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  1. Article ; Online: Covalent binding of food-derived blue pigment phycocyanobilin to bovine β-lactoglobulin under physiological conditions.

    Minic, Simeon / Radomirovic, Mirjana / Savkovic, Nina / Radibratovic, Milica / Mihailovic, Jelena / Vasovic, Tamara / Nikolic, Milan / Milcic, Milos / Stanic-Vucinic, Dragana / Cirkovic Velickovic, Tanja

    Food chemistry

    2018  Volume 269, Page(s) 43–52

    Abstract: In this study, we investigated structural aspects of covalent binding of food derived blue pigment phycocyanobilin (PCB) to bovine β-lactoglobulin (BLG), major whey protein, by spectroscopic, electrophoretic, mass spectrometry and computational methods. ... ...

    Abstract In this study, we investigated structural aspects of covalent binding of food derived blue pigment phycocyanobilin (PCB) to bovine β-lactoglobulin (BLG), major whey protein, by spectroscopic, electrophoretic, mass spectrometry and computational methods. At physiological pH (7.2), we found that covalent pigment binding via free cysteine residue is slow (k
    MeSH term(s) Animals ; Binding Sites ; Cattle ; Hydrogen-Ion Concentration ; Lactoglobulins/chemistry ; Phycobilins/chemistry ; Phycocyanin/chemistry ; Pigmentation
    Chemical Substances Lactoglobulins ; Phycobilins ; Phycocyanin (11016-15-2) ; phycocyanobilin (36NUT04V2K)
    Language English
    Publishing date 2018-06-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2018.06.138
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  2. Article: RECOVERY OF REPRODUCTIVE ABILITY BY HOMOLOGOUS TESTES-DNA OF RATS IRRADIATED DURING THE INFANTILE PERIOD.

    SAVKOVIC, N

    Nature

    1964  Volume 203, Page(s) 1297–1298

    MeSH term(s) Animals ; Animals, Newborn ; Cysteamine ; DNA ; Humans ; Male ; Metabolism ; Pathology ; Radiation Genetics ; Radiation Injuries ; Radiation Injuries, Experimental ; Rats ; Reproduction ; Research ; Testis
    Chemical Substances Cysteamine (5UX2SD1KE2) ; DNA (9007-49-2)
    Language English
    Publishing date 1964-09-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/2031297a0
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    Zs.A 26: Show issues Location:
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  3. Article: EFFECT OF CHEMICAL PROTECTIVE AGENTS (CYSTEAMINE AND BETA-AMINOETHYLISOTHIURONIUM (AET) CL HCL) AND HOMOLOGOUS TESTES-DNA ON THE DEATH-RATE OF THE PROGENY OF A FIRST GENERATION ORIGINATING FROM MALE RATS IRRADIATED IN THE INFANTILE PERIOD.

    SAVKOVIC, N

    Nature

    1964  Volume 203, Page(s) 1393

    MeSH term(s) Animals ; Animals, Newborn ; Cysteamine ; DNA ; Dwarfism ; Humans ; Male ; Mutation ; Protective Agents ; Radiation Genetics ; Rats ; Reproduction ; Research ; Testis ; beta-Aminoethyl Isothiourea
    Chemical Substances Protective Agents ; beta-Aminoethyl Isothiourea (151-16-6) ; Cysteamine (5UX2SD1KE2) ; DNA (9007-49-2)
    Language English
    Publishing date 1964-09-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/2031393a0
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  4. Article: RECOVERY EFFECTS OF HOMOLOGOUS TESTES DNA INJECTED INTO TOTAL-BODY IRRADIATED (600 R) INFANTILE RATS AND MICE.

    SAVKOVIC, N

    Nature

    1963  Volume 200, Page(s) 1073–1074

    MeSH term(s) Animals ; Animals, Newborn ; DNA ; Humans ; Male ; Mice ; Pharmacology ; Physiological Phenomena ; Radiation Effects ; Rats ; Research ; Testis
    Chemical Substances DNA (9007-49-2)
    Language English
    Publishing date 1963-12-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/2001073a0
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  5. Article: The effects of cysteamine and AET Cl HCl on the induction of meiotic chromosome rearrangements in irradiated male mice.

    Savkovic, N / Pecevski, J

    Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie

    1974  Volume 16, Issue 1, Page(s) 85–89

    MeSH term(s) Animals ; Chromosome Aberrations ; Chromosomes/radiation effects ; Cysteamine/pharmacology ; DNA/radiation effects ; Male ; Meiosis ; Mice ; Mice, Inbred C3H ; Radiation Dosage ; Radiation Genetics ; Spermatozoa/cytology ; Testis/cytology ; beta-Aminoethyl Isothiourea/pharmacology
    Chemical Substances beta-Aminoethyl Isothiourea (151-16-6) ; Cysteamine (5UX2SD1KE2) ; DNA (9007-49-2)
    Language English
    Publishing date 1974-03
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 218119-8
    ISSN 0008-4093
    ISSN 0008-4093
    DOI 10.1139/g74-008
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    Zs.A 1266: Show issues Location:
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  6. Article: The frequency of chromosomal translocations among the offspring of locally irradiated rats.

    Savković, N / Pecevski, J

    Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie

    1971  Volume 13, Issue 2, Page(s) 283–286

    MeSH term(s) Animals ; Chromosome Aberrations ; Karyotyping ; Male ; Meiosis ; Radiation Genetics ; Rats ; Spermatozoa/cytology ; Spermatozoa/radiation effects ; Testis/radiation effects
    Language English
    Publishing date 1971-06
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 218119-8
    ISSN 0008-4093
    ISSN 0008-4093
    DOI 10.1139/g71-046
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  7. Article: The effect of X-irradiation on the fertility and on the induction of meiotic chromosome rearrangements in mice and their first generation.

    Savković, N / Pecevski, J / Marić, N / Radivojević, D

    Strahlentherapie

    1980  Volume 156, Issue 6, Page(s) 437–440

    Abstract: The effect of whole-body or local irradiation with X-rays at a dose of 600 R on the induction of chromosomal translocations in the diakinesis metaphase I of the meiosis in treated and F1 males has been examined along with their fertility. Our results ... ...

    Abstract The effect of whole-body or local irradiation with X-rays at a dose of 600 R on the induction of chromosomal translocations in the diakinesis metaphase I of the meiosis in treated and F1 males has been examined along with their fertility. Our results show the high percentage of mortality in whole-body irradiated mice. The percentage of the fertility was 25% in whole-body, and 93.7% in locally irradiated males. The testis weight was also reduced. The percentage of chromosomal translocations in diakinesis, metaphase I, or the meiosis was higher after whole-body irradiation than after local irradiation. In F1 males both types of irradiation induced chromosomal translocations.
    MeSH term(s) Animals ; Fertility/radiation effects ; Male ; Meiosis/radiation effects ; Metaphase ; Mice ; Organ Size ; Radiation Dosage ; Testis/pathology ; Translocation, Genetic
    Language English
    Publishing date 1980-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 205169-2
    ISSN 0039-2073
    ISSN 0039-2073
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  8. Article: Recovery effect of heterologous liver, kidney, thymus and spleen-DNA injected into total-body irradiated (600 R) adult male mice and infantile male rats.

    Savkovic, N / Kacaki, J

    Strahlentherapie

    1967  Volume 133, Issue 3, Page(s) 406–410

    MeSH term(s) Animals ; Animals, Newborn ; DNA/therapeutic use ; Injections, Intraperitoneal ; Kidney ; Liver ; Male ; Mice ; Radiation Injuries, Experimental/prevention & control ; Rats ; Spleen ; Testis ; Thymus Gland ; Tissue Extracts/therapeutic use
    Chemical Substances Tissue Extracts ; DNA (9007-49-2)
    Language English
    Publishing date 1967-07
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 205169-2
    ISSN 0039-2073
    ISSN 0039-2073
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  9. Article: RECOVERY EFFECTS OF HOMOLOGOUS LIVER DEOXYRIBONUCLEIC ACID INJECTED INTO TOTAL-BODY IRRADIATED (600 R) INFANTILE RATS.

    SAVKOVIC, N / BECAREVIC, A

    Strahlentherapie

    1965  Volume 126, Page(s) 465–467

    MeSH term(s) DNA ; Liver/enzymology ; Macromolecular Substances ; Pharmacology ; Radiation Injuries ; Radiation Injuries, Experimental ; Rats ; Research
    Chemical Substances Macromolecular Substances ; DNA (9007-49-2)
    Language English
    Publishing date 1965-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 205169-2
    ISSN 0039-2073
    ISSN 0039-2073
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  10. Article: The effect of mitomycin on the fertility and the induction of meiotic chromosome rearrangements in mice and their first generation progeny.

    Savković, N / Green, S / Pecevski, J / Marić, N

    Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie

    1977  Volume 19, Issue 3, Page(s) 387–393

    Abstract: The dose dependent effects of chronic application of Mitomycin C(MC) on the induction of chromosomal translocations in treated animals and F1 males and on their fertility have been examined. The C3H strain mice used in the present experiments were ... ...

    Abstract The dose dependent effects of chronic application of Mitomycin C(MC) on the induction of chromosomal translocations in treated animals and F1 males and on their fertility have been examined. The C3H strain mice used in the present experiments were treated with MC during eight successive weeks in doses of 0.05 mg/kg and 0.1 mg/kg of body weight. 75 males were treated (25 males per dose and 25 males as controls). Immediately after the chronic treatment they were mated with normal females and were tested for their reproductive performance. The fertility of males was estimated from the number of pregnant females after one week of being together. After that all males were sacrificed and prepared for cytological analysis. No chromosomal translocations were found in diakinesis-metaphase I of meiosis. Data from the study of fertility showed that all treated males were fertile, but all females were not pregnant. The tests of all sterile, semisterile and fertile F1 males showed that F1 males could not be identified as heterozygous translocation carriers.
    MeSH term(s) Animals ; Chromosomes/drug effects ; Dose-Response Relationship, Drug ; Female ; Fertility/drug effects ; Male ; Meiosis ; Mice ; Mice, Inbred C3H ; Mitomycins/pharmacology ; Testis/cytology ; Translocation, Genetic
    Chemical Substances Mitomycins
    Language English
    Publishing date 1977-09
    Publishing country Canada
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 218119-8
    ISSN 0008-4093
    ISSN 0008-4093
    DOI 10.1139/g77-042
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