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  1. Book ; Thesis: Modulation humoraler Parameter durch Laserakupunktur am Beispiel der Migränetherapie

    Schütz, Hendrik

    1999  

    Author's details vorgelegt von Hendrik Schütz
    Language German
    Size 49 Bl. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Kiel, Univ., Diss., 1999
    HBZ-ID HT011156028
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    99 D 2570 order for loan Magazin

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  2. Book: Screening von Drogen und Arzneimitteln mit Immunoassays

    Schütz, Harald

    1999  

    Author's details Harald Schütz
    Keywords Rauschgift ; Immunassay ; Arzneimittel
    Subject Immunoassay ; Fertigarzneimittel ; Therapeutikum ; Medikament ; Medukamente ; Pharmakon ; Pharmaka ; Arzneistoff ; Arzneimittelwirkstoff ; Arznei ; Pharmazeutikum ; Pharmazeutika ; Pharmazeutischer Wirkstoff ; Arzneidroge ; Narkotisches Genussmittel ; Rauschdroge ; Rauschmittel ; Suchtgift ; Suchtmittel ; Psychoaktive Substanz ; Droge ; Drogen ; Rauschgifte ; Rauschdrogen
    Language German
    Size X, 292 S. : graph. Darst.
    Edition 3., überarb. und erw. Aufl.
    Publisher Wiss. Verl.-Abt. Abbott GmbH
    Publishing place Wiesbaden
    Document type Book
    HBZ-ID HT010183642
    ISBN 3-926035-65-X ; 978-3-926035-65-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1999 A 2464 order for loan Magazin

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  3. Article: (Kein) Kausalzusammenhang zwischen Weiterbildungsassistenz und einer Praxis- Vergrößerung bzw. einem übergroßen Praxisumfang (LSG Berlin-Brandenburg, Urt. v. 9.5.2018 - L 7 KA 76/14) m. Anm. Jan Harald Schütz

    Schütz, Harald

    Gesundheitsrecht

    2019  Volume 18, Issue 3, Page(s) 172

    Language German
    Document type Article
    ZDB-ID 2092255-3
    ISSN 1610-1197
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6441: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Book: Forensic medicine

    Dettmeyer, Reinhard / Verhoff, Marcel A. / Schütz, Harald

    fundamentals and perspectives

    2014  

    Author's details Reinhard B. Dettmeyer ; Marcel A. Verhoff ; Harald F. Schutz
    Keywords Medical jurisprudence ; Rechtsmedizin
    Subject Forensische Medizin ; Gerichtliche Medizin ; Gerichtsmedizin
    Subject code 614.1
    Language English
    Size XXIV, 584 S. : zahlr. Ill., graph. Darst., 26 cm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017903131
    ISBN 978-3-642-38817-0 ; 9783642388187 ; 3-642-38817-5 ; 3642388183
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 3684 available for loan (reading room) Lesesaal EG

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  5. Book: Rechtsmedizin

    Dettmeyer, Reinhard / Schütz, Harald / Verhoff, Marcel A.

    (Springer-Lehrbuch)

    2014  

    Author's details R. B. Dettmeyer ; H. F. Schütz ; M. A. Verhoff
    Series title Springer-Lehrbuch
    Keywords Rechtsmedizin
    Subject Forensische Medizin ; Gerichtliche Medizin ; Gerichtsmedizin
    Language German
    Size XI, 309 S. : Ill., graph. Darst., 240 mm x 168 mm
    Edition 2., aktualisierte Aufl.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018324440
    ISBN 978-3-642-55021-8 ; 3-642-55021-5 ; 9783642550225 ; 3642550223
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    W 700 S 3 on loan 0 Vormerkungen
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    W 700 S 3 available for loan (reading room) Lesesaal EG Lehrbuchsammlung
    2009 A 9902 order for loan Magazin
    2014 A 3711 available for loan (reading room) Lesesaal EG

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  6. Article: Clinical experience with Sanalepsi Russi.

    SCHUETZ, H

    Praxis

    2010  Volume 36, Issue 7, Page(s) 109–111

    Title translation Klinische Erfahrungen mit Sanalepsi Russi.
    MeSH term(s) Humans
    Language German
    Publishing date 2010-02-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 209026-0
    ISSN 1661-8165 ; 0369-8394 ; 1661-8157
    ISSN (online) 1661-8165
    ISSN 0369-8394 ; 1661-8157
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.118: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 12: Show issues

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  7. Article ; Online: Critical Remarks on Reference-Scaled Average Bioequivalence.

    Schütz, Helmut / Labes, Detlew / Wolfsegger, Martin J

    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques

    2022  Volume 25, Page(s) 285–296

    Abstract: Purpose: More than a decade ago the option to assess highly variable drugs / drug products by reference-scaled average bioequivalence was introduced in regulatory practice. Recommended approaches differ between jurisdictions and may lead to different ... ...

    Abstract Purpose: More than a decade ago the option to assess highly variable drugs / drug products by reference-scaled average bioequivalence was introduced in regulatory practice. Recommended approaches differ between jurisdictions and may lead to different conclusions even for the same data set. According to our knowledge, implemented methods have not been directly compared for their operating characteristics (Type I Error and power).
    Methods: We performed Monte Carlo simulations to assess the consumer risk and the clinically relevant difference for the recommended regulatory settings.
    Results: In all methods for reference-scaled average bioequivalence the Type I Error can be inflated with a consequently compromised consumer risk. Furthermore, the clinically relevant difference could vary between studies performed with the same reference product.
    Conclusions: Only average bioequivalence with fixed - widened - limits would both maintain the consumer risk and offer an unambiguously defined clinically not relevant difference. As long as such an approach is not implemented in regulatory practice, we recommend adjusting the level of the test a.
    MeSH term(s) Therapeutic Equivalency
    Language English
    Publishing date 2022-09-16
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1422972-9
    ISSN 1482-1826 ; 1482-1826
    ISSN (online) 1482-1826
    ISSN 1482-1826
    DOI 10.18433/jpps32892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Two-stage designs in bioequivalence trials.

    Schütz, Helmut

    European journal of clinical pharmacology

    2015  Volume 71, Issue 3, Page(s) 271–281

    Abstract: Purpose: The aim of this study is to assess the current status of non-fixed sample size designs in bioequivalence trials with a focus on two-stage adaptive approaches.: Methods: We searched PubMed and Google Scholar from inception to October 2014. ... ...

    Abstract Purpose: The aim of this study is to assess the current status of non-fixed sample size designs in bioequivalence trials with a focus on two-stage adaptive approaches.
    Methods: We searched PubMed and Google Scholar from inception to October 2014. Regulatory guidelines were obtained from the public domain. Different methods were compared by Monte Carlo simulations for their impact on the patient's and producer's risks.
    Results: Add-on designs, group sequential designs and adaptive two-stage sequential designs are currently accepted to demonstrate bioequivalence in various regulations. All three approaches may inflate the patient's risk if applied inconsiderately. Direct transfer of methods developed for superiority testing to bioequivalence is not warranted. Published two-stage frameworks maintain the type I error and generally the desired power. Adaptation based on the observed T/R ratio observed in the first stage should be applied with caution. Monte Carlo simulations are an efficient tool to explore the operating characteristics of methods.
    Conclusions: Validated two-stage frameworks can be applied without requiring the sponsor to perform own simulations-which could further improve power based on additional assumptions. Two-stage designs are both ethical and economical alternatives to fixed sample designs.
    MeSH term(s) Clinical Trials as Topic/methods ; Government Regulation ; Humans ; Monte Carlo Method ; Research Design ; Sample Size ; Therapeutic Equivalency
    Language English
    Publishing date 2015-03
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 121960-1
    ISSN 1432-1041 ; 0031-6970
    ISSN (online) 1432-1041
    ISSN 0031-6970
    DOI 10.1007/s00228-015-1806-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 672: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book ; Thesis: Gesundheitsfürsorge zwischen humanitärem Anspruch und eugenischer Verpflichtung

    Schütz, Horst

    Entwicklung und Kontinuität sozialhygienischer Anschauungen zwischen 1920 und 1960 am Beispiel von Prof. Dr. Carl Coerper

    (Abhandlungen zur Geschichte der Medizin und der Naturwissenschaften ; 98)

    2004  

    Author's details von Horst Schütz
    Series title Abhandlungen zur Geschichte der Medizin und der Naturwissenschaften ; 98
    Collection
    Keywords Coerper, Carl ; Gesundheitsfürsorge ; Rassenhygiene ; Geschichte 1925-1956 ; Deutschland ; Sozialhygiene ; Geschichte 1920-1960
    Subject Community Medicine ; Gesundheitshilfe ; Rassehygiene
    Language German
    Size 270 S. : Ill.
    Publisher Matthiesen
    Publishing place Husum
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Freie Univ., Diss.,1999 u.d.T.: Schütz, Horst: Zum Nutzen der Volksgesundheit
    HBZ-ID HT013969687
    ISBN 3-7868-4098-9 ; 978-3-7868-4098-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Ua II Zs 50 -98- verfügbar in Königswinter Königswinter

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  10. Book ; Thesis: Gesundheitsfürsorge zwischen humanitärem Anspruch und eugenischer Verpflichtung : Entwicklung und Kontinuität sozialhygienischer Anschauungen zwischen 1920 und 1960 am Beispiel von Prof. Dr. Carl Coerper

    Schütz, Horst

    Entwicklung und Kontinuität sozialhygienischer Anschauungen zwischen 1920 und 1960 am Beispiel von Prof. Dr. Carl Coerper

    2004  

    Title variant Zum Nutzen der Volksgesundheit
    Author's details von Horst Schütz
    Keywords Coerper, Carl ; Gesundheitsfürsorge ; Rassenhygiene ; Geschichte 1925-1956 ; Deutschland ; Sozialhygiene ; Geschichte 1920-1960
    Subject Community Medicine ; Gesundheitshilfe ; Rassehygiene
    Language German
    Size 270 S. : Ill., graph.Darst.
    Publisher Matthiesen
    Publishing place Husum
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Freie Univ., Diss.,1999 u.d.T.: Schütz, Horst: Zum Nutzen der Volksgesundheit
    HBZ-ID HT014130846
    ISBN 3-7868-4098-9 ; 978-3-7868-4098-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 3601 order for loan Magazin

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