LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 3 of total 3

Search options

  1. Article ; Online: Polyarthrite rhumatoïde: la rémission sans biothérapie? L’expérience du Burkina Faso (Afrique de l’Ouest).

    Ouédraogo, Aboubakar / Kabore, Fulgence / Zabsonré/Tiendrebéogo, Wendlasida Joëlle Stéphanie / Nonguierma, Victor / Savadogo, Binta / Abassiri, Kantiga Aida Eudoxie / Zongo, Yamyellé Enselme / Damade, Richard / Ouédraogo, Dieu-Donné

    The Pan African medical journal

    2024  Volume 47, Page(s) 12

    Abstract: Introduction: the objective of this study was to evaluate the therapeutic response of patients treated with disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis (RA).: Methods: descriptive and analytical single-center cross- ... ...

    Title translation Rheumatoid arthritis: remission without biotherapy? The experience of Burkina Faso (West Africa).
    Abstract Introduction: the objective of this study was to evaluate the therapeutic response of patients treated with disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis (RA).
    Methods: descriptive and analytical single-center cross-sectional study conducted in Burkina Faso from January 2019 to December 2021 in patients with RA meeting American Rheumatism Association/European League against rheumatism criteria. Therapeutic response was assessed according to the criteria of the European League Against Rheumatism, the clinical disease activity index and the simplified disease activity Index after at least six months of treatment.
    Results: one hundred and three patients, including 85 women were included. The average age of the patients was 50.14 years ± 15.04 years. Eighty-seven patients (84.47%) were ACPA positive and 50 patients (48.54%) had radiological damage at inclusion. The mean DAS28-CRP, CDAI and SDAI were 5.17, respectively; 32.16 and 35.48 at inclusion compared to 2.53; 7.83 and 8.76 after at least six months of treatment (p<0.0001). Ninety-six patients (93.20%) were treated with methotrexate. According to the criteria of the European League Against Rheumatism, 89 patients (86.41%) were good responders, 62 patients (60.19%) were in remission. Major improvement was observed in 53 patients (51.46%) as assessed by the Clinical Disease Activity Index and the Simplified Disease Activity Index.
    Conclusion: despite the unavailability of biotherapies in sub-Saharan Africa, remission of RA can be obtained by optimizing treatment with DMARDs and "tight control".
    MeSH term(s) Humans ; Female ; United States ; Middle Aged ; Burkina Faso ; Cross-Sectional Studies ; Remission Induction ; Severity of Illness Index ; Arthritis, Rheumatoid/drug therapy ; Antirheumatic Agents/therapeutic use ; Biological Therapy ; Treatment Outcome
    Chemical Substances Antirheumatic Agents
    Language French
    Publishing date 2024-01-10
    Publishing country Uganda
    Document type English Abstract ; Journal Article
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2024.47.12.37537
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Epidemiology of rheumatic diseases: a cohort of 23,550 patients in rheumatology clinics in Burkina Faso

    Tiendrébéogo, Joelle W. S. / Kaboré, Fulgence / Sougué, Charles / Sankara, Virginie / Zongo, Enselme / Savadogo, Binta / Abassiri, Aïda / Ayouba-Tinni, Ismaël / Ouedraogo, Aboubakar / Yaméogo, Nadège W. / Ouedraogo, Dieu-Donné

    Clin Rheumatol. 2023 Feb., v. 42, no. 2, p. 371-376

    2023  , Page(s) 371–376

    Abstract: OBJECTIVE: The aim of this work is to study the epidemiological characteristics of rheumatic conditions in a cohort of 23,550 patients followed up in Ouagadougou, Burkina Faso. PATIENTS AND METHODS: This was a descriptive observational study on records ... ...

    Abstract OBJECTIVE: The aim of this work is to study the epidemiological characteristics of rheumatic conditions in a cohort of 23,550 patients followed up in Ouagadougou, Burkina Faso. PATIENTS AND METHODS: This was a descriptive observational study on records conducted from February 2006 to December 2019 in Ouagadougou (Burkina Faso). All patients seen in rheumatology consultation in the city of Ouagadougou were included. The diagnosis of mechanical and degenerative osteoarthropathies was based on clinical and radiological findings; osteoarticular infection was based on clinical and biological findings. The diagnosis of gout was based on the clinical findings, uricemia, and/or the presence of sodium urate crystals in the synovial fluid on microscope. The diagnosis of rheumatoid arthritis and systemic lupus erythematosus was based on the ACR/EULAR criteria. RESULTS: In total, 23,550 patients were included in the study. These were 14,995 female patients (63.70%) and 2555 male patients (36.30%). The average age of patients was 49.61 ± 15.36 years with extremes of 9 months to 120 years. Degenerative osteoarthropathies were the most common presentation (13,377 patients; 59.35%) followed by tendinopathies (2199 patients; 9.34%); chronic inflammatory rheumatism was in third place (841 patients; 3.57%) led by rheumatoid arthritis (434 patients); 51.61% of chronic inflammatory rheumatism, systemic lupus erythematosus and ankylosing spondylitis accounted for 71 patients (0.4%) and 63 patients (0.27%), respectively. CONCLUSION: The epidemiology of rheumatic conditions is characterized by its diversity in hospital setting. The scarcity of some conditions such as systemic lupus erythematosus, psoriatic arthritis, and ankylosing spondylitis has been confirmed in this cohort. Key Points • Twenty-three thousand five hundred and fifty patients were included in the study • Rheumatoid arthritis was the most frequent (51.61%) chronic inflammatory rheumatism • Contrary to studies from Europe and America, systemic lupus seems rare in our series
    Keywords epidemiology ; females ; gout ; hospitals ; lupus erythematosus ; males ; observational studies ; rheumatoid arthritis ; sodium ; synovial fluid ; Burkina Faso ; Europe
    Language English
    Dates of publication 2023-02
    Size p. 371-376
    Publishing place Springer International Publishing
    Document type Article ; Online
    ZDB-ID 604755-5
    ISSN 0770-3198
    ISSN 0770-3198
    DOI 10.1007/s10067-022-06470-y
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  3. Article ; Online: Epidemiology of rheumatic diseases: a cohort of 23,550 patients in rheumatology clinics in Burkina Faso.

    Tiendrébéogo, Joelle W S / Kaboré, Fulgence / Sougué, Charles / Sankara, Virginie / Zongo, Enselme / Savadogo, Binta / Abassiri, Aïda / Ayouba-Tinni, Ismaël / Ouedraogo, Aboubakar / Yaméogo, Nadège W / Ouedraogo, Dieu-Donné

    Clinical rheumatology

    2022  Volume 42, Issue 2, Page(s) 371–376

    Abstract: Objective: The aim of this work is to study the epidemiological characteristics of rheumatic conditions in a cohort of 23,550 patients followed up in Ouagadougou, Burkina Faso.: Patients and methods: This was a descriptive observational study on ... ...

    Abstract Objective: The aim of this work is to study the epidemiological characteristics of rheumatic conditions in a cohort of 23,550 patients followed up in Ouagadougou, Burkina Faso.
    Patients and methods: This was a descriptive observational study on records conducted from February 2006 to December 2019 in Ouagadougou (Burkina Faso). All patients seen in rheumatology consultation in the city of Ouagadougou were included. The diagnosis of mechanical and degenerative osteoarthropathies was based on clinical and radiological findings; osteoarticular infection was based on clinical and biological findings. The diagnosis of gout was based on the clinical findings, uricemia, and/or the presence of sodium urate crystals in the synovial fluid on microscope. The diagnosis of rheumatoid arthritis and systemic lupus erythematosus was based on the ACR/EULAR criteria.
    Results: In total, 23,550 patients were included in the study. These were 14,995 female patients (63.70%) and 2555 male patients (36.30%). The average age of patients was 49.61 ± 15.36 years with extremes of 9 months to 120 years. Degenerative osteoarthropathies were the most common presentation (13,377 patients; 59.35%) followed by tendinopathies (2199 patients; 9.34%); chronic inflammatory rheumatism was in third place (841 patients; 3.57%) led by rheumatoid arthritis (434 patients); 51.61% of chronic inflammatory rheumatism, systemic lupus erythematosus and ankylosing spondylitis accounted for 71 patients (0.4%) and 63 patients (0.27%), respectively.
    Conclusion: The epidemiology of rheumatic conditions is characterized by its diversity in hospital setting. The scarcity of some conditions such as systemic lupus erythematosus, psoriatic arthritis, and ankylosing spondylitis has been confirmed in this cohort. Key Points • Twenty-three thousand five hundred and fifty patients were included in the study • Rheumatoid arthritis was the most frequent (51.61%) chronic inflammatory rheumatism • Contrary to studies from Europe and America, systemic lupus seems rare in our series.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Middle Aged ; Aged ; Spondylitis, Ankylosing ; Rheumatology ; Rheumatic Fever ; Burkina Faso/epidemiology ; Rheumatic Diseases/epidemiology ; Rheumatic Diseases/diagnosis ; Arthritis, Rheumatoid/epidemiology ; Arthritis, Rheumatoid/diagnosis ; Lupus Erythematosus, Systemic/diagnosis
    Language English
    Publishing date 2022-12-10
    Publishing country Germany
    Document type Observational Study ; Journal Article
    ZDB-ID 604755-5
    ISSN 1434-9949 ; 0770-3198
    ISSN (online) 1434-9949
    ISSN 0770-3198
    DOI 10.1007/s10067-022-06470-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top