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Article ; Online: Effects of Low Dose Dexamethasone as an Adjuvant to Levobupivacaine in Ultrasound-guided Interscalene Brachial Plexus Block

Simpika Thakur / Sarvjeet Kaur / Amanjot Singh / Jaspreet Kaur

Journal of Clinical and Diagnostic Research, Vol 17, Iss 1, Pp UC27-UC

A Randomised Clinical Trial

2023 Volume 30

Abstract: Introduction: Ultrasound-guided Interscalene Brachial (USG-ISB) plexus block is known to provide effective analgesia for upper limbs surgery. Low-dose dexamethasone as additive with levobupivacaine in USG-ISB plexus block is known to provide effective ... ...

Abstract	Introduction: Ultrasound-guided Interscalene Brachial (USG-ISB) plexus block is known to provide effective analgesia for upper limbs surgery. Low-dose dexamethasone as additive with levobupivacaine in USG-ISB plexus block is known to provide effective analgesia for upper limbs surgery. Aim: To evaluate whether dexamethasone, use as an additive with levobupivacaine during an USG-ISB plexus block for upper limb surgery, has sufficient analgesic effect. Materials and Methods: The randomised clinical trial was conducted at GGS Medical College and Hospital, Faridkot, Punjab, India, from March 2018 to August 2019. Sixty patients who were scheduled to have upper limb surgery using USG-ISB with 0.5% levobupivacaine were randomly assigned to one of two groups. Group A (n=30) received one ml of normal saline, while group B (n=30) received 4 mg of dexamethasone. A four-point Verbal Numerical Rating Scale (VNRS) for pain was used to evaluate postoperative analgesia. The duration of analgesia, time to onset and duration of sensory and motor blockade, and pain ratings were measured. Unpaired student's t-test, Chi-square and Fisher’s-exact tests were used to analyse the data. Results: The mean duration of analgesia was significantly longer for group B than for group A (854.67±10.08 min vs 743.00±23.22 min; p-value<0.001). The onset of sensory and motor blocks in group B began to develop earlier (8.42±0.35 min, and 9.72±0.55 min) than those in group A (10.10±0.80 min, and 11.02±0.84 min; p-value<0.001). The duration of the sensory and motor block in group B was longer (653±16.17 min and 582.83±14.18 min) than that in group A (595±17.29 min and 487.33±21.04 min; p-value<0.001). Conclusion: Perineural dexamethasone with levobupivacaine provides greater postoperative analgesia, also speed up the onset of sensory and motor effects, and prolongs the duration of interscalene brachial plexus block.
Keywords	analgesia ; perineural ; surgery ; Medicine ; R
Subject code	796
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Biopsychosocial determinant of quality of life of older adults in Pakistan and Canada.

Batool, Syeda Shahida / Tanveer, Samra / Chatrath, Sarvjeet Kaur / Batool, Syeda Azra

Frontiers in psychiatry

2024 Volume 15, Page(s) 1364443

Abstract: Background: The rapidly rising average age of the older adults has brought various global healthcare challenges. A core challenge is how to enhance their quality of life (QoL).: Objective: The objective of the current study was to test the ... ...

Abstract	Background: The rapidly rising average age of the older adults has brought various global healthcare challenges. A core challenge is how to enhance their quality of life (QoL). Objective: The objective of the current study was to test the significance of biopsychosocial determinants of quality of life of older adults in Pakistan and Canada. Methodology: A cross-sectional survey was carried out on a conveniently approached purposive sample of 1,005 older adults (Pakistani = 557 and Canadian = 448) of age range between 60 years and 80 years. The data were collected via demographic datasheet, World Health Organization Quality of Life Brief Scale, Health and Lifestyle Questionnaire, General Self-Efficacy Scale, Rosenberg Self-Esteem Scale, and Berlin Social Support Scale. Results: The results of hierarchical regression analysis showed that biopsychosocial factors ( Conclusion: A significant amount of better QoL of older adults can be achieved through enhancing the biopsychosocial correlates of their QoL, both in Pakistan and Canada.
Language	English
Publishing date	2024-03-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2024.1364443
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparative evaluation of propofol versus dexmedetomidine infusion for hypotensive anesthesia during functional endoscopic sinus surgery

Kewal Krishan Gupta / Vandana Kumari / Sarvjeet Kaur / Amanjot Singh

Anesthesia and Pain Medicine, Vol 17, Iss 3, Pp 271-

a prospective randomized trial

2022 Volume 279

Abstract: Background During functional endoscopic sinus surgery (FESS), intranasal bleeding affects operative field visibility and increases the frequency of complications. Therefore, hypotensive anesthesia is a widely used technique to improve surgical outcomes. ... ...

Abstract	Background During functional endoscopic sinus surgery (FESS), intranasal bleeding affects operative field visibility and increases the frequency of complications. Therefore, hypotensive anesthesia is a widely used technique to improve surgical outcomes. This study aimed to compare the efficacy of propofol and dexmedetomidine infusion for hypotensive anesthesia in patients undergoing FESS. Methods This prospective randomized trial was conducted in 80 adult patients who were scheduled for FESS under general anesthesia. Patients were randomly divided into two groups: group P (n = 40) received propofol infusion of 100–200 µg/kg/min and group D (n = 40) received dexmedetomidine infusion with a loading dose of 1 µg/kg over 10 min after induction, followed by maintenance infusion of 0.4–0.8 µg/kg/h. Intraoperative blood loss, quality of the surgical field (Fromme– Boezaart scale), hemodynamic control, and patient recovery were recorded. Statistical analysis was performed using Student’s t-test, chi-square test, and Mann– Whitney U test. Results The mean arterial pressure and heart rate were significantly lower in group D throughout the surgery than in group P. Blood loss was significantly higher in group P (100.73 ± 18.12 ml) than in group D (85.70 ± 18.56 ml). The average number of patients with Fromme’s score 1/2/3 was comparable between the groups. Intraoperatively, only one incidence of bradycardia and hypotension was observed in group D (2.5%) compared to group P. Conclusions Both dexmedetomidine and propofol are efficacious and safe drugs for facilitating controlled hypotension during FESS; however, dexmedetomidine provides better hemodynamic control and is associated with lesser blood loss without any significant adverse effects.
Keywords	dexmedetomidine ; induced hypotension ; functional endoscopic sinus surgery ; propofol ; Anesthesiology ; RD78.3-87.3 ; Medicine ; R
Subject code	610
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	Korean Society of Anesthesiologists
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Exploring Dynamic Nexus between Economic Growth, Environmental Degradation, and Public Health in Pakistan

Rehana Firdous / Sarvjeet Kaur Chatrath / Atif Khan Jadoon / Munawar Iqbal / Syeda Azra Batool / Zameer Ul Hasan

International Journal of Energy Economics and Policy, Vol 13, Iss

A Moderated Mediation Approach

2023 Volume 1

Abstract: Since the start of this century, much attention has been given to economic growth and environmental changes and their effects on human beings. The present study has developed a comprehensive model to discuss the nexus between economic growth, ... ...

Abstract	Since the start of this century, much attention has been given to economic growth and environmental changes and their effects on human beings. The present study has developed a comprehensive model to discuss the nexus between economic growth, environmental degradation, and public health. Furthermore, renewable energy consumption and public health spending are used as moderators to make the model more inclusive. The time series data from 1972 to 2020 has been used, and a regression path modeling tool SPPS-PROCESS Model 29, has been applied to carry out the results. The results showed a positive and significant effect of economic growth on environmental degradation, while renewable energy consumption reduces environmental degradation. Furthermore, environmental degradation is negatively affecting the health status in Pakistan. The results of the total effects showed that economic growth positively contributes to public health with a low coefficient. The indirect conditional impact of economic growth on human health through the mediating role of environmental degradation becomes positive from negative in the long run due to renewable energy and public spending on health. Based on the result, some policies are suggested in the last section of this study.
Keywords	Economic Growth ; Environmental Degradation ; Health Status ; Public Health Spending ; Renewable Energy ; Environmental sciences ; GE1-350 ; Energy industries. Energy policy. Fuel trade ; HD9502-9502.5
Subject code	339
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EconJournals
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Occurrence of cry Genes in Bacillus thuringiensis (Bt) Isolates Recovered from Phylloplanes of Crops Growing in the New Delhi Region of India and Toxicity Towards Diamond-back Moth ( Plutella xylostella )

Sarvjeet Kaur / S. Jayakumar

Journal of Biological Sciences, Vol 13, Iss 6, Pp 463-

2013 Volume 473

Abstract: Bacillus thuringiensis (Bt) has been used as biopesticide sprays due to its insecticidal specificity but precipitation loss is a limitation. Bt isolates, naturally occurring on crop phylloplanes, have better on-plant persistence. Bt isolates have been ... ...

Abstract	Bacillus thuringiensis (Bt) has been used as biopesticide sprays due to its insecticidal specificity but precipitation loss is a limitation. Bt isolates, naturally occurring on crop phylloplanes, have better on-plant persistence. Bt isolates have been isolated and characterized from phylloplanes of leguminous crops. Bt isolates, which showed presence of highly conserved 16S-23S rRNA internal transcribed spacer region, were screened by PCR for cry gene families. The cry 1 gene family was found to be most abundant, followed by cry 2 gene family, while none of isolates showed presence of cry 3, 4, 7 and 8 gene families. Bt isolates were further screened for presence of specific genes of cry 1 gene family. Four isolates-SK-222, SK-223, SK-229 and SK-232, were found to have cry 1Aa, cry 1Ab, cry 1Ac and cry 1D genes. Isolate SK-222 was found to contain maximum types of genes followed by SK-223, SK-229 and SK-232. Protein profiles of isolates by SDS-PAGE showed 130 kDa band corresponding to cry 1 protein. Isolate SK-223 was most toxic followed by SK-222, SK-229 and SK-232 towards diamondback moth ( Plutella xylostella ) by leaf dip bioassay. Isolates SK-222 and SK-223 were significantly more toxic than Bt subsp. kurstaki (HD1). These isolates have potential of development into biopesticides. Full length cry 1Ab gene was amplified by PCR with specially designed primers from isolate SK-222, cloned and sequenced (GenBank accession No. DQ023297). Sequence analysis showed it to be identical to cry 1Ab18 gene. (http://www.lifesci.sussex.ac.uk/home/Neil_Crickmore/Bt/, GenBank accession No. AY319967) isolated previously from a Bt isolate recovered from soil of Ladakh region in this laboratory.
Keywords	genetic sequence ; Plutella xylostella ; cry gene ; toxicity ; Bacillus thuringiensis ; Biology (General) ; QH301-705.5 ; Science ; Q ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
Language	English
Publishing date	2013-01-01T00:00:00Z
Publisher	Asian Network for Scientific Information
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: IS ECONOMIC GROWTH AND INDUSTRIAL GROWTH THE REASON FOR ENVIRONMENTAL DEGRADATION IN SAARC COUNTRIES

Atif Khan Jadoon / Sania Akhtar / Ambreen Sarwar / Syeda Azra Batool / Sarvjeet Kaur Chatrath / Saima Liaqat

International Journal of Energy Economics and Policy, Vol 11, Iss

2021 Volume 6

Abstract: In the last four decades, the developing countries have built a heavy industrial base which is seen as a threat to the environment. The trade liberalization policies of the SAARC counties led them to increase the production for domestic use and exports. ... ...

Abstract	In the last four decades, the developing countries have built a heavy industrial base which is seen as a threat to the environment. The trade liberalization policies of the SAARC counties led them to increase the production for domestic use and exports. This increase in industrial output is a real threat to environmental degradation as the industrial share is quite significant in the GDP of the SAARC countries. The present study is designed to check the existence of the Environmental Kuznets Curve (EKC) hypothesis and then use industry output as a regressor to see how it is affecting the environment. The panel regression models are used for estimation by taking data from 1980 to 2018. The results are obtained by using Newey-West standard robust errors. The results suggested that there exists a U-shape relationship between economic growth and Carbon Dioxide (CO2) while an inverted U-shape relationship is found between industrial growth and CO2. Furthermore, a unidirectional causality was observed between industrial growth, human capital, energy consumption, and CO2 while bidirectional causality was observed between urbanization and CO2. The present study suggests that there is a need to adopt environmental protection policies related to the industrial sector in the SAARC region. Keywords: Economic Growth, Idustrial Growth, Environmental Degradation JEL Classifications: Q43, Q54, R11 DOI: https://doi.org/10.32479/ijeep.11769
Keywords	Environmental sciences ; GE1-350 ; Energy industries. Energy policy. Fuel trade ; HD9502-9502.5
Subject code	339
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	EconJournals
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: IS ECONOMIC GROWTH AND INDUSTRIAL GROWTH THE REASON FOR ENVIRONMENTAL DEGRADATION IN SAARC COUNTRIES

Atif Khan Jadoon / Sania Akhtar / Ambreen Sarwar / Syeda Azra Batool / Sarvjeet Kaur Chatrath / Saima Liaqat

International Journal of Energy Economics and Policy, Vol 11, Iss

2021 Volume 6

Abstract	In the last four decades, the developing countries have built a heavy industrial base which is seen as a threat to the environment. The trade liberalization policies of the SAARC counties led them to increase the production for domestic use and exports. This increase in industrial output is a real threat to environmental degradation as the industrial share is quite significant in the GDP of the SAARC countries. The present study is designed to check the existence of the Environmental Kuznets Curve (EKC) hypothesis and then use industry output as a regressor to see how it is affecting the environment. The panel regression models are used for estimation by taking data from 1980 to 2018. The results are obtained by using Newey-West standard robust errors. The results suggested that there exists a U-shape relationship between economic growth and Carbon Dioxide (CO2) while an inverted U-shape relationship is found between industrial growth and CO2. Furthermore, a unidirectional causality was observed between industrial growth, human capital, energy consumption, and CO2 while bidirectional causality was observed between urbanization and CO2. The present study suggests that there is a need to adopt environmental protection policies related to the industrial sector in the SAARC region. Keywords: Economic Growth, Idustrial Growth, Environmental Degradation JEL Classifications: Q43, Q54, R11 DOI: https://doi.org/10.32479/ijeep.11769
Keywords	Environmental sciences ; GE1-350 ; Energy industries. Energy policy. Fuel trade ; HD9502-9502.5
Subject code	339
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	EconJournals
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: IS ECONOMIC GROWTH AND INDUSTRIAL GROWTH THE REASON FOR ENVIRONMENTAL DEGRADATION IN SAARC COUNTRIES

Atif Khan Jadoon / Sania Akhtar / Ambreen Sarwar / Syeda Azra Batool / Sarvjeet Kaur Chatrath / Saima Liaqat

International Journal of Energy Economics and Policy, Vol 11, Iss

2021 Volume 6

Abstract	In the last four decades, the developing countries have built a heavy industrial base which is seen as a threat to the environment. The trade liberalization policies of the SAARC counties led them to increase the production for domestic use and exports. This increase in industrial output is a real threat to environmental degradation as the industrial share is quite significant in the GDP of the SAARC countries. The present study is designed to check the existence of the Environmental Kuznets Curve (EKC) hypothesis and then use industry output as a regressor to see how it is affecting the environment. The panel regression models are used for estimation by taking data from 1980 to 2018. The results are obtained by using Newey-West standard robust errors. The results suggested that there exists a U-shape relationship between economic growth and Carbon Dioxide (CO2) while an inverted U-shape relationship is found between industrial growth and CO2. Furthermore, a unidirectional causality was observed between industrial growth, human capital, energy consumption, and CO2 while bidirectional causality was observed between urbanization and CO2. The present study suggests that there is a need to adopt environmental protection policies related to the industrial sector in the SAARC region. Keywords: Economic Growth, Idustrial Growth, Environmental Degradation JEL Classifications: Q43, Q54, R11 DOI: https://doi.org/10.32479/ijeep.11769
Keywords	Environmental sciences ; GE1-350 ; Energy industries. Energy policy. Fuel trade ; HD9502-9502.5
Subject code	339
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	EconJournals
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Pool deconvolution approach for high-throughput gene mining from Bacillus thuringiensis

Panwar, BhupendraS / Chet Ram / Rakesh K Narula / Sarvjeet Kaur

Applied microbiology and biotechnology. 2018 Feb., v. 102, no. 3

2018

Abstract: Novel genes from Bacillus thuringiensis (Bt) are required for effective deployment in agriculture, human health, and forestry. In an improvement over conventional PCR-based screening, next generation sequencing (NGS) has been used for identification of ... ...

Abstract	Novel genes from Bacillus thuringiensis (Bt) are required for effective deployment in agriculture, human health, and forestry. In an improvement over conventional PCR-based screening, next generation sequencing (NGS) has been used for identification of new genes of potential interest from Bt strains, but cost becomes a constraint when several isolates are to be sequenced. We demonstrate the potential of a DNA pooling strategy known as pool deconvolution to identify commercially important toxin genes from 36 native Bt isolates. This strategy is divided into three steps: (a) DNA pooling, (b) short read sequence assembly followed by gene mining, and (c) host isolate identification. With this approach, we have identified insecticidal protein (ip) genes including nine three-domain (3D) cry genes, three cyt-type genes, three mtx genes (mosquitocidal toxin), and one bin and vip-type gene each. Three cry-type and three cyt-type genes were cloned, out of which, two cry-type genes, ip11 and ip13, were named as cry4Ca2 and cry52Ca1, respectively by the Bacillus thuringiensis nomenclature committee (http://www.biols.susx.ac.uk/Home/Neil_Crickmore/BT/). Our results show that the pool deconvolution approach is well suited for high-throughput gene mining in bacteria.
Keywords	Bacillus thuringiensis ; DNA ; bacteria ; bacterial toxins ; crystal proteins ; genes ; genome mining ; high-throughput nucleotide sequencing ; insecticidal proteins ; polymerase chain reaction ; screening
Language	English
Dates of publication	2018-02
Size	p. 1467-1482.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	392453-1
ISSN	1432-0614 ; 0171-1741 ; 0175-7598
ISSN (online)	1432-0614
ISSN	0171-1741 ; 0175-7598
DOI	10.1007/s00253-017-8633-6
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Diversity Analysis of Bacillus thuringiensis Isolates Recovered from Diverse Habitats in India using Random Amplified Polymorphic DNA (RAPD) Markers

Nagendra K. Singh / Rupesh Deshmukh / Jawahar Katara / Sarvjeet Kaur

Journal of Biological Sciences, Vol 13, Iss 6, Pp 514-

2013 Volume 520

Abstract: Bacillus thuringiensis is a bacterium of huge agronomic and scientific interest. The subspecies of this bacterium colonize and kill a large variety of host insects and nematodes with a high degree of specificity. In the present investigation, 32 native ... ...

Abstract	Bacillus thuringiensis is a bacterium of huge agronomic and scientific interest. The subspecies of this bacterium colonize and kill a large variety of host insects and nematodes with a high degree of specificity. In the present investigation, 32 native isolates of Bacillus thuringiensis recovered from different regions in India and 8 known Bacillus thuringiensis strains were analyzed at the molecular level using random amplified polymorphic DNA (RAPD) markers. Seven RAPD markers were used for diversity analysis. The RAPD banding pattern data was subjected to dendrogram construction using Unweighted Pair Group Method with Arithmetic Mean (UPGMA) analysis using NTSYSpc2.2 software. Eight main clusters were formed at 25% similarity level and four isolates were standalone of these clusters. Most of the isolates were found to be diverse, even though they were isolated from the same source or location. The RAPD markers were found to be effective to distinguish B. thuringiensis native isolates recovered from different sources and locations. The results of present investigation help to understand diversity of B. thuringiensis in India, which would be exploited to find new types of B. thuringiensis endotoxins.
Keywords	Bacillus thuringiensis ; diversity ; RAPD markers ; India ; Biology (General) ; QH301-705.5 ; Science ; Q ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
Language	English
Publishing date	2013-01-01T00:00:00Z
Publisher	Asian Network for Scientific Information
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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