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  1. Article ; Online: Use of new STOPP/START criteria in the care of older adults.

    Hanlon, Joseph T / Schmader, Kenneth E

    Journal of the American Geriatrics Society

    2023  Volume 72, Issue 1, Page(s) 318–320

    MeSH term(s) Humans ; Aged ; Potentially Inappropriate Medication List ; Inappropriate Prescribing ; Drug-Related Side Effects and Adverse Reactions
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.18613
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Medication Appropriateness Index: A Clinimetric Measure.

    Hanlon, Joseph T / Schmader, Kenneth E

    Psychotherapy and psychosomatics

    2022  Volume 91, Issue 2, Page(s) 78–83

    MeSH term(s) Humans ; Potentially Inappropriate Medication List ; Reproducibility of Results
    Language English
    Publishing date 2022-02-14
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 209490-3
    ISSN 1423-0348 ; 0033-3190
    ISSN (online) 1423-0348
    ISSN 0033-3190
    DOI 10.1159/000521699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Medication use quality and safety in older adults: 2022 update.

    Gray, Shelly L / Brandt, Nicole / Schmader, Kenneth E / Hanlon, Joseph T

    Journal of the American Geriatrics Society

    2023  

    Abstract: Improving the quality of medication use and medication safety are important priorities for healthcare providers who care for older adults. The objective of this article was to identify four exemplary articles with this focus in 2022. We selected high- ... ...

    Abstract Improving the quality of medication use and medication safety are important priorities for healthcare providers who care for older adults. The objective of this article was to identify four exemplary articles with this focus in 2022. We selected high-quality studies from an OVID search and hand searching of major high impact journals that advanced the field of research forward. The chosen articles cover domains related to deprescribing, medication safety, and optimizing medication use. The MedSafer Study, a cluster randomized clinical trial in Canada, evaluated whether patient specific deprescribing reports generated by electronic decision support software resulted in reduced adverse drug events in the 30 days post hospital discharge in older adults (domain: deprescribing). The second study, a retrospective cohort study using data from Premier Healthcare Database, examined in-hospital adverse clinical events associated with perioperative gabapentin use among older adults undergoing major surgery (domain: medication safety). The third study used an open-label parallel controlled trial in 39 Australian aged-care facilities to examine the effectiveness of a pharmacist-led intervention to reduce medication-induced deterioration and adverse reactions (domain: optimizing medication use). Lastly, the fourth study engaged experts in a Delphi method process to develop a consensus list of clinically important prescribing cascades that adversely affect older persons' health to aid clinicians to identify, prevent, and manage prescribing cascades (domain: optimizing medication use). Collectively, this review succinctly highlights pertinent topics related to promoting safe use of medications and promotes awareness of optimizing older adults' medication regimens.
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.18684
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  4. Article ; Online: Clin-Star corner: What's new at the interface of geriatrics, infectious diseases, and antimicrobial stewardship.

    Advani, Sonali D / Schmader, Kenneth E / Mody, Lona

    Journal of the American Geriatrics Society

    2022  Volume 70, Issue 8, Page(s) 2214–2218

    Abstract: Antibiotics are among the leading causes of adverse drug events in older adults. Short-course antibiotic therapy has been shown to work as well as the traditional longer durations for many types of infections. Antibiotic stewardship interventions ... ...

    Abstract Antibiotics are among the leading causes of adverse drug events in older adults. Short-course antibiotic therapy has been shown to work as well as the traditional longer durations for many types of infections. Antibiotic stewardship interventions including deprescribing strategies have shown a reduction in patient readmissions and mortality among older adults. We identified practice-changing clinical trials focusing on three major domains of overprescribing antibiotics in older adults - community-acquired pneumonia, urinary tract infections, and gram-negative bacteremia. The selected articles underscore the safety and effectiveness of shorter durations of antibiotic treatment for infections in older adults, thus highlighting an opportunity for deprescribing in the aging population. By optimizing antibiotic use, we stand to reduce adverse events and enhance overall health outcomes in older adults.
    MeSH term(s) Aged ; Anti-Bacterial Agents/therapeutic use ; Antimicrobial Stewardship ; Communicable Diseases/drug therapy ; Community-Acquired Infections ; Geriatrics ; Humans
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-06-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.17907
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Current treatment and future strategies for herpes zoster and postherpetic neuralgia

    Schmader, Kenneth E. / Harpaz, Rafael / Oxman, Michael N.

    (Clinical geriatrics ; 15,9, Suppl. 1 ; Annals of long-term care: clinical care and aging ; 15,9, Suppl. 1)

    2007  

    Author's details Kenneth E. Schmader ; Rafael Harpaz ; Michael N. Oxman
    Series title Clinical geriatrics ; 15,9, Suppl. 1
    Annals of long-term care: clinical care and aging ; 15,9, Suppl. 1
    Annals of long-term care
    Annals of long-term care ; clinical care and aging
    Collection Annals of long-term care
    Annals of long-term care ; clinical care and aging
    Language English
    Size 12 S. : Ill., graph. Darst.
    Publisher HMP Communications
    Publishing place Malvern, PA
    Publishing country United States
    Document type Book
    HBZ-ID HT015689071
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs A 5000 -15,9,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  6. Article ; Online: Expanding Evidence for Clinical Care of Older Adults: Beyond Clinical Trial Traditions and Finding New Approaches.

    Steinman, Michael A / Boyd, Cynthia M / Schmader, Kenneth E

    JAMA

    2021  Volume 326, Issue 6, Page(s) 475–476

    MeSH term(s) Aged ; Clinical Trials as Topic/legislation & jurisprudence ; Clinical Trials as Topic/standards ; Health Services for the Aged ; Health Status Disparities ; Humans ; National Institutes of Health (U.S.) ; Patient Selection ; Pragmatic Clinical Trials as Topic ; United States
    Language English
    Publishing date 2021-07-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2021.12134
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Measuring Underuse and Overuse of Medications.

    Hanlon, Joseph T / Schmader, Kenneth E

    Journal of the American Geriatrics Society

    2019  Volume 67, Issue 11, Page(s) 2428

    MeSH term(s) Health Status ; Polypharmacy
    Language English
    Publishing date 2019-08-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.16111
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  8. Article ; Online: Medication use quality and safety in older adults: 2020 update.

    Eshetie, Tesfahun C / Marcum, Zachary A / Schmader, Kenneth E / Gray, Shelly L

    Journal of the American Geriatrics Society

    2021  Volume 70, Issue 2, Page(s) 389–397

    Abstract: Improving the quality of medication use and medication safety are important priorities for prescribers who care for older adults. The objective of this article was to identify four exemplary articles with this focus in 2020. We selected high-quality ... ...

    Abstract Improving the quality of medication use and medication safety are important priorities for prescribers who care for older adults. The objective of this article was to identify four exemplary articles with this focus in 2020. We selected high-quality studies that moved the field of research forward and were not merely replication studies. The chosen articles cover domains related to deprescribing, medication safety, and optimizing medication use. The first study, a noninferiority randomized clinical trial in England, evaluated whether antihypertensive medication reduction is possible without significant changes in systolic blood pressure control or adverse events over the 12-week follow-up (domain: deprescribing). The second study, a prospective cohort study of women at Kaiser Permanente Southern, California, examined the association between bisphosphonate use and atypical femur fracture (domain: medication safety). The third study examined the effectiveness and safety of a multifaceted antimicrobial stewardship and quality improvement initiative in reducing unnecessary antimicrobial use for unlikely cystitis cases in noncatheterized residents in 25 nursing homes across the United States (domain: optimizing medication use). Lastly, the fourth study, a population-based cohort study in the United Kingdom, examined the association of tramadol use with risk of hip fracture (domain: medication safety). Collectively, this review succinctly highlights pertinent topics related to promoting safe use of medications and promotes awareness of optimizing older adults' medication regimens.
    MeSH term(s) Aged, 80 and over ; Analgesics, Opioid/adverse effects ; Antihypertensive Agents/therapeutic use ; Antimicrobial Stewardship ; California ; Cystitis/diagnosis ; Cystitis/drug therapy ; Deprescriptions ; Diphosphonates/adverse effects ; Hospitalization ; Humans ; Inappropriate Prescribing ; Patient Safety ; Polypharmacy ; Prospective Studies ; Randomized Controlled Trials as Topic ; Tramadol/adverse effects ; United Kingdom
    Chemical Substances Analgesics, Opioid ; Antihypertensive Agents ; Diphosphonates ; Tramadol (39J1LGJ30J)
    Language English
    Publishing date 2021-12-13
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.17603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Medication Use Quality and Safety in Older Adults: 2019 Update.

    Ailabouni, Nagham J / Marcum, Zachary A / Schmader, Kenneth E / Gray, Shelly L

    Journal of the American Geriatrics Society

    2021  Volume 69, Issue 2, Page(s) 336–341

    Abstract: Improving the quality of medication use and medication safety are important priorities for prescribers who care for older adults. The objective of this article was to identify four exemplary articles with this focus in 2019. We selected high-quality ... ...

    Abstract Improving the quality of medication use and medication safety are important priorities for prescribers who care for older adults. The objective of this article was to identify four exemplary articles with this focus in 2019. We selected high-quality studies that moved the field of research forward and were not merely replication studies. The chosen articles cover domains related to aspects of suboptimal prescribing and medication safety. The first study used a nationally representative sample of Medicare beneficiaries to examine the continuation of medications with limited benefit in patients admitted for cancer and non-cancer diagnoses in hospice (domain: potentially inappropriate medications). The second study, a retrospective cohort study of older adults in Ontario, Canada, assessed the association between prescribing oral anticoagulants in an emergency department relative to not prescribing anticoagulants in the emergency department and their persistence at 6 months (domain: underuse of medications). The third study, a cluster randomized trial in Quebec, Canada, evaluated the effect of conducting electronic medication reconciliation on several outcomes including adverse drug events and medication discrepancies (domain: medication safety). Lastly, the fourth study, a retrospective study using national inpatient and outpatient Veteran Health Administration combined with clinical and Medicare Claims data, examined the effects of intensification of antihypertensive medications on older adults' likelihood for hospital re-admission and other important clinical outcomes (domain: medication safety). Collectively, this review succinctly highlights pertinent topics related to promoting safe use of medications and promotes awareness of optimizing older adults' medication regimens.
    MeSH term(s) Aged, 80 and over ; Humans ; Medication Therapy Management/standards ; Patient Safety ; Polypharmacy ; Potentially Inappropriate Medication List ; Prescription Drugs/pharmacology
    Chemical Substances Prescription Drugs
    Language English
    Publishing date 2021-01-12
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.17018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Partnering to cope with pain: A pilot study of a caregiver-assisted pain coping skills intervention for patients with cognitive impairment and dementia.

    Porter, Laura S / Weiner, Debra K / Ramos, Katherine / Barnes, Deborah E / Schmader, Kenneth E / Gwyther, Lisa / Ritchie, Christine S / Keefe, Francis J

    Palliative & supportive care

    2023  Volume 20, Issue 6, Page(s) 785–793

    Abstract: Objective: To develop a new caregiver-assisted pain coping skills training protocol specifically tailored for community-dwelling persons with cognitive impairment and pain, and assess its feasibility and acceptability.: Method: In Phase I, we ... ...

    Abstract Objective: To develop a new caregiver-assisted pain coping skills training protocol specifically tailored for community-dwelling persons with cognitive impairment and pain, and assess its feasibility and acceptability.
    Method: In Phase I, we conducted interviews with 10 patient-caregiver dyads to gather feedback about intervention content and delivery. Phase II was a single-arm pilot test to evaluate the intervention's feasibility and acceptability. Dyads in the pilot study (
    Results: Dyads responded positively to the pain coping skills presented in the interviews; their feedback was used to refine the intervention. Findings from the pilot study suggested that the intervention was feasible and acceptable. 69% of eligible dyads consented, 82% completed all five intervention sessions, and 100% completed the post-treatment assessment. Caregivers reported high satisfaction ratings. They also reported using the pain coping skills on a regular basis, and that they found most of the skills helpful and easy to use.
    Significance of results: These preliminary findings suggest that a caregiver-assisted pain coping skills intervention is feasible and acceptable, and that it may be a promising approach to managing pain in patients with cognitive impairment.
    MeSH term(s) Humans ; Caregivers/psychology ; Pilot Projects ; Adaptation, Psychological ; Pain ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/therapy ; Dementia/complications ; Dementia/therapy ; Feasibility Studies
    Language English
    Publishing date 2023-03-20
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2454009-2
    ISSN 1478-9523 ; 1478-9515
    ISSN (online) 1478-9523
    ISSN 1478-9515
    DOI 10.1017/S1478951521001747
    Database MEDical Literature Analysis and Retrieval System OnLINE

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