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Article: Robotic wedge resection of a rare gastric perivascular epithelioid cell tumor: A case report.

Marano, Alessandra / Maione, Francesca / Woo, Yanghee / Pellegrino, Luca / Geretto, Paolo / Sasia, Diego / Fortunato, Mirella / Orcioni, Giulio Fraternali / Priotto, Roberto / Fasoli, Renato / Borghi, Felice

World journal of clinical cases

2019 Volume 7, Issue 23, Page(s) 4011–4019

Abstract: Background: Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal neoplasm that can arise in many different organs with a broad spectrum of biological behavior, from indolent to aggressive progression. Only ten cases of gastric PEComas have ...

Abstract	Background: Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal neoplasm that can arise in many different organs with a broad spectrum of biological behavior, from indolent to aggressive progression. Only ten cases of gastric PEComas have been reported in the English literature, which were treated with endoscopic, laparoscopic, or open resections. Due to its rarity, the optimal surgical management and prognosis of this tumor are still uncertain. Case summary: We present a case of robotic wedge resection of a 6.5 cm bleeding lesion of the gastric fundus located 3 cm below the esophago-gastric junction in a 55-year-old man. Biopsy revealed a malignant tumor with epithelioid cells focally positive for muscle markers desmin and smooth muscle actin. In addition, histology revealed that the tumor was positive for HMB-45, melan-A (MART-1), microphthalmia transcription factor and negative for pan-cytokeratin AE1/AE3, CD34, p40, DOG-1, CD117 (c-kit), S100, CD3, CD79a, caldesmon and myogenin. These markers suggested the possibility of a PEComa. The patient underwent a diagnostic laparoscopy Conclusion: Gastric PEComa can be treated with a robotic R0 resection with acceptable postoperative and short-term oncological outcomes.
Language	English
Publishing date	2019-11-30
Publishing country	United States
Document type	Case Reports
ISSN	2307-8960
ISSN	2307-8960
DOI	10.12998/wjcc.v7.i23.4011
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Article ; Online: Subgingival Microbiota in White Patients With Desquamative Gingivitis: A Cross-Sectional Study.

Arduino, Paolo G / Romano, Federica / Sasia, Danilo / Broccoletti, Roberto / Ricceri, Fulvio / Barbui, Anna Maria / Brossa, Silvia / Cipriani, Raffaella / Cricenti, Luca / Cabras, Marco / Aimetti, Mario

Journal of periodontology

2017 Volume 88, Issue 7, Page(s) 643–650

Abstract: Background: Presence of epithelial desquamation, erythema, and erosions on gingival tissue is usually described in the literature as desquamative gingivitis (DG). A wide range of autoimmune/dermatologic disorders can manifest as DG, although the two ... ...

Abstract	Background: Presence of epithelial desquamation, erythema, and erosions on gingival tissue is usually described in the literature as desquamative gingivitis (DG). A wide range of autoimmune/dermatologic disorders can manifest as DG, although the two more common are oral lichen planus and mucous membrane pemphigoid. The aim of this study is to investigate prevalence of 11 periodontopathogenic microorganisms in patients with DG and to compare it with the microbiologic status of individuals affected by plaque-induced gingivitis (pGI). Methods: Cross-sectional clinical and microbiologic data were obtained from 66 patients (33 in each group). Subgingival plaque samples were analyzed using semiquantitative polymerase chain reaction analysis. Results: Statistically significant difference, but with little clinical significance, was observed in gingival conditions between the two groups, probably due to the worse home control hygiene of patients with DG. Prevalence and levels of Aggregatibacter actinomycetemcomitans, Eikenella corrodens, and Fusobacterium nucleatum/periodonticum were statistically higher in samples from patients with DG than in those with pGI. In multivariate regression models, subgingival colonization of A. actinomycetemcomitans and F. nucleatum/periodonticum was not statistically associated with DG, whereas, high levels of E. corrodens were associated with 13-fold increased odds for DG. Conclusions: Microbiologic differences were found in subgingival plaque for patients with DG and pGI. This may suggest possible association between periodontal pathogens and DG.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Bacteria/isolation & purification ; Case-Control Studies ; Cross-Sectional Studies ; European Continental Ancestry Group ; Female ; Gingiva/microbiology ; Gingivitis/microbiology ; Humans ; Male ; Microbiota ; Middle Aged ; Odds Ratio ; Polymerase Chain Reaction ; Regression Analysis
Language	English
Publishing date	2017-03-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	390921-9
ISSN	1943-3670 ; 0022-3492 ; 1049-8885 ; 0095-960X
ISSN (online)	1943-3670
ISSN	0022-3492 ; 1049-8885 ; 0095-960X
DOI	10.1902/jop.2017.160745
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Article ; Online: Anastomosis configuration and technique following ileocaecal resection for Crohn's disease: a multicentre study.

Celentano, Valerio / Pellino, Gianluca / Spinelli, Antonino / Selvaggi, Francesco / Rottoli, Matteo / Poggioli, Gilberto / Sica, Giuseppe / Giglio, Mariano Cesare / Campanelli, Michela / Coco, Claudio / Rizzo, Gianluca / Sionne, Francesco / Colombo, Francesco / Sampietro, Gianluca / Lamperti, Giulia / Foschi, Diego / Ficari, Ferdinando / Vacca, Ludovica / Cricchio, Marta /

Giudici, Francesco / Selvaggi, Lucio / Sciaudone, Guido / Peltrini, Roberto / Manfreda, Andrea / Bucci, Luigi / Galleano, Raffaele / Ghazouani, Omar / Zorcolo, Luigi / Deidda, Simona / Restivo, Angelo / Braini, Andrea / Di Candido, Francesca / Sacchi, Matteo / Carvello, Michele / Martorana, Stefania / Bordignon, Giovanni / Angriman, Imerio / Variola, Angela / Di Ruscio, Mirko / Barugola, Giuliano / Geccherle, Andrea / Tropeano, Francesca Paola / Luglio, Gaetano / Tanzanu, Marta / Sasia, Diego / Migliore, Marco / Giuffrida, Maria Carmela / Marrano, Enrico / Moretto, Gianluigi / Impellizzeri, Harmony / Gallo, Gaetano / Vescio, Giuseppina / Sammarco, Giuseppe / Terrosu, Giovanni / Calini, Giacomo / Bondurri, Andrea / Maffioli, Anna / Zaffaroni, Gloria / Resegotti, Andrea / Mistrangelo, Massimiliano / Allaix, Marco Ettore / Botti, Fiorenzo / Prati, Matteo / Boni, Luigi / Perotti, Serena / Mineccia, Michela / Giuliani, Antonio / Romano, Lucia / Graziano, Giorgio Maria Paolo / Pugliese, Luigi / Pietrabissa, Andrea / Delaini, GianGaetano

Updates in surgery

2021 Volume 73, Issue 1, Page(s) 149–156

Abstract: A limited ileocaecal resection is the most frequently performed procedure for ileocaecal CD and different anastomotic configurations and techniques have been described. This manuscript audited the different anastomotic techniques used in a national study ...

Abstract	A limited ileocaecal resection is the most frequently performed procedure for ileocaecal CD and different anastomotic configurations and techniques have been described. This manuscript audited the different anastomotic techniques used in a national study and evaluated their influence on postoperative outcomes following ileocaecal resection for primary CD. This is a retrospective, multicentre, observational study promoted by the Italian Society of Colorectal Surgery (SICCR), including all adults undergoing elective ileocaecal resection for primary CD from June 2018 May 2019. Postoperative morbidity within 30 days of surgery was the primary endpoint. Postoperative length of hospital stay (LOS) and anastomotic leak rate were the secondary outcomes. 427 patients were included. The side to side anastomosis was the chosen configuration in 380 patients (89%). The stapled anastomotic (n = 286; 67%), techniques were preferred to hand-sewn (n = 141; 33%). Postoperative morbidity was 20.3% and anastomotic leak 3.7%. Anastomotic leak was independent of the type of anastomosis performed, while was associated with an ASA grade ≥ 3, presence of perianal disease and ileocolonic localization of disease. Four predictors of LOS were identified after multivariate analysis. The laparoscopic approach was the only associated with a reduced LOS (p = 0.017), while age, ASA grade ≥ 3 or administration of preoperative TPN were associated with increased LOS. The side to side was the most commonly used anastomotic configuration for ileocolic reconstruction following primary CD resection. There was no difference in postoperative morbidity according to anastomotic technique and configuration. Anastomotic leak was associated with ASA grade ≥ 3, a penetrating phenotype of disease and ileo-colonic distribution of CD.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anastomosis, Surgical/adverse effects ; Anastomosis, Surgical/methods ; Anastomotic Leak/epidemiology ; Anastomotic Leak/etiology ; Cecum/surgery ; Crohn Disease/surgery ; Digestive System Surgical Procedures/adverse effects ; Digestive System Surgical Procedures/methods ; Elective Surgical Procedures/methods ; Female ; Humans ; Ileum/surgery ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Reconstructive Surgical Procedures/methods ; Retrospective Studies ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2021-01-06
Publishing country	Italy
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	2572692-4
ISSN	2038-3312 ; 2038-131X
ISSN (online)	2038-3312
ISSN	2038-131X
DOI	10.1007/s13304-020-00918-z
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Article ; Online: Correction to: Surgical treatment of colonic Crohn's disease: a national snapshot study.

Celentano, Valerio / Pellino, Gianluca / Rottoli, Matteo / Poggioli, Gilberto / Sica, Giuseppe / Giglio, Mariano Cesare / Campanelli, Michela / Coco, Claudio / Rizzo, Gianluca / Sionne, Francesco / Colombo, Francesco / Sampietro, Gianluca / Lamperti, Giulia / Foschi, Diego / Ficari, Ferdinando / Vacca, Ludovica / Cricchio, Marta / Giudici, Francesco / Selvaggi, Lucio /

Sciaudone, Guido / Peltrini, Roberto / Manfreda, Andrea / Bucci, Luigi / Galleano, Raffaele / Ghazouani, Omar / Zorcolo, Luigi / Deidda, Simona / Restivo, Angelo / Braini, Andrea / Di Candido, Francesca / Sacchi, Matteo / Carvello, Michele / Martorana, Stefania / Bordignon, Giovanni / Angriman, Imerio / Variola, Angela / Barugola, Giuliano / Di Ruscio, Mirko / Tanzanu, Marta / Geccherle, Andrea / Tropeano, Francesca Paola / Luglio, Gaetano / Sasia, Diego / Migliore, Marco / Giuffrida, Maria Carmela / Marrano, Enrico / Moretto, Gianluigi / Impellizzeri, Harmony / Gallo, Gaetano / Vescio, Giuseppina / Sammarco, Giuseppe / Terrosu, Giovanni / Calini, Giacomo / Bondurri, Andrea / Maffioli, Anna / Zaffaroni, Gloria / Resegotti, Andrea / Mistrangelo, Massimiliano / Allaix, Marco Ettore / Botti, Fiorenzo / Prati, Matteo / Boni, Luigi / Perotti, Serena / Mineccia, Michela / Giuliani, Antonio / Romano, Lucia / Graziano, Giorgio Maria Paolo / Pugliese, Luigi / Pietrabissa, Andrea / Delaini, GianGaetano / Spinelli, Antonino / Selvaggi, Francesco

Langenbeck's archives of surgery

2021 Volume 407, Issue 8, Page(s) 3921–3924

Language	English
Publishing date	2021-09-29
Publishing country	Germany
Document type	Published Erratum
ZDB-ID	1423681-3
ISSN	1435-2451 ; 1435-2443
ISSN (online)	1435-2451
ISSN	1435-2443
DOI	10.1007/s00423-021-02119-7
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Article ; Online: It is time to define an organizational model for the prevention and management of infections along the surgical pathway: a worldwide cross-sectional survey.

Sartelli, Massimo / Labricciosa, Francesco M / Coccolini, Federico / Coimbra, Raul / Abu-Zidan, Fikri M / Ansaloni, Luca / Al-Hasan, Majdi N / Ansari, Shamshul / Barie, Philip S / Caínzos, Miguel Angel / Ceresoli, Marco / Chiarugi, Massimo / Claridge, Jeffrey A / Cicuttin, Enrico / Dellinger, Evan Patchen / Fry, Donald E / Guirao, Xavier / Hardcastle, Timothy Craig / Hecker, Andreas /

Leppäniemi, Ari K / Litvin, Andrey / Marwah, Sanjay / Maseda, Emilio / Mazuski, John E / Memish, Ziad Ahmed / Kirkpatrick, Andrew W / Pagani, Leonardo / Podda, Mauro / Rasa, Huseyin Kemal / Sakakushev, Boris E / Sawyer, Robert G / Tumietto, Fabio / Xiao, Yonghong / Aboubreeg, Wedad Faraj / Adamou, Harissou / Akhmeteli, Lali / Akin, Emrah / Alberio, Maria Grazia / Alconchel, Felipe / Magagi, Ibrahim Amadou / Araúz, Ana Belén / Argenio, Giulio / Atanasov, Boyko C / Atici, Semra Demirli / Awad, Selmy Sabry / Baili, Efstratia / Bains, Lovenish / Bala, Miklosh / Baraket, Oussama / Baral, Suman / Belskii, Vladislav A / Benboubker, Moussa / Ben-Ishay, Offir / Bordoni, Pierpaolo / Boumédiène, Abdalia / Brisinda, Giuseppe / Cavazzuti, Laura / Chandy, Sujith J / Chiarello, Maria Michela / Cillara, Nicola / Clarizia, Guglielmo / Cocuz, Maria-Elena / Cocuz, Iuliu Gabriel / Conti, Luigi / Coppola, Raffaella / Cui, Yunfeng / Czepiel, Jacek / D'Acapito, Fabrizio / Damaskos, Dimitrios / Das, Koray / De Simone, Belinda / Delibegovic, Samir / Demetrashvili, Zaza / Detanac, Dzemail S / Dhingra, Sameer / Di Bella, Stefano / Dimitrov, Evgeni N / Dogjani, Agron / D'Oria, Mario / Dumitru, Irina Magdalena / Elmangory, Mutasim M / Enciu, Octavian / Fantoni, Massimo / Filipescu, Daniela / Fleres, Francesco / Foghetti, Domitilla / Fransvea, Pietro / Gachabayov, Mahir / Galeiras, Rita / Gattuso, Gianni / Ghannam, Wagih M / Ghisetti, Valeria / Giraudo, Giorgio / Gonfa, Kebebe Bekele / Gonullu, Emre / Hamad, Yousif Tag Elsir Y / Hecker, Matthias / Isik, Arda / Ismail, Nizar / Ismail, Azzain / Jain, Sumita Agarwal / Kanj, Souha S / Kapoor, Garima / Karaiskos, Ilias / Kavalakat, Alfie J / Kenig, Jakub / Khamis, Faryal / Khokha, Vladimir / Kiguba, Ronald / Kim, Jae Il / Kobe, Yoshiro / Kok, Kenneth Yuh Yen / Kovacevic, Bojan M / Kryvoruchko, Igor Andreevich / Kuriyama, Akira / Landaluce-Olavarria, Aitor / Lasithiotakis, Konstantinos / Lohsiriwat, Varut / Lostoridis, Eftychios / Luppi, Davide / Vega, Gustavo Miguel Machain / Maegele, Marc / Marinis, Athanasios / Martines, Gennaro / Martínez-Pérez, Aleix / Massalou, Damien / Mesina, Cristian / Metan, Gökhan / Miranda-Novales, María Guadalupe / Mishra, Shyam Kumar / Mohamed, Mohaned Ibrahim Hussein / Mohamedahmed, Ali Yasen Y / Mora-Guzmán, Ismael / Mulita, Francesk / Musina, Ana-Maria / Navsaria, Pradeep H / Negoi, Ionut / Nita, Gabriela Elisa / O'Connor, Donal B / Ordoñez, Carlos Alberto / Pantalone, Desiré / Panyko, Arpád / Papadopoulos, Aristeidis / Pararas, Nikolaos / Pata, Francesco / Patel, Tapan / Pellino, Gianluca / Perra, Teresa / Perrone, Gennaro / Pesce, Antonio / Pintar, Tadeja / Popivanov, Georgi Ivanov / Porcu, Alberto / Quiodettis, Martha Alexa / Rahim, Razrim / Mitul, Ashrarur Rahman / Reichert, Martin / Rems, Miran / Campbell, Glendee Yolande Reynolds / Rocha-Pereira, Nuno / Rodrigues, Gabriel / Villamil, Gustavo Eduardo Roncancio / Rossi, Stefano / Sall, Ibrahima / Kafil, Hossein Samadi / Sasia, Diego / Seni, Jeremiah / Seretis, Charalampos / Serradilla-Martín, Mario / Shelat, Vishal G / Siribumrungwong, Boonying / Slavchev, Mihail / Solaini, Leonardo / Tan, Boun Kim / Tarasconi, Antonio / Tartaglia, Dario / Toma, Elena Adelina / Tomadze, Gia / Toro, Adriana / Tovani-Palone, Marcos Roberto / van Goor, Harry / Vasilescu, Alin / Vereczkei, Andras / Veroux, Massimiliano / Weckmann, Sergio Alberto / Widmer, Lukas Werner / Yahya, AliIbrahim / Zachariah, Sanoop K / Zakaria, Andee Dzulkarnaen / Zubareva, Nadezhda / Zuidema, Wietse P / Di Carlo, Isidoro / Cortese, Francesco / Baiocchi, Gian Luca / Maier, Ronald V / Catena, Fausto

World journal of emergency surgery : WJES

2022 Volume 17, Issue 1, Page(s) 17

Abstract: Background: The objectives of the study were to investigate the organizational characteristics of acute care facilities worldwide in preventing and managing infections in surgery; assess participants' perception regarding infection prevention and ... ...

Abstract	Background: The objectives of the study were to investigate the organizational characteristics of acute care facilities worldwide in preventing and managing infections in surgery; assess participants' perception regarding infection prevention and control (IPC) measures, antibiotic prescribing practices, and source control; describe awareness about the global burden of antimicrobial resistance (AMR) and IPC measures; and determine the role of the Coronavirus Disease 2019 pandemic on said awareness. Methods: A cross-sectional web-based survey was conducted contacting 1432 health care workers (HCWs) belonging to a mailing list provided by the Global Alliance for Infections in Surgery. The self-administered questionnaire was developed by a multidisciplinary team. The survey was open from May 22, 2021, and June 22, 2021. Three reminders were sent, after 7, 14, and 21 days. Results: Three hundred four respondents from 72 countries returned a questionnaire, with an overall response rate of 21.2%. Respectively, 90.4% and 68.8% of participants stated their hospital had a multidisciplinary IPC team or a multidisciplinary antimicrobial stewardship team. Local protocols for antimicrobial therapy of surgical infections and protocols for surgical antibiotic prophylaxis were present in 76.6% and 90.8% of hospitals, respectively. In 23.4% and 24.0% of hospitals no surveillance systems for surgical site infections and no monitoring systems of used antimicrobials were implemented. Patient and family involvement in IPC management was considered to be slightly or not important in their hospital by the majority of respondents (65.1%). Awareness of the global burden of AMR among HCWs was considered very important or important by 54.6% of participants. The COVID-19 pandemic was considered by 80.3% of respondents as a very important or important factor in raising HCWs awareness of the IPC programs in their hospital. Based on the survey results, the authors developed 15 statements for several questions regarding the prevention and management of infections in surgery. The statements may be the starting point for designing future evidence-based recommendations. Conclusion: Adequacy of prevention and management of infections in acute care facilities depends on HCWs behaviours and on the organizational characteristics of acute health care facilities to support best practices and promote behavioural change. Patient involvement in the implementation of IPC is still little considered. A debate on how operationalising a fundamental change to IPC, from being solely the HCWs responsibility to one that involves a collaborative relationship between HCWs and patients, should be opened.
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents ; COVID-19 ; Cross-Sectional Studies ; Humans ; Models, Organizational ; Pandemics/prevention & control
Chemical Substances	Anti-Bacterial Agents ; Anti-Infective Agents
Language	English
Publishing date	2022-03-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2233734-9
ISSN	1749-7922 ; 1749-7922
ISSN (online)	1749-7922
ISSN	1749-7922
DOI	10.1186/s13017-022-00420-4
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Article ; Online: Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago.

Perrone, Gennaro / Giuffrida, Mario / Abu-Zidan, Fikri / Kruger, Vitor F / Livrini, Marco / Petracca, Gabriele Luciano / Rossi, Giorgio / Tarasconi, Antonio / Tian, Brian W C A / Bonati, Elena / Mentz, Ricardo / Mazzini, Federico N / Campana, Juan P / Gasser, Elisabeth / Kafka-Ritsch, Reinhold / Felsenreich, Daniel M / Dawoud, Christopher / Riss, Stefan / Gomes, Carlos Augusto /

Gomes, Felipe Couto / Gonzaga, Ricardo Alessandro Teixeira / Canton, Cassio Alfred Brattig / Pereira, Bruno Monteiro / Fraga, Gustavo P / Zem, Leticia Gonçalves / Cordeiro-Fonseca, Vinicius / de Mesquita Tauil, Renato / Atanasov, Boyko / Belev, Nikolay / Kovachev, Nikola / Meléndez, L Juan José / Dimova, Ana / Dimov, Stefan / Zelić, Zdravko / Augustin, Goran / Bogdanić, Branko / Morić, Trpimir / Chouillard, Elie / Bajul, Melinda / De Simone, Belinda / Panis, Yves / Esposito, Francesco / Notarnicola, Margherita / Lauka, Lelde / Fabbri, Anna / Hentati, Hassen / Fnaiech, Iskander / Aurélien, Venara / Bougard, Marie / Roulet, Maxime / Demetrashvili, Zaza / Pipia, Irakli / Merabishvili, Giorgi / Bouliaris, Konstantinos / Koukoulis, Georgios / Doudakmanis, Christos / Xenaki, Sofia / Chrysos, Emmanuel / Kokkinakis, Stamatios / Vassiliu, Panteleimon / Michalopoulos, Nikolaos / Margaris, Ioannis / Kechagias, Aristotelis / Avgerinos, Konstantinos / Katunin, Jevgeni / Lostoridis, Eftychios / Nagorni, Eleni-Aikaterini / Pujante, Antonio / Mulita, Francesk / Maroulis, Ioannis / Vailas, Michail / Marinis, Athanasios / Siannis, Ioannis / Bourbouteli, Eirini / Manatakis, Dimitrios K / Tasis, Nikolaos / Acheimastos, Vasileios / Maria, Sotiropoulou / Stylianos, Kapiris / Kuzeridis, Harilaos / Korkolis, Dimitrios / Fradelos, Evangelos / Kavalieratos, George / Petropoulou, Thalia / Polydorou, Andreas / Papacostantinou, Ioannis / Triantafyllou, Tania / Kimpizi, Despina / Theodorou, Dimitrios / Toutouzas, Konstantinos / Chamzin, Alexandros / Frountzas, Maximos / Schizas, Dimitrios / Karavokyros, Ioannis / Syllaios, Athanasios / Charalabopoulos, Alexandros / Boura, Maria / Baili, Efstratia / Ioannidis, Orestis / Loutzidou, Lydia / Anestiadou, Elissavet / Tsouknidas, Ioannis / Petrakis, Georgios / Polenta, Eleni / Bains, Lovenish / Gupta, Rahul / Singh, Sudhir K / Khanduri, Archana / Bala, Miklosh / Kedar, Asaf / Pisano, Marcello / Podda, Mauro / Pisanu, Adolfo / Martines, Gennaro / Trigiante, Giuseppe / Lantone, Giuliano / Agrusa, Antonino / Di Buono, Giuseppe / Buscemi, Salvatore / Veroux, Massimiliano / Gioco, Rossella / Veroux, Gastone / Oragano, Luigi / Zonta, Sandro / Lovisetto, Federico / Feo, Carlo V / Pesce, Antonio / Fabbri, Nicolò / Lantone, Giulio / Marino, Fabio / Perrone, Fabrizio / Vincenti, Leonardo / Papagni, Vincenzo / Picciariello, Arcangelo / Rossi, Stefano / Picardi, Biagio / Del Monte, Simone Rossi / Visconti, Diego / Osella, Giulia / Petruzzelli, Luca / Pignata, Giusto / Andreuccetti, Jacopo / D'Alessio, Rossella / Buonfantino, Massimo / Guaitoli, Eleonora / Spinelli, Stefano / Sampietro, Gianluca Matteo / Corbellini, Carlo / Lorusso, Leonardo / Frontali, Alice / Pezzoli, Isabella / Bonomi, Alessandro / Chierici, Andrea / Cotsoglou, Christian / Manca, Giuseppe / Delvecchio, Antonella / Musa, Nicola / Casati, Massimiliano / Letizia, Laface / Abate, Emmanuele / Ercolani, Giorgio / D'Acapito, Fabrizio / Solaini, Leonardo / Guercioni, Gianluca / Cicconi, Simone / Sasia, Diego / Borghi, Felice / Giraudo, Giorgio / Sena, Giuseppe / Castaldo, Pasquale / Cardamone, Eugenia / Portale, Giuseppe / Zuin, Matteo / Spolverato, Ylenia / Esposito, Marialusia / Isernia, Roberta Maria / Di Salvo, Maria / Manunza, Romina / Esposito, Giuseppe / Agus, Marcello / Asti, Emanuele Luigi Giuseppe / Bernardi, Daniele Tiziano / Tonucci, Tommaso Panici / Luppi, Davide / Casadei, Massimiliano / Bonilauri, Stefano / Pezzolla, Angela / Panebianco, Annunziata / Laforgia, Rita / De Luca, Maurizio / Zese, Monica / Parini, Dario / Jovine, Elio / De Sario, Giuseppina / Lombardi, Raffaele / Aprea, Giovanni / Palomba, Giuseppe / Capuano, Marianna / Argenio, Giulio / Orio, Gianluca / Armellino, Mariano Fortunato / Troian, Marina / Guerra, Martina / Nagliati, Carlo / Biloslavo, Alan / Germani, Paola / Aizza, Giada / Monsellato, Igor / Chahrour, Ali Chaouki / Anania, Gabriele / Bombardini, Cristina / Bagolini, Francesco / Sganga, Gabriele / Fransvea, Pietro / Bianchi, Valentina / Boati, Paolo / Ferrara, Francesco / Palmieri, Francesco / Cianci, Pasquale / Gattulli, Domenico / Restini, Enrico / Cillara, Nicola / Cannavera, Alessandro / Nita, Gabriela Elisa / Sarnari, Jlenia / Roscio, Francesco / Clerici, Federico / Scandroglio, Ildo / Berti, Stefano / Cadeo, Alessandro / Filippelli, Alice / Conti, Luigi / Grassi, Carmine / Cattaneo, Gaetano Maria / Pighin, Marina / Papis, Davide / Gambino, Giovanni / Bertino, Vanessa / Schifano, Domenico / Prando, Daniela / Fogato, Luisella / Cavallo, Fabio / Ansaloni, Luca / Picheo, Roberto / Pontarolo, Nicholas / Depalma, Norma / Spampinato, Marcello / D'Ugo, Stefano / Lepre, Luca / Capponi, Michela Giulii / Campa, Rossella Domenica / Sarro, Giuliano / Dinuzzi, Vincenza Paola / Olmi, Stefano / Uccelli, Matteo / Ferrari, Davide / Inama, Marco / Moretto, Gianluigi / Fontana, Michele / Favi, Francesco / Picariello, Erika / Rampini, Alessia / Barberis, Andrea / Azzinnaro, Antonio / Oliva, Alba / Totaro, Luigi / Benzoni, Ilaria / Ranieri, Valerio / Capolupo, Gabriella Teresa / Carannante, Filippo / Caricato, Marco / Ronconi, Maurizio / Casiraghi, Silvia / Casole, Giovanni / Pantalone, Desire / Alemanno, Giovanni / Scheiterle, Maximilian / Ceresoli, Marco / Cereda, Marco / Fumagalli, Chiara / Zanzi, Federico / Bolzon, Stefano / Guerra, Enrico / Lecchi, Francesca / Cellerino, Paola / Ardito, Antonella / Scaramuzzo, Rosa / Balla, Andrea / Lepiane, Pasquale / Tartaglia, Nicola / Ambrosi, Antonio / Pavone, Giovanna / Palini, Gian Marco / Veneroni, Simone / Garulli, Gianluca / Ricci, Claudio / Torre, Beatrice / Russo, Iris Shari / Rottoli, Matteo / Tanzanu, Marta / Belvedere, Angela / Milone, Marco / Manigrasso, Michele / De Palma, Giovanni Domenico / Piccoli, Micaela / Pattacini, Gianmaria Casoni / Magnone, Stefano / Bertoli, Paolo / Pisano, Michele / Massucco, Paolo / Palisi, Marco / Luzzi, Andrea-Pierre / Fleres, Francesco / Clarizia, Guglielmo / Spolini, Alessandro / Kobe, Yoshiro / Toma, Takayuki / Shimamura, Fumihiko / Parker, Robert / Ranketi, Sinkeet / Mitei, Mercy / Svagzdys, Saulius / Pauzas, Henrikas / Zilinskas, Justas / Poskus, Tomas / Kryzauskas, Marius / Jakubauskas, Matas / Zakaria, Andee Dzulkarnaen / Zakaria, Zaidi / Wong, Michael Pak-Kai / Jusoh, Asri Che / Zakaria, Muhammad Nazreen / Cruz, Daniel Rios / Elizalde, Aurea Barbara Rodriguez / Reynaud, Alejandro Bañon / Hernandez, Edgard Efren Lozada / Monroy, Jose Maria Victor Palomo / Hinojosa-Ugarte, Diego / Quiodettis, Martha / Du Bois, María Esther / Latorraca, José / Major, Piotr / Pędziwiatr, Michał / Pisarska-Adamczyk, Magdalena / Walędziak, Maciej / Kwiatkowski, Andrzej / Czyżykowski, Łukasz / da Costa, Silvia Dantas / Pereira, Bela / Ferreira, Ana Rita Oliveira / Almeida, Filipe / Rocha, Ricardo / Carneiro, Carla / Perez, Diego Pita / Carvas, João / Rocha, Catarina / Ferreira, Cátia / Marques, Rita / Fernandes, Urânia / Leao, Pedro / Goulart, André / Pereira, Rita Gonçalves / Patrocínio, Sara Daniela Direito / de Mendonça, Nuno Gonçalo Gonçalves / Manso, Maria Isabel Cerqueira / Morais, Henrique Manuel Cardoso / Cardoso, Paulo Sebastião / Calu, Valentin / Miron, Adrian / Toma, Elena Adelina / Gachabayov, Mahir / Abdullaev, Abakar / Litvin, Andrey / Nechay, Taras / Tyagunov, Alexander / Yuldashev, Anvar / Bradley, Alison / Wilson, Michael / Panyko, Arpád / Látečková, Zuzana / Lacko, Vladimír / Lesko, Dusan / Soltes, Marek / Radonak, Jozef / Turrado-Rodriguez, Victor / Termes-Serra, Roser / Morales-Sevillano, Xavier / Lapolla, Pierfrancesco / Mingoli, Andrea / Brachini, Gioia / Degiuli, Maurizio / Sofia, Silvia / Reddavid, Rossella / de Manzoni Garberini, Andrea / Buffone, Angelica / Del Pozo, Eduardo Perea / Aparicio-Sánchez, Daniel / Dos Barbeito, Sandra / Estaire-Gómez, Mercedes / Vitón-Herrero, Rebeca / de Los Ángeles Gil Olarte-Marquez, Mª / Gil-Martínez, José / Alconchel, Felipe / Nicolás-López, Tatiana / Rahy-Martin, Aida Cristina / Pelloni, María / Bañolas-Suarez, Raquel / Mendoza-Moreno, Fernando / Nisa, Francisca García-Moreno / Díez-Alonso, Manuel / Rodas, María Elisa Valle / Agundez, María Carmona / Andrés, María Inmaculada Pérez / Moreira, Claudia Cristina Lopes / Perez, Aintzane Lizarazu / Ponce, Iñigo Augusto / González-Castillo, Ana María / Membrilla-Fernández, Estela / Salvans, Silvia / Serradilla-Martín, Mario / Pardo, Pablo Sancho / Rivera-Alonso, Daniel / Dziakova, Jana / Huguet, Jose Mugüerza / Valle, Naila Pagès / Ruiz, Enrique Colás / Valcárcel, Cristina Rey / Moreno, Cristina Ruiz / Salazar, Yeniffer Tatiana Moreno / García, Juan Jesús Rubio / Micó, Silvia Sevila / López, Joaquín Ruiz / Farré, Silvia Pérez / Gomez, Maite Santamaria / Petit, Nuria Mestres / Titos-García, Alberto / Aranda-Narváez, Jose Manuel / Romacho-López, Laura / Sánchez-Guillén, Luis / Aranaz-Ostariz, Veronica / Bosch-Ramírez, Marina / Martínez-Pérez, Aleix / Martínez-López, Elías / Sebastián-Tomás, Juan Carlos / Jimenez-Riera, Granada / Jimenez-Vega, Javier / Cuellar, Jose Aurelio Navas / Campos-Serra, Andrea / Muñoz-Campaña, Anna / Gràcia-Roman, Raquel / Alegre, Javier Martínez / Pinto, Francisca Lima / O'Sullivan, Sara Nuñez / Antona, Francisco Blanco / Jiménez, Beatriz Muñoz / López-Sánchez, Jaime / Carmona, Zahira Gómez / Fernández, Rocio Torres / Sierra, Isabel Blesa / de León, Laura Román García / Moreno, Verónica Polaino / Iglesias, Eva / Cumplido, Paola Lora / Bravo, Altea Arango / Simó, Ignacio Rey / Domínguez, Carlota López / Caamaño, Aloia Guerreiro / Lozano, Rafael Calleja / Martínez, Manuel Durán / Torres, Álvaro Naranjo / de Quiros, Javier Tomas Morales Bernaldo / Pellino, Gianluca / Cloquell, Miriam Moratal / Moller, Elsa García / Jalal-Eldin, Sami / Abdoun, Ahmed K / Hamid, Hytham K S / Lohsiriwat, Varut / Mongkhonsupphawan, Aitsariya / Baraket, Oussama / Ayed, Karim / Abbassi, Imed / Ali, Ali Ben / Ammar, Houssem / Kchaou, Ali / Tlili, Ahmed / Zribi, Imen / Colak, Elif / Polat, Suleyman / Koylu, Zehra Alan / Guner, Ali / Usta, Mehmet Arif / Reis, Murat Emre / Mantoglu, Baris / Gonullu, Emre / Akin, Emrah / Altintoprak, Fatih / Bayhan, Zulfu / Firat, Necattin / Isik, Arda / Memis, Ufuk / Bayrak, Mehmet / Altıntaş, Yasemin / Kara, Yasin / Bozkurt, Mehmet Abdussamet / Kocataş, Ali / Das, Koray / Seker, Ahmet / Ozer, Nazmi / Atici, Semra Demirli / Tuncer, Korhan / Kaya, Tayfun / Ozkan, Zeynep / Ilhan, Onur / Agackiran, Ibrahim / Uzunoglu, Mustafa Yener / Demirbas, Eren / Altinel, Yuksel / Meric, Serhat / Hacım, Nadir Adnan / Uymaz, Derya Salim / Omarov, Nail / Balık, Emre / Tebala, Giovanni D / Khalil, Hany / Rana, Mridul / Khan, Mansoor / Florence, Charlotte / Swaminathan, Christie / Leo, Cosimo Alex / Liasis, Lampros / Watfah, Josef / Trostchansky, Ivan / Delgado, Edward / Pontillo, Marcelo / Latifi, Rifat / Coimbra, Raul / Edwards, Sara / Lopez, Ana / Velmahos, George / Dorken, Ander / Gebran, Anthony / Palmer, Amanda / Oury, Jeffrey / Bardes, James M / Seng, Sirivan Suon / Coffua, Lauren S / Ratnasekera, Asanthi / Egodage, Tanya / Echeverria-Rosario, Karla / Armento, Isabella / Napolitano, Lena M / Sangji, Naveen F / Hemmila, Mark / Quick, Jacob A / Austin, Tyler R / Hyman, Theodore S / Curtiss, William / McClure, Amanda / Cairl, Nicholas / Biffl, Walter L / Truong, Hung P / Schaffer, Kathryn / Reames, Summer / Banchini, Filippo / Capelli, Patrizio / Coccolini, Federico / Sartelli, Massimo / Bravi, Francesca / Vallicelli, Carlo / Agnoletti, Vanni / Baiocchi, Gian Luca / Catena, Fausto

World journal of emergency surgery : WJES

2024 Volume 19, Issue 1, Page(s) 14

Abstract: Background: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann's procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute ... ...

Abstract	Background: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann's procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA. Methods: This is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 patients with left-sided colonic emergencies who required surgery were included from 204 centers during the period of March 1, 2020, to May 31, 2020. with a 1-year follow-up. Results: 564 patients (43.1%) were females. The mean age was 65.9 ± 15.6 years. HP was performed in 697 (57.3%) patients and RPA in 384 (31.6%) cases. Complicated acute diverticulitis was the most common cause of left-sided colonic emergencies (40.2%), followed by colorectal malignancy (36.6%). Severe complications (Clavien-Dindo ≥ 3b) were higher in the HP group (P < 0.001). 30-day mortality was higher in HP patients (13.7%), especially in case of bowel perforation and diffused peritonitis. 1-year follow-up showed no differences on ostomy reversal rate between HP and RPA. (P = 0.127). A backward likelihood logistic regression model showed that RPA was preferred in younger patients, having low ASA score (≤ 3), in case of large bowel obstruction, absence of colonic ischemia, longer time from admission to surgery, operating early at the day working hours, by a surgeon who performed more than 50 colorectal resections. Conclusions: After 100 years since the first Hartmann's procedure, HP remains the most common treatment for left-sided colorectal emergencies. Treatment's choice depends on patient characteristics, the time of surgery and the experience of the surgeon. RPA should be considered as the gold standard for surgery, with HP being an exception.
MeSH term(s)	Female ; Humans ; Middle Aged ; Aged ; Aged, 80 and over ; Male ; Emergencies ; Prospective Studies ; Postoperative Complications/etiology ; Anastomosis, Surgical/methods ; Colorectal Neoplasms/surgery
Language	English
Publishing date	2024-04-16
Publishing country	England
Document type	Observational Study ; Multicenter Study ; Journal Article
ZDB-ID	2233734-9
ISSN	1749-7922 ; 1749-7922
ISSN (online)	1749-7922
ISSN	1749-7922
DOI	10.1186/s13017-024-00543-w
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Article ; Online: The ChoCO-W prospective observational global study: Does COVID-19 increase gangrenous cholecystitis?

De Simone, Belinda / Abu-Zidan, Fikri M / Chouillard, Elie / Di Saverio, Salomone / Sartelli, Massimo / Podda, Mauro / Gomes, Carlos Augusto / Moore, Ernest E / Moug, Susan J / Ansaloni, Luca / Kluger, Yoram / Coccolini, Federico / Landaluce-Olavarria, Aitor / Estraviz-Mateos, Begoña / Uriguen-Etxeberria, Ana / Giordano, Alessio / Luna, Alfonso Palmieri / Amín, Luz Adriana Hernández / Hernández, Adriana María Palmieri /

Shabana, Amanda / Dzulkarnaen, Zakaria Andee / Othman, Muhammad Asyraf / Sani, Mohamad Ikhwan / Balla, Andrea / Scaramuzzo, Rosa / Lepiane, Pasquale / Bottari, Andrea / Staderini, Fabio / Cianchi, Fabio / Cavallaro, Andrea / Zanghì, Antonio / Cappellani, Alessandro / Campagnacci, Roberto / Maurizi, Angela / Martinotti, Mario / Ruggieri, Annamaria / Jusoh, Asri Che / Rahman, Karim Abdul / Zulkifli, Anis Suraya M / Petronio, Barbara / Matías-García, Belén / Quiroga-Valcárcel, Ana / Mendoza-Moreno, Fernando / Atanasov, Boyko / Campanile, Fabio Cesare / Vecchioni, Ilaria / Cardinali, Luca / Travaglini, Grazia / Sebastiani, Elisa / Chooklin, Serge / Chuklin, Serhii / Cianci, Pasquale / Restini, Enrico / Capuzzolo, Sabino / Currò, Giuseppe / Filippo, Rosalinda / Rispoli, Michele / Aparicio-Sánchez, Daniel / Muñóz-Cruzado, Virginia Durán / Barbeito, Sandra Dios / Delibegovic, Samir / Kesetovic, Amar / Sasia, Diego / Borghi, Felice / Giraudo, Giorgio / Visconti, Diego / Doria, Emanuele / Santarelli, Mauro / Luppi, Davide / Bonilauri, Stefano / Grossi, Ugo / Zanus, Giacomo / Sartori, Alberto / Piatto, Giacomo / De Luca, Maurizio / Vita, Domenico / Conti, Luigi / Capelli, Patrizio / Cattaneo, Gaetano Maria / Marinis, Athanasios / Vederaki, Styliani-Aikaterini / Bayrak, Mehmet / Altıntas, Yasemin / Uzunoglu, Mustafa Yener / Demirbas, Iskender Eren / Altinel, Yuksel / Meric, Serhat / Aktimur, Yunus Emre / Uymaz, Derya Salim / Omarov, Nail / Azamat, Ibrahim / Lostoridis, Eftychios / Nagorni, Eleni-Aikaterini / Pujante, Antonio / Anania, Gabriele / Bombardini, Cristina / Bagolini, Francesco / Gonullu, Emre / Mantoglu, Baris / Capoglu, Recayi / Cappato, Stefano / Muzio, Elena / Colak, Elif / Polat, Suleyman / Koylu, Zehra Alan / Altintoprak, Fatih / Bayhan, Zülfü / Akin, Emrah / Andolfi, Enrico / Rezart, Sulce / Kim, Jae Il / Jung, Sung Won / Shin, Yong Chan / Enciu, Octavian / Toma, Elena Adelina / Medas, Fabio / Canu, Gian Luigi / Cappellacci, Federico / D'Acapito, Fabrizio / Ercolani, Giorgio / Solaini, Leonardo / Roscio, Francesco / Clerici, Federico / Gelmini, Roberta / Serra, Francesco / Rossi, Elena Giulia / Fleres, Francesco / Clarizia, Guglielmo / Spolini, Alessandro / Ferrara, Francesco / Nita, Gabriela / Sarnari, Jlenia / Gachabayov, Mahir / Abdullaev, Abakar / Poillucci, Gaetano / Palini, Gian Marco / Veneroni, Simone / Garulli, Gianluca / Piccoli, Micaela / Pattacini, Gianmaria Casoni / Pecchini, Francesca / Argenio, Giulio / Armellino, Mariano Fortunato / Brisinda, Giuseppe / Tedesco, Silvia / Fransvea, Pietro / Ietto, Giuseppe / Franchi, Caterina / Carcano, Giulio / Martines, Gennaro / Trigiante, Giuseppe / Negro, Giulia / Vega, Gustavo Machain / González, Agustín Rodríguez / Ojeda, Leonardo / Piccolo, Gaetano / Bondurri, Andrea / Maffioli, Anna / Guerci, Claudio / Sin, Boo Han / Zuhdi, Zamri / Azman, Azlanudin / Mousa, Hussam / Al Bahri, Shadi / Augustin, Goran / Romic, Ivan / Moric, Trpimir / Nikolopoulos, Ioannis / Andreuccetti, Jacopo / Pignata, Giusto / D'Alessio, Rossella / Kenig, Jakub / Skorus, Urszula / Fraga, Gustavo Pereira / Hirano, Elcio Shiyoiti / de Lima Bertuol, Jackson Vinícius / Isik, Arda / Kurnaz, Eray / Asghar, Mohammad Sohail / Afzal, Ameer / Akbar, Ali / Nikolouzakis, Taxiarchis Konstantinos / Lasithiotakis, Konstantinos / Chrysos, Emmanuel / Das, Koray / Özer, Nazmi / Seker, Ahmet / Ibrahim, Mohamed / Hamid, Hytham K S / Babiker, Ahmed / Bouliaris, Konstantinos / Koukoulis, George / Kolla, Chrysoula-Christina / Lucchi, Andrea / Agostinelli, Laura / Taddei, Antonio / Fortuna, Laura / Agostini, Carlotta / Licari, Leo / Viola, Simona / Callari, Cosimo / Laface, Letizia / Abate, Emmanuele / Casati, Massimiliano / Anastasi, Alessandro / Canonico, Giuseppe / Gabellini, Linda / Tosi, Lorenzo / Guariniello, Anna / Zanzi, Federico / Bains, Lovenish / Sydorchuk, Larysa / Iftoda, Oksana / Sydorchuk, Andrii / Malerba, Michele / Costanzo, Federico / Galleano, Raffaele / Monteleone, Michela / Costanzi, Andrea / Riva, Carlo / Walędziak, Maciej / Kwiatkowski, Andrzej / Czyżykowski, Łukasz / Major, Piotr / Strzałka, Marcin / Matyja, Maciej / Natkaniec, Michal / Valenti, Maria Rosaria / Di Vita, Maria Domenica Pia / Sotiropoulou, Maria / Kapiris, Stylianos / Massalou, Damien / Veroux, Massimiliano / Volpicelli, Alessio / Gioco, Rossella / Uccelli, Matteo / Bonaldi, Marta / Olmi, Stefano / Nardi, Matteo / Livadoti, Giada / Mesina, Cristian / Dumitrescu, Theodor Viorel / Ciorbagiu, Mihai Calin / Ammendola, Michele / Ammerata, Giorgio / Romano, Roberto / Slavchev, Mihail / Misiakos, Evangelos P / Pikoulis, Emmanouil / Papaconstantinou, Dimitrios / Elbahnasawy, Mohamed / Abdel-Elsalam, Sherief / Felsenreich, Daniel M / Jedamzik, Julia / Michalopoulos, Nikolaos V / Sidiropoulos, Theodoros A / Papadoliopoulou, Maria / Cillara, Nicola / Deserra, Antonello / Cannavera, Alessandro / Negoi, Ionuţ / Schizas, Dimitrios / Syllaios, Athanasios / Vagios, Ilias / Gourgiotis, Stavros / Dai, Nick / Gurung, Rekha / Norrey, Marcus / Pesce, Antonio / Feo, Carlo Vittorio / Fabbri, Nicolo' / Machairas, Nikolaos / Dorovinis, Panagiotis / Keramida, Myrto D / Mulita, Francesk / Verras, Georgios Ioannis / Vailas, Michail / Yalkin, Omer / Iflazoglu, Nidal / Yigit, Direnc / Baraket, Oussama / Ayed, Karim / Ghalloussi, Mohamed Hedi / Patias, Parmenion / Ntokos, Georgios / Rahim, Razrim / Bala, Miklosh / Kedar, Asaf / Sawyer, Robert G / Trinh, Anna / Miller, Kelsey / Sydorchuk, Ruslan / Knut, Ruslan / Plehutsa, Oleksandr / Liman, Rumeysa Kevser / Ozkan, Zeynep / Kader, Saleh Abdel / Gupta, Sanjay / Gureh, Monika / Saeidi, Sara / Aliakbarian, Mohsen / Dalili, Amin / Shoko, Tomohisa / Kojima, Mitsuaki / Nakamoto, Raira / Atici, Semra Demirli / Tuncer, Gizem Kilinc / Kaya, Tayfun / Delis, Spiros G / Rossi, Stefano / Picardi, Biagio / Del Monte, Simone Rossi / Triantafyllou, Tania / Theodorou, Dimitrios / Pintar, Tadeja / Salobir, Jure / Manatakis, Dimitrios K / Tasis, Nikolaos / Acheimastos, Vasileios / Ioannidis, Orestis / Loutzidou, Lydia / Symeonidis, Savvas / de Sá, Tiago Correia / Rocha, Mónica / Guagni, Tommaso / Pantalone, Desiré / Maltinti, Gherardo / Khokha, Vladimir / Abdel-Elsalam, Wafaa / Ghoneim, Basma / López-Ruiz, José Antonio / Kara, Yasin / Zainudin, Syaza / Hayati, Firdaus / Azizan, Nornazirah / Khei, Victoria Tan Phooi / Yi, Rebecca Choy Xin / Sellappan, Harivinthan / Demetrashvili, Zaza / Lekiashvili, Nika / Tvaladze, Ana / Froiio, Caterina / Bernardi, Daniele / Bonavina, Luigi / Gil-Olarte, Angeles / Grassia, Sebastiano / Romero-Vargas, Estela / Bianco, Francesco / Gumbs, Andrew A / Dogjani, Agron / Agresta, Ferdinando / Litvin, Andrey / Balogh, Zsolt J / Gendrikson, George / Martino, Costanza / Damaskos, Dimitrios / Pararas, Nikolaos / Kirkpatrick, Andrew / Kurtenkov, Mikhail / Gomes, Felipe Couto / Pisanu, Adolfo / Nardello, Oreste / Gambarini, Fabrizio / Aref, Hager / Angelis, Nicola De' / Agnoletti, Vanni / Biondi, Antonio / Vacante, Marco / Griggio, Giulia / Tutino, Roberta / Massani, Marco / Bisetto, Giovanni / Occhionorelli, Savino / Andreotti, Dario / Lacavalla, Domenico / Biffl, Walter L / Catena, Fausto

World journal of emergency surgery : WJES

2022 Volume 17, Issue 1, Page(s) 61

Abstract: Background: The incidence of the highly morbid and potentially lethal gangrenous cholecystitis was reportedly increased during the COVID-19 pandemic. The aim of the ChoCO-W study was to compare the clinical findings and outcomes of acute cholecystitis ... ...

Abstract	Background: The incidence of the highly morbid and potentially lethal gangrenous cholecystitis was reportedly increased during the COVID-19 pandemic. The aim of the ChoCO-W study was to compare the clinical findings and outcomes of acute cholecystitis in patients who had COVID-19 disease with those who did not. Methods: Data were prospectively collected over 6 months (October 1, 2020, to April 30, 2021) with 1-month follow-up. In October 2020, Delta variant of SARS CoV-2 was isolated for the first time. Demographic and clinical data were analyzed and reported according to the STROBE guidelines. Baseline characteristics and clinical outcomes of patients who had COVID-19 were compared with those who did not. Results: A total of 2893 patients, from 42 countries, 218 centers, involved, with a median age of 61.3 (SD: 17.39) years were prospectively enrolled in this study; 1481 (51%) patients were males. One hundred and eighty (6.9%) patients were COVID-19 positive, while 2412 (93.1%) were negative. Concomitant preexisting diseases including cardiovascular diseases (p < 0.0001), diabetes (p < 0.0001), and severe chronic obstructive airway disease (p = 0.005) were significantly more frequent in the COVID-19 group. Markers of sepsis severity including ARDS (p < 0.0001), PIPAS score (p < 0.0001), WSES sepsis score (p < 0.0001), qSOFA (p < 0.0001), and Tokyo classification of severity of acute cholecystitis (p < 0.0001) were significantly higher in the COVID-19 group. The COVID-19 group had significantly higher postoperative complications (32.2% compared with 11.7%, p < 0.0001), longer mean hospital stay (13.21 compared with 6.51 days, p < 0.0001), and mortality rate (13.4% compared with 1.7%, p < 0.0001). The incidence of gangrenous cholecystitis was doubled in the COVID-19 group (40.7% compared with 22.3%). The mean wall thickness of the gallbladder was significantly higher in the COVID-19 group [6.32 (SD: 2.44) mm compared with 5.4 (SD: 3.45) mm; p < 0.0001]. Conclusions: The incidence of gangrenous cholecystitis is higher in COVID patients compared with non-COVID patients admitted to the emergency department with acute cholecystitis. Gangrenous cholecystitis in COVID patients is associated with high-grade Clavien-Dindo postoperative complications, longer hospital stay and higher mortality rate. The open cholecystectomy rate is higher in COVID compared with non -COVID patients. It is recommended to delay the surgical treatment in COVID patients, when it is possible, to decrease morbidity and mortality rates. COVID-19 infection and gangrenous cholecystistis are not absolute contraindications to perform laparoscopic cholecystectomy, in a case by case evaluation, in expert hands.
Language	English
Publishing date	2022-12-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2233734-9
ISSN	1749-7922 ; 1749-7922
ISSN (online)	1749-7922
ISSN	1749-7922
DOI	10.1186/s13017-022-00466-4
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Article ; Online: Global attitudes in the management of acute appendicitis during COVID-19 pandemic

Ielpo, B. / Podda, M. / Pellino, G. / Pata, F. / Caruso, R. / Gravante, G. / Di Saverio, S. / Gallo, G. / Lui, R. / Orengia, A. / Chowdary, A. / Kulkarni, A. / Kuvvetli, A. / Navarro, A. / Pisanu, A. / Smith, A. / Ibiricu, A. C. / Nacion, A. J. D. / Alsaleh, A. /

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J. / Bellato, V. / Goncalves, W. / Powers, W. F. / Grigg, W. / Bechstein, W. O. / Lim, Y. B. / Altinel, Y. / Golubovic, Z. / Balciscueta, Z.

ACIE Appy Study

2020

Abstract: Background: Surgical strategies are being adapted to face the COVID-19 pandemic. Recommendations on the management of acute appendicitis have been based on expert opinion, but very little evidence is available. This study addressed that dearth with a ... ...

Abstract	Background: Surgical strategies are being adapted to face the COVID-19 pandemic. Recommendations on the management of acute appendicitis have been based on expert opinion, but very little evidence is available. This study addressed that dearth with a snapshot of worldwide approaches to appendicitis. Methods: The Association of Italian Surgeons in Europe designed an online survey to assess the current attitude of surgeons globally regarding the management of patients with acute appendicitis during the pandemic. Questions were divided into baseline information, hospital organization and screening, personal protective equipment, management and surgical approach, and patient presentation before versus during the pandemic. Results: Of 744 answers, 709 (from 66 countries) were complete and were included in the analysis. Most hospitals were treating both patients with and those without COVID. There was variation in screening indications and modality used, with chest X-ray plus molecular testing (PCR) being the commonest (19·8 per cent). Conservative management of complicated and uncomplicated appendicitis was used by 6·6 and 2·4 per cent respectively before, but 23·7 and 5·3 per cent, during the pandemic (both P < 0·001). One-third changed their approach from laparoscopic to open surgery owing to the popular (but evidence-lacking) advice from expert groups during the initial phase of the pandemic. No agreement on how to filter surgical smoke plume during laparoscopy was identified. There was an overall reduction in the number of patients admitted with appendicitis and one-third felt that patients who did present had more severe appendicitis than they usually observe. Conclusion: Conservative management of mild appendicitis has been possible during the pandemic. The fact that some surgeons switched to open appendicectomy may reflect the poor guidelines that emanated in the early phase of SARS-CoV-2.
Keywords	covid19
Subject code	610
Language	English
Publishing country	it
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Surgeons' fear of getting infected by COVID19

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A global survey

2020

Keywords	covid19
Language	English
Publishing country	it
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of asymptomatic COVID-19 patients in global surgical practice during the COVID-19 pandemic

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2020

Keywords	covid19
Language	English
Publishing country	it
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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