Article ; Online: Efficacy of a new nutraceutical formulation: L-tryptophan, probiotics, charcoal, chamomile, mint, and licorice (COLONIR®) in the improvement of gastrointestinal symptoms in subjects with irritable bowel syndrome.
2023 Volume 69, Issue 1, Page(s) 123–127
Abstract: Background: Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders. IBS is characterized by recurrent chronic abdominal pain and altered bowel habits in the absence of organic damage. Although there are reviews ... ...
| Abstract | Background: Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders. IBS is characterized by recurrent chronic abdominal pain and altered bowel habits in the absence of organic damage. Although there are reviews and guidelines for treating IBS, the complexity and diversity of IBS presentation make treatment difficult. Treatment of IBS focuses on relieving symptoms as mild signs and symptoms can often be controlled by managing stress and by making changes in diet and lifestyle. The use of nutraceutical compounds has been advocated as a possible alternative treatment in patients with IBS. COLONIR Methods: An initial cohort of 1004 consecutive patients referred to 25 different Units of Internal Medicine a/o Gastroenterology in Italy to perform colonoscopy for intestinal symptoms was asked to participate. Patients were treated for 2 months with two doses of nutraceuticals/day during meals namely COLONIR Results: After 2 months, 899 patients completed the follow-up. COLONIR Conclusions: These promising results, here reported, need to be confirmed, valuating the efficacy of COLONIR |
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| MeSH term(s) | Humans ; Irritable Bowel Syndrome/complications ; Irritable Bowel Syndrome/drug therapy ; Charcoal ; Tryptophan ; Chamomile ; Glycyrrhiza ; Mentha ; Dietary Supplements ; Gastrointestinal Diseases ; Probiotics ; Abdominal Pain/drug therapy ; Abdominal Pain/etiology ; Flower Essences ; Chronic Pain |
| Chemical Substances | Charcoal (16291-96-6) ; Tryptophan (8DUH1N11BX) ; Flower Essences |
| Language | English |
| Publishing date | 2023-03-01 |
| Publishing country | Italy |
| Document type | Journal Article |
| ZDB-ID | 3062713-8 |
| ISSN | 2724-5365 |
| ISSN (online) | 2724-5365 |
| DOI | 10.23736/S2724-5985.22.03282-X |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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