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  1. Book: Grundlegender Zeichen- und Wortschatz zur traditionellen chinesischen Medizin

    Schmidt, Muhammad Wolfgang G. A.

    mit einem ergänzenden Registerteil Deutsch – Chinesisch und Anleitungen und Übungsvorlagen zum Schreiben der chinesischen Zeichen sowie zwei Radikaltabellen

    2016  

    Author's details Muhammad Wolfgang G.A. Schmidt
    Keywords Dreifacher Erwärmet ; Essenz des Lebens ; Krankheitsursachen ; Meridiane und Leitbahnen ; Radikaltabellen ; Traditionelle Chinesische Medizin ; Yin und Yang ; Zang- und Fu-Organe ; Zeichen- und Wortschatz ; Chinesische Medizin ; Fachsprache ; Chinesische Schrift ; Schriftzeichen
    Subject Chinesisch ; Berufssprache ; Fachkommunikation ; Language for special purposes ; LSP ; Language for specific purposes ; Traditionelle chinesische Medizin ; TCM
    Subject code 610.95103
    Language Chinese ; German
    Size XXIX, 291 Seiten, Illustrationen, 23 cm, 450 g
    Edition Zhong de ban
    Publisher Viademica Verlag Berlin
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT019160285
    ISBN 978-3-939290-78-0 ; 3-939290-78-5
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online ; E-Book: Wörterbuch Traditionelle Chinesische Medizin

    Schmidt, Muhammad Wolfgang G. A.

    Grundwissen zu Geschichte, Kultur, Körper, Krankheiten und Therapie in Stichworten von A - Z

    2016  

    Title translation Handbuch der chinesischen Heilkunst
    Author's details Muhammad Wolfgang G. A. Schmidt
    Language German
    Size 1 Online-Ressource (VI, 325 Seiten), Illustrationen
    Publisher disserta Verlag
    Publishing place Hamburg
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019463866
    ISBN 978-3-95935-305-2 ; 9783959353045 ; 3-95935-305-7 ; 3959353049
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Thesis: Ischämie- Reperfusionsschaden des Lebertransplantates

    Schmidt, Matthias Wilfried

    Interleukin 2 und Interleukin 2-Rezeptor im peri- und potoperativen Verlauf

    2002  

    Author's details vorgelegt von Matthias Wilfried Schmidt
    Language German
    Size 71 S. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 2002
    HBZ-ID HT013515272
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Quantitative and Qualitative Evaluation of Plant Intake in Laying Hens: n-Alkanes as Predictive Fecal Markers for Dietary Composition Assessment.

    Dardabou, Laid / Martínez-Ávila, José Carlos / Schmidt, Markus Werner / Dublecz, Károly / Schwarz, Christiane / Ibáñez, Miguel Angel / Gierus, Martin

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 3

    Abstract: The shift in animal welfare standards towards free-range housing for laying hens in the EU has raised questions about changes in dietary composition. Accurate assessment of outdoor plant material intake is crucial for effective feeding strategies. This ... ...

    Abstract The shift in animal welfare standards towards free-range housing for laying hens in the EU has raised questions about changes in dietary composition. Accurate assessment of outdoor plant material intake is crucial for effective feeding strategies. This study introduces an approach using n-alkanes as markers to determine plant intake in laying hens, involving n-alkane recovery rate assessment, discriminant analysis and linear equation-solving for both qualitative and quantitative assessment, respectively, considering systematic n-alkane combinations. Two diets: a standard commercial diet and a diet incorporating 1% alfalfa were tested. Chemical analyses showed an altered n-alkane profile due to alfalfa inclusion, resulting a recovery rates ranging from 30-44% depending on the n-alkane type and diet. Statistical analysis revealed significant differences in recovery rates among the different alkanes for the same diets and between the diets for the same alkane, together with an interaction between n-alkane carbon chain length and initial concentration in the diet. The method accurately predicted plant inclusion, with a slight overestimation (2.80%) using the combination C25-C29-C33. Accurate qualitative classification of the animals based on fecal n-alkanes profiles was observed. The study successfully demonstrated the utility of n-alkanes for estimating dietary composition, providing a non-invasive approach for future free-range studies.
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14030378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Near-Infrared (NIR) Spectroscopy as an Alternative for Predicting n-Alkane Concentration in Excreta of Laying Hens: NIR-Generated Data for Dietary Composition Estimation.

    Dardabou, Laid / Martínez Ávila, José Carlos / Schmidt, Markus Werner / Dublecz, Károly / Schwarz, Christiane / Ibáñez, Miguel Angel / Gierus, Martin

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 5

    Abstract: N-alkanes offer a promising approach for assessing the nutritional contribution of external sources to the diets of laying hens in free-range production systems. However, traditional laboratory methods, involving extraction, purification and gas ... ...

    Abstract N-alkanes offer a promising approach for assessing the nutritional contribution of external sources to the diets of laying hens in free-range production systems. However, traditional laboratory methods, involving extraction, purification and gas chromatographic analysis, are both economically burdensome and time-consuming. Near-infrared spectroscopy (NIRS) is emerging as a viable alternative, with varying degrees of accuracy depending on the chemical nature and concentration of the component of interest. In our research, we focus on the accuracy of NIRS in predicting the concentrations of n-alkanes (C25-C33) in excreta under simulated free-range conditions with two different diets: one containing a commercial feed with minimal n-alkane content and another containing 1% alfalfa on top of the commercial feed. Spectra processing and calibration were tailored for each n-alkane, with NIRS performance influenced by diet type. Notably, plant predictions using NIR-generated data were consistent with laboratory results, despite a slight tendency toward overestimation (3.40% using the NIRS-generated C25-C29-C33 combination versus 2.80% using laboratory analysis). This indicates the potential of NIRS as an efficient tool to assess n-alkanes in excreta of laying hens and, consequently, the nutritional contribution of the free-range environment, providing rapid and cost-effective results.
    Language English
    Publishing date 2024-03-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14050806
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hybrid Correlation Energy (HyCE): An Approach Based on Separate Evaluations of Internal and External Components.

    Ivanic, Joseph / Schmidt, Michael W

    The journal of physical chemistry. A

    2018  Volume 122, Issue 23, Page(s) 5223–5237

    Abstract: A novel hybrid correlation energy (HyCE) approach is proposed that determines the total correlation energy via distinct computation of its internal and external components. This approach evolved from two related studies. First, rigorous assessment of the ...

    Abstract A novel hybrid correlation energy (HyCE) approach is proposed that determines the total correlation energy via distinct computation of its internal and external components. This approach evolved from two related studies. First, rigorous assessment of the accuracies and size extensivities of a number of electron correlation methods, that include perturbation theory (PT2), coupled-cluster (CC), configuration interaction (CI), and coupled electron pair approximation (CEPA), shows that the CEPA(0) variant of the latter and triples-corrected CC methods consistently perform very similarly. These findings were obtained by comparison to near full CI results for four small molecules and by charting recovered correlation energies for six steadily growing chain systems. Second, by generating valence virtual orbitals (VVOs) and utilizing the CEPA(0) method, we were able to partition total correlation energies into internal (or nondynamic) and external (or dynamic) parts for the aforementioned six chain systems and a benchmark test bed of 36 molecules. When using triple-ζ basis sets it was found that per orbital internal correlation energies were appreciably larger than per orbital external energies and that the former showed far more chemical variation than the latter. Additionally, accumulations of external correlation energies were seen to proceed smoothly, and somewhat linearly, as the virtual space is gradually increased. Combination of these two studies led to development of the HyCE approach, whereby the internal and external correlation energies are determined separately by CEPA(0)/VVO and PT2/external calculations, respectively. When applied to the six chain systems and the 36-molecule benchmark test set it was found that HyCE energies followed closely those of triples-corrected CC and CEPA(0) while easily outperforming MP2 and CCSD. The success of the HyCE approach is more notable when considering that its cost is only slightly more than MP2 and significantly cheaper than the CC approaches.
    Language English
    Publishing date 2018-06-14
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.8b01794
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Effect of Boron Clusters on the Ignition Reaction of HNO

    Schmidt, Michael W / Gordon, Mark S

    The journal of physical chemistry. A

    2017  Volume 121, Issue 41, Page(s) 8003–8011

    Abstract: Many ionic liquids containing the dicynamide anion ( ... ...

    Abstract Many ionic liquids containing the dicynamide anion (DCA
    Language English
    Publishing date 2017-10-19
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.7b07996
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Video-based learning of coping strategies for common errors improves laparoscopy training-a randomized study.

    Lang, F / Gerhäuser, A S / Wild, C / Wennberg, E / Schmidt, M W / Wagner, M / Müller-Stich, B P / Nickel, F

    Surgical endoscopy

    2023  Volume 37, Issue 5, Page(s) 4054–4064

    Abstract: Aims: The aim of this study was to investigate whether shifting the focus to solution orientation and developing coping strategies for common errors could increase the efficiency of laparoscopic training and influence learning motivation. The concept of ...

    Abstract Aims: The aim of this study was to investigate whether shifting the focus to solution orientation and developing coping strategies for common errors could increase the efficiency of laparoscopic training and influence learning motivation. The concept of coping has been particularly defined by the psychologist Richard Lazarus [Lazarus and Folkman in Stress, appraisal, and coping, Springer publishing company, New York, 1984]. Based on this model, we examined the use of observational learning with a coping model for its effectiveness as a basic teaching model in laparoscopic training.
    Methods: 55 laparoscopically naive medical students learned a standardized laparoscopic knot tying technique with video-based instructions. The control group was only offered a mastery video that showed the ideal technique and was free from mistakes. The intervention group was instructed on active error analysis and watched freely selectable videos of common errors including solution strategies (coping model) in addition to the mastery videos.
    Results: There was no statistically significant difference between the intervention and control groups for number of knot tying attempts until proficiency was reached (18.8 ± 5.5 vs. 21.3 ± 6.5, p = 0.142). However, there was a significantly higher fraction of knots achieving technical proficiency in the intervention group after first use of the coping model (0.7 ± 0.1 vs. 0.6 ± 0.2, p = 0.026). Additionally, the proportion of blinded attempts that met the criteria for technical proficiency was significantly higher for the intervention group at 60.9% vs. 38.0% in control group (p = 0.021). The motivational subscore "interest" of the validated score on current motivation (QCM) was significantly higher for the intervention group (p = 0.032), as well as subjective learning benefit (p = 0.002) and error awareness (p < 0.001).
    Conclusion: Using video-based learning of coping strategies for common errors improves learning motivation and understanding of the technique with a significant difference in its qualitative implementation in laparoscopy training. The ability to think in a solution-oriented, independent way is necessary in surgery in order to recognize and adequately deal with technical difficulties and complications.
    MeSH term(s) Humans ; Education, Distance ; Suture Techniques/education ; Clinical Competence ; Adaptation, Psychological ; Laparoscopy/education
    Language English
    Publishing date 2023-03-21
    Publishing country Germany
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-023-09969-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Efficacy of pembrolizumab in advanced cancer of the vulva: a systematic review and single-arm meta-analysis.

    Schwab, Roxana / Schiestl, Lina Judit / Cascant Ortolano, Lorena / Klecker, Philip Herbert / Schmidt, Mona Wanda / Almstedt, Katrin / Heimes, Anne-Sophie / Brenner, Walburgis / Stewen, Kathrin / Schmidt, Marcus / Hasenburg, Annette

    Frontiers in oncology

    2024  Volume 14, Page(s) 1352975

    Abstract: Introduction: Vulvar cancer carries a favourable prognosis in early stages. However, therapeutic options for advanced or recurrent cases are limited despite a variety of therapeutic modalities, such as extensive surgical resection, chemotherapy, and ... ...

    Abstract Introduction: Vulvar cancer carries a favourable prognosis in early stages. However, therapeutic options for advanced or recurrent cases are limited despite a variety of therapeutic modalities, such as extensive surgical resection, chemotherapy, and radiotherapy. The most important emerging treatment modalities are immune checkpoint inhibitors. This systematic review and meta-analysis aims to assess the efficacy and safety of pembrolizumab, an immune checkpoint inhibitor, in women with advanced vulvar cancer.
    Materials and methods: Following a comprehensive search, review, and appraisal, two relevant single-arm studies were included. Meta-analysis was conducted using R4.3.0 software and RStudio 2023.03.0, presenting the overall effect size with a 95% confidence interval. Heterogeneity was assessed using I
    Results: Out of 154 studies screened for eligibility, two single-arm studies involving 119 patients receiving pembrolizumab for advanced vulvar cancer were included. The pooled objective response rate (ORR) was overall 10% (95% CI: 0.00-0.84) and 9% (95% CI: 0.00-0.89) in the PD-L1 positive subgroup. In the intention-to-treat (ITT) population, 31% (95% CI: 0.04-0.85) exhibited any clinical benefit (complete response, partial response, or stable disease). In the ITT population at six months, progression-free survival (PFS) was 19% (95% CI: 0.01-0.82), and overall survival (OS) was 48% (95% CI: 0.08-0.90). At 12 months, PFS decreased to 9% (95% CI: 0.00-0.85), and OS was 33% (95% CI: 0.04-0.85). No statistically significant heterogeneity was observed in PFS and OS analyses.
    Discussion and conclusion: This study suggests that one-third of women with advanced or recurrent vulvar cancer may, without the influence of PD-L1 status, benefit from pembrolizumab treatment despite a decline in both PFS and OS at 12 months. These findings provide support for considering pembrolizumab in the treatment paradigm for this specific subset of cancer patients.
    Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42023391888.
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1352975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The PAncreatic Surgery Composite Endpoint PACE - Development and Validation of a Clinically Relevant Endpoint Requiring Lower Sample Sizes.

    Nickel, Felix / Kuemmerli, Christoph / Müller, Philip C / Schmidt, Mona W / Schmidt, Leon P / Wise, Philipp / Klotz, Rosa / Tjaden, Christine / Diener, Markus / Probst, Pascal / Hackert, Thilo / Büchler, Markus W

    Annals of surgery

    2024  

    Abstract: Objective: To provide a composite endpoint in pancreatic surgery.: Summary background data: Single endpoints in prospective and randomized studies have become impractical due to their low frequency and the marginal benefit of new interventions.: ... ...

    Abstract Objective: To provide a composite endpoint in pancreatic surgery.
    Summary background data: Single endpoints in prospective and randomized studies have become impractical due to their low frequency and the marginal benefit of new interventions.
    Methods: Data from prospective studies were used to develop (n=1273) and validate (n=544) a composite endpoint based on postoperative pancreatic fistula, post-pancreatectomy hemorrhage as well as reoperation and reinterventions. All patients had pancreatectomies of different extents. The association of the developed PAncreatic surgery Composite Endpoint (PACE) with prolonged length of hospital stay (LOS) >75th percentile and mortality was assessed. A single-institution database was used for external validation (n = 2666). Sample size calculations were made for single outcomes and the composite endpoint.
    Results: In the internal validation cohort, the PACE demonstrated an AUC of 78.0%, a sensitivity of 90.4% and a specificity of 67.6% in predicting a prolonged LOS. In the external cohort, the AUC was 76.9%, the sensitivity 73.8% and the specificity 80.1%. The 90-day mortality rate was significantly different for patients with a positive versus a negative PACE both in the development and internal validation cohort (5.1% vs 0.9%; P< 0.001), as well as in the external validation cohort (8.5% vs 1.2%, P< 0.001). The PACE enabled sample size reductions of up to 80.5% compared to single outcomes.
    Conclusion: The PACE performed well in predicting prolonged hospital stays and can be used as a standardized and clinically relevant endpoint for future prospective trials enabling lower sample sizes and therefore improved feasibility compared to single outcome parameters.
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000006194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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