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Article ; Online: [No title information]

Zaccaro, Lorenzo / Avondo, Stefano / Albani, Stefano / Scacciatella, Paolo

2024 Volume 73, Issue 2, Page(s) 101738

Abstract: Case summary: A 71-year-old presented at the outpatient clinic with palpitations and NYHA II functional class. 12-lead ECG exhibited Upper septal idiopathic left ventricular tachycardia (US-ILVT). Ventricular tachycardia (VT) was interrupted with ... ...

Title translation	A rare case of upper septal fascicular ventricular tachycardia presented in a case report.
Abstract	Case summary: A 71-year-old presented at the outpatient clinic with palpitations and NYHA II functional class. 12-lead ECG exhibited Upper septal idiopathic left ventricular tachycardia (US-ILVT). Ventricular tachycardia (VT) was interrupted with Verapamil administration, no further recurrences were documented after beta-blockers therapy was started. No coronary artery stenosis were detected. The US-ILVT was successfully treated by ablating the proximal site of the left anterior fascicle (LAF), where diastolic potential (P1) and pre-systolic potential (P2) with inverted sequence were detected during the electrophysiology study (EP) study. Cardiac magnetic resonance imaging (CMR) was performed with demonstration of intramyocardial late gadolinium enhancement (LGE) at the level of middle-basal portions of interventricular septum and basal portion of infero-lateral wall and no edema detection. A single catheter implantable cardioverter defibrillator (ICD) was implanted as secondary prevention. VT has never recurred during 3 months of follow-up with remote control of ICD. Discussion: To the best of our knowledge, this is the first report in which US-ILVT was associated with ventricular septal LGE, suggestive of previous myocarditis, as substrate of re-entrant circuit. Scar-related ventricular tachycardia circuit is also suggested by the evidence of a premature ventricular complex (PVC) as trigger of recurrent VT in our case.
MeSH term(s)	Humans ; Aged ; Contrast Media ; Gadolinium ; Tachycardia, Ventricular/etiology ; Tachycardia, Ventricular/therapy ; Tachycardia, Ventricular/diagnosis ; Magnetic Resonance Imaging/methods ; Cicatrix ; Catheter Ablation
Chemical Substances	Contrast Media ; Gadolinium (AU0V1LM3JT)
Language	French
Publishing date	2024-02-13
Publishing country	France
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	418425-7
ISSN	1768-3181 ; 0003-3928
ISSN (online)	1768-3181
ISSN	0003-3928
DOI	10.1016/j.ancard.2024.101738
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Article ; Online: Left atrial appendage closure device complicated by late-onset pericardial effusion and tamponade: a case report.

Albani, Stefano / Berlier, Nicola / Pisano, Francesco / Scacciatella, Paolo

European heart journal. Case reports

2021 Volume 5, Issue 3, Page(s) ytab058

Abstract: Background: Late-onset complications of left atrial appendage occlusion (LAAO) device procedure are anecdotal and there are no such complications reported in literature using Cardia Ultraseal (Cardia, Inc., Eagan, MN, USA).: Case summary: We report ... ...

Abstract	Background: Late-onset complications of left atrial appendage occlusion (LAAO) device procedure are anecdotal and there are no such complications reported in literature using Cardia Ultraseal (Cardia, Inc., Eagan, MN, USA). Case summary: We report the case of a 74-year-old Caucasian man affected by paroxysmal atrial fibrillation with significant bleeding risk (familiar thrombocytopenia, macroscopic haematuria episodes during therapy with direct oral anticoagulants, HAS-BLED risk score: 4) and ischaemic risk as well (CHADSVASC score: 3). The patient was treated with LAAO device implantation for high bleeding risk. Subsequently, after 26 days from LAAO procedure, he was admitted to the emergency department for haematic cardiac tamponade. The patient was successfully treated with subxyphoidal pericardiocentesis in the acute phase, unfortunately cardiac arrest occurred during the transfer to the referral hospital for urgent cardiac surgery. Permanent neurological damage was reported and the patient died on day 28. Discussion: LAAO late-onset complications are very rare and the case presented is the first case described of late-onset pericardial effusion and tamponade secondary to the Cardia Ultraseal LAAO device implantation. We present a revision of the literature regarding the occurrence of similar adverse events and discuss the hypothetical mechanism of this major complication.
Language	English
Publishing date	2021-02-28
Publishing country	England
Document type	Case Reports
ISSN	2514-2119
ISSN (online)	2514-2119
DOI	10.1093/ehjcr/ytab058
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Article ; Online: Incidental diagnosis of four pulmonary arteriovenous fistulas during patent foramen ovale closure: a case report.

Andreis, Alessandro / Agnoletti, Gabriella / Scacciatella, Paolo

Cardiology in the young

2020 Volume 30, Issue 9, Page(s) 1363–1365

Abstract: Cryptogenic cerebral ischemia in young patients is commonly ascribed to paradoxical embolism. We report the clinical case of a young patient with cryptogenic stroke and a patent foramen ovale, undergoing percutaneous closure of atrial septal defect. ... ...

Abstract	Cryptogenic cerebral ischemia in young patients is commonly ascribed to paradoxical embolism. We report the clinical case of a young patient with cryptogenic stroke and a patent foramen ovale, undergoing percutaneous closure of atrial septal defect. Contrast transoesophageal echocardiography at the end of the procedure demonstrated massive late residual right-to-left shunt, due to the coexistence of pulmonary arteriovenous fistulas that were subsequently closed. Routinary adoption of contrast transoesophageal echocardiography at the end of patent foramen ovale closure interventions may be useful to detect early and late residual shunts. Late residual shunts may be due to pulmonary fistulas, a well-known risk factor for recurrent thromboembolic events.
MeSH term(s)	Arteriovenous Fistula/diagnosis ; Arteriovenous Fistula/diagnostic imaging ; Echocardiography, Transesophageal ; Foramen Ovale, Patent/diagnosis ; Foramen Ovale, Patent/diagnostic imaging ; Heart Septal Defects, Atrial/diagnosis ; Heart Septal Defects, Atrial/diagnostic imaging ; Humans ; Pulmonary Artery/abnormalities ; Pulmonary Artery/diagnostic imaging ; Pulmonary Artery/surgery ; Pulmonary Veins/abnormalities ; Pulmonary Veins/diagnostic imaging ; Pulmonary Veins/surgery ; Stroke/diagnosis ; Stroke/etiology
Language	English
Publishing date	2020-07-27
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	1078466-4
ISSN	1467-1107 ; 1047-9511
ISSN (online)	1467-1107
ISSN	1047-9511
DOI	10.1017/S1047951120002152
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Article ; Online: Use of Taurolidine in a Patient With a Cardiac Implantable Electronic Device Protrusion.

Giudice, Marcello / Catuzzo, Bruna / Berlier, Nicola / Lau, Ernest W / Bonnemeier, Hendrik / Assadian, Ojan / Baldauf, Benito / Borov, Stefan / Scacciatella, Paolo

JACC. Case reports

2023 Volume 14, Page(s) 101835

Abstract: We report the successful salvage of cardiac implantable electronic device pulse generator protrusion sealed by the surrounding skin in a frail patient presenting 5 months after the last surgical revision. ( ...

Abstract	We report the successful salvage of cardiac implantable electronic device pulse generator protrusion sealed by the surrounding skin in a frail patient presenting 5 months after the last surgical revision. (
Language	English
Publishing date	2023-04-19
Publishing country	Netherlands
Document type	Case Reports
ISSN	2666-0849
ISSN (online)	2666-0849
DOI	10.1016/j.jaccas.2023.101835
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Article: Estimation of Aortic Stiffness with Bramwell-Hill Equation: A Comparative Analysis with Carotid-Femoral Pulse Wave Velocity.

Mesin, Luca / Floris, Luca / Policastro, Piero / Albani, Stefano / Scacciatella, Paolo / Pugliese, Nicola / Masi, Stefano / Grillo, Andrea / Fabris, Bruno / Antonini-Canterin, Francesco

Bioengineering (Basel, Switzerland)

2022 Volume 9, Issue 7

Abstract: Aortic stiffness is an important clinical parameter for predicting cardiovascular events. Carotid-femoral pulse wave velocity (cf-PWV) has been proposed for performing this evaluation non-invasively; however, it requires dedicated equipment and ... ...

Abstract	Aortic stiffness is an important clinical parameter for predicting cardiovascular events. Carotid-femoral pulse wave velocity (cf-PWV) has been proposed for performing this evaluation non-invasively; however, it requires dedicated equipment and experienced operators. We explored the possibility of measuring aortic stiffness using ultrasound scans of the abdominal aorta coupled with the Bramwell-Hill equation. Healthy subjects were investigated; measurements of cf-PWV were taken by arterial tonometry and aortic systo-diastolic pressure difference was estimated using a validated model. Pulsatility of an abdominal tract of aorta was assessed by automated processing of ultrasound scans. Through a Bland-Altmann analysis, we found large biases when estimating each parameter by applying the Bramwell-Hill equation to the measured values of the other two paramters (bias, ± 1.96 SD; PWV, about 2.1 ± 2.5 m/s; pulsatility, 12 ± 14%; pressure jump, 47 ± 55 mmHg). These results indicate that the two measures are not interchangeable, and that a large part of the bias is attributable to blood pressure estimation. Further studies are needed to identify the possible sources of bias between cf-PWV and aortic pulsatility.
Language	English
Publishing date	2022-06-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2746191-9
ISSN	2306-5354
ISSN	2306-5354
DOI	10.3390/bioengineering9070265
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Article ; Online: Anticoagulant and anti-thrombotic therapy in acute type B aortic dissection: when real-life scenarios face the shadows of the evidence-based medicine.

Bocchino, Pier Paolo / De Filippo, Ovidio / Piroli, Francesco / Scacciatella, Paolo / Imazio, Massimo / D'Ascenzo, Fabrizio / De Ferrari, Gaetano Maria

BMC cardiovascular disorders

2020 Volume 20, Issue 1, Page(s) 29

Abstract: Background: Evidence-based recommendations about anticoagulation in acute type B aortic dissection (TBAD) are completely missing, but there is a diffuse conviction that it could prevent the healing process of the dissected aorta's false lumen. However, ... ...

Abstract	Background: Evidence-based recommendations about anticoagulation in acute type B aortic dissection (TBAD) are completely missing, but there is a diffuse conviction that it could prevent the healing process of the dissected aorta's false lumen. However, several clinical conditions may lead to the necessity to start anticoagulant therapy among patients with acute type B aortic dissection, ranging from atrial fibrillation to more complicated clinical scenarios and the correct management in this kind of patients is still an open issue. Case presentation: We are presenting a 51-years-old man with multi-infarct encephalopathy referred to us for an acute TBAD and a first diagnosis of ischemic cardiomyopathy complicated by left ventricular (LV) thrombus formation. Coronary angiography revealed a critical stenosis of left anterior descending artery (LAD) treated with drug-eluting stent deployment. The patient was addressed to triple antithrombotic therapy with acetylsalicylic acid, clopidogrel and warfarin with target INR 2.0-2.5. After 6 months, computed tomography angiography revealed the stability of the dissection flap. Cardiac magnetic resonance imaging, however, confirmed the persistence of a small thrombotic formation in LV apex, thus double antithrombotic therapy with warfarin and clopidogrel was instituted. The patient remained asymptomatic during the follow-up period but was advised to suspend his job and physical activities. Conclusion: Current guidelines do not discuss anticoagulant therapy in the setting of TBAD and large randomized trials are lacking. Despite it is generally considered unsafe to administer anticoagulants in patients with TBAD, we present a case in which triple antithrombotic therapy was well tolerated and did not lead to progression of the intimal flap after 6 months.
MeSH term(s)	Aneurysm, Dissecting/complications ; Aneurysm, Dissecting/diagnostic imaging ; Anticoagulants/administration & dosage ; Anticoagulants/adverse effects ; Aortic Aneurysm, Thoracic/complications ; Aortic Aneurysm, Thoracic/diagnostic imaging ; Aspirin/administration & dosage ; Aspirin/adverse effects ; Clinical Decision-Making ; Clopidogrel/administration & dosage ; Clopidogrel/adverse effects ; Coronary Stenosis/complications ; Coronary Stenosis/diagnostic imaging ; Coronary Stenosis/therapy ; Disease Progression ; Drug-Eluting Stents ; Dual Anti-Platelet Therapy ; Fibrinolytic Agents/administration & dosage ; Fibrinolytic Agents/adverse effects ; Humans ; Male ; Middle Aged ; Percutaneous Coronary Intervention/adverse effects ; Percutaneous Coronary Intervention/instrumentation ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/adverse effects ; Risk Assessment ; Thrombosis/complications ; Thrombosis/diagnostic imaging ; Thrombosis/drug therapy ; Treatment Outcome ; Warfarin/administration & dosage ; Warfarin/adverse effects
Chemical Substances	Anticoagulants ; Fibrinolytic Agents ; Platelet Aggregation Inhibitors ; Warfarin (5Q7ZVV76EI) ; Clopidogrel (A74586SNO7) ; Aspirin (R16CO5Y76E)
Language	English
Publishing date	2020-01-23
Publishing country	England
Document type	Case Reports
ZDB-ID	2059859-2
ISSN	1471-2261 ; 1471-2261
ISSN (online)	1471-2261
ISSN	1471-2261
DOI	10.1186/s12872-020-01342-2
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Article ; Online: Iatrogenic erosion of the septum primum resulting in an atrial septal defect with left-to-right shunt: a rare pitfall of patent foramen ovale percutaneous closure.

Scacciatella, Paolo / Biava, Lorenza Michela / Marra, Sebastiano

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

2014 Volume 84, Issue 3, Page(s) 494–496

Abstract: Iatrogenic erosion of the septum primum after foramen ovale closure is an anecdotal event. We report the case of a 39-year-old woman admitted to our institution for multifocal cryptogenic cerebral ischemia and a patent foramen ovale (PFO) associated with ...

Abstract	Iatrogenic erosion of the septum primum after foramen ovale closure is an anecdotal event. We report the case of a 39-year-old woman admitted to our institution for multifocal cryptogenic cerebral ischemia and a patent foramen ovale (PFO) associated with an aneurysm of the septum primum. The patient underwent percutaneous closure of the PFO with an Amplatzer PFO Occluder device. At the 6-months follow up, the device was in the right position, but a jagged defect of the septum primum and evidence of significant left-to-right shunting was detected. The atrial septal defect was then repaired by a surgical approach. Although this event is not life-threatening, it should be considered as a therapeutic pitfall, resulting in a risk of paradoxical embolism recurrences and long-term hemodynamic impairment. © 2013 Wiley Periodicals, Inc.
MeSH term(s)	Adult ; Atrial Septum ; Cardiac Catheterization/methods ; Echocardiography, Transesophageal ; Female ; Foramen Ovale, Patent/diagnostic imaging ; Foramen Ovale, Patent/surgery ; Heart Septal Defects, Atrial/diagnosis ; Heart Septal Defects, Atrial/etiology ; Humans ; Iatrogenic Disease ; Septal Occluder Device/adverse effects
Language	English
Publishing date	2014-09-01
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1459995-8
ISSN	1522-726X ; 1522-1946
ISSN (online)	1522-726X
ISSN	1522-1946
DOI	10.1002/ccd.25333
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Article: Inferior Vena Cava Edge Tracking Echocardiography: A Promising Tool with Applications in Multiple Clinical Settings.

Albani, Stefano / Mesin, Luca / Roatta, Silvestro / De Luca, Antonio / Giannoni, Alberto / Stolfo, Davide / Biava, Lorenza / Bonino, Caterina / Contu, Laura / Pelloni, Elisa / Attena, Emilio / Russo, Vincenzo / Antonini-Canterin, Francesco / Pugliese, Nicola Riccardo / Gallone, Guglielmo / De Ferrari, Gaetano Maria / Sinagra, Gianfranco / Scacciatella, Paolo

Diagnostics (Basel, Switzerland)

2022 Volume 12, Issue 2

Abstract: Ultrasound (US)-based measurements of the inferior vena cava (IVC) diameter are widely used to estimate right atrial pressure (RAP) in a variety of clinical settings. However, the correlation with invasively measured RAP along with the reproducibility of ...

Abstract	Ultrasound (US)-based measurements of the inferior vena cava (IVC) diameter are widely used to estimate right atrial pressure (RAP) in a variety of clinical settings. However, the correlation with invasively measured RAP along with the reproducibility of US-based IVC measurements is modest at best. In the present manuscript, we discuss the limitations of the current technique to estimate RAP through IVC US assessment and present a new promising tool developed by our research group, the automated IVC edge-to-edge tracking system, which has the potential to improve RAP assessment by transforming the current categorical classification (low, normal, high RAP) in a continuous and precise RAP estimation technique. Finally, we critically evaluate all the clinical settings in which this new tool could improve current practice.
Language	English
Publishing date	2022-02-07
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics12020427
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Article ; Online: Never underestimate the comeback kid; a case report of very early side branch occlusion after Stentys Exposition implantation without kissing balloon.

Montefusco, Antonio / Scacciatella, Paolo / Omedè, Pierluigi / D'Ascenzo, Fabrizio / Gaita, Fiorenzo / Moretti, Claudio

International journal of cardiology

2016 Volume 215, Page(s) 502–503

MeSH term(s)	Aged ; Angioplasty, Balloon/methods ; Coronary Angiography ; Female ; Humans ; Non-ST Elevated Myocardial Infarction/diagnostic imaging ; Non-ST Elevated Myocardial Infarction/therapy ; Treatment Outcome
Language	English
Publishing date	2016-07-15
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2016.04.057
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Article ; Online: Impact of chronic kidney disease on mortality in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention. A long-term single-center mortality study.

Peyracchia, Mattia / Scacciatella, Paolo / Conrotto, Federico / Meynet, Ilaria / Biava, Lorenza M / Budano, Carlo / Pennone, Mauro / D'Amico, Maurizio / Gaita, Fiorenzo

Minerva cardioangiologica

2018 Volume 66, Issue 1, Page(s) 6–15

Abstract: Background: Chronic kidney disease (CKD) is associated with increased risk of mortality. We examined the impact of moderate and severe CKD at presentation on short- and long-term mortality among unselected patients with ST-segment elevation myocardial ... ...

Abstract	Background: Chronic kidney disease (CKD) is associated with increased risk of mortality. We examined the impact of moderate and severe CKD at presentation on short- and long-term mortality among unselected patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI). Methods: The study cohort consists of 501 patients (pts), enrolled from October 2005 to December 2012. The median follow-up was 46.52±25.58 months (range 8-99). A severe CKD (estimated Glomerular Filtration Rate [eGFR] <30 mL/min/1.73 m2) was detected in 16 pts (3.19%), a moderate CKD (eGFR 30-59 mL/min/1.73 m2) in 110 (21.96%) and a normal kidney function (eGFR >60 mL/min/1.73 m2) in 375 (74.85%). Results: The crude in-hospital mortality rate resulted significantly higher in pts with severe and moderate CKD compared to pts with normal renal function (50% and 19.08% versus 2.93%, P<0.0001), as well as the long-term mortality rate (57.14% and 46.34% versus 8.77%, P<0.0001). After adjustment for confounding variables, severe and moderate CKD resulted the main independent predictors of in-hospital (odds ratio [OR]=21.815, P<0.0001 for severe CKD and OR= 4.203, P=0.002 for moderate CKD) and long-term (hazard ratio [HR]= 5.272, P=0.001; HR= 1.978, P=0.006) mortality. Conclusions: CKD is a frequent condition in patients with STEMI treated with PPCI and it is associated to an excess of mortality, resulting the main independent negative prognostic predictor.
MeSH term(s)	Aged ; Cohort Studies ; Female ; Follow-Up Studies ; Glomerular Filtration Rate ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Percutaneous Coronary Intervention/methods ; Prognosis ; Prospective Studies ; Renal Insufficiency, Chronic/mortality ; Renal Insufficiency, Chronic/physiopathology ; ST Elevation Myocardial Infarction/mortality ; ST Elevation Myocardial Infarction/therapy ; Severity of Illness Index ; Time Factors
Language	English
Publishing date	2018-02
Publishing country	Italy
Document type	Journal Article
ZDB-ID	123583-7
ISSN	1827-1618 ; 0026-4725
ISSN (online)	1827-1618
ISSN	0026-4725
DOI	10.23736/S0026-4725.17.04506-6
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