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Article: [Development of a System to Use Patient's Information Which is Required at the Radiological Department].

Satoh, Akihiro

2016 Volume 72, Issue 4, Page(s) 319–325

Abstract: The purpose of this study is to develop a new system to get and share some data of a patient which are required for a radiological examination not using an electronic medical chart or a radiological information system (RIS), and also to demonstrate that ... ...

Abstract	The purpose of this study is to develop a new system to get and share some data of a patient which are required for a radiological examination not using an electronic medical chart or a radiological information system (RIS), and also to demonstrate that this system is operated on cloud technology. I used Java Enterprise Edition (Java EE) as a programing language and MySQL as a server software, and I used two laptops as hardware for client computer and server computer. For cloud computing, I hired a server of Google App Engine for Java (GAE). As a result, I could get some data of the patient required at his/her examination instantly using this system. This system also helps to improve the efficiency of examination. For example, it has been useful when I want to decide radiographic condition or to create CT images such as multi-planar reconstruction (MPR) or volume rendering (VR). When it comes to cloud computing, the GAE was used experimentally due to some legal restrictions. From the above points it is clear that this system has played an important role in radiological examinations, but there has been still few things which I have to resolve for cloud computing.
MeSH term(s)	Humans ; Medical Records Systems, Computerized ; Radiology Department, Hospital ; Radiology Information Systems ; Software
Language	Japanese
Publishing date	2016-04
Publishing country	Japan
Document type	English Abstract ; Journal Article
ZDB-ID	2269092-X
ISSN	1881-4883 ; 0369-4305
ISSN (online)	1881-4883
ISSN	0369-4305
DOI	10.6009/jjrt.2016_JSRT_72.4.319
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Article ; Online: Aromatic oil from lavender as an atopic dermatitis suppressant.

Sato, Haruna / Kato, Kosuke / Koreishi, Mayuko / Nakamura, Yoshimasa / Tsujino, Yoshio / Satoh, Ayano

PloS one

2024 Volume 19, Issue 1, Page(s) e0296408

Abstract: In atopic dermatitis (AD), nerves are abnormally stretched near the surface of the skin, making it sensitive to itching. Expression of neurotrophic factor Artemin (ARTN) involved in such nerve stretching is induced by the xenobiotic response (XRE) to air ...

Abstract	In atopic dermatitis (AD), nerves are abnormally stretched near the surface of the skin, making it sensitive to itching. Expression of neurotrophic factor Artemin (ARTN) involved in such nerve stretching is induced by the xenobiotic response (XRE) to air pollutants and UV radiation products. Therefore, AD can be monitored by the XRE response. Previously, we established a human keratinocyte cell line stably expressing a NanoLuc reporter gene downstream of XRE. We found that 6-formylindolo[3,2-b]carbazole (FICZ), a tryptophan metabolite and known inducer of the XRE, increased reporter and Artemin mRNA expression, indicating that FICZ-treated cells could be a model for AD. Lavender essential oil has been used in folk medicine to treat AD, but the scientific basis for its use is unclear. In the present study, we investigated the efficacy of lavender essential oil and its major components, linalyl acetate and linalool, to suppress AD and sensitize skin using the established AD model cell line, and keratinocyte and dendritic cell activation assays. Our results indicated that lavender essential oil from L. angustifolia and linalyl acetate exerted a strong AD inhibitory effect and almost no skin sensitization. Our model is useful in that it can circumvent the practice of using animal studies to evaluate AD medicines.
MeSH term(s)	Animals ; Humans ; Dermatitis, Atopic/drug therapy ; Lavandula ; Skin ; Monoterpenes
Chemical Substances	linalyl acetate (5K47SSQ51G) ; Monoterpenes
Language	English
Publishing date	2024-01-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0296408
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Article ; Online: Effects of psychogenic stress on oxidative stress and antioxidant capacity at different growth stages of rats: Experimental study.

Lee, Sangun / Itagaki, Atsunori / Satoh, Atsuko / Sugimoto, Issei / Saito, Takumi / Shibukawa, Yoshihiko / Tatehana, Haruka

PloS one

2024 Volume 19, Issue 4, Page(s) e0287421

Abstract: This study examined the psychogenic stress (PS) effects on changes in oxidative stress and the antioxidant capacity of an organism at different growth stages. The experimental animals were male Wistar rats of five different ages from growth periods (GPs) ...

Abstract	This study examined the psychogenic stress (PS) effects on changes in oxidative stress and the antioxidant capacity of an organism at different growth stages. The experimental animals were male Wistar rats of five different ages from growth periods (GPs) to old age. The growth stages were randomly classified into control (C) and experimental (PS) groups. The PS was performed using restraint and water immersion once daily for 3 h for 4 weeks. Reactive oxygen metabolites (d-ROMs) and the biological antioxidant potential (BAP) were measured before and after the experiment. In addition, the liver and adrenal glands were removed, and the wet weight was measured. The d-ROM and BAP of all growth stages given PS increased significantly. The d-ROM in the C group without PS increased significantly in GPs while decreased significantly in old-aged rats. In addition, the BAP of the C group in GP and early adulthood were all significantly elevated. There were significant differences in organ weights between the C and PS groups at all growth stages. Oxidative stress and antioxidant capacity differed depending on the organism's developmental status and growth stage, and PS also showed different effects. In particular, the variability in oxidative stress was remarkable, suggesting that the effect of PS was more significant in the organism's immature organs.
MeSH term(s)	Animals ; Oxidative Stress ; Antioxidants/metabolism ; Male ; Rats, Wistar ; Rats ; Stress, Psychological/metabolism ; Reactive Oxygen Species/metabolism ; Liver/metabolism ; Organ Size ; Adrenal Glands/metabolism ; Adrenal Glands/growth & development
Chemical Substances	Antioxidants ; Reactive Oxygen Species
Language	English
Publishing date	2024-04-16
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0287421
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Article ; Online: Ruptured internal carotid artery dorsal wall aneurysm; its clinical features and treatment.

Satoh, A

European journal of neurology

2010 Volume 17, Issue 10, Page(s) 1225–1226

MeSH term(s)	Carotid Artery, Internal/pathology ; Carotid Artery, Internal/surgery ; Carotid Artery, Internal, Dissection/diagnosis ; Carotid Artery, Internal, Dissection/surgery ; Carotid Artery, Internal, Dissection/therapy ; Humans ; Intracranial Aneurysm/diagnosis ; Intracranial Aneurysm/surgery ; Intracranial Aneurysm/therapy ; Neurosurgical Procedures/methods ; Neurosurgical Procedures/standards ; Neurosurgical Procedures/trends ; Vascular Surgical Procedures/methods ; Vascular Surgical Procedures/standards ; Vascular Surgical Procedures/trends
Language	English
Publishing date	2010-10
Publishing country	England
Document type	Editorial ; Introductory Journal Article
ZDB-ID	1280785-0
ISSN	1468-1331 ; 1351-5101 ; 1471-0552
ISSN (online)	1468-1331
ISSN	1351-5101 ; 1471-0552
DOI	10.1111/j.1468-1331.2010.03031.x
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Article ; Online: Baseline Body Composition and Physical Activity Level Recommended for Optimal Bone Mineral Density in Young Women.

Lee, Sangun / Fujita, Chikako / Satoh, Atsuko

Women's health reports (New Rochelle, N.Y.)

2022 Volume 3, Issue 1, Page(s) 351–358

Abstract: Aim: This study examined the influence of body composition and physical activity level (PAL) on bone mineral density (BMD) to determine the baseline values necessary for maintaining healthy trabecular bone and improving bone health in young women.: ... ...

Abstract	Aim: This study examined the influence of body composition and physical activity level (PAL) on bone mineral density (BMD) to determine the baseline values necessary for maintaining healthy trabecular bone and improving bone health in young women. Materials and methods: The subjects, consisting of healthy young women, were assigned to either a BMD-low (BMD-L) or BMD-high (BMD-H) group using the osteosonic index. PAL was measured for 1 week and rated on a scale from PAL-1 to 8 according to intensity levels (metabolic equivalents [METs]). The Wilcoxon rank-sum test was performed for intergroup comparisons. Results: The BMD-H group had significantly higher fat-free muscle mass, skeletal muscle index, and basic metabolic rate than the BMD-L group ( Discussion and conclusion: For young women in their early 20s, BMD may be associated with baseline physical fitness and strength, as determined by body composition, but it is not influenced by the duration of physical activity. A PAL ≥6.0 METs may improve or maintain the effect on BMD.
Language	English
Publishing date	2022-03-21
Publishing country	United States
Document type	Journal Article
ISSN	2688-4844
ISSN (online)	2688-4844
DOI	10.1089/whr.2021.0137
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Article ; Online: An Electron Tomographic Analysis of Giantin-Deficient Golgi Proposes a New Function of the Golgin Protein Family.

Satoh, Ayano / Hayashi-Nishino, Mitsuko / Nishino, Kunihiko

Methods in molecular biology (Clifton, N.J.)

2022 Volume 2557, Page(s) 235–246

Abstract: The Golgi apparatus is an organelle that mediates modifications, sorting, and transport of proteins and lipids. Golgins are a group of proteins with coiled-coil structures that localize to the Golgi and are thought to function as tethers to facilitate ... ...

Abstract	The Golgi apparatus is an organelle that mediates modifications, sorting, and transport of proteins and lipids. Golgins are a group of proteins with coiled-coil structures that localize to the Golgi and are thought to function as tethers to facilitate the docking of vesicles, Rab GTPases, and cytoskeleton components to the Golgi stack. Giantin is the longest golgin and has been thought to function as a tether for COPI vesicles along with other golgins, such as p115 and GM130. Contrary to our expectation that the loss of the tether will result in an increase in untethered COPI vesicles in the cytoplasm, our electron microscopy observations showed that the fenestrae normally present in Golgi cisternae were reduced upon Giantin knockdown. We also found that this structural change is accompanied by altered secretion of cargo proteins and cell surface glycosylation. These results indicate that there exists a correlation between Golgi structural changes caused by the loss of Giantin and Golgi function. Here, we describe electron tomography methods for the detection of structural changes in the Golgi.
MeSH term(s)	Golgi Matrix Proteins/metabolism ; Electron Microscope Tomography ; Electrons ; Membrane Proteins/metabolism ; Autoantigens/metabolism ; Golgi Apparatus/metabolism ; Coat Protein Complex I/metabolism
Chemical Substances	macrogolgin ; Golgi Matrix Proteins ; Membrane Proteins ; Autoantigens ; Coat Protein Complex I
Language	English
Publishing date	2022-12-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1940-6029
ISSN (online)	1940-6029
DOI	10.1007/978-1-0716-2639-9_15
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Article ; Online: Bead Implantation and Delivery of Exogenous Growth Factors.

Kashimoto, Rena / Furukawa, Saya / Yamamoto, Sakiya / Satoh, Akira

Methods in molecular biology (Clifton, N.J.)

2022 Volume 2562, Page(s) 209–216

Abstract: Genetic methods in axolotls (Ambystoma mexicanum) remain in their infancy which has hampered the study of limb regeneration. There is much room for advancement, especially with respect to spatiotemporal regulation of gene expression. Secreted growth ... ...

Abstract	Genetic methods in axolotls (Ambystoma mexicanum) remain in their infancy which has hampered the study of limb regeneration. There is much room for advancement, especially with respect to spatiotemporal regulation of gene expression. Secreted growth factors play a major role in each stage of regeneration. The use of slow-release beads is one of the most effective methods to control the spatiotemporal expression of secretory gene products. The topical administration of secreted factors by slow-release beads may also prove effective for future applications in non-regenerative animals and for medical applications in humans, in which genetic methods are not available. In this chapter, we describe a methodology for using and implanting slow-release beads to deliver exogenous growth factors to salamanders.
MeSH term(s)	Animals ; Humans ; Extremities/physiology ; Ambystoma mexicanum/genetics ; Intercellular Signaling Peptides and Proteins
Chemical Substances	Intercellular Signaling Peptides and Proteins
Language	English
Publishing date	2022-10-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1940-6029
ISSN (online)	1940-6029
DOI	10.1007/978-1-0716-2659-7_14
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Article: Constant light disrupts the circadian but not the circatidal rhythm in mangrove crickets

Satoh, Aya

Biological rhythm research. 2017 May 4, v. 48, no. 3

2017

Abstract: Mangrove crickets have a circatidal activity rhythm (~12.6Â h cycles) with a circadian modulation under constant darkness (DD), whereby activity levels are higher during subjective night low tides than subjective day low tides. This study explored the ... ...

Abstract	Mangrove crickets have a circatidal activity rhythm (~12.6Â h cycles) with a circadian modulation under constant darkness (DD), whereby activity levels are higher during subjective night low tides than subjective day low tides. This study explored the locomotor activity rhythm of mangrove crickets under constant light (LL). Under LL, the crickets also exhibited a clear circatidal activity rhythm with a free-running period of 12.6Â Â±Â 0.26Â h (meanÂ Â±Â SD, n =Â 6), which was not significantly different from that observed under DD. In contrast, activity levels were almost the same between subjective day and night, unlike those under DD, which were greater during subjective night. The loss of circadian modulation under LL may be explained by the suspension of the circadian clock in these conditions. These results strongly suggest that the circatidal activity rhythm is driven by its own clock system, distinct from the circadian clock.
Keywords	circadian rhythm ; Gryllidae ; locomotion ; tides
Language	English
Dates of publication	2017-0504
Size	p. 459-463.
Publishing place	Taylor & Francis
Document type	Article
ISSN	1744-4179
DOI	10.1080/09291016.2016.1275392
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response.

Kyunai, Yuki M / Sakamoto, Mika / Koreishi, Mayuko / Tsujino, Yoshio / Satoh, Ayano

PloS one

2023 Volume 18, Issue 2, Page(s) e0281516

Abstract: GlycoMaple is a new tool to predict glycan structures based on the expression levels of 950 genes encoding glycan biosynthesis-related enzymes and proteins using RNA-seq data. The antioxidant response, protecting cells from oxidative stress, has been ... ...

Abstract	GlycoMaple is a new tool to predict glycan structures based on the expression levels of 950 genes encoding glycan biosynthesis-related enzymes and proteins using RNA-seq data. The antioxidant response, protecting cells from oxidative stress, has been focused on because its activation may relieve pathological conditions, such as neurodegenerative diseases. Genes involved in the antioxidant response are defined within the GO:0006979 category, including 441 human genes. Fifteen genes overlap between the glycan biosynthesis-related genes defined by GlycoMaple and the antioxidant response genes defined by GO:0006979, one of which is FUT8. 5-Hydroxy-4-phenyl-butenolide (5H4PB) extracted from Chinese aromatic vinegar induces the expression of a series of antioxidant response genes that protect cells from oxidative stress via activation of the nuclear factor erythroid 2-related factor 2-antioxidant response element pathway. Here, we show that FUT8 is upregulated in both our RNA-seq data set of 5H4PB-treated cells and publicly available RNA-seq data set of cells treated with another antioxidant, sulforaphane. Applying our RNA-seq data set to GlycoMaple led to a prediction of an increase in the core fucose of N-glycan that was confirmed by flow cytometry using a fucose-binding lectin. These results suggest that FUT8 and core fucose expression may increase upon the antioxidant response.
MeSH term(s)	Humans ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Fucose/metabolism ; Fucosyltransferases/genetics ; Fucosyltransferases/metabolism ; Oxidative Stress ; Polysaccharides
Chemical Substances	Antioxidants ; Fucose (28RYY2IV3F) ; Fucosyltransferases (EC 2.4.1.-) ; Polysaccharides ; Glycoprotein 6-alpha-L-fucosyltransferase (EC 2.4.1.68)
Language	English
Publishing date	2023-02-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0281516
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Article ; Online: A Primer on Deep Learning-Based Cellular Image Classification of Changes in the Spatial Distribution of the Golgi Apparatus After Experimental Manipulation.

Takao, Daisuke / Kyunai, Yuki M / Okada, Yasushi / Satoh, Ayano

Methods in molecular biology (Clifton, N.J.)

2022 Volume 2557, Page(s) 275–285

Abstract: The visual classification of cell images according to differences in the spatial patterns of subcellular structure is an important methodology in cell and developmental biology. Experimental perturbation of cell function can induce changes in the spatial ...

Abstract	The visual classification of cell images according to differences in the spatial patterns of subcellular structure is an important methodology in cell and developmental biology. Experimental perturbation of cell function can induce changes in the spatial distribution of organelles and their associated markers or labels. Here, we demonstrate how to achieve accurate, unbiased, high-throughput image classification using an artificial intelligence (AI) algorithm. We show that a convolutional neural network (CNN) algorithm can classify distinct patterns of Golgi images after drug or siRNA treatments, and we review our methods from cell preparation to image acquisition and CNN analysis.
MeSH term(s)	Deep Learning ; Artificial Intelligence ; Neural Networks, Computer ; Algorithms ; Golgi Apparatus
Language	English
Publishing date	2022-12-13
Publishing country	United States
Document type	Review ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1940-6029
ISSN (online)	1940-6029
DOI	10.1007/978-1-0716-2639-9_18
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