSN (online)	0973-7715
ISSN	0046-8991
DOI	10.1007/s12088-019-00840-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2617: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Inhibition of Microbial Quorum Sensing Mediated Virulence Factors by

Parasuraman, Paramanantham / Devadatha, B / Sarma, V Venkateswara / Ranganathan, Sampathkumar / Ampasala, Dinakara Rao / Reddy, Dhanasekhar / Kumavath, Ranjith / Kim, In-Won / Patel, Sanjay K S / Kalia, Vipin Chandra / Lee, Jung-Kul / Siddhardha, Busi

Journal of microbiology and biotechnology

2020 Volume 30, Issue 4, Page(s) 571–582

Abstract: Quorum sensing (QS)-mediated infections cause severe diseases in human beings. The control of infectious diseases by inhibiting QS using antipathogenic drugs is a promising approach as antibiotics are proving inefficient in treating these diseases. ... ...

Abstract	Quorum sensing (QS)-mediated infections cause severe diseases in human beings. The control of infectious diseases by inhibiting QS using antipathogenic drugs is a promising approach as antibiotics are proving inefficient in treating these diseases. Marine fungal (
MeSH term(s)	Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Biofilms/drug effects ; Biofilms/growth & development ; Gene Expression Regulation, Bacterial/drug effects ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Pestalotiopsis/metabolism ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/pathogenicity ; Pseudomonas aeruginosa/physiology ; Quorum Sensing/drug effects ; Virulence/drug effects ; Virulence/genetics ; Virulence Factors/genetics ; Virulence Factors/metabolism
Chemical Substances	Anti-Bacterial Agents ; Bacterial Proteins ; RhlR protein, Pseudomonas aeruginosa ; Virulence Factors
Language	English
Publishing date	2020-01-23
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2412195-2
ISSN	1738-8872 ; 1017-7825
ISSN (online)	1738-8872
ISSN	1017-7825
DOI	10.4014/jmb.1907.07030
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito