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  1. Article ; Online: Scientific divisions on covid-19: time for open debate.

    Scanlon, Thomas

    BMJ (Clinical research ed.)

    2020  Volume 371, Page(s) m4538

    Language English
    Publishing date 2020-11-25
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m4538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: All together now.

    Scanlon, Thomas

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2020  Volume 70, Issue 692, Page(s) 130

    MeSH term(s) Family Practice/organization & administration ; Humans ; United Kingdom
    Language English
    Publishing date 2020-02-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp20X708617
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: You say Freiberg.

    Scanlon, Tom

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2019  Volume 69, Issue 685, Page(s) 397

    MeSH term(s) General Practitioners ; Humans ; Metatarsus/abnormalities ; Osteochondritis/congenital ; Osteochondritis/diagnosis ; Rare Diseases/diagnosis ; Referral and Consultation
    Language English
    Publishing date 2019-07-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp19X704849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Determination of output factor for CyberKnife using scintillation dosimetry and deep learning.

    Ocampo, Jeremy / Heyes, Geoff / Dehghani, Hamid / Scanlon, Tim / Jolly, Simon / Gibson, Adam

    Physics in medicine and biology

    2024  Volume 69, Issue 2

    Abstract: ... ...

    Abstract Objective
    MeSH term(s) Deep Learning ; Radiometry/methods ; Radiosurgery/methods ; Algorithms ; Neural Networks, Computer
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/1361-6560/ad1b69
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Algorithm for finding new identifiable reparametrizations of parametric ODEs

    Meshkat, Nicolette / Ovchinnikov, Alexey / Scanlon, Thomas

    2023  

    Abstract: Structural identifiability concerns the question of which unknown parameters of a model can be recovered from (perfect) input-output data. If all of the parameters of a model can be recovered from data, the model is said to be identifiable. However, in ... ...

    Abstract Structural identifiability concerns the question of which unknown parameters of a model can be recovered from (perfect) input-output data. If all of the parameters of a model can be recovered from data, the model is said to be identifiable. However, in many models, there are parameters that can take on an infinite number of values but yield the same input-output data. In this case, those parameters and the model are called unidentifiable. The question is then what to do with an unidentifiable model. One can either adjust the model, if experimentally feasible, or try to find a reparametrization to make the model identifiable. In this paper, we take the latter approach. While existing approaches to find identifiable reparametrizations were limited to scaling reparametrizations or were not guaranteed to find an identifiable reparametrization, we show in this paper that there always exists a locally identifiable model with the same input-output behavior as the original one. We also prove that, for linear models, a globally identifiable reparametrization always exists and show that, for a certain class of linear compartmental models, an explicit reparametrization formula exists. We illustrate our method on several examples and provide detailed analysis in supplementary material on github.

    Comment: corrected abstract
    Keywords Electrical Engineering and Systems Science - Systems and Control ; Mathematics - Algebraic Geometry ; Mathematics - Dynamical Systems ; Quantitative Biology - Quantitative Methods ; 92B05 ; 93C15 ; 93B25 ; 93B30 ; 34A55 ; 12H05 ; 03C40 ; 03C60
    Subject code 004
    Publishing date 2023-10-04
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Kamm on the disvalue of death.

    Scanlon, T M

    Journal of medical ethics

    2015  Volume 41, Issue 6, Page(s) 490

    MeSH term(s) Bioethical Issues ; Books ; Humans ; Moral Obligations
    Language English
    Publishing date 2015-06
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 194927-5
    ISSN 1473-4257 ; 0306-6800
    ISSN (online) 1473-4257
    ISSN 0306-6800
    DOI 10.1136/medethics-2014-102037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Systematic Review of RCTs Assessing the Effectiveness of mHealth Interventions to Improve Statin Medication Adherence: Using the Behaviour-Change Technique Taxonomy to Identify the Techniques That Improve Adherence.

    Bond, Zoe / Scanlon, Tanya / Judah, Gaby

    Healthcare (Basel, Switzerland)

    2021  Volume 9, Issue 10

    Abstract: Statin non-adherence is a common problem in the management of cardiovascular disease (CVD), increasing patient morbidity and mortality. Mobile health (mHealth) interventions may be a scalable way to improve medication adherence. The objectives of this ... ...

    Abstract Statin non-adherence is a common problem in the management of cardiovascular disease (CVD), increasing patient morbidity and mortality. Mobile health (mHealth) interventions may be a scalable way to improve medication adherence. The objectives of this review were to assess the literature testing mHealth interventions for statin adherence and to identify the Behaviour-Change Techniques (BCTs) employed by effective and ineffective interventions. A systematic search was conducted of randomised controlled trials (RCTs) measuring the effectiveness of mHealth interventions to improve statin adherence against standard of care in those who had been prescribed statins for the primary or secondary prevention of CVD, published in English (1 January 2000-17 July 2020). For included studies, relevant data were extracted, the BCTs used in the trial arms were coded, and a quality assessment made using the Risk of Bias 2 (RoB2) questionnaire. The search identified 17 relevant studies. Twelve studies demonstrated a significant improvement in adherence in the mHealth intervention trial arm, and five reported no impact on adherence. Automated phone messages were the mHealth delivery method most frequently used in effective interventions. Studies including more BCTs were more effective. The BCTs most frequently associated with effective interventions were "Goal setting (behaviour)", "Instruction on how to perform a behaviour", and "Credible source". Other effective techniques were "Information about health consequences", "Feedback on behaviour", and "Social support (unspecified)". This review found moderate, positive evidence of the effect of mHealth interventions on statin adherence. There are four primary recommendations for practitioners using mHealth interventions to improve statin adherence: use multifaceted interventions using multiple BCTs, consider automated messages as a digital delivery method from a credible source, provide instructions on taking statins, and set adherence goals with patients. Further research should assess the optimal frequency of intervention delivery and investigate the generalisability of these interventions across settings and demographics.
    Language English
    Publishing date 2021-09-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare9101282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Effective weed management from theory to reality

    Scanlon, Tim

    Plant protection quarterly

    2015  Volume 30, Issue 3, Page(s) 76

    Document type Article
    ZDB-ID 848198-2
    ISSN 0815-2195
    Database Current Contents Nutrition, Environment, Agriculture

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  9. Article: A Curious Case of Cough in a Young Woman

    Di Giovanni, B / Newmarch, W / Weiler, M / Casserly, B / Scanlon, T

    Irish medical journal

    2019  Volume 112, Issue 4, Page(s) 920

    Abstract: Inflammatory myofibroblastic tumour (IMT) is a rare neoplasm derived from tissue of mesenchymal origin. This tumour occurs predominantly in the lung, though extrapulmonary sites have been documented throughout the body.1 Presentation can be variable ... ...

    Abstract Inflammatory myofibroblastic tumour (IMT) is a rare neoplasm derived from tissue of mesenchymal origin. This tumour occurs predominantly in the lung, though extrapulmonary sites have been documented throughout the body.1 Presentation can be variable depending on location of the tumour and can include constitutional symptoms (fever, weight loss), thrombocytosis, hypergammaglobulinemia, anemia, and mass effect on local structures.2 Majority of patients with intrapulmonary IMT remain asymptomatic but can have symptoms including chest pain, dyspnoea, cough or haemoptysis.3 Most cases of IMT present in younger individuals (under age 40).4 Although the aetiology of IMT is unclear, current hypotheses suggest an inflammatory response to infection or an underlying malignancy could promote such cellular changes. Alternatively, the inflammatory component itself may be a consequence of the development of these mesenchymal tumours.
    MeSH term(s) Adult ; Cough/etiology ; Female ; Humans ; Plasma Cell Granuloma, Pulmonary/complications ; Plasma Cell Granuloma, Pulmonary/diagnostic imaging ; Plasma Cell Granuloma, Pulmonary/pathology ; Plasma Cell Granuloma, Pulmonary/surgery ; Tomography, X-Ray Computed
    Language English
    Publishing date 2019-04-11
    Publishing country Ireland
    Document type Case Reports
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Transjugular intrahepatic portosystemic shunt (TIPS) procedure: an assessment of the quality and readability of online information.

    Lim, Sean-Tee J M / Kelly, Martin / Selvarajah, Logeswaran / Murray, Michael / Scanlon, Timothy

    BMC medical informatics and decision making

    2021  Volume 21, Issue 1, Page(s) 149

    Abstract: Purpose: Transjugular intrahepatic portosystemic shunt (TIPS) procedure is an established procedure carried out by interventional radiologists to achieve portal decompression and to manage the complications of portal hypertension. The aim of this study ... ...

    Abstract Purpose: Transjugular intrahepatic portosystemic shunt (TIPS) procedure is an established procedure carried out by interventional radiologists to achieve portal decompression and to manage the complications of portal hypertension. The aim of this study was to evaluate the quality and readability of information available online for TIPS procedure.
    Methods: Websites were identified using the search terms "TIPS procedure", "TIPSS procedure", "transjugular intrahepatic portosystemic shunt procedure", with the first 25 pages from the three most popular search engines (Google, Bing and Yahoo) being selected for evaluation with a total of 225. Each Website was grouped by authorship into one of five categories: (1) Physician, (2) Academic, (3) For-profit, (4) Non-profit (including government and public health), or (5) Other (discussion/social media). Readability of each Website was assessed using the Flesch-Reading Ease score, Flesch-Kincaid grade level, Gunning-Fog Index, Coleman-Liau and SMOG index. Quality was calculated using the DISCERN instrument, the Journal of the American Medical Association (JAMA) benchmark criteria and the presence of Health on the Net (HON) code certification.
    Results: After disregarding duplicate and non-accessible Websites a total of 81 were included. The mean DISCERN score assessing the quality of information provided by Websites was "good" (59.3 ± 10.2) with adherence to the JAMA Benchmark being 54.3%. Websites with HON-code certification were statistically significantly higher in terms of DISCERN (p = 0.034) and JAMA scores (p = 0.003) compared to HON-code negative sites. The readability scores of Websites ranged from 10 to 12th grade across calculators. Thirty-two out of the 81 Websites were targeted towards patients (39.5%), 46 towards medical professionals (56.8%) and 3 were aimed at neither (3.7%). The medical professional aimed Websites were statistically significantly more difficulty to read across all readability formulas (all p < 0.001).
    Conclusion: While quality of online information available to patients is "good", the average readability for information on the internet for TIPS is set far above the recommended 7th-grade level. Academic Websites were of the highest quality, yet most challenging for the general public to read. These findings call for the production of high-quality and comprehensible content around TIPS procedure, where physicians can reliably direct their patients for information.
    MeSH term(s) Benchmarking ; Comprehension ; Consumer Health Information ; Humans ; Internet ; Portasystemic Shunt, Transjugular Intrahepatic ; Reading
    Language English
    Publishing date 2021-05-05
    Publishing country England
    Document type Journal Article
    ISSN 1472-6947
    ISSN (online) 1472-6947
    DOI 10.1186/s12911-021-01513-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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