LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 128

Search options

  1. Book ; Thesis: Retrospektive Analyse des Auftretens infektiologischer Komplikationen bei Patienten mit neu diagnostizierter akuter melodischer Leukämie

    Tober, Romy / Bahrs, Christina / Scholl, Sebastian / Stölzel, Friedrich

    2023  

    Institution Friedrich-Schiller-Universität Jena
    Author's details von Romy Tober
    Keywords Akute myeloische Leukämie ; Infektion
    Subject Ansteckung ; Erstinfektion ; Infektionen ; AML
    Language German ; English
    Size VII, 51 Seiten, Illustrationen, Diagramme, 30 cm
    Publishing place Jena
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Friedrich-Schiller-Universität Jena, 2023
    Note Zeitschriftenaufsatz in englischer Sprache ; Kumulative Dissertation, enthält einen Zeitschriftenaufsatz ; Tag der Verteidigung: 04.07.2023
    HBZ-ID HT030625029
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2024 E 44 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Synergistic Effects of the RAR

    Fleischmann, Maximilian / Bechwar, Julia / Voigtländer, Diana / Fischer, Mike / Schnetzke, Ulf / Hochhaus, Andreas / Scholl, Sebastian

    Cancers

    2024  Volume 16, Issue 7

    Abstract: Inhibition of menin in acute myeloid leukemia (AML) harboring histone-lysine- ...

    Abstract Inhibition of menin in acute myeloid leukemia (AML) harboring histone-lysine-
    Language English
    Publishing date 2024-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16071311
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book ; Thesis: Untersuchungen zur Signaltransduktion und biologischen Funktion des Stammzellfaktorrezeptors in Zellen einer akuten myeloischen Leukämie

    Scholl, Sebastian

    2002  

    Author's details von Sebastian Scholl
    Language German
    Size [6], 96 Bl., Ill., graph. Darst., 29 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Jena, Univ., Diss., 2002
    HBZ-ID HT013378193
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2002 E 2573 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Management of Acute Myeloid Leukemia: Current Treatment Options and Future Perspectives.

    Fleischmann, Maximilian / Schnetzke, Ulf / Hochhaus, Andreas / Scholl, Sebastian

    Cancers

    2021  Volume 13, Issue 22

    Abstract: Treatment of acute myeloid leukemia (AML) has improved in recent years and several new therapeutic options have been approved. Most of them include mutation-specific approaches (e.g., gilteritinib for AML patients with ... ...

    Abstract Treatment of acute myeloid leukemia (AML) has improved in recent years and several new therapeutic options have been approved. Most of them include mutation-specific approaches (e.g., gilteritinib for AML patients with activating
    Language English
    Publishing date 2021-11-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13225722
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Book ; Online ; Thesis: Einfluss des IL-10 Polymorphismus 592 auf die Rezidivrate, das ereignisfreie Überleben und das Gesamtüberleben nach allogener hämatopoetischer Stammzelltransplantation im Kindesalter

    Schwenk, Laura [Verfasser] / Gruhn, Bernd [Gutachter] / Scholl, Sebastian [Gutachter] / Müller, Ingo [Gutachter]

    2023  

    Author's details Laura Schwenk ; Gutachter: Bernd Gruhn, Sebastian Scholl, Ingo Müller
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language Multiple languages
    Publisher Friedrich-Schiller-Universität Jena
    Publishing place Jena
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Book ; Online ; Thesis: Zusammenhang der Interleukin-6-Polymorphismen 174 und 597 bei Empfänger und Spender mit dem Therapieergebnis nach allogener hämatopoetischer Stammzelltransplantation im Kindesalter

    Wetzel, Laura [Verfasser] / Gruhn, Bernd [Gutachter] / Scholl, Sebastian [Gutachter] / Müller, Ingo [Gutachter]

    2023  

    Author's details Laura Wetzel ; Gutachter: Bernd Gruhn, Sebastian Scholl, Ingo Müller
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language Multiple languages
    Publisher Friedrich-Schiller-Universität Jena
    Publishing place Jena
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Book ; Online ; Thesis: Einflussfaktoren auf das Sprödbruchverhalten im Fallgewichtsversuch

    Scholl, Sebastian

    2014  

    Abstract: Zsfassung in dt. und engl. ... ...

    Author's details vorgelegt von Sebastian Scholl
    Abstract Zsfassung in dt. und engl. Sprache
    Language German
    Size Online-Ressource
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Techn. Hochsch., Diss.--Aachen, 2014
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book ; Online ; Thesis: Einflussfaktoren auf das Sprödbruchverhalten im Fallgewichtsversuch

    Scholl, Sebastian

    2014  

    Abstract: Zsfassung in dt. und engl. ... ...

    Author's details vorgelegt von Sebastian Scholl
    Abstract Zsfassung in dt. und engl. Sprache
    Language German
    Size Online-Ressource
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Techn. Hochsch., Diss.--Aachen, 2014
    Database Former special subject collection: coastal and deep sea fishing

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Book ; Thesis: Einflussfaktoren auf das Sprödbruchverhalten im Fallgewichtsversuch

    Scholl, Sebastian

    2014  

    Author's details vorgelegt von Sebastian Scholl
    Language German
    Size XIII, 96 S., S. XCVII-CXXIII, Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Techn. Hochsch., Diss.--Aachen, 2014
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Effective bridging strategies prior to infusion with tisagenlecleucel results in high response rates and long-term remission in relapsed/refractory large B-cell lymphoma: findings from a German monocentric study.

    Eigendorff, Farina / Filimonova, Irina / Scholl, Sebastian / Sayer-Klink, Anne / Rummler, Silke / Kunert, Christa / Pietschmann, Klaus / Wittig, Andrea / Hochhaus, Andreas / Schnetzke, Ulf

    Journal of cancer research and clinical oncology

    2024  Volume 150, Issue 5, Page(s) 224

    Abstract: Background: Incorporating chimeric antigen receptor (CAR)-T cell therapy into relapsed or refractory large B-cell lymphoma (rr LBCL) treatment algorithms has yielded remarkable response rates and durable remissions, yet a substantial portion of patients ...

    Abstract Background: Incorporating chimeric antigen receptor (CAR)-T cell therapy into relapsed or refractory large B-cell lymphoma (rr LBCL) treatment algorithms has yielded remarkable response rates and durable remissions, yet a substantial portion of patients experience progression or relapse. Variations in outcomes across treatment centers may be attributed to different bridging strategies and remission statuses preceding CAR-T cell therapy.
    Patients: Twenty-nine consecutive adult patients receiving tisagenlecleucel (tisa-cel) for rr LBCL from December 2019 to February 2023 at Jena University Hospital were analyzed.
    Results: The median age was 63, with a median of 3 prior treatments. Twenty patients (69%) were refractory to any systemic therapy before CAR-T cell treatment. Following leukapheresis, 25 patients (86%) received bridging therapy with the majority undergoing chemotherapy (52%) or combined modality therapy (32%). Radiotherapy (RT) was part of the bridging strategy in 44%, with moderately hypofractionated involved site RT (30.0 Gy/2.5 Gy) being applied most frequently (64%). Post-CAR-T infusion, the objective response rate at 30 days was 83%, with 55% achieving complete response. Twelve-month progression-free (PFS) and overall survival (OS) were 60% and 74%, respectively, with a median follow up of 11.1 months for PFS and 17.9 months for OS. Factors significantly associated with PFS were chemotherapy sensitivity pre-leukapheresis and response to bridging.
    Conclusion: The study underscores the importance of minimal tumor burden at CAR-T initiation, emphasizing the need for suitable bridging regimens. The findings advocate for clinical trials and further real-world analyses to optimize CAR-T cell therapy outcomes by identifying the most effective bridging strategies.
    MeSH term(s) Humans ; Male ; Middle Aged ; Female ; Aged ; Immunotherapy, Adoptive/methods ; Lymphoma, Large B-Cell, Diffuse/therapy ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/pathology ; Adult ; Remission Induction ; Neoplasm Recurrence, Local/therapy ; Neoplasm Recurrence, Local/pathology ; Germany ; Receptors, Antigen, T-Cell/therapeutic use ; Retrospective Studies ; Combined Modality Therapy
    Chemical Substances tisagenlecleucel (Q6C9WHR03O) ; Receptors, Antigen, T-Cell
    Language English
    Publishing date 2024-05-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 134792-5
    ISSN 1432-1335 ; 0171-5216 ; 0084-5353 ; 0943-9382
    ISSN (online) 1432-1335
    ISSN 0171-5216 ; 0084-5353 ; 0943-9382
    DOI 10.1007/s00432-024-05765-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.10: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top