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  1. Book ; Thesis: Die Analfistelkrankheit

    Schmid, Marina

    Ergebnisse nach operativer Therapie

    1988  

    Size 87 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Erlangen-Nürnberg, Univ., Diss., 1988
    HBZ-ID HT003332883
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    89 D 4486 order for loan Magazin

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  2. Article ; Online: Structure and Function of an Elongation Factor P Subfamily in Actinobacteria.

    Pinheiro, Bruno / Scheidler, Christopher M / Kielkowski, Pavel / Schmid, Marina / Forné, Ignasi / Ye, Suhui / Reiling, Norbert / Takano, Eriko / Imhof, Axel / Sieber, Stephan A / Schneider, Sabine / Jung, Kirsten

    Cell reports

    2020  Volume 30, Issue 13, Page(s) 4332–4342.e5

    Abstract: Translation of consecutive proline motifs causes ribosome stalling and requires rescue via the action of a specific translation elongation factor, EF-P in bacteria and archaeal/eukaryotic a/eIF5A. In Eukarya, Archaea, and all bacteria investigated so far, ...

    Abstract Translation of consecutive proline motifs causes ribosome stalling and requires rescue via the action of a specific translation elongation factor, EF-P in bacteria and archaeal/eukaryotic a/eIF5A. In Eukarya, Archaea, and all bacteria investigated so far, the functionality of this translation elongation factor depends on specific and rather unusual post-translational modifications. The phylum Actinobacteria, which includes the genera Corynebacterium, Mycobacterium, and Streptomyces, is of both medical and economic significance. Here, we report that EF-P is required in these bacteria in particular for the translation of proteins involved in amino acid and secondary metabolite production. Notably, EF-P of Actinobacteria species does not need any post-translational modification for activation. While the function and overall 3D structure of this EF-P type is conserved, the loop containing the conserved lysine is flanked by two essential prolines that rigidify it. Actinobacteria's EF-P represents a unique subfamily that works without any modification.
    MeSH term(s) Actinobacteria/metabolism ; Amino Acid Motifs ; Amino Acid Sequence ; Amino Acids/metabolism ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Conserved Sequence ; Crystallography, X-Ray ; Models, Molecular ; Peptide Elongation Factors/chemistry ; Peptide Elongation Factors/metabolism ; Phylogeny ; Protein Processing, Post-Translational ; Proteomics ; Structure-Activity Relationship
    Chemical Substances Amino Acids ; Bacterial Proteins ; Peptide Elongation Factors ; factor EF-P
    Language English
    Publishing date 2020-04-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2020.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Towards quantification of the crucial impact of auger recombination for the efficiency droop in (AlInGa)N quantum well structures.

    Nirschl, Anna / Binder, Michael / Schmid, Marina / Pietzonka, Ines / Lugauer, Hans-Jürgen / Zeisel, Roland / Sabathil, Matthias / Bougeard, Dominique / Galler, Bastian

    Optics express

    2016  Volume 24, Issue 3, Page(s) 2971–2980

    Abstract: Recent experimental investigations on the reduction of internal quantum efficiency with increasing current density in (AlInGa)N quantum well structures show that Auger recombination is a significant contributor to the so-called "droop" phenomenon. Using ... ...

    Abstract Recent experimental investigations on the reduction of internal quantum efficiency with increasing current density in (AlInGa)N quantum well structures show that Auger recombination is a significant contributor to the so-called "droop" phenomenon. Using photoluminescence (PL) test structures, we find Auger processes are responsible for at least 15 % of the measured efficiency droop. Furthermore, we confirm that electron-electron-hole (nnp) is stronger than electron-hole-hole (npp) Auger recombination in standard LEDs. The ratio of respective Auger coefficients is determined to be in the range 1 < Cnnp/Cnpp ≤ 12. This asymmetry is shown to limit the detection efficiency of Auger processes in our PL-based approach.
    Language English
    Publishing date 2016-02-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.24.002971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prospective mental imagery in patients with major depressive disorder or anxiety disorders.

    Morina, Nexhmedin / Deeprose, Catherine / Pusowski, Christina / Schmid, Marina / Holmes, Emily A

    Journal of anxiety disorders

    2011  Volume 25, Issue 8, Page(s) 1032–1037

    Abstract: Prospective negative cognitions are suggested to play an important role in maintaining anxiety disorders and major depressive disorder (MDD). However, little is known about positive prospective mental imagery. This study investigated differences in ... ...

    Abstract Prospective negative cognitions are suggested to play an important role in maintaining anxiety disorders and major depressive disorder (MDD). However, little is known about positive prospective mental imagery. This study investigated differences in prospective mental imagery among 27 patients with anxiety disorders, 24 patients with MDD, and 32 control participants. Measures of both deliberately generated and intrusive imagery were completed. Results indicated that both patients with anxiety disorders and those with MDD provided poorer vividness ratings for deliberately generated prospective positive scenarios compared to the control group. Patients with anxiety disorders showed a greater ability to vividly generate imagery for prospective negative scenarios than both patients with MDD and control participants. Finally, both clinical groups reported greater levels of intrusive prospective imagery of personally-relevant events as compared to the control group. The current findings underline the necessity to target prospective positive mental imagery in treating MDD and anxiety disorders.
    MeSH term(s) Adult ; Anxiety Disorders/psychology ; Depressive Disorder, Major/psychology ; Female ; Humans ; Imagination ; Male ; Middle Aged
    Language English
    Publishing date 2011-07-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 619417-5
    ISSN 1873-7897 ; 0887-6185
    ISSN (online) 1873-7897
    ISSN 0887-6185
    DOI 10.1016/j.janxdis.2011.06.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3269: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Thesis: Die Analfistelkrankheit

    Schmid, Marina

    Ergebnisse nach operativer Therapie

    1988  

    Author's details Marina Schmid
    Language Undetermined
    Size 87 S, graph. Darst, 21 cm
    Document type Book ; Thesis
    Thesis / German Habilitation thesis @Erlangen, Nürnberg, Univ., Diss. : 1988
    Database Former special subject collection: coastal and deep sea fishing

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  6. Article: Prospective mental imagery in patients with major depressive disorder or anxiety disorders

    Morina, Nexhmedin / Deeprose, Catherine / Pusowski, Christina / Schmid, Marina / Holmes, Emily A.

    Journal of Anxiety Disorders

    2011  Volume 25, Issue 8, Page(s) 1032–1037

    Abstract: Explored the role of deliberately generated and intrusive real-word mental imagery in clinical samples of patients with major depressive disorder (MDD) and anxiety disorders. 24 patients with MDD (mean age 42 years), 27 patients with anxiety disorders ( ... ...

    Title translation Prospektive bildhafte Vorstellung bei Patienten mit Depression oder Angststörung
    Abstract Explored the role of deliberately generated and intrusive real-word mental imagery in clinical samples of patients with major depressive disorder (MDD) and anxiety disorders. 24 patients with MDD (mean age 42 years), 27 patients with anxiety disorders (mean age 35 years), and 32 healthy controls (mean age 38 years) completed questionnaires including the Hospital Anxiety and Depression Scale (HADS), the Positive and Negative Affect Schedule (PANAS), and the Impact of Future Event Scale (IFES) as well as the Prospective Imagery Task (PIT). Results included 3 major findings: (1) Depressed patients had difficulty imagining positive future events; (2) patients suffering from anxiety disorders imagined negative prospective images more vividly than healthy participants, and (3) both groups of patients (anxiety disorder and MDD) reported a greater degree of intrusive, involuntary prospective images than the healthy control group. Contrary to expectation, patients with anxiety disorders reported impoverished vividness of positive prospective events. Implications for cognitive theory, and cognitive behavioral therapy are discussed including the suggested promotion of deliberate positive imagery via systematic training for depressed and anxious patients. It is also suggested that mood disorder patients (MDD) could benefit from techniques that target intrusive negative imagery (e.g., imagery rescripting or simple exposure).
    Keywords Angststörungen ; Anxiety Disorders ; Bildhafte Vorstellung ; Cognitions ; Cognitive Processes ; Erwartungen ; Expectations ; Imagery ; Kognitionen (Denkinhalte) ; Kognitive Prozesse ; Major Depression
    Language English
    Document type Article
    ZDB-ID 619417-5
    ISSN 1873-7897 ; 0887-6185
    ISSN (online) 1873-7897
    ISSN 0887-6185
    DOI 10.1016/j.janxdis.2011.06.012
    Database PSYNDEX

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3269: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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