Artikel ; Online: Characteristics of cells with engraftment capacity within CD34+ cell population upon G-CSF and Plerixafor mobilization.
2020 Band 34, Heft 12, Seite(n) 3370–3381
Abstract: In the context of hematopoietic cell transplantation, hematopoietic stem cells and progenitor cells (HSC and HPC) are usually collected by apheresis following their mobilization by G-CSF alone or in combination with Plerixafor® when patients fail to ... ...
| Abstract | In the context of hematopoietic cell transplantation, hematopoietic stem cells and progenitor cells (HSC and HPC) are usually collected by apheresis following their mobilization by G-CSF alone or in combination with Plerixafor® when patients fail to respond to G-CSF alone. In medical practice, the quality of the hematopoietic graft is based on CD34 |
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| Mesh-Begriff(e) | Animals ; Antigens, CD34/metabolism ; Child ; Female ; Granulocyte Colony-Stimulating Factor/metabolism ; Hematopoietic Stem Cell Mobilization/methods ; Hematopoietic Stem Cell Transplantation/methods ; Hematopoietic Stem Cells/drug effects ; Hematopoietic Stem Cells/metabolism ; Heterocyclic Compounds/therapeutic use ; Humans ; Lymphoma/drug therapy ; Lymphoma/metabolism ; Male ; Mice ; Middle Aged ; Multiple Myeloma/drug therapy ; Multiple Myeloma/metabolism ; Stem Cells/drug effects ; Stem Cells/metabolism | |||||
| Chemische Substanzen | Antigens, CD34 ; Heterocyclic Compounds ; Granulocyte Colony-Stimulating Factor (143011-72-7) ; plerixafor (S915P5499N) | |||||
| Sprache | Englisch | |||||
| Erscheinungsdatum | 2020-07-20 | |||||
| Erscheinungsland | England | |||||
| Dokumenttyp | Journal Article ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 807030-1 | |||||
| ISSN | 1476-5551 ; 0887-6924 | |||||
| ISSN (online) | 1476-5551 | |||||
| ISSN | 0887-6924 | |||||
| DOI | 10.1038/s41375-020-0982-y | |||||
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| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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