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  1. Article: How storytelling through the use of avatars could help Fukushima evacuees express themselves: digital archive for people in the diaspora.

    Sasaki, Kanako

    Medicine, conflict, and survival

    2024  Volume 40, Issue 1, Page(s) 28–43

    Abstract: The Memorytalk online platform allows users to upload animated human stories. They may also choose to display related photos/characters and construct scenarios. Memorytalk may thus constitute a useful collaborative format for survivors of the Great East ... ...

    Abstract The Memorytalk online platform allows users to upload animated human stories. They may also choose to display related photos/characters and construct scenarios. Memorytalk may thus constitute a useful collaborative format for survivors of the Great East Japan Earthquake, especially evacuees from the town of Namie, who are now relocated in different areas across Japan, particularly as they are hesitant to talk about where they are from. This study examined various narrated animations created by Namie high school students within the Memorytalk platform, specifically for the purpose of investigating their storytelling methods based on Erving Goffman's role-distance theory. Memorytalk not only allows avatars that provide users with anonymity when expressing a wide range of memories, it also creates (1) opportunities for face-to-face workshops in the context of computer-mediated communication and (2) the therapeutic benefits of being humorous. In sum, the platform may provide users with a form of role distancing in which people in the diaspora can more freely express themselves and also store valuable local memories.
    MeSH term(s) Humans ; Avatar ; Fukushima Nuclear Accident ; Earthquakes ; Communication ; Human Migration
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1314196-x
    ISSN 1362-3699
    ISSN 1362-3699
    DOI 10.1080/13623699.2024.2306458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2781: Show issues Location:
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  2. Article ; Online: Non-haematological grade 1 and 2 adverse events of frontline CPX-351 in patients with myelodysplastic syndromes.

    Sasaki, Koji

    The Lancet. Haematology

    2023  Volume 10, Issue 11, Page(s) e872

    MeSH term(s) Humans ; Myelodysplastic Syndromes/drug therapy ; Daunorubicin ; Cytarabine ; Leukemia, Myeloid, Acute
    Chemical Substances CPX-351 ; Daunorubicin (ZS7284E0ZP) ; Cytarabine (04079A1RDZ)
    Language English
    Publishing date 2023-10-30
    Publishing country England
    Document type Letter ; Comment
    ISSN 2352-3026
    ISSN (online) 2352-3026
    DOI 10.1016/S2352-3026(23)00272-7
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  3. Article ; Online: Diversity of Japanese consumers' requirements, sensory perceptions, and eating preferences for meat.

    Sasaki, Keisuke

    Animal science journal = Nihon chikusan Gakkaiho

    2022  Volume 93, Issue 1, Page(s) e13705

    Abstract: Japanese consumers are generally characterized as preferring high marbling in beef and pork and choosing domestic products. However, the Japanese food market is not homogenous. Understanding the diversity of Japanese consumers will provide benefits for ... ...

    Abstract Japanese consumers are generally characterized as preferring high marbling in beef and pork and choosing domestic products. However, the Japanese food market is not homogenous. Understanding the diversity of Japanese consumers will provide benefits for the optimization of meat production and distribution in Japan. This article focuses on three factors affecting purchasing decisions and eating satisfaction, namely, requirements, sensory perception, and eating preferences, in order to understand the diversity of Japanese consumers in a simplified manner. Diversity was observed in Japanese consumers in all three of these factors (requirements, perception, and preference) using a questionnaire survey, sensory and biological procedures, and an eating preference test. These diversities are due to not only sociodemographic characteristics but also biological and physiological factors, background culture, and individual attitudes and criteria. Although consumer variation based on sociodemographic characteristics is of course important, it is equally important to understand diversity by focusing on the individual differences among consumers.
    MeSH term(s) Animals ; Cattle ; Consumer Behavior ; Food Preferences ; Japan ; Pork Meat ; Red Meat ; Surveys and Questionnaires
    Language English
    Publishing date 2022-03-10
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2095161-9
    ISSN 1740-0929 ; 1344-3941
    ISSN (online) 1740-0929
    ISSN 1344-3941
    DOI 10.1111/asj.13705
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  4. Article ; Online: Astragalus root increases Treg and Th17 involvement in embryo implantation and pregnancy maintenance by decreasing CTLA-4

    Kobayashi, Kyoko / Sasaki, Kenroh

    Drug discoveries & therapeutics

    2024  Volume 18, Issue 1, Page(s) 24–33

    Abstract: Maintenance of pregnancy is highly dependent on the maternal immune system. High levels of regulatory T cells (Tregs) accumulate in the maternal placenta to suppress immunoreactivity against fetal antigens. We assessed whether Astragalus root (AsR) and ... ...

    Abstract Maintenance of pregnancy is highly dependent on the maternal immune system. High levels of regulatory T cells (Tregs) accumulate in the maternal placenta to suppress immunoreactivity against fetal antigens. We assessed whether Astragalus root (AsR) and AsR-containing Kampo medicines modulate immunoreactivity and thereby increase mouse litter size. AsR-exposed murine splenocytes exhibited significantly increased IL-2 secretion. In AsR-exposed mice, total Tregs were significantly increased, whereas cytotoxic T lymphocyte antigen 4 (CTLA-4)-positive Tregs were decreased in AsR-exposed mice. Tregs express IL-2 receptor subunit alpha and are activated by IL-2. CTLA-4 interacts with B7 expressed in antigen-presenting cells (APCs) with high affinity, and CTLA-4/B7 signaling plays a critical role in inhibiting APC activity, thereby suppressing CD4
    MeSH term(s) Pregnancy ; Female ; Mice ; Animals ; T-Lymphocytes, Regulatory ; CTLA-4 Antigen ; Interleukin-2/pharmacology ; Th17 Cells ; Embryo Implantation ; Pregnancy Maintenance
    Chemical Substances CTLA-4 Antigen ; Interleukin-2
    Language English
    Publishing date 2024-02-21
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2568828-5
    ISSN 1881-784X ; 1881-784X
    ISSN (online) 1881-784X
    ISSN 1881-784X
    DOI 10.5582/ddt.2023.01100
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  5. Article ; Online: Physiological specialization of the brain in bumble bee castes: Roles of dopamine in mating-related behaviors in female bumble bees.

    Morigami, Ayaka / Sasaki, Ken

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0298682

    Abstract: We aimed to investigate the roles of dopamine in regulating caste-specific behaviors in bumble bees and mating-related behaviors in bumble bee gynes. We examined caste differences in behaviors, biogenic amine levels, and expression levels of genes ... ...

    Abstract We aimed to investigate the roles of dopamine in regulating caste-specific behaviors in bumble bees and mating-related behaviors in bumble bee gynes. We examined caste differences in behaviors, biogenic amine levels, and expression levels of genes encoding dopamine receptors in the brains of bumble bees, and analyzed the effects of dopamine-related drugs on bumble bee behavior. Locomotor and flight activities were significantly higher in 8-day-old gynes and light avoidance was significantly lower in 4-8-day-old gynes than in same-aged workers. Brain levels of dopamine and octopamine were significantly higher in 8-day-old gynes than in same-aged workers, but tyramine and serotonin levels did not differ between the castes. Relative expression levels of the dopamine receptor gene BigDop1 were significantly lower in 8-day-old gynes than in same-aged workers, but expression levels of other dopamine receptor genes did not differ between castes. Dopamine significantly enhanced locomotor and flight activities in 7-9-day-old workers, whereas the dopamine receptor antagonist flupentixol inhibited flight activity and mating acceptance in same-aged gynes. These results suggest that dopamine plays important roles in gyne-specific behavior in bumble bees and has a common dopaminergic function in female eusocial bees.
    MeSH term(s) Bees/genetics ; Female ; Animals ; Dopamine/metabolism ; Brain/metabolism ; Biogenic Amines/metabolism ; Reproduction ; Receptors, Dopamine/metabolism
    Chemical Substances Dopamine (VTD58H1Z2X) ; Biogenic Amines ; Receptors, Dopamine
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298682
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  6. Article ; Online: Suppression of Pulsed Dynamic Nuclear Polarization by Many-Body Spin Dynamics.

    Sasaki, Kento / Abe, Eisuke

    Physical review letters

    2024  Volume 132, Issue 10, Page(s) 106904

    Abstract: We study a mechanism by which nuclear hyperpolarization due to the polarization transfer from a microwave-pulse-controlled electron spin is suppressed. From analytical and numerical calculations of the unitary dynamics of multiple nuclear spins, we ... ...

    Abstract We study a mechanism by which nuclear hyperpolarization due to the polarization transfer from a microwave-pulse-controlled electron spin is suppressed. From analytical and numerical calculations of the unitary dynamics of multiple nuclear spins, we uncover that, combined with the formation of the dark state within a cluster of nuclei, coherent higher-order nuclear spin dynamics impose limits on the efficiency of the polarization transfer even in the absence of mundane depolarization processes such as nuclear spin diffusion and relaxation. Furthermore, we show that the influence of the dark state can be partly mitigated by introducing a disentangling operation. Our analysis is applied to the nuclear polarizations observed in ^{13}C nuclei coupled with a single nitrogen-vacancy center in diamond [Randall et al., Science 374, 1474 (2021)SCIEAS0036-807510.1126/science.abk0603]. Our Letter sheds light on collective engineering of nuclear spins as well as future designs of pulsed dynamic nuclear polarization protocols.
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.132.106904
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    In stock of ZB MED Bonn / Germany

    Z 4' 58/153: Show issues

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  7. Article ; Online: Distinct adaptations of muscle endurance but not strength or hypertrophy to low-load resistance training with and without blood flow restriction.

    Ida, Akito / Sasaki, Kazushige

    Experimental physiology

    2024  

    Abstract: Low-load resistance training promotes muscle strength and hypertrophic adaptations when combined with blood flow restriction (BFR). However, the effect of BFR on muscle endurance remains unclear. The aim of this study was to clarify the effects of BFR on ...

    Abstract Low-load resistance training promotes muscle strength and hypertrophic adaptations when combined with blood flow restriction (BFR). However, the effect of BFR on muscle endurance remains unclear. The aim of this study was to clarify the effects of BFR on muscle performance and adaptation, with special reference to local muscle endurance. In experiment 1, eight healthy men performed unilateral elbow flexion exercise to failure at 30% of one-repetition maximum with BFR (at 40% of estimated arterial occlusion pressure) and free blood flow (FBF). During the exercise, muscle activity and tissue oxygenation were measured from the biceps brachii. In experiment 2, another eight healthy men completed 6 weeks of elbow flexion training with BFR and FBF. The number of repetitions to failure at submaximal load (R
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1016295-1
    ISSN 1469-445X ; 0958-0670
    ISSN (online) 1469-445X
    ISSN 0958-0670
    DOI 10.1113/EP091310
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    Uc I Zs.102: Show issues Location:
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  8. Article ; Online: Where is the perfect triangle in the liver allocation system?

    Sasaki, Kazunari / Melcher, Marc L

    The lancet. Healthy longevity

    2024  Volume 5, Issue 5, Page(s) e310–e311

    MeSH term(s) Humans ; Liver Transplantation ; Tissue and Organ Procurement
    Language English
    Publishing date 2024-05-03
    Publishing country England
    Document type Journal Article
    ISSN 2666-7568
    ISSN (online) 2666-7568
    DOI 10.1016/S2666-7568(24)00064-3
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  9. Article ; Online: Sensory and physicochemical characteristics of Japanese jidori chicken (Choshu-Kurokashiwa) and broiler thigh meat: Effect of cooking procedure.

    Murata, Shohei / Sasaki, Keisuke

    Animal science journal = Nihon chikusan Gakkaiho

    2024  Volume 95, Issue 1, Page(s) e13932

    Abstract: This study aimed to investigate the effects of various cooking procedures on the sensory and physicochemical properties of Japanese jidori chicken (Choshu-Kurokashiwa) and broiler thigh meat. Thigh meats were cooked using three different procedures: ... ...

    Abstract This study aimed to investigate the effects of various cooking procedures on the sensory and physicochemical properties of Japanese jidori chicken (Choshu-Kurokashiwa) and broiler thigh meat. Thigh meats were cooked using three different procedures: grilling, boiling, and deep-frying. Subsequently, we performed sensory evaluation by a trained panel and instrumental analysis on both raw and cooked meat to determine changes in pH, shear force value, cooking loss, nucleotide metabolite contents, and proximate, free amino acid, and fatty acid composition. From the sensory evaluation, "springiness" and "chewiness" were found to be characteristics of Choshu-Kurokashiwa thigh meat among all cooking procedures. In terms of "juiciness" and "sulfur flavor," chicken breed and cooking procedure interacted, and these were considerably higher in Choshu-Kurokashiwa meat than in broiler meat only when boiling. In the instrumental analysis, Choshu-Kurokashiwa meat showed a considerably higher shear force value and lower free amino acid content than broiler meat, regardless of the cooking procedure used. Again, in terms of cooking loss, chicken breed and cooking procedure interacted, and this was considerably lower in Choshu-Kurokashiwa meat than in broiler meat only when boiling. These results showed that cooking procedure should be considered when describing the sensory characteristics of jidori thigh meat.
    MeSH term(s) Animals ; Chickens ; Thigh ; Japan ; Cooking ; Meat/analysis ; Amino Acids
    Chemical Substances Amino Acids
    Language English
    Publishing date 2024-02-23
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2095161-9
    ISSN 1740-0929 ; 1344-3941
    ISSN (online) 1740-0929
    ISSN 1344-3941
    DOI 10.1111/asj.13932
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  10. Article: [Standard Precaution during COVID-19 Pandemic].

    Sasaki, Kota

    Nihon Hoshasen Gijutsu Gakkai zasshi

    2021  Volume 77, Issue 1, Page(s) 94–98

    MeSH term(s) COVID-19/prevention & control ; Humans ; Pandemics/prevention & control ; Reference Standards ; SARS-CoV-2
    Language Japanese
    Publishing date 2021-01-19
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2269092-X
    ISSN 1881-4883 ; 0369-4305
    ISSN (online) 1881-4883
    ISSN 0369-4305
    DOI 10.6009/jjrt.2021_JSRT_77.1.94
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