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  1. Book ; Thesis: Innovative Brustkrebsfrüherkennung mittels nicht-invasiver MRT-Diagnostik

    König, Franziska / Schlemmer, Heinz-Peter

    ein multiparametrischer, quantitativer Ansatz zur Differenzierung von Mamma-Läsionen

    2021  

    Institution Universität Heidelberg
    Author's details vorgelegt von Franziska Hildegard König (geb. Steudle) ; Doktorvater: Herr Prof. Dr. med. Dipl.-Phys. Hein-Peter Schlemmer
    Language German
    Size 108 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2022
    HBZ-ID HT030043567
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Radiologie der Gewalt

    Glemser, Philip / Krauskopf, Astrid / Schlemmer, Heinz-Peter / Yen, Kathrin

    Einführung in Methodik und Begutachtung für Radiologen und Rechtsmediziner

    2021  

    Author's details herausgegeben von Philip Alexander Glemser, Astrid Krauskopf, Heinz-Peter Schlemmer, Kathrin Yen. Mit Beiträgen von Alexander Bornik [und vielen weiteren]. Mit Geleitworten von Bettina Limperg, Michael Forsting und Burkhard Madea
    Keywords Radiologische Diagnostik ; Rechtsmedizin
    Subject Forensische Medizin ; Gerichtliche Medizin ; Gerichtsmedizin ; Diagnostische Radiologie ; Strahlendiagnostik
    Language German
    Size 476 Seiten, Illustrationen, Diagramme
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Publishing country Germany
    Document type Book
    Note Zugang zu Online-Ausgabe über Code
    HBZ-ID HT020997815
    ISBN 978-3-13-221371-5 ; 9783132213913 ; 9783132213814 ; 3-13-221371-3 ; 3132213918 ; 3132213810
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: The Cancer Epidemic : Globale Bedeutung der Krebserkrankungen und Situation der onkologischen Bildgebung.

    Schlemmer, Heinz-Peter

    Radiologie (Heidelberg, Germany)

    2022  Volume 63, Issue 1, Page(s) 49–56

    Abstract: A significant increase in the incidence of cancer is expected worldwide. In Europe, cancer will soon be the leading cause of death, ahead of cardiovascular disease. Concerted efforts at the scientific, medical, societal, and political levels are required ...

    Title translation The cancer epidemic : Global significance of cancer and the situation in oncological imaging.
    Abstract A significant increase in the incidence of cancer is expected worldwide. In Europe, cancer will soon be the leading cause of death, ahead of cardiovascular disease. Concerted efforts at the scientific, medical, societal, and political levels are required to address this problem on a global scale. High-quality oncological imaging is of particular importance in this regard. Access to it has been shown to have a significant impact on quality of care and survival. Imaging is an essential component of screening and early detection. In clinical oncology, imaging is essential for multidisciplinary diagnostics and personalized therapy. Likewise, imaging is necessary in translational and clinical research. Imaging techniques are also themselves the subject of research and development and, associated with this, are also of great importance as an economic factor. This article aims to provide insights into the global problem of oncology and the contribution that oncological imaging can make to its management.
    MeSH term(s) Humans ; Neoplasms/diagnostic imaging ; Neoplasms/epidemiology ; Medical Oncology/methods ; Diagnostic Imaging ; Europe
    Language German
    Publishing date 2022-12-21
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7056
    ISSN (online) 2731-7056
    DOI 10.1007/s00117-022-01092-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Thesis: Prädiktion der Kontinenzsituation nach radikaler Prostatektomie mittels standardisierter Auswertung der präoperativen MRT

    Wörner, Jan Michael / Schlemmer, Heinz-Peter

    2017  

    Institution Universität Heidelberg
    Author's details vorgelegt von Jan Michael Wörner aus Darmstadt ; Doktorvater: Prof. Dr. med. Dipl.-Phys. Heinz-Peter Schlemmer
    Language German
    Size 67 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2018
    HBZ-ID HT020128191
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: The Eye of the CT Scanner: The story of learning to see the invisible or from the fluorescent screen to the photon-counting detector.

    Schlemmer, Heinz-Peter

    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

    2021  Volume 193, Issue 9, Page(s) 1034–1049

    Abstract: Roentgen's photographs with the "new kind of rays" triggered a worldwide storm of enthusiasm in all social circles. It was a stroke of luck that the photographic dry plates available to him were also sensitive to invisible X-rays. The discovery, research ...

    Title translation Das Auge des Computertomografen: Die Geschichte vom Sehenlernen des Unsichtbaren oder vom Fluoreszenzschirm zum photonenzählenden Detektor.
    Abstract Roentgen's photographs with the "new kind of rays" triggered a worldwide storm of enthusiasm in all social circles. It was a stroke of luck that the photographic dry plates available to him were also sensitive to invisible X-rays. The discovery, research and utilization of X-rays are based on methods for making them visible, from fluorescent screens to photographic plates and digital X-ray detectors. From this point of view, this paper aims to outline the 125-year success story of X-ray imaging from its discovery to the recent development of photon-counting detectors. The scientific-historical view during the transition from the 19
    MeSH term(s) Phantoms, Imaging ; Photons ; Radiography ; Tomography, X-Ray Computed ; X-Rays
    Language German
    Publishing date 2021-03-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    ISSN (online) 1438-9010
    ISSN 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    DOI 10.1055/a-1308-2693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Eye of the CT Scanner: The story of learning to see the invisible or from the fluorescent screen to the photon-counting detector

    Schlemmer, Heinz-Peter

    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

    2021  Volume 193, Issue 09, Page(s) 1034–1049

    Abstract: Roentgen’s photographs with the “new kind of rays” triggered a worldwide storm of enthusiasm in all social circles. It was a stroke of luck that the photographic dry plates available to him were also sensitive to invisible X-rays. The discovery, research ...

    Abstract Roentgen’s photographs with the “new kind of rays” triggered a worldwide storm of enthusiasm in all social circles. It was a stroke of luck that the photographic dry plates available to him were also sensitive to invisible X-rays. The discovery, research and utilization of X-rays are based on methods for making them visible, from fluorescent screens to photographic plates and digital X-ray detectors. From this point of view, this paper aims to outline the 125-year success story of X-ray imaging from its discovery to the recent development of photon-counting detectors. The scientific-historical view during the transition from the 19 th to the 20 th century reveals an impressive period of profound scientific and social upheaval in which revolutionary discoveries and technological developments led to enormous progress in medicine. The cross-fertilization of physics and medicine and their combination with inventiveness, engineering and entrepreneurial spirit created the impressive possibilities of today’s imaging diagnostics. This contribution accompanies the Roentgen Lecture the author gave on November 13, 2020 in Roentgen’s birth house as part of its inauguration and the closing ceremony of the 101 st Congress of the German Roentgen Society in Remscheid-Lennep.
    Key Points: The development of computed tomography was a milestone in the methodological advancement of imaging with X-rays. In the detector pixel invisible X-rays are converted into digital electrical impulses, which the computer uses to create images. Photon-counting detectors could have significant diagnostic advantages for clinical applications.
    Citation Format: Schlemmer H, The Eye of the CT Scanner: The story of learning to see the invisible or from the fluorescent screen to the photon-counting detector. Fortschr Röntgenstr 2021; 193: 1034 – 1048

    Röntgens Fotografien mit der „neuen Art von Strahlen“ lösten einen weltweiten Begeisterungssturm in allen gesellschaftlichen Kreisen aus. Dabei war es ein Glücksfall, dass die ihm zu Verfügung stehenden fotografischen Trockenplatten auch für die unsichtbaren X-Strahlen empfindlich waren. Entdeckung, Erforschung und Nutzbarmachung von Röntgenstrahlen beruhen auf Methoden zur deren Sichtbarmachung, vom Fluoreszenzschirm über die Fotoplatte bis hin zum digitalen Röntgendetektor. Aus diesem Blickwinkel heraus möchte diese Arbeit die 125-jährige Erfolgsgeschichte der Röntgenbildgebung von der Entdeckung bis zur jüngsten Entwicklung photonenzählender Detektoren skizzieren. Die wissenschaftshistorische Betrachtung am Übergang des 19. zum 20. Jahrhundert offenbart eine eindrucksvolle Zeit tiefgreifender wissenschaftlicher und gesellschaftlicher Umbrüche, in der revolutionäre Entdeckungen und technologische Entwicklungen zu gewaltigen Fortschritten der Medizin führten. Die gegenseitige Befruchtung von Physik und Medizin und deren Verquickung mit Erfindergeist, Ingenieurskunst und unternehmerischem Geschick schufen die eindrucksvollen Möglichkeiten der bildgebenden Diagnostik von heute. Diese Arbeit begleitet die Röntgenvorlesung, die der Autor am 13. November 2020 im Röntgen-Geburtshaus im Rahmen von dessen Eröffnung sowie des feierlichen Abschlusses des 101. Deutschen Röntgenkongresses in Remscheid-Lennep gehalten hat.
    Kernaussagen: Die Entwicklung der Computertomografie markiert einen Meilenstein der methodischen Weiterentwicklung der Bildgebung mit Röntgenstrahlen. Im Detektorpixel werden die unseren Sinnen unzugänglichen Röntgenstrahlen in digitale elektrische Impulse umgewandelt, aus denen der Computer die Bilder errechnet. Photonenzählende Röntgendetektoren lassen deutliche diagnostische Vorteile für klinische Anwendungen erwarten.
    Zitierweise: Schlemmer H, The Eye of the CT Scanner: The story of learning to see the invisible or from the fluorescent screen to the photon-counting detector. Fortschr Röntgenstr 2021; 193: 1034 – 1049
    Keywords CT ; digital radiography ; radiations ; radiography ; CT ; digital radiography ; radiations ; radiography
    Language English
    Publishing date 2021-03-18
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    ISSN (online) 1438-9010
    ISSN 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    DOI 10.1055/a-1308-2693
    Database Thieme publisher's database

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  7. Article: Imaging in translational cancer research.

    Kurz, Felix T / Schlemmer, Heinz-Peter

    Cancer biology & medicine

    2022  Volume 19, Issue 11

    Abstract: This review is aimed at presenting some of the recent developments in translational cancer imaging research, with a focus on novel, recently established, or soon to be established cross-sectional imaging techniques for computed tomography (CT), magnetic ... ...

    Abstract This review is aimed at presenting some of the recent developments in translational cancer imaging research, with a focus on novel, recently established, or soon to be established cross-sectional imaging techniques for computed tomography (CT), magnetic resonance imaging (MRI), and positron-emission tomography (PET) imaging, including computational investigations based on machine-learning techniques.
    MeSH term(s) Translational Research, Biomedical ; Research ; Neoplasms/diagnostic imaging
    Language English
    Publishing date 2022-12-07
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2676322-9
    ISSN 2095-3941
    ISSN 2095-3941
    DOI 10.20892/j.issn.2095-3941.2022.0677
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Chancen von KI in der Onkologie am Beispiel der individualisierten Diagnostik und Behandlung von Prostatakrebs

    Schlemmer, Heinz-Peter / Hohenfellner, Markus

    Zeitschrift fuer medizinische Ethik

    2021  Volume 67, Issue 3, Page(s) 309–326

    Title translation Opportunities of AI in oncology using the example of individualized diagnosis and treatment of prostate cancer
    Keywords decision making ; computers ; cancer ; diagnosis ; risks and benefits ; technology assessment ; medical specialties
    Subject code AN
    Language German
    Document type Article
    ZDB-ID 1149764-6
    ISSN 0944-7652
    ISSN 0944-7652
    Database Ethics in Medicine (ETHMED)

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  9. Article ; Online: Multiparametrische MRT der Prostata : Wichtige radiologische Befunde für den Urologen.

    Schlemmer, Heinz-Peter

    Der Radiologe

    2017  Volume 57, Issue 8, Page(s) 621–630

    Abstract: Clinical/methodical issue: High prevalence of prostate cancer with multifocality and biological heterogeneity. Insufficient conventional urological diagnostics. Discrimination between significant and insignificant cancer needed.: Standard diagnostic ... ...

    Title translation Multiparametric MRI of the prostate : Important radiological findings for urologists.
    Abstract Clinical/methodical issue: High prevalence of prostate cancer with multifocality and biological heterogeneity. Insufficient conventional urological diagnostics. Discrimination between significant and insignificant cancer needed.
    Standard diagnostic methods: Digital rectal examination, prostate-specific antigen (PSA) serum level, systematic transrectal ultrasound (TRUS)-guided prostate biopsy.
    Methodical innovations: Multiparametric magnetic resonance imaging (mpMRI) including T2-weighted (T2w), diffusion-weighted and dynamic contrast-enhanced MRI according to the prostate imaging reporting and data system (PIRADS), MR-targeted biopsy, most frequently MR/TRUS image fusion biopsy.
    Findings and performance: Prostate cancer is characterized by low signal intensity on T2w MRI, restricted water diffusion and pronounced and early uptake of contrast enhancement. Sensitivity and specificity according to the current literature are ca. 80% and 90%, respectively.
    Practical recommendations: In cases of suspected prostate cancer, most accurate are mpMRI according to PIRADS and in cases of positive findings, MRI-targeted biopsy, most frequently as MRI/TRUS image fusion biopsy.
    MeSH term(s) Contrast Media ; Humans ; Image-Guided Biopsy/methods ; Magnetic Resonance Imaging/methods ; Male ; Prostate/diagnostic imaging ; Prostate/pathology ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/pathology ; Urologists
    Chemical Substances Contrast Media ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language German
    Publishing date 2017-08-03
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 505520-9
    ISSN 1432-2102 ; 0033-832X
    ISSN (online) 1432-2102
    ISSN 0033-832X
    DOI 10.1007/s00117-017-0277-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MG 106: Show issues

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  10. Article: Clinical MR Biomarkers.

    Paech, Daniel / Schlemmer, Heinz-Peter

    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer

    2020  Volume 216, Page(s) 719–745

    Abstract: Non-invasive magnetic resonance imaging (MRI) techniques are increasingly applied in the clinic with a fast growing body of evidence regarding its value for clinical decision making. In contrast to biochemical or histological markers, the key advantages ... ...

    Abstract Non-invasive magnetic resonance imaging (MRI) techniques are increasingly applied in the clinic with a fast growing body of evidence regarding its value for clinical decision making. In contrast to biochemical or histological markers, the key advantages of imaging biomarkers are the non-invasive nature and the spatial and temporal resolution of these approaches. The following chapter focuses on clinical applications of novel MR biomarkers in humans with a strong focus on oncologic diseases. These include both clinically established biomarkers (part 1-4) and novel MRI techniques that recently demonstrated high potential for clinical utility (part 5-7).
    MeSH term(s) Biomarkers/analysis ; Brain Neoplasms/diagnostic imaging ; Humans ; Magnetic Resonance Imaging
    Chemical Substances Biomarkers
    Language English
    Publishing date 2020-06-27
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 0080-0015
    ISSN 0080-0015
    DOI 10.1007/978-3-030-42618-7_21
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