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  1. Article: [Malignant Lymphoma Involving Peripheral Nervous System and Skeletal Muscle].

    Sato, Ryota

    Brain and nerve = Shinkei kenkyu no shinpo

    2021  Volume 73, Issue 10, Page(s) 1099–1106

    Abstract: The 2016 revision of the WHO classification of lymphoid neoplasms has been published. Although pathological analysis is necessary for the diagnosis of malignant lymphoma, genetic analysis has become increasingly important in recent years. The diagnosis ... ...

    Abstract The 2016 revision of the WHO classification of lymphoid neoplasms has been published. Although pathological analysis is necessary for the diagnosis of malignant lymphoma, genetic analysis has become increasingly important in recent years. The diagnosis of malignant lymphoma in the peripheral nerves and skeletal muscles is challenging; hence, diagnosis based on genetic profiles is desirable. In this article, previous studies on malignant lymphoma in the peripheral nerves and skeletal muscles are summarized. Common clinical findings, radiological characteristics, and genetic tests were reviewed.
    MeSH term(s) Humans ; Lymphoma/diagnosis ; Muscle, Skeletal ; Peripheral Nervous System
    Language Japanese
    Publishing date 2021-10-06
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416201899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: [Neuromuscular Disorders in the Oldest-Old].

    Sato, Ryota

    Brain and nerve = Shinkei kenkyu no shinpo

    2020  Volume 72, Issue 12, Page(s) 1319–1330

    Abstract: Age-related changes in physical function are attracting attention in Japan. Sarcopenia is known as the loss of skeletal muscle mass and strength in the elderly. Secondary sarcopenia due to neuromuscular disorders should be considered in patients with ... ...

    Abstract Age-related changes in physical function are attracting attention in Japan. Sarcopenia is known as the loss of skeletal muscle mass and strength in the elderly. Secondary sarcopenia due to neuromuscular disorders should be considered in patients with sarcopenia. Providing appropriate medical care for patients with neuromuscular disorders will extend healthy life expectancy. In this review, previous studies on age-related changes in the neuromuscular system were summarized and the common neuromuscular disorders in the oldest-old were reviewed.
    MeSH term(s) Aged ; Aged, 80 and over ; Aging ; Humans ; Japan ; Muscle, Skeletal/pathology ; Neuromuscular Diseases/epidemiology ; Neuromuscular Diseases/therapy ; Sarcopenia/diagnosis ; Sarcopenia/epidemiology ; Sarcopenia/therapy
    Language Japanese
    Publishing date 2020-12-07
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416201689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: The importance of assessing left ventricular longitudinal function in presence of increased afterload.

    Santonocito, Cristina / Sato, Ryota / Dugar, Siddharth / Sanfilippo, Filippo

    Critical care (London, England)

    2024  Volume 28, Issue 1, Page(s) 21

    MeSH term(s) Humans ; Prospective Studies ; Subarachnoid Hemorrhage ; Ventricular Function, Left ; Myocardial Contraction ; Cardiomyopathies
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-024-04801-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Four-dimensional Flow Cardiac MRI for Hemodynamic Assessment of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy with Multiple Obstructions.

    Suwa, Kenichiro / Sato, Ryota / Iguchi, Keisuke / Maekawa, Yuichiro

    Radiology. Cardiothoracic imaging

    2023  Volume 5, Issue 5, Page(s) e230074

    Abstract: Four-dimensional (4D) flow cardiac MRI can be used to assess hemodynamics in patients with hypertrophic obstructive cardiomyopathy (HOCM) undergoing alcohol septal ablation (ASA). However, to the best of the authors' knowledge, no study has reported on ... ...

    Abstract Four-dimensional (4D) flow cardiac MRI can be used to assess hemodynamics in patients with hypertrophic obstructive cardiomyopathy (HOCM) undergoing alcohol septal ablation (ASA). However, to the best of the authors' knowledge, no study has reported on insufficient or successful ASA evaluated with 4D flow cardiac MRI in HOCM with multiple obstructions. This case report presents a 74-year-old female patient who was diagnosed with HOCM with left ventricular (LV) outflow tract obstruction and midventricular obstruction. Repeat ASA targeting the LV outflow tract the first time and the midventricle the second time was conducted. Four-dimensional flow cardiac MRI performed before ASA, after the first ASA, and after the second ASA showed serial changes in the flow pathway and acceleration at the midventricle. Supplemental material is available for this article. © RSNA, 2023.
    Language English
    Publishing date 2023-09-28
    Publishing country United States
    Document type Case Reports
    ISSN 2638-6135
    ISSN (online) 2638-6135
    DOI 10.1148/ryct.230074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Contribution of Complement, Microangiopathy and Inflammation in Idiopathic Inflammatory Myopathies.

    Honda, Masaya / Shimizu, Fumitaka / Sato, Ryota / Nakamori, Masayuki

    Journal of neuromuscular diseases

    2023  Volume 11, Issue 1, Page(s) 5–16

    Abstract: Purpose of review: Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group characterized by muscle weakness and skin symptoms and are categorized into six subtypes: dermatomyositis (DM), polymyositis (PM), anti-synthetase syndrome (ASS), ... ...

    Abstract Purpose of review: Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group characterized by muscle weakness and skin symptoms and are categorized into six subtypes: dermatomyositis (DM), polymyositis (PM), anti-synthetase syndrome (ASS), immune-mediated myopathy (IMNM), inclusion body myopathy (IBM), and overlap myositis. Myositis-specific autoantibodies were detected for the diagnosis and classification of IIM. This review highlights the pathogenic contributions of the complement system, microangiopathy, and inflammation in IIM.
    Recent findings: Deposition of complement around capillaries and/or the sarcolemma was observed in muscle biopsy specimens from patients with DM, ASS, and IMNM, suggesting the pathomechanism of complement-dependent muscle and endothelial cell injury. A recent study using human muscle microvascular endothelial cells showed that Jo-1 antibodies from ASS induce complement-dependent cellular cytotoxicity in vitro. Based on both clinical and pathological observations, antibody- and complement-mediated microangiopathy may contribute to the development of DM and anti-Jo-1 ASS. Juvenile DM is characterized by the loss of capillaries, perivascular inflammation, and small-vessel angiopathies, which may be related to microinfarction and perifascicular atrophy. Several serum biomarkers that reflect the IFN1 signature and microangiopathy are elevated in patients with DM. The pathological observation of myxovirus resistance protein A (MxA), which suggests a type 1 interferon (IFN1) signature in DM, supports the diagnosis and further understanding of the pathomechanism of IIM. A recent report showed that an increase in triggering receptor expressed on myeloid cells (TREM-1) around perimysial blood vessels and muscles in patients with IIM plays a role in triggering inflammation and promoting the migration of inflammatory cells by secreting proinflammatory cytokines, such as tumor necrosis factor α.
    Summary: The deposition of complement in muscles and capillaries is a characteristic feature of DM, ASS, and IMNM. Microangiopathy plays a pathogenic role in DM, possibly resulting in perifascicular atrophy. Further understanding of the detailed pathomechanism regarding complement, microangiopathy, and inflammation may lead to novel therapeutic approaches for IIM.
    MeSH term(s) Humans ; Capillaries/pathology ; Endothelial Cells/pathology ; Myositis/diagnosis ; Muscle, Skeletal/pathology ; Muscular Diseases/pathology ; Inflammation/pathology ; Atrophy/pathology
    Language English
    Publishing date 2023-12-16
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2214-3602
    ISSN (online) 2214-3602
    DOI 10.3233/JND-230168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cardiogenic shock complicating sepsis and septic shock: A national inpatient sample analysis.

    Sato, Ryota / Hasegawa, Daisuke / Nishida, Kazuki / Dugar, Siddharth

    Medicina intensiva

    2023  Volume 47, Issue 9, Page(s) 547–551

    MeSH term(s) Humans ; Shock, Cardiogenic/etiology ; Shock, Cardiogenic/therapy ; Shock, Septic/complications ; Shock, Septic/therapy ; Inpatients ; Sepsis/complications ; Myocardial Infarction/complications
    Language English
    Publishing date 2023-06-01
    Publishing country Spain
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medine.2023.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Measurement of the Adhesion Force of a Living Sessile Organism on Antifouling Coating Surfaces Prepared with Polysulfobetaine-Grafted Particles.

    Takeuchi, Kanae / Sato, Ryota / Nogata, Yasuyuki / Kobayashi, Motoyasu

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 49, Page(s) 17984–17992

    Abstract: An antifouling polymer brush-like structure was fabricated by a simple and versatile dip-coating method of sulfobetaine containing copolymer-grafted silica nanoparticles (SiNPs) and alkyl diiodide cross-linkers. Surface-initiated atom transfer radical ... ...

    Abstract An antifouling polymer brush-like structure was fabricated by a simple and versatile dip-coating method of sulfobetaine containing copolymer-grafted silica nanoparticles (SiNPs) and alkyl diiodide cross-linkers. Surface-initiated atom transfer radical copolymerization of 3-(
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c02686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Delayed retropharyngeal hematoma following a minor facial blunt trauma.

    Kitai, Yuya / Sato, Ryota

    Trauma case reports

    2021  Volume 32, Page(s) 100442

    Abstract: We described the case of 75 years old male patient with an airway obstruction due to retropharyngeal hematoma that developed after a minor blunt trauma to the face. The patient was not taking any anticoagulants or antiplatelet agents and did not have any ...

    Abstract We described the case of 75 years old male patient with an airway obstruction due to retropharyngeal hematoma that developed after a minor blunt trauma to the face. The patient was not taking any anticoagulants or antiplatelet agents and did not have any coagulopathy. This case report indicates that emergency physicians must be aware of the risk of delayed airway obstruction in elderly patients regardless of whether the patient is using anticoagulants or antiplatelet agents.
    Language English
    Publishing date 2021-02-20
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2835433-3
    ISSN 2352-6440 ; 2352-6440
    ISSN (online) 2352-6440
    ISSN 2352-6440
    DOI 10.1016/j.tcr.2021.100442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Prevalence and prognosis of hyperdynamic left ventricular systolic function in septic patients: a systematic review and meta-analysis.

    Sato, Ryota / Sanfilippo, Filippo / Hasegawa, Daisuke / Prasitlumkum, Narut / Duggal, Abhijit / Dugar, Siddharth

    Annals of intensive care

    2024  Volume 14, Issue 1, Page(s) 22

    Abstract: Purpose: The prevalence of hyperdynamic left ventricular (LV) systolic function in septic patients and its impact on mortality remain controversial. In this systematic review and meta-analysis, we investigated the prevalence and association of ... ...

    Abstract Purpose: The prevalence of hyperdynamic left ventricular (LV) systolic function in septic patients and its impact on mortality remain controversial. In this systematic review and meta-analysis, we investigated the prevalence and association of hyperdynamic LV systolic function with mortality in patients with sepsis.
    Methods: We searched MEDLINE, Cochrane Central Register of Controlled Trials, and Embase. Primary outcomes were the prevalence of hyperdynamic LV systolic function in adult septic patients and the associated short-term mortality as compared to normal LV systolic function. Hyperdynamic LV systolic function was defined using LV ejection fraction (LVEF) of 70% as cutoff. Secondary outcomes were heart rate, LV end-diastolic diameter (LVEDD), and E/e' ratio.
    Results: Four studies were included, and the pooled prevalence of hyperdynamic LV systolic function was 18.2% ([95% confidence interval (CI) 12.5, 25.8]; I
    Conclusion: The prevalence of hyperdynamic LV systolic function is not negligible in septic patients. Such a finding is associated with significantly higher short-term mortality as compared to normal LV systolic function.
    Language English
    Publishing date 2024-02-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2617094-2
    ISSN 2110-5820
    ISSN 2110-5820
    DOI 10.1186/s13613-024-01255-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Endosomal Toll-Like Receptors as Therapeutic Targets for Autoimmune Diseases.

    Miyake, Kensuke / Shibata, Takuma / Fukui, Ryutaro / Murakami, Yusuke / Sato, Ryota / Hiranuma, Ryosuke

    Advances in experimental medicine and biology

    2024  Volume 1444, Page(s) 97–108

    Abstract: Nucleic acid (NA)-sensing Toll-like receptors (TLRs) reside in the endosomal compartment of innate immune cells, such as macrophages and dendritic cells. NAs transported to the endosomal compartment are degraded by DNases and RNases. Degradation products, ...

    Abstract Nucleic acid (NA)-sensing Toll-like receptors (TLRs) reside in the endosomal compartment of innate immune cells, such as macrophages and dendritic cells. NAs transported to the endosomal compartment are degraded by DNases and RNases. Degradation products, including single-stranded DNA, oligoRNA, and nucleosides, are recognized by TLR7, TLR8, and TLR9 to drive the defense responses against pathogens. NA degradation influences endosomal TLR responses by generating and degrading TLR ligands. TLR ligand accumulation because of impaired NA degradation causes constitutive TLR activation, leading to autoinflammatory and autoimmune diseases. Furthermore, some genes associated with these diseases promote endosomal TLR responses. Therefore, endosomal TLRs are promising therapeutic targets for TLR-mediated inflammatory diseases, and novel drugs targeting TLRs are being developed.
    MeSH term(s) Humans ; Toll-Like Receptors ; Autoimmune Diseases/drug therapy ; Nucleic Acids/metabolism ; Macrophages/metabolism
    Chemical Substances Toll-Like Receptors ; Nucleic Acids
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410187-X
    ISSN 0065-2598
    ISSN 0065-2598
    DOI 10.1007/978-981-99-9781-7_7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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