Article ; Online: Corneal sensitivity in silicone hydrogel and rigid gas permeable contact lens wear.
Contact lens & anterior eye : the journal of the British Contact Lens Association
2023 Volume 46, Issue 5, Page(s) 101888
Abstract: Purpose: The aim of this prospective cross-sectional cohort study was to test the effect of silicone hydrogel (SH) and rigid gas permeable (RGP) contact lens (CL) wear on corneal sensitivity, applying the new Swiss Liquid Jet Aesthesiometer for Corneal ... ...
| Abstract | Purpose: The aim of this prospective cross-sectional cohort study was to test the effect of silicone hydrogel (SH) and rigid gas permeable (RGP) contact lens (CL) wear on corneal sensitivity, applying the new Swiss Liquid Jet Aesthesiometer for Corneal Sensitivity (SLACS) and the Cochet-Bonnet (CB) aesthesiometer, based on subject feedback (psychophysical method). Methods: Participants were recruited for three equally large groups: Group A (SH CL), Group B (RGP CL) and Group C (non-CL wearers). Inclusion criteria were healthy eyes and OSDI ≤ 13. Corneal sensory thresholds were determined twice during two visits, with aid of SLACS and CB. Results: 96 participants completed the study (n = 33 in groups A and C, n = 30 in group B); average age in group A: 27.42 ± 6.83 years, group B: 36.90 ± 9.68 years and group C: 26.06 ± 6.19 years. No statistically significant difference in corneal sensitivity was observed between the three groups for either method (p = 0.302 for SLACS, p = 0.266 for CB; Kruskal-Wallis rank sum test). Higher CSTs were obtained for males than for females in both CL groups with SLACS, and with CB only in the RGP CL group (p = 0.041 in Group A, p = 0.006 in Group B with SLACS; p = 0.041 in Group B with CB; bootstrap analysis with age correction and gender balancing). No correlation was observed between CL comfort and corneal sensitivity for neither method applied (for SLACS r = 0.097 and p = 0.51, for CB r = 0.17 and p = 0.15; robust linear mixed model). Conclusions: No difference in corneal sensitivity with CL compared to non-CL wear was noted in this study. However, lower levels of corneal sensitivity were observed in the male CL groups, warranting further investigation. |
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| MeSH term(s) | Female ; Humans ; Male ; Young Adult ; Adult ; Hydrogels ; Silicones ; Prospective Studies ; Cross-Sectional Studies ; Contact Lenses ; Cornea |
| Chemical Substances | Hydrogels ; Silicones |
| Language | English |
| Publishing date | 2023-07-06 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2004847-6 |
| ISSN | 1476-5411 ; 1367-0484 |
| ISSN (online) | 1476-5411 |
| ISSN | 1367-0484 |
| DOI | 10.1016/j.clae.2023.101888 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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