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  1. Article ; Online: COVID-19 and head and neck cancer management. Experience of an oncological hub comprehensive cancer centre and literature review.

    Chu, Francesco / Zocchi, Jacopo / De Berardinis, Rita / Bandi, Francesco / Pietrobon, Giacomo / Scaglione, Donatella / Radice, Davide / Tagliabue, Marta / Ansarin, Mohssen

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2022  Volume 42, Issue Suppl. 1, Page(s) S79–S86

    MeSH term(s) COVID-19 ; Head and Neck Neoplasms/therapy ; Humans
    Language English
    Publishing date 2022-06-28
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-suppl.1-42-2022-09
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2608: Show issues Location:
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  2. Article ; Online: Oral tongue carcinoma: prognostic changes according to the updated 2020 version of the AJCC/UICC TNM staging system.

    Tagliabue, Marta / De Berardinis, Rita / Belloni, Pietro / Gandini, Sara / Scaglione, Donatella / Maffini, Fausto / Mirabella, Rosolino Antonino / Riccio, Stefano / Gioacchino, Giugliano / Bruschini, Roberto / Chu, Francesco / Ansarin, Mohssen

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2022  Volume 42, Issue 2, Page(s) 140–149

    Abstract: Background: This study aimed to evaluate the performance of the 2017 8: Materials and methods: The cohort involved 300 patients affected by OTSCC treated with surgery. All cases were classified according to the 7: Results: According to the 7: ... ...

    Abstract Background: This study aimed to evaluate the performance of the 2017 8
    Materials and methods: The cohort involved 300 patients affected by OTSCC treated with surgery. All cases were classified according to the 7
    Results: According to the 7
    Conclusions: This study confirmed that the recent update of the 8th edition of the TNM (2020) improves stratification and identification of advanced tumours, reducing the number of T3 compared to the 2017 edition and increasing the number of patients with pT4. This improvement made by the updated edition may reduce the risk of skipping adjuvant therapy.
    MeSH term(s) Carcinoma, Squamous Cell/pathology ; Head and Neck Neoplasms/pathology ; Humans ; Mouth Neoplasms/pathology ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging ; Prognosis ; Retrospective Studies ; Squamous Cell Carcinoma of Head and Neck/pathology ; Tongue ; Tongue Neoplasms/pathology ; Tongue Neoplasms/surgery
    Language English
    Publishing date 2022-05-24
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-N2055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2608: Show issues Location:
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  3. Article ; Online: Tongue cancer treatment and oncological outcomes: The role of glossectomy classification.

    De Berardinis, Rita / Tagliabue, Marta / Belloni, Pietro / Gandini, Sara / Scaglione, Donatella / Maffini, Fausto / Margherini, Stefano / Riccio, Stefano / Giugliano, Gioacchino / Bruschini, Roberto / Chu, Francesco / Ansarin, Mohssen

    Surgical oncology

    2022  Volume 42, Page(s) 101751

    Abstract: Background: Nowadays surgery remains the gold standard of treatment for tongue cancer. Via a more clear and precise terminology, the glossectomy classification by Ansarin et al. facilitates shared communication between surgeons, allowing comparison ... ...

    Abstract Background: Nowadays surgery remains the gold standard of treatment for tongue cancer. Via a more clear and precise terminology, the glossectomy classification by Ansarin et al. facilitates shared communication between surgeons, allowing comparison between published research and improving surgical practice and patient care. To establish the association of glossectomies, according to their classification by Ansarin et al. with overall survival (OS), disease-free survival (DSF), and cause-specific survival (CSS) in tongue cancer, we conducted a systemic retrospective study on 300 consecutive patients affected by primary oral tongue cancer and treated with surgery at the European Institute of Oncology, IRCCS (IEO).
    Methods: Three hundred patients with tongue squamous cell carcinoma and treated at the Division of Otorhinolaryngology and Head and Neck Surgery of the European Institute of Oncology, IRCCS were cataloged according to the glossectomy classification. OS, DFS, and CSS were compared by surgical treatments.
    Results: OS-5yrs was 80% for the type I glossectomy group, 75% for type II, 65% for type III, and 35% for type IV-V. DFS-5yrs was 74%, 60%, 55%, and 27%, respectively for I, II, III, and IV-V glossectomy group; CSS-5yrs was 82%, 80%, 72%, and 48%, respectively for I, II, III, and IV-V glossectomy group (p < 0.01).
    Conclusions: This study confirmed that the application of the glossectomy classification was statistically correlated with patients' oncological outcomes.
    MeSH term(s) Carcinoma, Squamous Cell/pathology ; Glossectomy ; Humans ; Retrospective Studies ; Tongue/pathology ; Tongue Neoplasms/pathology ; Tongue Neoplasms/surgery
    Language English
    Publishing date 2022-04-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1107810-8
    ISSN 1879-3320 ; 0960-7404
    ISSN (online) 1879-3320
    ISSN 0960-7404
    DOI 10.1016/j.suronc.2022.101751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3409: Show issues Location:
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  4. Article ; Online: Total thyroidectomy versus lobectomy: surgical approach to T1-T2 papillary thyroid cancer.

    Di Filippo, Luigi / Giugliano, Gioacchino / Tagliabue, Marta / Gandini, Sara / Sileo, Federica / Allora, Agnese / Grosso, Enrica / Proh, Michele / Basso, Veronica / Scaglione, Donatella / Manzoni, Marco Federico / Ansarin, Mohssen

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2021  Volume 40, Issue 4, Page(s) 254–261

    MeSH term(s) Carcinoma, Papillary/surgery ; Humans ; Neck Dissection ; Neoplasm Recurrence, Local/surgery ; Retrospective Studies ; Thyroid Cancer, Papillary/surgery ; Thyroid Neoplasms/surgery ; Thyroidectomy
    Language English
    Publishing date 2021-05-27
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-N0608
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2608: Show issues Location:
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  5. Article: Survival Outcomes in Oral Tongue Cancer: A Mono-Institutional Experience Focusing on Age.

    Ansarin, Mohssen / De Berardinis, Rita / Corso, Federica / Giugliano, Gioacchino / Bruschini, Roberto / De Benedetto, Luigi / Zorzi, Stefano / Maffini, Fausto / Sovardi, Fabio / Pigni, Carolina / Scaglione, Donatella / Alterio, Daniela / Cossu Rocca, Maria / Chiocca, Susanna / Gandini, Sara / Tagliabue, Marta

    Frontiers in oncology

    2021  Volume 11, Page(s) 616653

    Abstract: Objective: The prognostic role of age among patients affected by Oral Tongue Squamous Cell Carcinoma (OTSCC) is a topic of debate. Recent cohort studies have found that patients diagnosed at 40 years of age or younger have a better prognosis. The aim of ...

    Abstract Objective: The prognostic role of age among patients affected by Oral Tongue Squamous Cell Carcinoma (OTSCC) is a topic of debate. Recent cohort studies have found that patients diagnosed at 40 years of age or younger have a better prognosis. The aim of this cohort study was to clarify whether age is an independent prognostic factor and discuss heterogeneity of outcomes by stage and treatments in different age groups.
    Methods: We performed a study on 577 consecutive patients affected by primary tongue cancer and treated with surgery and adjuvant therapy according to stage, at European Institute of Oncology, IRCCS. Patients with age at diagnosis below 40 years totaled 109 (19%). Overall survival (OS), disease-free survival (DFS), tongue specific free survival (TSFS) and cause-specific survival (CSS) were compared by age groups. Multivariate Cox proportional hazards models were used to assess the independent role of age.
    Results: The median follow-up time was 5.01 years (range 0-18.68) years with follow-up recorded up to February 2020. After adjustment for all the significant confounding and prognostic factors, age remained independently associated with OS and DSF (respectively, p = 0.002 and p = 0.02). In CSS and TSFS curves, the role of age seems less evident (respectively, p = 0.14 and p = 0.0.37). In the advanced stage sub-group (stages III-IV), age was significantly associated with OS and CSS with almost double increased risk of dying (OS) and dying from tongue cancer (CSS) in elderly compared to younger groups (OS: HR = 2.16 95%, CI: 1.33-3.51, p= 0.001; CSS: HR = 1.76 95%, CI: 1.03-3.01, p = 0.02, respectively). In our study, young patients were more likely to be treated with intensified therapies (glossectomies types III-V and adjuvant radio-chemotherapy). Age was found as a prognostic factor, independently of other significant factors and treatment. Also the T-N tract involved by disease and neutrophil-to-lymphocyte ratio ≥3 were independent prognostic factors.
    Conclusions: Young age at diagnosis is associated with a better overall survival. Fewer younger people than older people died from tongue cancer in advanced stages.
    Language English
    Publishing date 2021-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2021.616653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Continuity of Cancer Care: The Surgical Experience of Two Large Cancer Hubs in London and Milan.

    Monroy-Iglesias, Maria J / Tagliabue, Marta / Dickinson, Harvey / Roberts, Graham / De Berardinis, Rita / Russell, Beth / Moss, Charlotte / Irwin, Sophie / Olsburgh, Jonathon / Cocco, Ivana Maria Francesca / Schizas, Alexis / McCrindle, Sarah / Nath, Rahul / Brunet, Aina / Simo, Ricard / Tornari, Chrysostomos / Srinivasan, Parthi / Prachalias, Andreas / Davies, Andrew /
    Geh, Jenny / Fraser, Stephanie / Routledge, Tom / Ma, RuJun / Doerge, Ella / Challacombe, Ben / Nair, Raj / Hadjipavlou, Marios / Scarpinata, Rosaria / Sorelli, Paolo / Dolly, Saoirse / Mistretta, Francesco Alessandro / Musi, Gennaro / Casiraghi, Monica / Aloisi, Alessia / Dell'Acqua, Andrea / Scaglione, Donatella / Zanoni, Stefania / Rampazio Da Silva, Daniele / Brambilla, Daniela / Bertolotti, Raffaella / Peruzzotti, Giulia / Maggioni, Angelo / de Cobelli, Ottavio / Spaggiari, Lorenzo / Ansarin, Mohssen / Mastrilli, Fabrizio / Gandini, Sara / Jain, Urvashi / Hamed, Hisham / Haire, Kate / Van Hemelrijck, Mieke

    Cancers

    2021  Volume 13, Issue 7

    Abstract: The SARS-CoV-2 (COVID-19) pandemic is having a large effect on the management of cancer patients. This study reports on the approach and outcomes of cancer patients receiving radical surgery with curative intent between March and September 2020 (in ... ...

    Abstract The SARS-CoV-2 (COVID-19) pandemic is having a large effect on the management of cancer patients. This study reports on the approach and outcomes of cancer patients receiving radical surgery with curative intent between March and September 2020 (in comparison to 2019) in the European Institute of Oncology, IRCCS (IEO) in Milan and the South East London Cancer Alliance (SELCA). Both institutions implemented a COVID-19 minimal pathway where patients were required to self-isolate prior to admission and were swabbed for COVID-19 within 72 h of surgery. Positive patients had surgery deferred until a negative swab. At IEO, radical surgeries declined by 6% as compared to the same period in 2019 (
    Language English
    Publishing date 2021-03-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13071597
    Database MEDical Literature Analysis and Retrieval System OnLINE

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