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  1. Book ; Online: Kontaktverbindungen für aussteifende Scheiben aus Brettsperrholz

    Schmidt, Tobias

    2018  

    Abstract: Cross-laminated timber (CLT) is already being used successfully in residential, commercial and industrial buildings for different reasons. High in-plane shear strength and stiffness of the CLT itself make CLT members especially suited for bracing ... ...

    Abstract Cross-laminated timber (CLT) is already being used successfully in residential, commercial and industrial buildings for different reasons. High in-plane shear strength and stiffness of the CLT itself make CLT members especially suited for bracing elements with in-plane loads. To better use the potential of CLT under static in-plane loading, so called contact joints were developed with increased stiffness and load-carrying capacities using CNC automatic processing machines
    Keywords Technology (General)
    Size 1 electronic resource (VI, 249 p. p.)
    Publisher KIT Scientific Publishing
    Publishing place Verlagsort nicht ermittelbar
    Document type Book ; Online
    Note GERMAN ; Open Access
    HBZ-ID HT020196292
    ISBN 9783731508038 ; 3731508036
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Thesis: Indikationen, Komplikationen und Ergebnisse der Ellenbogenarthroskopie

    Schmidt, Thomas

    eine retrospektive Ergebnisbeurteilung mit Korrelationsanalyse des Patient-Rated-Elbow-Evaluation (PREE)-Scores in seiner deutschsprachigen Version

    2016  

    Author's details vorgelegt von Thomas Schmidt
    Language German
    Size 19 Seiten, Seite 220-225, 1 Diagramm, 30 cm
    Publishing place Erlangen-Nürnberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Friedrich-Alexander-Universität Erlangen-Nürnberg, 2016
    Note Enthält 1 Sonderabdruck
    HBZ-ID HT018997377
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 E 978 order for loan Magazin

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  3. Book ; Thesis: Auswirkung einer manualtherapeutischen Behandlung auf spezifische ganganalytische Parameter bei Personen mit lumbalen Rückenschmerzen

    Schmidt, Tobias

    2015  

    Author's details vorgelegt von Tobias Schmidt
    Language German
    Size XI, 71 Blätter, Illustrationen, Diagramme
    Publishing place Hamburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Hamburg, 2016
    HBZ-ID HT019193997
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 E 1905 order for loan Magazin

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  4. Book ; Thesis: Induction and phosphorylation of the small heat schock proteins HspB1/Hsp25 and HspB5/alphaB-crystallin in the rat retina after optic nerve injury

    Schmidt, Thomas

    2013  

    Author's details Thomas Schmidt
    Keywords Phosphorylation ; HSP27 Heat-shock proteins ; Crystallins ; Optic nerve injuries
    Language English
    Size 120 Bl. : zahlr. Ill.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Ulm, Univ., Diss., 2013
    HBZ-ID HT018309414
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 E 800 order for loan Magazin

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  5. Book ; Thesis: Vergleichende ganganalytische Untersuchung von Personen mit lumbalen Rückenschmerzen und gesunden Personen

    Schmidt, Tobias

    2013  

    Author's details vorgelegt von: Tobias Schmidt
    Keywords Kreuzschmerz ; Chronischer Schmerz ; Gehen ; Bewegungsanalyse
    Subject Gang ; Schmerzsyndrom ; Schmerzkrankheit ; Kreuzschmerzen ; Lumbaler Rückenschmerz ; Bewegungsablauf
    Subject code 617.564
    Language German
    Size XII, 210 S. : Ill., zahlr. graph. Darst., 21 cm
    Publisher Logos-Verl
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zugl. Hamburg, Univ., Diss., 2011
    HBZ-ID HT018270952
    ISBN 978-3-8325-3567-4 ; 3-8325-3567-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 A 2305 available for loan (reading room) Lesesaal EG

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  6. Book ; Thesis: Induction and phosphorylation of the small heat schock proteins HspB1/Hsp25 and HspB5/alphaB-crystallin in the rat retina after optic nerve injury

    Schmidt, Thomas

    2013  

    Author's details Thomas Schmidt
    Language English
    Size 120 Bl. : Ill.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Ulm, Univ., Diss., 2013
    HBZ-ID HT018389052
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 E 1299 order for loan Magazin

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  7. Article ; Online: S3-Leitlinie „Exokrines Pankreaskarzinom“.

    Schmidt, Thomas

    Chirurgie (Heidelberg, Germany)

    2022  Volume 93, Issue 10, Page(s) 1006

    Title translation S3 Guideline "Exocrine Pancreatic Cancer".
    MeSH term(s) Exocrine Pancreatic Insufficiency ; Humans ; Pancreatic Neoplasms/diagnosis
    Language German
    Publishing date 2022-09-26
    Publishing country Germany
    Document type News
    ISSN 2731-698X
    ISSN (online) 2731-698X
    DOI 10.1007/s00104-022-01689-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: S-Adenosylmethionine affects ERK1/2 and STAT3 pathway in androgen-independent prostate cancer cells.

    Schmidt, Thomas

    Molecular biology reports

    2022  Volume 49, Issue 6, Page(s) 4805–4817

    Abstract: Background: The most critical point in the treatment of prostate cancer is the progression towards a hormone-refractory tumour, making research on alternative therapies necessary. This study focused on the methyl donor S-adenosylmethionine (SAM), which ... ...

    Abstract Background: The most critical point in the treatment of prostate cancer is the progression towards a hormone-refractory tumour, making research on alternative therapies necessary. This study focused on the methyl donor S-adenosylmethionine (SAM), which is known to act as an antitumourigenic in several cancer cell lines. Though a genome-wide downregulation of proto-oncogenes in prostate cancer cell lines treated with SAM is obvious, the anticancer effects remain elusive. Thus, in this study, the impact of SAM treatment on the cell cycle, apoptosis and cancer-related pathways was investigated.
    Methods and results: After performing SAM treatment on prostate cancer cell lines (PC-3 and DU145), a cell-cycle arrest during the S-phase, a downregulation of cyclin A protein levels and an upregulation of p21 cell cycle inhibitor were observed. The proapoptotic Bax/Bcl-2 ratio and the caspase-3 activity were elevated; additionally, the apoptosis rate of SAM treated cells increased significantly in a time-dependent manner. Moreover, immunoblots displayed a downregulation of Erk1/2 and STAT3 phosphorylation accompanied by a reduced expression of the STAT3 protein.
    Conclusion: SAM caused changes in cancer-related pathways, probably leading to the effects on the cell cycle and apoptosis rate. These results provide deeper insights into the anticancer effects of SAM on prostate cancer cells.
    MeSH term(s) Androgens ; Apoptosis ; Cell Line, Tumor ; Humans ; MAP Kinase Signaling System ; Male ; Prostatic Neoplasms/metabolism ; S-Adenosylmethionine/metabolism ; S-Adenosylmethionine/pharmacology ; STAT3 Transcription Factor/metabolism
    Chemical Substances Androgens ; STAT3 Transcription Factor ; STAT3 protein, human ; S-Adenosylmethionine (7LP2MPO46S)
    Language English
    Publishing date 2022-03-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-022-07331-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book ; Online: Corporate Governance, Controlling und Unternehmenserfolg

    Schmidt, Timo

    2012  

    Abstract: Corporate Governance als Sicherstellung einer verantwortungsvollen und zielorientierten Unternehmensführung ist ein interdisziplinär intensiv diskutiertes Forschungsfeld. Dabei wird regelmäßig ein positiver Wirkungszusammenhang zwischen Corporate ... ...

    Abstract Corporate Governance als Sicherstellung einer verantwortungsvollen und zielorientierten Unternehmensführung ist ein interdisziplinär intensiv diskutiertes Forschungsfeld. Dabei wird regelmäßig ein positiver Wirkungszusammenhang zwischen Corporate Governance und Unternehmenserfolg unterstellt. Diese Arbeit verfolgt das Ziel, auf Basis eines empirischen Forschungsansatzes die Wirkung zwischen «guter» Corporate Governance und dem Unternehmenserfolg zu analysieren und die erfolgsfördernde Gestaltung und Umsetzung der Corporate Governance zu untersuchen. Insbesondere dem Controlling als Mitgestalter und Begleiter des Managementprozesses kommt in diesem Zusammenhang eine zentrale Bedeutung zu, die in bisherigen Forschungsarbeiten kaum untersucht wurde
    Keywords Sociology (General) ; Management. Industrial management ; Economic theory. Demography
    Size 1 electronic resource (257 p.)
    Publisher Peter Lang International Academic Publishing Group
    Document type Book ; Online
    Note German ; Open Access
    HBZ-ID HT020101021
    ISBN 9783631606919 ; 3631606915
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article ; Online: Sport- und Bewegungstherapie bei Prostatakarzinom.

    Schmidt, T / Rudolph, I

    Urologie (Heidelberg, Germany)

    2022  Volume 62, Issue 1, Page(s) 23–26

    Abstract: In the past, it was thought that physical rest was relevant for recovery of patients with prostate cancer; however, more recently there has been a paradigm shift towards physical activity parallel to oncological treatment. Diagnosis and treatment of ... ...

    Title translation Exercise and physical activity for patients with prostate cancer.
    Abstract In the past, it was thought that physical rest was relevant for recovery of patients with prostate cancer; however, more recently there has been a paradigm shift towards physical activity parallel to oncological treatment. Diagnosis and treatment of prostate cancer are associated with limitations at various levels and side effects [9], which in the course of therapy can be a potentially therapy-limiting factor associated with dose reduction, delay or even discontinuation of therapy with negative consequences for outcome and median survival. The current study situation on the topic of physical activity in prostate cancer includes various studies with differentiated physical activity interventions and treatment time points. The studies measured physiological and psychological parameters such as physical performance, incontinence, quality of life, and fatigue. Further studies also show a positive influence of exercise therapy on the prevention of long-term complications [11, 14-16]. Various international guidelines recommend physical activity during ongoing oncological therapy [5].
    MeSH term(s) Humans ; Male ; Exercise ; Exercise Therapy/adverse effects ; Fatigue/etiology ; Prostatic Neoplasms/psychology ; Prostatic Neoplasms/therapy ; Quality of Life ; Palliative Care
    Language German
    Publishing date 2022-11-29
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7072
    ISSN (online) 2731-7072
    DOI 10.1007/s00120-022-01980-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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