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Article ; Online: Severe Hypoplasia of Paranasal Sinuses and Turbinates.

Saro-Buendía, Miguel / Gómez-Gómez, Maria José / Armengot-Carceller, Miguel

JAMA otolaryngology-- head & neck surgery

2024

Language	English
Publishing date	2024-04-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2701825-8
ISSN	2168-619X ; 2168-6181
ISSN (online)	2168-619X
ISSN	2168-6181
DOI	10.1001/jamaoto.2024.0674
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Article: Objective Tinnitus Secondary to Palatal Tremor: Two Case Reports.

Acosta, Raul Mellidez / Saro-Buendía, Miguel / García, Lidia Torres / Antonia, Maria / Vernetta, Carlos De Paula

The international tinnitus journal

2022 Volume 25, Issue 2, Page(s) 129–132

Abstract: Tinnitus is defined as a tinnitus perceived both by the patient and external observers. This category represents 1.5% of the total amount of tinnitus evaluated in tertiary healthcare institutions. ...

Abstract	Tinnitus is defined as a tinnitus perceived both by the patient and external observers. This category represents 1.5% of the total amount of tinnitus evaluated in tertiary healthcare institutions.
MeSH term(s)	Humans ; Tinnitus/complications ; Tinnitus/etiology ; Tremor/complications ; Tremor/etiology
Language	English
Publishing date	2022-03-03
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1402694-6
ISSN	0946-5448
ISSN	0946-5448
DOI	10.5935/0946-5448.20210023
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Zs.A 5435: Show issues

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Article ; Online: Posterior Lingual Abscess; Report of Two Cases.

Saro-Buendía, Miguel / Suarez Urquiza, Pedro / Amigo González, Judit / Lesmas Navarro, Maria José / Mazón, Miguel / Armengot Carceller, Miguel

Archives of academic emergency medicine

2023 Volume 11, Issue 1, Page(s) e18

Abstract: The lingual abscess is rare due to several protective mechanisms against infection in this location. Concretely, the abscess in the base of the tongue (posterior lingual abscess) is even more exceptional. Its prompt detection is crucial to avoid ... ...

Abstract	The lingual abscess is rare due to several protective mechanisms against infection in this location. Concretely, the abscess in the base of the tongue (posterior lingual abscess) is even more exceptional. Its prompt detection is crucial to avoid potentially fatal airway complications. To familiarize physicians with this condition, we report 2 cases of posterior lingual abscess. Both were referred to our emergency department due to minor oropharyngeal complaints. Finally, both were diagnosed and required surgical drainage. The clinical evolution was successful: both were discharged in less than 72 hours and follow-up one week later confirmed clinical recovery.
Language	English
Publishing date	2023-01-14
Publishing country	Iran
Document type	Case Reports
ISSN	2645-4904
ISSN (online)	2645-4904
DOI	10.22037/aaem.v11i1.1860
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Article: Fallopian Canal Meningocele Causing Cerebrospinal Fluid Rhinorrhoea.

Saro-Buendía, Miguel / Torres-García, Lidia / Almanzo, Santiago / Mora Aristizabal, Daniel Felipe / de Paula Vernetta, Carlos / Armengot Carceller, Miguel

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2023 Volume 75, Issue 4, Page(s) 3945–3948

Abstract: Fallopian canal meningocele is an extremely rare cause of cerebrospinal fluid rhinorrhoea. Also, due to complex anatomical relations and a lack of experience, its management remains a challenge. Here we report a case focusing on its clinical course, ... ...

Abstract	Fallopian canal meningocele is an extremely rare cause of cerebrospinal fluid rhinorrhoea. Also, due to complex anatomical relations and a lack of experience, its management remains a challenge. Here we report a case focusing on its clinical course, radiological features, and management.
Language	English
Publishing date	2023-06-21
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-023-03963-3
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Article: Labyrinthine Bifurcation of the Facial Nerve.

Saro-Buendía, Miguel / Mellidez Acosta, Raúl / Bancalari Díaz, Catalina / Mazón, Miguel / de Paula Vernetta, Carlos / Armengot Carceller, Miguel

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2023 Volume 75, Issue 4, Page(s) 4086–4089

Abstract: The labyrinthine bifurcation of the facial nerve is extremely rare. Diverse congenital temporal bone anomalies usually coexist, and a detailed preoperative evaluation is needed to detect them. We report a case of labyrinthine bifurcation of the facial ... ...

Abstract	The labyrinthine bifurcation of the facial nerve is extremely rare. Diverse congenital temporal bone anomalies usually coexist, and a detailed preoperative evaluation is needed to detect them. We report a case of labyrinthine bifurcation of the facial nerve detected on the preoperative evaluation of a patient with congenital aural atresia.
Language	English
Publishing date	2023-07-15
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-023-03977-x
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Article ; Online: Management of iodine contrast induced salivary gland swelling (sialadenitis): experiences from an observational study.

Saro-Buendía, Miguel / Torres-García, Lidia / Mossi Martínez, Claudia / Battig Arriagada, Eduardo / Carreres Polo, Joan / Perolada Valmaña, José María / Armengot Carceller, Miguel

Acta oto-laryngologica

2023 Volume 143, Issue 1, Page(s) 64–69

Abstract: Background: Iodine contrast-induced sialadenitis (CIS) is an uncommon adverse effect to iodine-containing contrast exposition. There is scarce literature about its clinical course and demography.: Objectives: (1) To determine the clinical course and ... ...

Abstract	Background: Iodine contrast-induced sialadenitis (CIS) is an uncommon adverse effect to iodine-containing contrast exposition. There is scarce literature about its clinical course and demography. Objectives: (1) To determine the clinical course and management of CIS. (2) To understand if CIS might be as rare as reported. Material and methods: A 2-month prospective observational study was conducted in the emergency room of a tertiary institution. ENT physicians on call received clinical formation about CIS while emergency physicians did not. During the study period, patients admitted at the emergency room matching the clinical and radiological features of CIS, were included. Information about demographics, iodine exposure, diagnostic workup, clinical course, and management was analyzed. Results: ENT physicians on call detected 4 cases, however, emergency physicians did not. Patients were aged 68-76 years and presented a bilateral submandibular gland swelling debuting 12 to 72 h after an exposure to iodinated contrast. Characteristic ultrasonographic findings supported the diagnosis and the clinical course was self-limited after 60 to 150 h. Conclusions and significance: Physicians' familiarity with CIS allows its detection and avoids costly and potentially harmful therapeutic/diagnostic efforts. The incidence is probably underestimated; however, further incidence studies are needed.
MeSH term(s)	Humans ; Iodine/adverse effects ; Sialadenitis/diagnosis ; Sialadenitis/diagnostic imaging ; Contrast Media/adverse effects ; Salivary Glands ; Disease Progression ; Submandibular Gland
Chemical Substances	Iodine (9679TC07X4) ; Contrast Media
Language	English
Publishing date	2023-01-03
Publishing country	England
Document type	Observational Study ; Journal Article
ISSN	1651-2251
ISSN (online)	1651-2251
DOI	10.1080/00016489.2022.2162121
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Article ; Online: Objective tinnitus secondary to palatal tremor: Two case reports and brief literature review.

Mellidez Acosta, Raúl / Saro-Buendía, Miguel / Torres García, Lidia / Marcos Peña, Maria Antonia / De Paula Vernetta, Carlos

Journal of otology

2021 Volume 17, Issue 2, Page(s) 107–110

Abstract: Objective tinnitus is defined as a type of tinnitus perceived by both the patient and external observer. This paper presents two cases of objective tinnitus related to palatal tremor, along with a literature review. Palatal tremor is a condition ... ...

Abstract	Objective tinnitus is defined as a type of tinnitus perceived by both the patient and external observer. This paper presents two cases of objective tinnitus related to palatal tremor, along with a literature review. Palatal tremor is a condition characterized by soft palate involuntary contractions. Two types of palatal tremor have been described: symptomatic palatal tremor and essential palatal tremor, with different clinical manifestations. Diagnostic workup is based on medical history and physical examination, including direct oropharynx exploration and cavum visualization through nasopharyngoscopy. Brain MRI is mandatory in all cases. If a secondary origin is suspected, additional lab tests should be performed based on clinical suspicion. First-line treatment is botulinum toxin injection into the
Language	English
Publishing date	2021-11-29
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2621477-5
ISSN	2524-1753 ; 1672-2930
ISSN (online)	2524-1753
ISSN	1672-2930
DOI	10.1016/j.joto.2021.11.003
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Article ; Online: Implementation of a program to improve influenza vaccination rates among medical students: a comparative study involving two university affiliated hospitals.

Saro-Buendía, Miguel / Marrero-Sánchez, Ángel / García-Ruiz de Morales, Daniel / Chiara-Graciani, Guillermo / Coderch-Carretero, Jaime / Pérez-Jacoiste Asín, María Asunción / Silva, José Tiago / Fernández-Ruiz, Mario / Arrazola, Pilar / Aguado, José María / López-Medrano, Francisco

Human vaccines & immunotherapeutics

2021 Volume 17, Issue 10, Page(s) 3662–3669

Abstract: Background and ... ...

Abstract	Background and objectives
MeSH term(s)	Attitude of Health Personnel ; Cross-Sectional Studies ; Health Personnel ; Hospitals, University ; Humans ; Influenza Vaccines ; Influenza, Human/prevention & control ; Students, Medical ; Vaccination
Chemical Substances	Influenza Vaccines
Language	English
Publishing date	2021-06-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2664176-8
ISSN	2164-554X ; 2164-5515
ISSN (online)	2164-554X
ISSN	2164-5515
DOI	10.1080/21645515.2021.1920269
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Article ; Online: Combination therapy with tocilizumab and corticosteroids for aged patients with severe COVID-19 pneumonia: A single-center retrospective study.

López-Medrano, Francisco / Pérez-Jacoiste Asín, María Asunción / Fernández-Ruiz, Mario / Carretero, Octavio / Lalueza, Antonio / Maestro de la Calle, Guillermo / Caro, José Manuel / de la Calle, Cristina / Catalán, Mercedes / García-García, Rocío / Martínez-López, Joaquín / Origüen, Julia / Ripoll, Mar / San Juan, Rafael / Trujillo, Hernando / Sevillano, Ángel / Gutiérrez, Eduardo / de Miguel, Borja / Aguilar, Fernando /

Gómez, Carlos / Silva, José Tiago / García-Ruiz de Morales, Daniel / Saro-Buendía, Miguel / Marrero-Sánchez, Ángel / Chiara-Graciani, Guillermo / Bueno, Héctor / Paz-Artal, Estela / Lumbreras, Carlos / Pablos, José L / Aguado, José María

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2021 Volume 105, Page(s) 487–494

Abstract: Background: The role of combination immunomodulatory therapy with systemic corticosteroids and tocilizumab (TCZ) for aged patients with COVID-19-associated cytokine release syndrome remains unclear.: Methods: A retrospective single-center study was ... ...

Abstract	Background: The role of combination immunomodulatory therapy with systemic corticosteroids and tocilizumab (TCZ) for aged patients with COVID-19-associated cytokine release syndrome remains unclear. Methods: A retrospective single-center study was conducted on consecutive patients aged ≥65 years who developed severe COVID-19 between 03 March and 01 May 2020 and were treated with corticosteroids at various doses (methylprednisolone 0.5mg/kg/12h to 250mg/24h), either alone (CS group) or associated with intravenous tocilizumab (400-600mg, one to three doses) (CS-TCZ group). The primary outcome was all-cause mortality by day +14, whereas secondary outcomes included mortality by day +28 and clinical improvement (discharge and/or a ≥2 point decrease on a 6-point ordinal scale) by day +14. Propensity score (PS)-based adjustment and inverse probability of treatment weights (IPTW) were applied. Results: Totals of 181 and 80 patients were included in the CS and CS-TCZ groups, respectively. All-cause 14-day mortality was lower in the CS-TCZ group, both in the PS-adjusted (hazard ratio [HR]: 0.34; 95% confidence interval [CI]: 0.17-0.68; P=0.002) and IPTW-weighted models (odds ratio [OR]: 0.38; 95% CI: 0.21-0.68; P=0.001). This protective effect was also observed for 28-day mortality (PS-adjusted HR: 0.38; 95% CI: 0.21-0.72; P=0.003). Clinical improvement by day +14 was higher in the CS-TCZ group with IPTW analysis only (OR: 2.26; 95% CI: 1.49-3.41; P<0.001). The occurrence of secondary infection was similar between both groups. Conclusions: The combination of corticosteroids and TCZ was associated with better outcomes among patients aged ≥65 years with severe COVID-19.
MeSH term(s)	Aged ; Aged, 80 and over ; Antibodies, Monoclonal, Humanized/administration & dosage ; COVID-19/drug therapy ; Drug Therapy, Combination ; Female ; Humans ; Male ; Methylprednisolone/administration & dosage ; Middle Aged ; Retrospective Studies ; SARS-CoV-2
Chemical Substances	Antibodies, Monoclonal, Humanized ; tocilizumab (I031V2H011) ; Methylprednisolone (X4W7ZR7023)
Language	English
Publishing date	2021-02-26
Publishing country	Canada
Document type	Journal Article
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2021.02.099
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Article ; Online: Combination therapy with tocilizumab and corticosteroids for aged patients with severe COVID-19 pneumonia: a single-center retrospective study.

Lopez-Medrano, Francisco / Perez-Jacoiste Asin, Maria Asuncion / Fernandez-Ruiz, Mario / Carretero, Octavio / Lalueza, Antonio / Maestro de la Calle, Guillermo / Caro, Jose Manuel / de la Calle, Cristina / Catalan, Mercedes / Garcia Garcia, Rocio / Martinez-Lopez, Joaquin / Origuen, Julia / Ripoll, Mar / San Juan, Rafael / Trujillo, Hernando / Sevillano, Angel / Gutierrez, Eduardo / de Miguel, Borja / Aguilar, Fernando /

Gomez, Carlos / Silva, Jose Tiago / Garcia-Ruiz de Morales, Daniel / Saro-Buendia, Miguel / Marrero-Sanchez, Angel / Chiara-Graciani, Guillermo / Bueno, Hector / Paz-Artal, Estela / Lumbreras, Carlos / Pablos, Jose Luis / Aguado, Jose Maria

medRxiv

Abstract: Background: The role of combination immunomodulatory therapy with systemic corticosteroids and tocilizumab (TCZ) for aged patients with COVID19 associated cytokine release syndrome remains unclear. Methods: We conducted a retrospective single center ... ...

Abstract	Background: The role of combination immunomodulatory therapy with systemic corticosteroids and tocilizumab (TCZ) for aged patients with COVID19 associated cytokine release syndrome remains unclear. Methods: We conducted a retrospective single center study including consecutive patients older than 65 years that developed severe COVID19 between March 3 and May 1, 2020 and were treated with corticosteroids at various doses (methylprednisolone [0.5 mg/Kg/12 hours to 250 mg/24 hours]), either alone (CS group) or associated to intravenous tocilizumab (400 to 600 mg, one to three doses) (CS/TCZ group). Primary outcome was all cause mortality by day +14, whereas secondary outcomes included mortality by day +28 and clinical improvement (discharge and/or a 2 point decrease on a six point ordinal scale) by day +14. Propensity score (PS)based adjustment and inverse probability of treatment weights (IPTW) were applied. Results: Overall, 181 and 80 patients were included in the CS and CS TCZ groups. All cause 14 day mortality was lower in the CS/TCZ group, both in the PS adjusted (hazard ratio [HR]: 0.34; 95% confidence interval [CI]: 0.17 to 0.68; P value = 0.002) and IPTW weighted models (odds ratio [OR]: 0.38; 95% CI: 0.21 to 0.68; P value = 0.001). This protective effect was also observed for 28 day mortality (PS adjusted HR: 0.38; 95% CI: 0.21 to 0.72; P value = 0.003). Clinical improvement by day +14 was higher in the CS/TCZ group in the IPTW analysis only (OR: 2.26; 95% CI: 1.49 to 3.41; P value <0.001). The occurrence of secondary infection was similar between both groups. Conclusions: The combination of corticosteroids and TCZ was associated with better outcomes among patients older than 65 years with severe COVID-19.
Keywords	covid19
Language	English
Publishing date	2020-09-30
Publisher	Cold Spring Harbor Laboratory Press
Document type	Article ; Online
DOI	10.1101/2020.09.26.20202283
Database	COVID19

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