Article: ModDotPlot-Rapid and interactive visualization of complex repeats.
bioRxiv : the preprint server for biology
2024
Abstract: Motivation: A common method for analyzing genomic repeats is to produce a sequence similarity matrix visualized via a dot plot. Innovative approaches such as StainedGlass have improved upon this classic visualization by rendering dot plots as a heatmap ... ...
Abstract | Motivation: A common method for analyzing genomic repeats is to produce a sequence similarity matrix visualized via a dot plot. Innovative approaches such as StainedGlass have improved upon this classic visualization by rendering dot plots as a heatmap of sequence identity, enabling researchers to better visualize multi-megabase tandem repeat arrays within centromeres and other heterochromatic regions of the genome. However, computing the similarity estimates for heatmaps requires high computational overhead and can suffer from decreasing accuracy. Results: In this work we introduce ModDotPlot, an interactive and alignment-free dot plot viewer. By approximating average nucleotide identity via a Availability and implementation: ModDotPlot is available at https://github.com/marbl/ModDotPlot. |
---|---|
Language | English |
Publishing date | 2024-04-19 |
Publishing country | United States |
Document type | Preprint |
DOI | 10.1101/2024.04.15.589623 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Inter-library loan at ZB MED
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.