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Article ; Online: CD8+ T cell differentiation status correlates with the feasibility of sustained unresponsiveness following oral immunotherapy

Abhinav Kaushik / Diane Dunham / Xiaorui Han / Evan Do / Sandra Andorf / Sheena Gupta / Andrea Fernandes / Laurie Elizabeth Kost / Sayantani B. Sindher / Wong Yu / Mindy Tsai / Robert Tibshirani / Scott D. Boyd / Manisha Desai / Holden T. Maecker / Stephen J. Galli / R. Sharon Chinthrajah / Rosemarie H. DeKruyff / Monali Manohar /
Kari C. Nadeau

Nature Communications, Vol 13, Iss 1, Pp 1-

2022  Volume 12

Abstract: Oral immunotherapy (OIT) clinical trials have helped a subset of participants achieve sustained unresponsiveness (SU) to the cognate allergen. Here the authors analyse immune cells from participants from one peanut OIT trial and show that CD8+ T cell ... ...

Abstract Oral immunotherapy (OIT) clinical trials have helped a subset of participants achieve sustained unresponsiveness (SU) to the cognate allergen. Here the authors analyse immune cells from participants from one peanut OIT trial and show that CD8+ T cell differentiation status at baseline may help to predict the likelihood of achieving SU.
Keywords Science ; Q
Language English
Publishing date 2022-11-01T00:00:00Z
Publisher Nature Portfolio
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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