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  1. Article: Specificity of

    Sasikumar, Arun

    Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

    2016  Volume 32, Issue 1, Page(s) 11–12

    Abstract: 68Ga-PSMA ligand PET/CT for imaging prostate cancer is a novel imaging technique, which is rapidly gaining popularity. Sufficient evidence has been accumulated in literature regarding the usefulness ... ...

    Abstract 68Ga-PSMA ligand PET/CT for imaging prostate cancer is a novel imaging technique, which is rapidly gaining popularity. Sufficient evidence has been accumulated in literature regarding the usefulness of
    Language English
    Publishing date 2016-08-17
    Publishing country India
    Document type Editorial
    ZDB-ID 2181722-4
    ISSN 0974-0244 ; 0972-3919
    ISSN (online) 0974-0244
    ISSN 0972-3919
    DOI 10.4103/0972-3919.198449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: 18F-PSMA-1007 PET/CT for Initial Staging of Renal Cell Carcinoma in an End-Stage Renal Disease Patient.

    Marafi, Fahad / Sasikumar, Arun / Aldaas, Mariam / Esmail, Abdulredh

    Clinical nuclear medicine

    2020  Volume 46, Issue 1, Page(s) e65–e67

    Abstract: A 46-year-old man with end-stage renal disease and renal cell carcinoma underwent F-FDG PET/CT for initial staging followed by F-PSMA-1007 PET/CT. Unlike F-FDG, which undergoes renal clearance, F-PSMA-1007 undergoes hepatobiliary clearance and thus ... ...

    Abstract A 46-year-old man with end-stage renal disease and renal cell carcinoma underwent F-FDG PET/CT for initial staging followed by F-PSMA-1007 PET/CT. Unlike F-FDG, which undergoes renal clearance, F-PSMA-1007 undergoes hepatobiliary clearance and thus generates superior quality images. F-PSMA-1007 PET/CT showed intense tracer-avid left renal mass lesion (FDG nonavid); lytic bone lesions (FDG avid) and single liver lesion (FDG nonavid). This case highlights the superiority of F-PSMA-1007 over F-FDG PET/CT in identifying primary lesion as well as metastatic sites in case of renal cell carcinoma even in the presence of end-stage renal disease.
    MeSH term(s) Carcinoma, Renal Cell/complications ; Carcinoma, Renal Cell/diagnostic imaging ; Carcinoma, Renal Cell/pathology ; Female ; Fluorine Radioisotopes ; Humans ; Kidney Failure, Chronic/complications ; Kidney Neoplasms/complications ; Kidney Neoplasms/diagnostic imaging ; Kidney Neoplasms/pathology ; Middle Aged ; Neoplasm Staging ; Niacinamide/analogs & derivatives ; Oligopeptides ; Positron Emission Tomography Computed Tomography
    Chemical Substances Fluorine Radioisotopes ; Oligopeptides ; PSMA-1007 ; Niacinamide (25X51I8RD4) ; Fluorine-18 (GZ5I74KB8G)
    Language English
    Publishing date 2020-10-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000003354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: 18F-PSMA 1007 Uptake in a Man With Metastatic Breast Cancer.

    Marafi, Fahad / Sasikumar, Arun / Alfeeli, Mahamoud / Thuruthel, Sanjay

    Clinical nuclear medicine

    2020  Volume 45, Issue 6, Page(s) e276–e278

    Abstract: A 72-year-old man, who is known with a case of metastatic carcinoma of the breast, was referred for F-PMSA 1007 PET/CT with clinical suspicion of synchronous prostate cancer. F-PSMA 1007 PET/CT scan detected no abnormal tracer concentrating lesion in the ...

    Abstract A 72-year-old man, who is known with a case of metastatic carcinoma of the breast, was referred for F-PMSA 1007 PET/CT with clinical suspicion of synchronous prostate cancer. F-PSMA 1007 PET/CT scan detected no abnormal tracer concentrating lesion in the prostate gland; however, abnormal tracer concentration was noted in soft tissue lesions in left breast, metastatic lymph nodes, and skeletal lesions. Compared with F-FDG PET/CT, more bone lesions were detected on F-PSMA 1007 imaging. The findings of our case open the possibility of imaging metastatic breast cancer with F-PSMA 1007 in men.
    MeSH term(s) Aged ; Breast Neoplasms, Male/diagnostic imaging ; Breast Neoplasms, Male/metabolism ; Breast Neoplasms, Male/pathology ; Fluorine Radioisotopes ; Humans ; Male ; Neoplasm Metastasis ; Niacinamide/analogs & derivatives ; Niacinamide/metabolism ; Oligopeptides/metabolism ; Positron Emission Tomography Computed Tomography
    Chemical Substances Fluorine Radioisotopes ; Oligopeptides ; PSMA-1007 ; Niacinamide (25X51I8RD4) ; Fluorine-18 (GZ5I74KB8G)
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000003013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: 68Ga-Prostate-Specific Membrane Antigen Focal Pulmonary Activity With No Corresponding CT Abnormality.

    Sasikumar, Arun / Thampan, Sam / Thomas, Nivya / Paul, Retcy

    Clinical nuclear medicine

    2020  Volume 46, Issue 2, Page(s) e88–e89

    Abstract: Abstract: We describe a case of 68Ga-prostate-specific membrane antigen PET/CT scan with focal tracer concentration in the lung without any abnormalities in the CT part. 18F-FDG focal uptake in lungs without corresponding CT lesions is described. Two ... ...

    Abstract Abstract: We describe a case of 68Ga-prostate-specific membrane antigen PET/CT scan with focal tracer concentration in the lung without any abnormalities in the CT part. 18F-FDG focal uptake in lungs without corresponding CT lesions is described. Two possible mechanisms proposed to explain this finding in FDG PET/CT scans are iatrogenic pulmonary microembolism and 18F-FDG-avid infection or inflammation that precedes structural findings. Logically, these proposed mechanisms seem to be applicable to 68Ga-prostate-specific membrane antigen as well. In our case, there were no features of any lung infection/inflammation, and the most plausible explanation would be iatrogenic microembolism.
    MeSH term(s) Edetic Acid/analogs & derivatives ; Edetic Acid/metabolism ; Gallium Isotopes ; Gallium Radioisotopes ; Humans ; Lung/diagnostic imaging ; Lung/metabolism ; Male ; Oligopeptides/metabolism ; Positron Emission Tomography Computed Tomography
    Chemical Substances Gallium Isotopes ; Gallium Radioisotopes ; Oligopeptides ; gallium 68 PSMA-11 ; Edetic Acid (9G34HU7RV0)
    Language English
    Publishing date 2020-10-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000003316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: 18F-PSMA 1007 Brain PET/CT Imaging in Glioma Recurrence.

    Marafi, Fahad / Sasikumar, Arun / Fathallah, Wael / Esmail, Abdulredh

    Clinical nuclear medicine

    2019  Volume 45, Issue 1, Page(s) e61–e62

    Abstract: A 64-year-old man with a known case of right parietal lobe glioblastoma multiforme operated on in August 2018 was referred for F-FDG PET/CT with a clinical suspicion of recurrence. He underwent F-FDG and F-PSMA 1007 scans. Both the scans showed intense ... ...

    Abstract A 64-year-old man with a known case of right parietal lobe glioblastoma multiforme operated on in August 2018 was referred for F-FDG PET/CT with a clinical suspicion of recurrence. He underwent F-FDG and F-PSMA 1007 scans. Both the scans showed intense tracer uptake in right parietal lobe lesion, which concurred with MRI findings of recurrent disease and was later proven on histopathologic examination as recurrence. Our case highlights the feasibility of F-PSMA 1007 PET/CT imaging of suspected glioblastoma recurrence. Considering its similarity to PSMA-617, it may be used as a surrogate imaging tracer for potential theranostic application using alpha or beta emitters.
    MeSH term(s) Brain/diagnostic imaging ; Brain/pathology ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/pathology ; Fluorine Radioisotopes ; Glioblastoma/diagnostic imaging ; Glioblastoma/pathology ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Niacinamide/analogs & derivatives ; Oligopeptides ; Positron Emission Tomography Computed Tomography ; Recurrence
    Chemical Substances Fluorine Radioisotopes ; Oligopeptides ; PSMA-1007 ; Niacinamide (25X51I8RD4) ; Fluorine-18 (GZ5I74KB8G)
    Language English
    Publishing date 2019-06-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000002668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: 18F-PSMA 1007 Uptake in Brain Metastases From Breast Cancer.

    Marafi, Fahad / Sasikumar, Arun / Alfeeli, Mahmoud / Fathallah, Wael

    Clinical nuclear medicine

    2019  Volume 45, Issue 2, Page(s) e77–e79

    Abstract: A 64-year-old woman with metastatic breast cancer on follow-up had suspicious recurrent brain metastases. She underwent F-FDG PET/CT, F-PSMA 1007 brain PET/CT, and brain MRI. F-PSMA 1007 showed intense tracer localization in the suspected recurrent brain ...

    Abstract A 64-year-old woman with metastatic breast cancer on follow-up had suspicious recurrent brain metastases. She underwent F-FDG PET/CT, F-PSMA 1007 brain PET/CT, and brain MRI. F-PSMA 1007 showed intense tracer localization in the suspected recurrent brain metastasis in right parietal lobe and also picked up 2 more metastatic brain lesions, which had concurrent findings of metastasis in subsequent MRI. Our case highlights the feasibility of F-PSMA 1007 PET/CT imaging of brain metastases from nonprostate cancers. It may be used as surrogate imaging tracer for potential theranostic application using alpha or beta emitters considering its similarity to PSMA-617.
    MeSH term(s) Biological Transport ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/metabolism ; Brain Neoplasms/secondary ; Breast Neoplasms/pathology ; Female ; Humans ; Middle Aged ; Niacinamide/analogs & derivatives ; Niacinamide/metabolism ; Oligopeptides/metabolism ; Positron Emission Tomography Computed Tomography
    Chemical Substances Oligopeptides ; PSMA-1007 ; Niacinamide (25X51I8RD4)
    Language English
    Publishing date 2019-11-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000002821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: 18F-PSMA 1007 in Suspected Renal Cell Carcinoma.

    Marafi, Fahad / Sasikumar, Arun / Al-Terki, Abdullatif / Alfeeli, Mahmoud

    Clinical nuclear medicine

    2020  Volume 45, Issue 5, Page(s) 377–378

    Abstract: A 60-year-old man with suspected right renal cell carcinoma underwent F-FDG PET/CT and F prostate-specific membrane antigen (PSMA) 1007 PET/CT scan. Compared with the F-FDG PET/CT scan, F-PSMA 1007 PET/CT showed intense tracer concentration in the ... ...

    Abstract A 60-year-old man with suspected right renal cell carcinoma underwent F-FDG PET/CT and F prostate-specific membrane antigen (PSMA) 1007 PET/CT scan. Compared with the F-FDG PET/CT scan, F-PSMA 1007 PET/CT showed intense tracer concentration in the primary tumor in the right kidney and intense tracer concentration consistently in all lung nodules. Unlike noted in previous pilot studies with Ga-PSMA, we observed that the primary renal tumor also showed intense tracer avidity with F-PSMA 1007. F-PSMA 1007 PET/CT may provide preoperative insight into possible etiology, histopathological probability of tumor type, staging information, and theranostic potentials in evaluation of suspected renal cell carcinoma.
    MeSH term(s) Carcinoma, Renal Cell/diagnostic imaging ; Fluorine Radioisotopes ; Humans ; Kidney Neoplasms/diagnostic imaging ; Male ; Middle Aged ; Niacinamide/analogs & derivatives ; Oligopeptides ; Positron Emission Tomography Computed Tomography/methods ; Radiopharmaceuticals
    Chemical Substances Fluorine Radioisotopes ; Oligopeptides ; PSMA-1007 ; Radiopharmaceuticals ; Niacinamide (25X51I8RD4)
    Language English
    Publishing date 2020-03-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000003002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography in a rare case of carcinoma stomach with concomitant silicosis.

    Sasikumar, Arun / Joy, Ajith / Unni, Madhavan / Madhavan, Jayaprakash

    Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

    2016  Volume 31, Issue 4, Page(s) 307–308

    Abstract: The role of fluorine-18 fluorodeoxyglucose. ( ...

    Abstract The role of fluorine-18 fluorodeoxyglucose. (
    Language English
    Publishing date 2016-02-29
    Publishing country India
    Document type Case Reports
    ZDB-ID 2181722-4
    ISSN 0974-0244 ; 0972-3919
    ISSN (online) 0974-0244
    ISSN 0972-3919
    DOI 10.4103/0972-3919.187470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Case of Carcinoma Breast with Unusually Large Tumor Thrombus in Superior Vena Cava Detected on

    Sasikumar, Arun / Baby, Anto / Jose, Mathews / Paul, Retcy Mary

    Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

    2017  Volume 32, Issue 4, Page(s) 374–376

    Abstract: A 60-year-old female with triple negative breast cancer, postsurgery, neoadjuvant chemotherapy and radiotherapy, on follow-up had facial puffiness and giddiness. ...

    Abstract A 60-year-old female with triple negative breast cancer, postsurgery, neoadjuvant chemotherapy and radiotherapy, on follow-up had facial puffiness and giddiness.
    Language English
    Publishing date 2017-10-24
    Publishing country India
    Document type Journal Article
    ZDB-ID 2181722-4
    ISSN 0974-0244 ; 0972-3919
    ISSN (online) 0974-0244
    ISSN 0972-3919
    DOI 10.4103/ijnm.IJNM_88_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: 68Ga-PSMA Uptake in an Incidentally Detected Gastrointestinal Stromal Tumor in a Case of Suspected Carcinoma Prostate.

    Sasikumar, Arun / Joy, Ajith / Pillai, Mra / S, Bindu / Sr, Sudin

    Clinical nuclear medicine

    2017  Volume 42, Issue 10, Page(s) e447–e448

    Abstract: A 74-year-old man with suspected prostate cancer and a previously negative transrectal ultrasound-guided prostate biopsy underwent Ga-PSMA PET/CT. Scan showed no abnormal tracer concentration in enlarged prostate gland to suggest prostate cancer. Note ... ...

    Abstract A 74-year-old man with suspected prostate cancer and a previously negative transrectal ultrasound-guided prostate biopsy underwent Ga-PSMA PET/CT. Scan showed no abnormal tracer concentration in enlarged prostate gland to suggest prostate cancer. Note was made of an incidentally detected well defined soft tissue lesion in the greater curvature of the stomach with moderate tracer concentration in its intraluminal portion. Biopsy of the lesion revealed gastrointestinal stromal tumor.
    MeSH term(s) Aged ; Biological Transport ; Biopsy ; Edetic Acid/analogs & derivatives ; Edetic Acid/metabolism ; Gastrointestinal Stromal Tumors/complications ; Gastrointestinal Stromal Tumors/diagnostic imaging ; Gastrointestinal Stromal Tumors/metabolism ; Gastrointestinal Stromal Tumors/pathology ; Humans ; Incidental Findings ; Male ; Oligopeptides/metabolism ; Positron Emission Tomography Computed Tomography ; Prostatic Neoplasms/complications
    Chemical Substances Oligopeptides ; gallium 68 PSMA-11 ; Edetic Acid (9G34HU7RV0)
    Language English
    Publishing date 2017-07-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000001774
    Database MEDical Literature Analysis and Retrieval System OnLINE

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